FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1441, 1237 aa 1>>>pF1KSDA1441 1237 - 1237 aa - 1237 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.7397+/-0.000438; mu= -20.2708+/- 0.027 mean_var=733.4068+/-165.330, 0's: 0 Z-trim(124.7): 31 B-trim: 2574 in 1/60 Lambda= 0.047359 statistics sampled from 46920 (46954) to 46920 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.551), width: 16 Scan time: 19.550 The best scores are: opt bits E(85289) XP_011508115 (OMIM: 610568,616833) PREDICTED: zinc (1237) 8587 603.2 3.5e-171 XP_011508114 (OMIM: 610568,616833) PREDICTED: zinc (1237) 8587 603.2 3.5e-171 NP_001291692 (OMIM: 610568,616833) zinc finger pro (1237) 8587 603.2 3.5e-171 NP_001291693 (OMIM: 610568,616833) zinc finger pro (1237) 8587 603.2 3.5e-171 NP_065883 (OMIM: 610568,616833) zinc finger protei (1237) 8587 603.2 3.5e-171 XP_005245423 (OMIM: 610568,616833) PREDICTED: zinc (1246) 8587 603.2 3.5e-171 XP_011508113 (OMIM: 610568,616833) PREDICTED: zinc (1178) 5335 380.9 2.6e-104 XP_011520550 (OMIM: 251300,613624) PREDICTED: zinc (1092) 641 60.2 8.7e-08 XP_011520548 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08 XP_005255053 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08 NP_055445 (OMIM: 251300,613624) zinc finger protei (1267) 641 60.3 9.7e-08 XP_016878223 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08 XP_011520549 (OMIM: 251300,613624) PREDICTED: zinc (1267) 641 60.3 9.7e-08 >>XP_011508115 (OMIM: 610568,616833) PREDICTED: zinc fin (1237 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 >>XP_011508114 (OMIM: 610568,616833) PREDICTED: zinc fin (1237 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 >>NP_001291692 (OMIM: 610568,616833) zinc finger protein (1237 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: NP_001 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 >>NP_001291693 (OMIM: 610568,616833) zinc finger protein (1237 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: NP_001 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 >>NP_065883 (OMIM: 610568,616833) zinc finger protein 68 (1237 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.2 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:1-1237) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: NP_065 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 >>XP_005245423 (OMIM: 610568,616833) PREDICTED: zinc fin (1246 aa) initn: 8587 init1: 8587 opt: 8587 Z-score: 3194.1 bits: 603.2 E(85289): 3.5e-171 Smith-Waterman score: 8587; 100.0% identity (100.0% similar) in 1237 aa overlap (1-1237:10-1246) 10 20 30 40 50 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSES ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGRGLGSADMGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSES 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD EDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD VTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD DHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD QVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD GPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD DPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNAST 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD AMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD MVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD GYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD MQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD APVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCP 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD MMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD VFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAM 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD CDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAG 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD KGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSK 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD GLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRH 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD VRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSAR 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD AQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVE 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD DGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDS 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 pF1KSD PLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN :::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1210 1220 1230 1240 >>XP_011508113 (OMIM: 610568,616833) PREDICTED: zinc fin (1178 aa) initn: 5402 init1: 5256 opt: 5335 Z-score: 1993.6 bits: 380.9 E(85289): 2.6e-104 Smith-Waterman score: 8026; 95.2% identity (95.2% similar) in 1237 aa overlap (1-1237:1-1178) 10 20 30 40 50 60 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK ::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYR--------------- 730 740 750 760 790 800 810 820 830 840 pF1KSD SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP :::::::::::::::: XP_011 --------------------------------------------LIYKCAMCDTVFTHKP 770 780 850 860 870 880 890 900 pF1KSD LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT 790 800 810 820 830 840 910 920 930 940 950 960 pF1KSD PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP 850 860 870 880 890 900 970 980 990 1000 1010 1020 pF1KSD GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK 910 920 930 940 950 960 1030 1040 1050 1060 1070 1080 pF1KSD RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR 970 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KSD QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC 1030 1040 1050 1060 1070 1080 1150 1160 1170 1180 1190 1200 pF1KSD GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL 1090 1100 1110 1120 1130 1140 1210 1220 1230 pF1KSD TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN ::::::::::::::::::::::::::::::::::::: XP_011 TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN 1150 1160 1170 >>XP_011520550 (OMIM: 251300,613624) PREDICTED: zinc fin (1092 aa) initn: 1951 init1: 519 opt: 641 Z-score: 260.8 bits: 60.2 E(85289): 8.7e-08 Smith-Waterman score: 1946; 35.7% identity (59.3% similar) in 1112 aa overlap (21-1052:24-1072) 10 20 30 40 50 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA .::.:::.. ::::.: : ::. .:... . XP_011 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGI-CMDESVSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP .:..: ::: :::::::: :. :: . . . . .. : XP_011 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP 60 70 80 90 100 120 130 140 150 160 pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE :: .... : :. :.:: . : :... . . . : : . :: . XP_011 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK : ::: .:: .. .:. : ::. : : :: . . . : : :::. . XP_011 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ 170 180 190 200 210 230 240 250 260 pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P :.. ::. :.. : . : :. : .. . .: :: . : XP_011 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP 220 230 240 250 260 270 270 280 290 300 pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA .. . . :.. .. . .:: : ::. .:: : ::.:: : XP_011 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL 280 290 300 310 320 330 310 320 330 340 350 pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS :: .: .:. ::. ..: : :::::::::: :.: ::::.. XP_011 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP 340 350 360 370 380 390 360 370 380 390 400 pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT ::: :. :.. :. .::: . .:. : .... :. :.: :: . . XP_011 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA 400 410 420 430 440 450 410 420 430 440 450 460 pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ ...: . . : . :. ::. :. . . : .. :.: : ::: :.:. . XP_011 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH 460 470 480 490 500 510 470 480 490 500 510 pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL .: .:::. . . . :. .: .... .::.:::.:.:.: .: : ::: XP_011 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL 520 530 540 550 560 570 520 530 540 550 560 570 pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL ::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.::::::: XP_011 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL 580 590 600 610 620 630 580 590 600 610 620 630 pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG : :::.::.::::::::.:...:.. ::: . .. :.: : :.: .: XP_011 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP ..:: . :.::: .: . ..::::..: :: .:::::. XP_011 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE 690 700 710 720 730 700 710 720 730 740 750 pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV . : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: ::: XP_011 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF .:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::. XP_011 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK . ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.: XP_011 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP .:: : ..: .. ... : ...: . .. ::: .. :: .::. . XP_011 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW 920 930 940 950 960 940 950 960 970 980 990 pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL :: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..::: XP_011 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS ::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::.. XP_011 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLS 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSS XP_011 QTSKVKPPGGHSPQA 1080 1090 >>XP_011520548 (OMIM: 251300,613624) PREDICTED: zinc fin (1267 aa) initn: 2075 init1: 519 opt: 641 Z-score: 259.9 bits: 60.3 E(85289): 9.7e-08 Smith-Waterman score: 2048; 35.1% identity (58.6% similar) in 1231 aa overlap (21-1161:24-1179) 10 20 30 40 50 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA .::.:::.. ::::.: : ::. . :... . XP_011 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGICMD-ESVSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP .:..: ::: :::::::: :. :: . . . . .. : XP_011 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP 60 70 80 90 100 120 130 140 150 160 pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE :: .... : :. :.:: . : :... . . . : : . :: . XP_011 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK : ::: .:: .. .:. : ::. : : :: . . . : : :::. . XP_011 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ 170 180 190 200 210 230 240 250 260 pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P :.. ::. :.. : . : :. : .. . .: :: . : XP_011 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP 220 230 240 250 260 270 270 280 290 300 pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA .. . . :.. .. . .:: : ::. .:: : ::.:: : XP_011 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL 280 290 300 310 320 330 310 320 330 340 350 pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS :: .: .:. ::. ..: : :::::::::: :.: ::::.. XP_011 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP 340 350 360 370 380 390 360 370 380 390 400 pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT ::: :. :.. :. .::: . .:. : .... :. :.: :: . . XP_011 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA 400 410 420 430 440 450 410 420 430 440 450 460 pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ ...: . . : . :. ::. :. . . : .. :.: : ::: :.:. . XP_011 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH 460 470 480 490 500 510 470 480 490 500 510 pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL .: .:::. . . . :. .: .... .::.:::.:.:.: .: : ::: XP_011 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL 520 530 540 550 560 570 520 530 540 550 560 570 pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL ::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.::::::: XP_011 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL 580 590 600 610 620 630 580 590 600 610 620 630 pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG : :::.::.::::::::.:...:.. ::: . .. :.: : :.: .: XP_011 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP ..:: . :.::: .: . ..::::..: :: .:::::. XP_011 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE 690 700 710 720 730 700 710 720 730 740 750 pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV . : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: ::: XP_011 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF .:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::. XP_011 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK . ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.: XP_011 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP .:: : ..: .. ... : ...: . .. ::: .. :: .::. . XP_011 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW 920 930 940 950 960 940 950 960 970 980 990 pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL :: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..::: XP_011 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS ::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::. XP_011 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGI------ 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGP---GSGGHGPL-- :. :.. : ... :: . : . ..: : . : . .: .. : : XP_011 --RNPDLSQTS--KVKPPGGHSPQVNH--LKRPVSGVGDAPGTSNGATVSSTKRHKSLFQ 1080 1090 1100 1110 1120 1120 1130 1140 1150 1160 pF1KSD ----RYRSSSSTE-QSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKA . ..:. : :: . .:.... ::: ::::..: .::::: :: :: : XP_011 CAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEE 1130 1140 1150 1160 1170 1180 1170 1180 1190 1200 1210 1220 pF1KSD SALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFI XP_011 EEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGG 1190 1200 1210 1220 1230 1240 >>XP_005255053 (OMIM: 251300,613624) PREDICTED: zinc fin (1267 aa) initn: 2075 init1: 519 opt: 641 Z-score: 259.9 bits: 60.3 E(85289): 9.7e-08 Smith-Waterman score: 2048; 35.1% identity (58.6% similar) in 1231 aa overlap (21-1161:24-1179) 10 20 30 40 50 pF1KSD MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAA .::.:::.. ::::.: : ::. . :... . XP_005 MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKP----PGICMD-ESVSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGP .:..: ::: :::::::: :. :: . . . . .. : XP_005 HSGSAPDVPA--------------VSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLP 60 70 80 90 100 120 130 140 150 160 pF1KSD VGPH---RMQNGF--GSPEPSLPGTPHSPAPPSGGTWKE-KGMEGKTPLDLFAH--FGPE :: .... : :. :.:: . : :... . . . : : . :: . XP_005 PDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIK 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD PGDHSDP-LPP-----SAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSP-PLGALK : ::: .:: .. .:. : ::. : : :: . . . : : :::. . XP_005 P-KHSDSYFPPPLGCGAVGGPVLE-ALAKFPVP---ELHMFDHFCKKEPKPEPLPLGSQQ 170 180 190 200 210 230 240 250 260 pF1KSD ------QESCSPHH-PQVLAQQGSG----SSPK---------ATDIPASASPPPVAGV-P :.. ::. :.. : . : :. : .. . .: :: . : XP_005 EHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKP 220 230 240 250 260 270 270 280 290 300 pF1KSD FFKQSPGHQSPLASPKVPVCQPLKEED------DDEGPVDKSS------PGSPQSPSSGA .. . . :.. .. . .:: : ::. .:: : ::.:: : XP_005 AHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPL 280 290 300 310 320 330 310 320 330 340 350 pF1KSD EA---------------ADEDSNDSPASSSSRPL---KVRIKTIKTSCGNITRTVTQVPS :: .: .:. ::. ..: : :::::::::: :.: ::::.. XP_005 EATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILP 340 350 360 370 380 390 360 370 380 390 400 pF1KSD DPDPPA--PLAE--GAFLAEASLLKLSPATPTSEGPKVVSVQLGD--GTRLKGTVLPVAT ::: :. :.. :. .::: . .:. : .... :. :.: :: . . XP_005 DPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGAR-KGDESMTKA 400 410 420 430 440 450 410 420 430 440 450 460 pF1KSD IQNASTAMLMAASVARKAVVLPGG-TATSPKMIAKNVLGLVPQAL-PKADGRAGLGTGGQ ...: . . : . :. ::. :. . . : .. :.: : ::: :.:. . XP_005 SDSSSPSCSSGPRVPKGAA--PGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPH 460 470 480 490 500 510 470 480 490 500 510 pF1KSD KVNGASVVMVQPSKTATGPSTGGGTV-----ISRTQSSLVEAFNKILNSKNLLPAYRPNL .: .:::. . . . :. .: .... .::.:::.:.:.: .: : ::: XP_005 SV-AASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNL 520 530 540 550 560 570 520 530 540 550 560 570 pF1KSD SPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSL ::::.. . .: .:: ::::::::.:::::..:: :::..::: :. :.. :.::::::: XP_005 SPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSL 580 590 600 610 620 630 580 590 600 610 620 630 pF1KSD LLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEG : :::.::.::::::::.:...:.. ::: . .. :.: : :.: .: XP_005 LRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSP--------KHG 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPP ..:: . :.::: .: . ..::::..: :: .:::::. XP_005 LTSGSA----SPPPPALPLYPDP----VRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEE 690 700 710 720 730 700 710 720 730 740 750 pF1KSD APGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHV . : : : .: :.:::.::: ::::.: .. :. ::::: .: ::::..: ::: XP_005 TEGLT---CQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHY 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD SRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSF .:.::::: :.:: . .::::: ::.::::: .::::::.. :. : .:::. XP_005 ARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQ 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD QTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLK . ..:::::. :. ::..: ...:: :.. .:.::::: :::::.:: ...:.: XP_005 PHRPSQLIYKCS-CEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVK 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD NTHQSGR-LEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEP .:: : ..: .. ... : ...: . .. ::: .. :: .::. . XP_005 STHGVPRNVDELSSLQSSAD--TSSSRPGSRVPTE---PPATSVAARSSS---LPSG-RW 920 930 940 950 960 940 950 960 970 980 990 pF1KSD PRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRL :: . : : . :.. : ::: :. : :.:. ::.:::: ::...:..::: XP_005 GRPEAHRRVEARPR-LRNTG-----WTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQ 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KSD CERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQS ::.:: . :::.:.: ::. .:. : : :::: . .: .::.:... ::. XP_005 CEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGI------ 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KSD PGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGP---GSGGHGPL-- :. :.. : ... :: . : . ..: : . : . .: .. : : XP_005 --RNPDLSQTS--KVKPPGGHSPQVNH--LKRPVSGVGDAPGTSNGATVSSTKRHKSLFQ 1080 1090 1100 1110 1120 1120 1130 1140 1150 1160 pF1KSD ----RYRSSSSTE-QSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKA . ..:. : :: . .:.... ::: ::::..: .::::: :: :: : XP_005 CAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEE 1130 1140 1150 1160 1170 1180 1170 1180 1190 1200 1210 1220 pF1KSD SALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFI XP_005 EEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGG 1190 1200 1210 1220 1230 1240 1237 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:19:18 2016 done: Thu Nov 3 06:19:21 2016 Total Scan time: 19.550 Total Display time: 0.500 Function used was FASTA [36.3.4 Apr, 2011]