FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1439, 509 aa 1>>>pF1KSDA1439 509 - 509 aa - 509 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.3395+/-0.000395; mu= -18.4333+/- 0.025 mean_var=465.6811+/-94.886, 0's: 0 Z-trim(124.4): 46 B-trim: 0 in 0/62 Lambda= 0.059433 statistics sampled from 45976 (46022) to 45976 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.54), width: 16 Scan time: 10.330 The best scores are: opt bits E(85289) NP_001128145 (OMIM: 600727) nuclear factor 1 A-typ ( 509) 3501 314.3 5.2e-85 NP_001138984 (OMIM: 600727) nuclear factor 1 A-typ ( 554) 3501 314.4 5.6e-85 NP_001138983 (OMIM: 600727) nuclear factor 1 A-typ ( 501) 3436 308.8 2.4e-83 NP_005586 (OMIM: 600727) nuclear factor 1 A-type i ( 498) 3256 293.3 1.1e-78 XP_016856851 (OMIM: 600727) PREDICTED: nuclear fac ( 490) 3191 287.8 5.1e-77 XP_011539814 (OMIM: 600727) PREDICTED: nuclear fac ( 527) 2451 224.3 6.8e-58 XP_011539817 (OMIM: 600727) PREDICTED: nuclear fac ( 516) 2444 223.7 1e-57 XP_005259975 (OMIM: 164005,602535,614753) PREDICTE ( 502) 2405 220.4 1e-56 XP_011539816 (OMIM: 600727) PREDICTED: nuclear fac ( 519) 2386 218.7 3.2e-56 XP_005259977 (OMIM: 164005,602535,614753) PREDICTE ( 494) 2346 215.3 3.3e-55 NP_001257972 (OMIM: 164005,602535,614753) nuclear ( 510) 2346 215.3 3.4e-55 XP_011526342 (OMIM: 164005,602535,614753) PREDICTE ( 518) 2346 215.3 3.4e-55 NP_002492 (OMIM: 164005,602535,614753) nuclear fac ( 441) 2041 189.1 2.2e-47 XP_006716837 (OMIM: 600728) PREDICTED: nuclear fac ( 503) 2012 186.7 1.4e-46 NP_001231931 (OMIM: 600729) nuclear factor 1 C-typ ( 508) 1988 184.6 5.9e-46 NP_001257973 (OMIM: 164005,602535,614753) nuclear ( 433) 1982 184.1 7.4e-46 XP_005259976 (OMIM: 164005,602535,614753) PREDICTE ( 500) 1983 184.2 7.8e-46 XP_006716836 (OMIM: 600728) PREDICTED: nuclear fac ( 569) 1979 183.9 1.1e-45 XP_005251524 (OMIM: 600728) PREDICTED: nuclear fac ( 570) 1978 183.8 1.2e-45 XP_016882323 (OMIM: 600729) PREDICTED: nuclear fac ( 565) 1957 182.0 4e-45 NP_995315 (OMIM: 600729) nuclear factor 1 C-type i ( 499) 1935 180.1 1.3e-44 XP_005251525 (OMIM: 600728) PREDICTED: nuclear fac ( 566) 1916 178.5 4.6e-44 XP_006722822 (OMIM: 600729) PREDICTED: nuclear fac ( 556) 1904 177.4 9.3e-44 XP_006716838 (OMIM: 600728) PREDICTED: nuclear fac ( 498) 1873 174.8 5.4e-43 NP_001177666 (OMIM: 600728) nuclear factor 1 B-typ ( 494) 1857 173.4 1.4e-42 XP_005251526 (OMIM: 600728) PREDICTED: nuclear fac ( 561) 1857 173.4 1.5e-42 XP_005259621 (OMIM: 600729) PREDICTED: nuclear fac ( 511) 1841 172.0 3.7e-42 XP_016882326 (OMIM: 164005,602535,614753) PREDICTE ( 400) 1737 163.0 1.5e-39 XP_005251527 (OMIM: 600728) PREDICTED: nuclear fac ( 487) 1716 161.3 6e-39 XP_016870228 (OMIM: 600728) PREDICTED: nuclear fac ( 419) 1706 160.4 9.6e-39 NP_005587 (OMIM: 600728) nuclear factor 1 B-type i ( 420) 1705 160.3 1e-38 NP_005588 (OMIM: 600729) nuclear factor 1 C-type i ( 428) 1700 159.9 1.4e-38 NP_001231933 (OMIM: 600729) nuclear factor 1 C-typ ( 439) 1700 159.9 1.4e-38 XP_016882324 (OMIM: 600729) PREDICTED: nuclear fac ( 439) 1700 159.9 1.4e-38 XP_006722823 (OMIM: 164005,602535,614753) PREDICTE ( 459) 1679 158.1 5.1e-38 XP_005259974 (OMIM: 164005,602535,614753) PREDICTE ( 520) 1679 158.1 5.7e-38 NP_001177667 (OMIM: 600728) nuclear factor 1 B-typ ( 446) 1652 155.8 2.5e-37 XP_016882325 (OMIM: 600729) PREDICTED: nuclear fac ( 419) 1647 155.3 3.2e-37 NP_001231934 (OMIM: 600729) nuclear factor 1 C-typ ( 430) 1647 155.3 3.3e-37 XP_016870230 (OMIM: 600728) PREDICTED: nuclear fac ( 415) 1644 155.1 3.8e-37 XP_016870229 (OMIM: 600728) PREDICTED: nuclear fac ( 416) 1643 155.0 4e-37 XP_016856852 (OMIM: 600727) PREDICTED: nuclear fac ( 271) 1100 108.3 3e-23 XP_005251528 (OMIM: 600728) PREDICTED: nuclear fac ( 318) 610 66.3 1.5e-10 XP_016870231 (OMIM: 600728) PREDICTED: nuclear fac ( 308) 534 59.8 1.3e-08 NP_001269716 (OMIM: 600728) nuclear factor 1 B-typ ( 309) 529 59.4 1.8e-08 >>NP_001128145 (OMIM: 600727) nuclear factor 1 A-type is (509 aa) initn: 3501 init1: 3501 opt: 3501 Z-score: 1647.2 bits: 314.3 E(85289): 5.2e-85 Smith-Waterman score: 3501; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 430 440 450 460 470 480 490 500 pF1KSD SPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::::::::::::::::::::: NP_001 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 490 500 >>NP_001138984 (OMIM: 600727) nuclear factor 1 A-type is (554 aa) initn: 3501 init1: 3501 opt: 3501 Z-score: 1646.7 bits: 314.4 E(85289): 5.6e-85 Smith-Waterman score: 3501; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:46-554) 10 20 30 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTW :::::::::::::::::::::::::::::: NP_001 TRWPGGCGATWQSCPSPPPRRTRIPQRPAVMYSPLCLTQDEFHPFIEALLPHVRAFAYTW 20 30 40 50 60 70 40 50 60 70 80 90 pF1KSD FNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPEYRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPEYRED 80 90 100 110 120 130 100 110 120 130 140 150 pF1KSD FVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERL 140 150 160 170 180 190 160 170 180 190 200 210 pF1KSD VKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSDADIKDQPENGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSDADIKDQPENGH 200 210 220 230 240 250 220 230 240 250 260 270 pF1KSD LGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTS 260 270 280 290 300 310 280 290 300 310 320 330 pF1KSD STSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSG 320 330 340 350 360 370 340 350 360 370 380 390 pF1KSD FSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRY 380 390 400 410 420 430 400 410 420 430 440 450 pF1KSD HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP 440 450 460 470 480 490 460 470 480 490 500 pF1KSD LPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG 500 510 520 530 540 550 >>NP_001138983 (OMIM: 600727) nuclear factor 1 A-type is (501 aa) initn: 3436 init1: 3436 opt: 3436 Z-score: 1617.2 bits: 308.8 E(85289): 2.4e-83 Smith-Waterman score: 3436; 100.0% identity (100.0% similar) in 500 aa overlap (10-509:2-501) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 420 430 440 450 460 470 490 500 pF1KSD SPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::::::::::::::::::::: NP_001 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 480 490 500 >>NP_005586 (OMIM: 600727) nuclear factor 1 A-type isofo (498 aa) initn: 3256 init1: 3256 opt: 3256 Z-score: 1533.8 bits: 293.3 E(85289): 1.1e-78 Smith-Waterman score: 3256; 96.6% identity (97.0% similar) in 494 aa overlap (1-494:1-494) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 430 440 450 460 470 480 490 500 pF1KSD SPANRFVSVGPRDPSFVNIPQQTQSWYLG :.. : :: NP_005 VAASHHPPDRPPDPFSTL 490 >>XP_016856851 (OMIM: 600727) PREDICTED: nuclear factor (490 aa) initn: 3191 init1: 3191 opt: 3191 Z-score: 1503.8 bits: 287.8 E(85289): 5.1e-77 Smith-Waterman score: 3191; 96.5% identity (96.9% similar) in 485 aa overlap (10-494:2-486) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 420 430 440 450 460 470 490 500 pF1KSD SPANRFVSVGPRDPSFVNIPQQTQSWYLG :.. : :: XP_016 VAASHHPPDRPPDPFSTL 480 490 >>XP_011539814 (OMIM: 600727) PREDICTED: nuclear factor (527 aa) initn: 3487 init1: 2416 opt: 2451 Z-score: 1160.4 bits: 224.3 E(85289): 6.8e-58 Smith-Waterman score: 3455; 96.6% identity (96.6% similar) in 527 aa overlap (1-509:1-527) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 250 260 270 280 290 300 310 320 330 340 350 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPREF 310 320 330 340 350 360 360 370 380 390 400 pF1KSD ----------------ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL :::::::::::::::::::::::::::::::::::::::::::: XP_011 KMAPSILGSPFWKVYSASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS 430 440 450 460 470 480 470 480 490 500 pF1KSD TEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG 490 500 510 520 >>XP_011539817 (OMIM: 600727) PREDICTED: nuclear factor (516 aa) initn: 3242 init1: 2416 opt: 2444 Z-score: 1157.3 bits: 223.7 E(85289): 1e-57 Smith-Waterman score: 3210; 93.2% identity (93.6% similar) in 512 aa overlap (1-494:1-512) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 250 260 270 280 290 300 310 320 330 340 350 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPREF 310 320 330 340 350 360 360 370 380 390 400 pF1KSD ----------------ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL :::::::::::::::::::::::::::::::::::::::::::: XP_011 KMAPSILGSPFWKVYSASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS 430 440 450 460 470 480 470 480 490 500 pF1KSD TEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::: :.. : :: XP_011 TEGGAASPTSPILVPGIKVAASHHPPDRPPDPFSTL 490 500 510 >>XP_005259975 (OMIM: 164005,602535,614753) PREDICTED: n (502 aa) initn: 1750 init1: 1381 opt: 2405 Z-score: 1139.4 bits: 220.4 E(85289): 1e-56 Smith-Waterman score: 2405; 70.4% identity (85.5% similar) in 517 aa overlap (1-508:1-502) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::: :::::::::::::::::::::.:::::::::::::::::::::::.::::::::: XP_005 MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :.::::.:::::::::::::::::::.:::::::.::::::::::::::::::.:::::: XP_005 LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::: :::::::::::::::::::..:::::::: XP_005 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT ::::. .:.::.: .: .::::: : ::::.::: ::::::..:::::::::::.:... XP_005 YFVHTPESGQSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 190 200 210 220 230 250 260 270 280 290 pF1KSD GPNFSLSDLESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQG ::::::.:::: :::... .. :::. : :::.::: ::..: ::.:: .. :: : : XP_005 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD RSPGSGS-QSSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG :::..:: ::::: ..:. : :..:::: : : : :: :: :::.: ::..: XP_005 RSPAAGSSQSSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAG 300 310 320 330 340 350 360 370 380 390 400 410 pF1KSD PR-ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP---QETLKEFVQLVCPD-AGQQA : .::.:: :.::::.. :::: .:::.::.:::: :..::::::.:: : .:: . XP_005 VRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQAT 360 370 380 390 400 410 420 430 440 450 460 470 pF1KSD GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT :: ::::.:::: . :: :::::.:::::::.::.: .:. .:.: .: XP_005 GQ-----PNGSGQGKVPGSFLL------PPPPPVARPVPLPMPDSKSTSTAPDGAALTPP 420 430 440 450 460 480 490 500 pF1KSD SPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::...: ..: ::::::.:::: .:.:::::.:::.: XP_005 SPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL 470 480 490 500 >>XP_011539816 (OMIM: 600727) PREDICTED: nuclear factor (519 aa) initn: 3422 init1: 2351 opt: 2386 Z-score: 1130.4 bits: 218.7 E(85289): 3.2e-56 Smith-Waterman score: 3390; 96.5% identity (96.5% similar) in 518 aa overlap (10-509:2-519) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 10 20 30 40 50 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 240 250 260 270 280 290 310 320 330 340 350 pF1KSD PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPREF 300 310 320 330 340 350 360 370 380 390 400 pF1KSD ----------------ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL :::::::::::::::::::::::::::::::::::::::::::: XP_011 KMAPSILGSPFWKVYSASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS 420 430 440 450 460 470 470 480 490 500 pF1KSD TEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG 480 490 500 510 >>XP_005259977 (OMIM: 164005,602535,614753) PREDICTED: n (494 aa) initn: 1691 init1: 1322 opt: 2346 Z-score: 1112.1 bits: 215.3 E(85289): 3.3e-55 Smith-Waterman score: 2346; 70.1% identity (85.4% similar) in 508 aa overlap (10-508:2-494) 10 20 30 40 50 60 pF1KSD MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL :::::::::::::::::.:::::::::::::::::::::::.::::::::: XP_005 MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 10 20 30 40 50 70 80 90 100 110 120 pF1KSD LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL :.::::.:::::::::::::::::::.:::::::.::::::::::::::::::.:::::: XP_005 LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA :::::::::::::::::::::::::::::: :::::::::::::::::::..:::::::: XP_005 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT ::::. .:.::.: .: .::::: : ::::.::: ::::::..:::::::::::.:... XP_005 YFVHTPESGQSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 180 190 200 210 220 230 250 260 270 280 290 pF1KSD GPNFSLSDLESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQG ::::::.:::: :::... .. :::. : :::.::: ::..: ::.:: .. :: : : XP_005 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD RSPGSGS-QSSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG :::..:: ::::: ..:. : :..:::: : : : :: :: :::.: ::..: XP_005 RSPAAGSSQSSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAG 300 310 320 330 340 360 370 380 390 400 410 pF1KSD PR-ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP---QETLKEFVQLVCPD-AGQQA : .::.:: :.::::.. :::: .:::.::.:::: :..::::::.:: : .:: . XP_005 VRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQAT 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT :: ::::.:::: . :: :::::.:::::::.::.: .:. .:.: .: XP_005 GQ-----PNGSGQGKVPGSFLL------PPPPPVARPVPLPMPDSKSTSTAPDGAALTPP 410 420 430 440 450 480 490 500 pF1KSD SPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG ::...: ..: ::::::.:::: .:.:::::.:::.: XP_005 SPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL 460 470 480 490 509 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:18:28 2016 done: Thu Nov 3 06:18:29 2016 Total Scan time: 10.330 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]