FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1465, 745 aa 1>>>pF1KSDA1465 745 - 745 aa - 745 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5062+/-0.000345; mu= 6.9933+/- 0.022 mean_var=209.2700+/-42.788, 0's: 0 Z-trim(121.7): 347 B-trim: 1732 in 1/61 Lambda= 0.088659 statistics sampled from 38214 (38632) to 38214 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.453), width: 16 Scan time: 11.650 The best scores are: opt bits E(85289) XP_011520143 (OMIM: 614179) PREDICTED: immunoglobu ( 745) 5053 659.3 1.6e-188 NP_001123610 (OMIM: 614179) immunoglobulin superfa ( 745) 5053 659.3 1.6e-188 NP_065902 (OMIM: 614179) immunoglobulin superfamil ( 745) 5053 659.3 1.6e-188 NP_001123608 (OMIM: 614179) immunoglobulin superfa ( 745) 5053 659.3 1.6e-188 NP_001123609 (OMIM: 614179) immunoglobulin superfa ( 745) 5053 659.3 1.6e-188 XP_011520142 (OMIM: 614179) PREDICTED: immunoglobu ( 745) 5053 659.3 1.6e-188 XP_016877935 (OMIM: 614179) PREDICTED: immunoglobu ( 468) 3176 419.0 2.1e-116 NP_005536 (OMIM: 602059) immunoglobulin superfamil ( 428) 1160 161.1 8.4e-39 NP_958934 (OMIM: 602059) immunoglobulin superfamil ( 428) 1160 161.1 8.4e-39 NP_001013675 (OMIM: 613505) leucine-rich repeat-co ( 334) 400 63.8 1.3e-09 NP_036425 (OMIM: 269400,605158) peroxidasin homolo (1479) 404 64.9 2.8e-09 XP_016864334 (OMIM: 603746) PREDICTED: slit homolo (1495) 390 63.1 9.6e-09 XP_011512211 (OMIM: 603746) PREDICTED: slit homolo (1499) 390 63.1 9.6e-09 XP_006714049 (OMIM: 603746) PREDICTED: slit homolo (1509) 390 63.1 9.7e-09 NP_001276065 (OMIM: 603746) slit homolog 2 protein (1521) 390 63.1 9.7e-09 NP_001276064 (OMIM: 603746) slit homolog 2 protein (1525) 390 63.1 9.8e-09 NP_004778 (OMIM: 603746) slit homolog 2 protein is (1529) 390 63.1 9.8e-09 XP_005248268 (OMIM: 603746) PREDICTED: slit homolo (1533) 390 63.1 9.8e-09 NP_003052 (OMIM: 603742) slit homolog 1 protein pr (1534) 383 62.2 1.8e-08 NP_076941 (OMIM: 612810) leucine-rich repeat and f ( 635) 370 60.2 3e-08 XP_005274296 (OMIM: 612810) PREDICTED: leucine-ric ( 635) 370 60.2 3e-08 NP_003053 (OMIM: 603745) slit homolog 3 protein is (1523) 355 58.6 2.2e-07 NP_001258875 (OMIM: 603745) slit homolog 3 protein (1530) 355 58.6 2.2e-07 XP_016865268 (OMIM: 603745) PREDICTED: slit homolo (1460) 353 58.4 2.5e-07 NP_065913 (OMIM: 612807) leucine-rich repeat and f ( 771) 346 57.2 2.9e-07 XP_016882522 (OMIM: 612807) PREDICTED: leucine-ric ( 771) 346 57.2 2.9e-07 XP_005259159 (OMIM: 612807) PREDICTED: leucine-ric ( 771) 346 57.2 2.9e-07 XP_005264764 (OMIM: 269400,605158) PREDICTED: pero (1455) 349 57.8 3.6e-07 NP_001010847 (OMIM: 615212) leucine-rich repeat-co ( 294) 335 55.5 3.7e-07 XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660) 324 54.4 1.8e-06 NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660) 324 54.4 1.8e-06 XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660) 324 54.4 1.8e-06 XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660) 324 54.4 1.8e-06 XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660) 324 54.4 1.8e-06 XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 324 54.4 1.8e-06 NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545) 321 53.9 2e-06 NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545) 321 53.9 2e-06 XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545) 321 53.9 2e-06 NP_001333104 (OMIM: 612811) leucine-rich repeat an ( 466) 315 53.1 3.1e-06 NP_001317035 (OMIM: 612811) leucine-rich repeat an ( 466) 315 53.1 3.1e-06 XP_016863657 (OMIM: 615004,615058) PREDICTED: leuc ( 197) 307 51.8 3.3e-06 NP_689660 (OMIM: 612811) leucine-rich repeat and f ( 719) 315 53.2 4.3e-06 >>XP_011520143 (OMIM: 614179) PREDICTED: immunoglobulin (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: XP_011 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>NP_001123610 (OMIM: 614179) immunoglobulin superfamily (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: NP_001 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>NP_065902 (OMIM: 614179) immunoglobulin superfamily co (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: NP_065 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>NP_001123608 (OMIM: 614179) immunoglobulin superfamily (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: NP_001 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>NP_001123609 (OMIM: 614179) immunoglobulin superfamily (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: NP_001 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>XP_011520142 (OMIM: 614179) PREDICTED: immunoglobulin (745 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3505.4 bits: 659.3 E(85289): 1.6e-188 Smith-Waterman score: 5053; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 670 680 690 700 710 720 730 740 pF1KSD DRLPLGAEAVNIAQEINGNYRQTAG ::::::::::::::::::::::::: XP_011 DRLPLGAEAVNIAQEINGNYRQTAG 730 740 >>XP_016877935 (OMIM: 614179) PREDICTED: immunoglobulin (468 aa) initn: 3415 init1: 3176 opt: 3176 Z-score: 2210.7 bits: 419.0 E(85289): 2.1e-116 Smith-Waterman score: 3176; 99.8% identity (100.0% similar) in 467 aa overlap (1-467:1-467) 10 20 30 40 50 60 pF1KSD MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK ::::::::::::::::::::::::::::::::::::::::::::::. XP_016 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRHY 430 440 450 460 490 500 510 520 530 540 pF1KSD PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA >>NP_005536 (OMIM: 602059) immunoglobulin superfamily co (428 aa) initn: 1284 init1: 1000 opt: 1160 Z-score: 817.6 bits: 161.1 E(85289): 8.4e-39 Smith-Waterman score: 1315; 49.8% identity (69.6% similar) in 448 aa overlap (1-442:1-403) 10 20 30 40 50 pF1KSD MFPLRALWLVWALL-GVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLS : :. :: :::: :.: .::::: : .::. :.:::::..:. :: :.:::::::::: NP_005 MQELHLLW--WALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD ANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDL ::.. : .::: .: . ::::::::.::: :::: ::.::.::::::.::.: :::: NP_005 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLY .::::::::::. :.: .::::. .: ::::..:.:::.::: ::: :.::::::. NP_005 HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQIN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD HNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSA .::: : ::.:::..:: .: ::.:: :.:::.:: .:.:.:. ::: :::. :::.:: NP_005 ENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEE .: . :. :: :....::: .::.:.:.:.:..:::.: : . : .::. NP_005 QPSQD--GAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSP-------NVGT-- 240 250 260 270 280 300 310 320 330 340 350 pF1KSD GEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHN :: : :. :. . ::: :.::::::.: .. : :.:.: : : NP_005 -----DGRAL-----------PGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 290 300 310 320 330 360 370 380 390 400 410 pF1KSD ELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRG-----NSVLPSKPE :::. .:. ::.:. :: ::: : . . :.. .:.: : : :: :: NP_005 ELGSAESSVDVALAT-------PGEGGE-DTLGRRFHGKAV-EGKGCYTVDNEVQPSGPE 340 350 360 370 380 420 430 440 450 460 470 pF1KSD GKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFN .. : : .:: ..:: NP_005 DNV-------VIIYLSRAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF 390 400 410 420 >>NP_958934 (OMIM: 602059) immunoglobulin superfamily co (428 aa) initn: 1284 init1: 1000 opt: 1160 Z-score: 817.6 bits: 161.1 E(85289): 8.4e-39 Smith-Waterman score: 1315; 49.8% identity (69.6% similar) in 448 aa overlap (1-442:1-403) 10 20 30 40 50 pF1KSD MFPLRALWLVWALL-GVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLS : :. :: :::: :.: .::::: : .::. :.:::::..:. :: :.:::::::::: NP_958 MQELHLLW--WALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 10 20 30 40 50 60 70 80 90 100 110 pF1KSD ANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDL ::.. : .::: .: . ::::::::.::: :::: ::.::.::::::.::.: :::: NP_958 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLY .::::::::::. :.: .::::. .: ::::..:.:::.::: ::: :.::::::. NP_958 HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQIN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD HNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSA .::: : ::.:::..:: .: ::.:: :.:::.:: .:.:.:. ::: :::. :::.:: NP_958 ENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEE .: . :. :: :....::: .::.:.:.:.:..:::.: : . : .::. NP_958 QPSQD--GAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSP-------NVGT-- 240 250 260 270 280 300 310 320 330 340 350 pF1KSD GEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHN :: : :. :. . ::: :.::::::.: .. : :.:.: : : NP_958 -----DGRAL-----------PGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 290 300 310 320 330 360 370 380 390 400 410 pF1KSD ELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRG-----NSVLPSKPE :::. .:. ::.:. :: ::: : . . :.. .:.: : : :: :: NP_958 ELGSAESSVDVALAT-------PGEGGE-DTLGRRFHGKAV-EGKGCYTVDNEVQPSGPE 340 350 360 370 380 420 430 440 450 460 470 pF1KSD GKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFN .. : : .:: ..:: NP_958 DNV-------VIIYLSRAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF 390 400 410 420 >>NP_001013675 (OMIM: 613505) leucine-rich repeat-contai (334 aa) initn: 365 init1: 334 opt: 400 Z-score: 293.7 bits: 63.8 E(85289): 1.3e-09 Smith-Waterman score: 400; 35.7% identity (57.6% similar) in 238 aa overlap (8-233:22-256) 10 20 30 pF1KSD MFPLRALWLVWALLGVAGS---------CPEPCACVDKYAHQFADC : ::: .....: ::: :.:: .:.: NP_001 MRGPSWSRPRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVP---GGLASC 10 20 30 40 50 40 50 60 70 80 90 pF1KSD AYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAV . : :: :: . .: :. :.. .: :::: . . : : .: ...:. :. NP_001 SALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWG 60 70 80 90 100 110 100 110 120 130 140 150 pF1KSD LSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNN :. :. :::: : . .. . . : ::. :.. :::. : :::::: :::: ...: NP_001 LGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KSD RLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPAL .: .:::: . : ::. :.: ::. :::.: : :: . : ... :. : : NP_001 ELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KSD QGVPV--YRLPALP-CAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQL :. . :. :: : NP_001 TLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRL 240 250 260 270 280 290 745 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:23:45 2016 done: Thu Nov 3 06:23:47 2016 Total Scan time: 11.650 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]