FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1465, 745 aa 1>>>pF1KSDA1465 745 - 745 aa - 745 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2136+/-0.000841; mu= 8.9580+/- 0.051 mean_var=202.4124+/-40.088, 0's: 0 Z-trim(114.4): 151 B-trim: 0 in 0/55 Lambda= 0.090148 statistics sampled from 14798 (14959) to 14798 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.46), width: 16 Scan time: 3.720 The best scores are: opt bits E(32554) CCDS10259.1 ISLR2 gene_id:57611|Hs108|chr15 ( 745) 5053 670.0 3.7e-192 CCDS10260.1 ISLR gene_id:3671|Hs108|chr15 ( 428) 1160 163.5 6.4e-40 >>CCDS10259.1 ISLR2 gene_id:57611|Hs108|chr15 (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3563.2 bits: 670.0 E(32554): 3.7e-192 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: CCDS10 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>CCDS10260.1 ISLR gene_id:3671|Hs108|chr15 (428 aa) initn: 1284 init1: 1000 opt: 1160 Z-score: 830.1 bits: 163.5 E(32554): 6.4e-40 Smith-Waterman score: 1315; 49.8% identity (69.6% similar) in 448 aa overlap (1-442:1-403) 10 20 30 40 50 pF1KSD MFPLRALWLVWALL-GVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLS : :. :: :::: :.: .::::: : .::. :.:::::..:. :: :.:::::::::: CCDS10 MQELHLLW--WALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD ANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDL ::.. : .::: .: . ::::::::.::: :::: ::.::.::::::.::.: :::: CCDS10 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLY .::::::::::. :.: .::::. .: ::::..:.:::.::: ::: :.::::::. CCDS10 HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQIN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD HNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSA .::: : ::.:::..:: .: ::.:: :.:::.:: .:.:.:. ::: :::. :::.:: CCDS10 ENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEE .: . :. :: :....::: .::.:.:.:.:..:::.: : . : .::. CCDS10 QPSQD--GAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSP-------NVGT-- 240 250 260 270 280 300 310 320 330 340 350 pF1KSD GEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHN :: : :. :. . ::: :.::::::.: .. : :.:.: : : CCDS10 -----DGRAL-----------PGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 290 300 310 320 330 360 370 380 390 400 410 pF1KSD ELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRG-----NSVLPSKPE :::. .:. ::.:. :: ::: : . . :.. .:.: : : :: :: CCDS10 ELGSAESSVDVALAT-------PGEGGE-DTLGRRFHGKAV-EGKGCYTVDNEVQPSGPE 340 350 360 370 380 420 430 440 450 460 470 pF1KSD GKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFN .. : : .:: ..:: CCDS10 DNV-------VIIYLSRAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF 390 400 410 420 745 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:23:44 2016 done: Thu Nov 3 06:23:45 2016 Total Scan time: 3.720 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]