FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1441, 1237 aa
1>>>pF1KSDA1441 1237 - 1237 aa - 1237 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.7397+/-0.000438; mu= -20.2708+/- 0.027
mean_var=733.4068+/-165.330, 0's: 0 Z-trim(124.7): 31 B-trim: 2574 in 1/60
Lambda= 0.047359
statistics sampled from 46920 (46954) to 46920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.551), width: 16
Scan time: 19.550
The best scores are: opt bits E(85289)
XP_011508115 (OMIM: 610568,616833) PREDICTED: zinc (1237) 8587 603.2 3.5e-171
XP_011508114 (OMIM: 610568,616833) PREDICTED: zinc (1237) 8587 603.2 3.5e-171
NP_001291692 (OMIM: 610568,616833) zinc finger pro (1237) 8587 603.2 3.5e-171
NP_001291693 (OMIM: 610568,616833) zinc finger pro (1237) 8587 603.2 3.5e-171
NP_065883 (OMIM: 610568,616833) zinc finger protei (1237) 8587 603.2 3.5e-171
XP_005245423 (OMIM: 610568,616833) PREDICTED: zinc (1246) 8587 603.2 3.5e-171
XP_011508113 (OMIM: 610568,616833) PREDICTED: zinc (1178) 5335 380.9 2.6e-104
XP_011520550 (OMIM: 251300,613624) PREDICTED: zinc (1092) 641 60.2 8.7e-08
XP_011520548 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08
XP_005255053 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08
NP_055445 (OMIM: 251300,613624) zinc finger protei (1267) 641 60.3 9.7e-08
XP_016878223 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08
XP_011520549 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08
>>XP_011508115 (OMIM: 610568,616833) PREDICTED: zinc fin (1237 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230
>>XP_011508114 (OMIM: 610568,616833) PREDICTED: zinc fin (1237 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230
>>NP_001291692 (OMIM: 610568,616833) zinc finger protein (1237 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
NP_001 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230
>>NP_001291693 (OMIM: 610568,616833) zinc finger protein (1237 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
NP_001 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230
>>NP_065883 (OMIM: 610568,616833) zinc finger protein 68 (1237 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1150 1160 1170 1180 1190 1200
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
NP_065 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230
>>XP_005245423 (OMIM: 610568,616833) PREDICTED: zinc fin (1246 aa)
initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.1 bits: 603.2 E(85289): 3.5e-171
Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:10-1246)
10 20 30 40 50
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSES
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGRGLGSADMGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSES
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD EDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD VTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD DHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD QVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD GPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD DPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNAST
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD AMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD MVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPT
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD GYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD MQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD APVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD MMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD VFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAM
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD CDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAG
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD KGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD GLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRH
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD VRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSAR
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD AQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVE
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD DGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230
pF1KSD PLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1210 1220 1230 1240
>>XP_011508113 (OMIM: 610568,616833) PREDICTED: zinc fin (1178 aa)
initn: 5402 init1: 5256 opt: 5335 Z-score: 1993.6 bits: 380.9 E(85289): 2.6e-104
Smith-Waterman score: 8026; 95.2% identity (95.2% similar) in 1237 aa overlap (1-1237:1-1178)
10 20 30 40 50 60
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYR---------------
730 740 750 760
790 800 810 820 830 840
pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
::::::::::::::::
XP_011 --------------------------------------------LIYKCAMCDTVFTHKP
770 780
850 860 870 880 890 900
pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
790 800 810 820 830 840
910 920 930 940 950 960
pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
1090 1100 1110 1120 1130 1140
1210 1220 1230
pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
:::::::::::::::::::::::::::::::::::::
XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
1150 1160 1170
>>XP_011520550 (OMIM: 251300,613624) PREDICTED: zinc fin (1092 aa)
initn: 1951 init1: 519 opt: 641 Z-score: 260.8 bits: 60.2 E(85289): 8.7e-08
Smith-Waterman score: 1946; 35.7% identity (59.3% similar) in 1112 aa overlap (21-1052:24-1072)
10 20 30 40 50
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA
.::.:::.. ::::.: : ::. .:... .
XP_011 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGI-CMDESVSLS
10 20 30 40 50
60 70 80 90 100 110
pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP
.:..: ::: :::::::: :. :: . . . . .. :
XP_011 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP
60 70 80 90 100
120 130 140 150 160
pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE
:: .... : :. :.:: . : :... . . . : : . :: .
XP_011 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK
110 120 130 140 150 160
170 180 190 200 210 220
pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK
: ::: .:: .. .:. : ::. : : :: . . . : : :::. .
XP_011 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ
170 180 190 200 210
230 240 250 260
pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P
:.. ::. :.. : . : :. : .. . .: :: . :
XP_011 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP
220 230 240 250 260 270
270 280 290 300
pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA
.. . . :.. .. . .:: : ::. .:: : ::.:: :
XP_011 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL
280 290 300 310 320 330
310 320 330 340 350
pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS
:: .: .:. ::. ..: : :::::::::: :.: ::::..
XP_011 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP
340 350 360 370 380 390
360 370 380 390 400
pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT
::: :. :.. :. .::: . .:. : .... :. :.: :: . .
XP_011 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ
...: . . : . :. ::. :. . . : .. :.: : ::: :.:. .
XP_011 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH
460 470 480 490 500 510
470 480 490 500 510
pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL
.: .:::. . . . :. .: .... .::.:::.:.:.: .: : :::
XP_011 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL
::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.:::::::
XP_011 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG
: :::.::.::::::::.:...:.. ::: . .. :.: : :.: .:
XP_011 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG
640 650 660 670 680
640 650 660 670 680 690
pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP
..:: . :.::: .: . ..::::..: :: .:::::.
XP_011 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE
690 700 710 720 730
700 710 720 730 740 750
pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV
. : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: :::
XP_011 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY
740 750 760 770 780 790
760 770 780 790 800 810
pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF
.:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::.
XP_011 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ
800 810 820 830 840 850
820 830 840 850 860 870
pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK
. ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.:
XP_011 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK
860 870 880 890 900 910
880 890 900 910 920 930
pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP
.:: : ..: .. ... : ...: . .. ::: .. :: .::. .
XP_011 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW
920 930 940 950 960
940 950 960 970 980 990
pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL
:: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..:::
XP_011 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ
970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS
::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::..
XP_011 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLS
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSS
XP_011 QTSKVKPPGGHSPQA
1080 1090
>>XP_011520548 (OMIM: 251300,613624) PREDICTED: zinc fin (1267 aa)
initn: 2075 init1: 519 opt: 641 Z-score: 259.9 bits: 60.3 E(85289): 9.7e-08
Smith-Waterman score: 2048; 35.1% identity (58.6% similar) in 1231 aa overlap (21-1161:24-1179)
10 20 30 40 50
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA
.::.:::.. ::::.: : ::. . :... .
XP_011 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGICMD-ESVSLS
10 20 30 40 50
60 70 80 90 100 110
pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP
.:..: ::: :::::::: :. :: . . . . .. :
XP_011 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP
60 70 80 90 100
120 130 140 150 160
pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE
:: .... : :. :.:: . : :... . . . : : . :: .
XP_011 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK
110 120 130 140 150 160
170 180 190 200 210 220
pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK
: ::: .:: .. .:. : ::. : : :: . . . : : :::. .
XP_011 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ
170 180 190 200 210
230 240 250 260
pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P
:.. ::. :.. : . : :. : .. . .: :: . :
XP_011 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP
220 230 240 250 260 270
270 280 290 300
pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA
.. . . :.. .. . .:: : ::. .:: : ::.:: :
XP_011 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL
280 290 300 310 320 330
310 320 330 340 350
pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS
:: .: .:. ::. ..: : :::::::::: :.: ::::..
XP_011 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP
340 350 360 370 380 390
360 370 380 390 400
pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT
::: :. :.. :. .::: . .:. : .... :. :.: :: . .
XP_011 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ
...: . . : . :. ::. :. . . : .. :.: : ::: :.:. .
XP_011 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH
460 470 480 490 500 510
470 480 490 500 510
pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL
.: .:::. . . . :. .: .... .::.:::.:.:.: .: : :::
XP_011 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL
::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.:::::::
XP_011 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG
: :::.::.::::::::.:...:.. ::: . .. :.: : :.: .:
XP_011 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG
640 650 660 670 680
640 650 660 670 680 690
pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP
..:: . :.::: .: . ..::::..: :: .:::::.
XP_011 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE
690 700 710 720 730
700 710 720 730 740 750
pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV
. : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: :::
XP_011 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY
740 750 760 770 780 790
760 770 780 790 800 810
pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF
.:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::.
XP_011 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ
800 810 820 830 840 850
820 830 840 850 860 870
pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK
. ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.:
XP_011 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK
860 870 880 890 900 910
880 890 900 910 920 930
pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP
.:: : ..: .. ... : ...: . .. ::: .. :: .::. .
XP_011 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW
920 930 940 950 960
940 950 960 970 980 990
pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL
:: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..:::
XP_011 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ
970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS
::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::.
XP_011 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGI------
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGP---GSGGHGPL--
:. :.. : ... :: . : . ..: : . : . .: .. : :
XP_011 --RNPDLSQTS--KVKPPGGHSPQVNH--LKRPVSGVGDAPGTSNGATVSSTKRHKSLFQ
1080 1090 1100 1110 1120
1120 1130 1140 1150 1160
pF1KSD ----RYRSSSSTE-QSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKA
. ..:. : :: . .:.... ::: ::::..: .::::: :: :: :
XP_011 CAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEE
1130 1140 1150 1160 1170 1180
1170 1180 1190 1200 1210 1220
pF1KSD SALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFI
XP_011 EEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGG
1190 1200 1210 1220 1230 1240
>>XP_005255053 (OMIM: 251300,613624) PREDICTED: zinc fin (1267 aa)
initn: 2075 init1: 519 opt: 641 Z-score: 259.9 bits: 60.3 E(85289): 9.7e-08
Smith-Waterman score: 2048; 35.1% identity (58.6% similar) in 1231 aa overlap (21-1161:24-1179)
10 20 30 40 50
pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA
.::.:::.. ::::.: : ::. . :... .
XP_005 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGICMD-ESVSLS
10 20 30 40 50
60 70 80 90 100 110
pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP
.:..: ::: :::::::: :. :: . . . . .. :
XP_005 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP
60 70 80 90 100
120 130 140 150 160
pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE
:: .... : :. :.:: . : :... . . . : : . :: .
XP_005 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK
110 120 130 140 150 160
170 180 190 200 210 220
pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK
: ::: .:: .. .:. : ::. : : :: . . . : : :::. .
XP_005 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ
170 180 190 200 210
230 240 250 260
pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P
:.. ::. :.. : . : :. : .. . .: :: . :
XP_005 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP
220 230 240 250 260 270
270 280 290 300
pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA
.. . . :.. .. . .:: : ::. .:: : ::.:: :
XP_005 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL
280 290 300 310 320 330
310 320 330 340 350
pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS
:: .: .:. ::. ..: : :::::::::: :.: ::::..
XP_005 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP
340 350 360 370 380 390
360 370 380 390 400
pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT
::: :. :.. :. .::: . .:. : .... :. :.: :: . .
XP_005 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ
...: . . : . :. ::. :. . . : .. :.: : ::: :.:. .
XP_005 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH
460 470 480 490 500 510
470 480 490 500 510
pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL
.: .:::. . . . :. .: .... .::.:::.:.:.: .: : :::
XP_005 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL
::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.:::::::
XP_005 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG
: :::.::.::::::::.:...:.. ::: . .. :.: : :.: .:
XP_005 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG
640 650 660 670 680
640 650 660 670 680 690
pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP
..:: . :.::: .: . ..::::..: :: .:::::.
XP_005 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE
690 700 710 720 730
700 710 720 730 740 750
pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV
. : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: :::
XP_005 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY
740 750 760 770 780 790
760 770 780 790 800 810
pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF
.:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::.
XP_005 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ
800 810 820 830 840 850
820 830 840 850 860 870
pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK
. ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.:
XP_005 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK
860 870 880 890 900 910
880 890 900 910 920 930
pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP
.:: : ..: .. ... : ...: . .. ::: .. :: .::. .
XP_005 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW
920 930 940 950 960
940 950 960 970 980 990
pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL
:: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..:::
XP_005 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ
970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS
::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::.
XP_005 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGI------
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGP---GSGGHGPL--
:. :.. : ... :: . : . ..: : . : . .: .. : :
XP_005 --RNPDLSQTS--KVKPPGGHSPQVNH--LKRPVSGVGDAPGTSNGATVSSTKRHKSLFQ
1080 1090 1100 1110 1120
1120 1130 1140 1150 1160
pF1KSD ----RYRSSSSTE-QSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKA
. ..:. : :: . .:.... ::: ::::..: .::::: :: :: :
XP_005 CAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEE
1130 1140 1150 1160 1170 1180
1170 1180 1190 1200 1210 1220
pF1KSD SALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFI
XP_005 EEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGG
1190 1200 1210 1220 1230 1240
1237 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:19:18 2016 done: Thu Nov 3 06:19:21 2016
Total Scan time: 19.550 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]