FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1498, 3043 aa 1>>>pF1KSDA1498 3043 - 3043 aa - 3043 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.5005+/-0.00133; mu= -11.2064+/- 0.081 mean_var=672.1905+/-140.579, 0's: 0 Z-trim(115.3): 125 B-trim: 518 in 2/54 Lambda= 0.049468 statistics sampled from 15778 (15896) to 15778 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.488), width: 16 Scan time: 11.770 The best scores are: opt bits E(32554) CCDS31929.2 EP400 gene_id:57634|Hs108|chr12 (3123) 9982 729.9 5.8e-209 CCDS10689.2 SRCAP gene_id:10847|Hs108|chr16 (3230) 1582 130.4 1.7e-28 >>CCDS31929.2 EP400 gene_id:57634|Hs108|chr12 (3123 aa) initn: 12545 init1: 9954 opt: 9982 Z-score: 3865.0 bits: 729.9 E(32554): 5.8e-209 Smith-Waterman score: 19695; 97.3% identity (97.3% similar) in 3076 aa overlap (1-2995:1-3075) 10 20 30 40 50 60 pF1KSD MHHGTGPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MHHGTGPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD IQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD MAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NDLDIEEEEEEEEEEEEKSEVINDEQQALAGSLVAGAGSTVETDLFKRQQAMPSTGMAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NDLDIEEEEEEEEEEEEKSEVINDEQQALAGSLVAGAGSTVETDLFKRQQAMPSTGMAEQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD AQNATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRPKSHWDYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AQNATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRPKSHWDYLL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EEMQWMATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSRLRRIAASTARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EEMQWMATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSRLRRIAASTARE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD IECFWSNIEQVVEIKLRVELEEKRKKALNLQKVSRRGKELRPKGFDALQESSLDSGMSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IECFWSNIEQVVEIKLRVELEEKRKKALNLQKVSRRGKELRPKGFDALQESSLDSGMSGR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD KRKASISLTDDEVDDEEETIEEEEANEGVVDHQTELSNLAKEAELPLLDLMKLYEGAFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KRKASISLTDDEVDDEEETIEEEEANEGVVDHQTELSNLAKEAELPLLDLMKLYEGAFLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SSQWPRPKPDGEDTSGEEDADDCPGDRESRKDLVLIDSLFIMDQFKAAERMNIGKPNAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSQWPRPKPDGEDTSGEEDADDCPGDRESRKDLVLIDSLFIMDQFKAAERMNIGKPNAKD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD IADVTAVAEAILPKGSARVTTSVKFNAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IADVTAVAEAILPKGSARVTTSVKFNAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILAD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILSYIGSHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILSYIGSHR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD ELKAKRQEWAEPNSFHVCITSYTQFFRGLTAFTRVRWKCLVIDEMQRVKGMTERHWEAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELKAKRQEWAEPNSFHVCITSYTQFFRGLTAFTRVRWKCLVIDEMQRVKGMTERHWEAVF 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TLQSQQRLLLIDSPLHNTFLELWTMVHFLVPGISRPYLSSPLRAPSEESQDYYHKVVIRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TLQSQQRLLLIDSPLHNTFLELWTMVHFLVPGISRPYLSSPLRAPSEESQDYYHKVVIRL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD HRVTQPFILRRTKRDVEKQLTKKYEHVLKCRLSNRQKALYEDVILQPGTQEALKSGHFVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HRVTQPFILRRTKRDVEKQLTKKYEHVLKCRLSNRQKALYEDVILQPGTQEALKSGHFVN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD VLSILVRLQRICNHPGLVEPRHPGSSYVAGPLEYPSASLILKALERDFWKEADLSMFDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VLSILVRLQRICNHPGLVEPRHPGSSYVAGPLEYPSASLILKALERDFWKEADLSMFDLI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD GLENKITRHEAELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GLENKITRHEAELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGR 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 pF1KSD TVAFPSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKG----------------- ::::::::::::::::::::::::::::::::::::::::::. CCDS31 TVAFPSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRH 1450 1460 1470 1480 1490 1500 pF1KSD ------------------------------------------------------------ CCDS31 QPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQA 1510 1520 1530 1540 1550 1560 1490 1500 1510 1520 1530 pF1KSD ----GEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGS 1570 1580 1590 1600 1610 1620 1540 1550 1560 1570 1580 1590 pF1KSD VLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAV 1630 1640 1650 1660 1670 1680 1600 1610 1620 1630 1640 1650 pF1KSD NALAVGEPGTASKPASPIGGPTQEEKTRLLKERLDQIYLVNERRCSQAPVYGRDLLRICA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NALAVGEPGTASKPASPIGGPTQEEKTRLLKERLDQIYLVNERRCSQAPVYGRDLLRICA 1690 1700 1710 1720 1730 1740 1660 1670 1680 1690 1700 1710 pF1KSD LPSHGRVQWRGSLDGRRGKEAGPAHSYTSSSESPSELMLTLCRCGESLQDVIDRVAFVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LPSHGRVQWRGSLDGRRGKEAGPAHSYTSSSESPSELMLTLCRCGESLQDVIDRVAFVIP 1750 1760 1770 1780 1790 1800 1720 1730 1740 1750 1760 1770 pF1KSD PVVAAPPSLRVPRPPPLYSHRMRILRQGLREHAAPYFQQLRQTTAPRLLQFPELRLVQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PVVAAPPSLRVPRPPPLYSHRMRILRQGLREHAAPYFQQLRQTTAPRLLQFPELRLVQFD 1810 1820 1830 1840 1850 1860 1780 1790 1800 1810 1820 1830 pF1KSD SGKLEALAILLQKLKSEGRRVLILSQMILMLDILEMFLNFHYLTYVRIDENASSEQRQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SGKLEALAILLQKLKSEGRRVLILSQMILMLDILEMFLNFHYLTYVRIDENASSEQRQEL 1870 1880 1890 1900 1910 1920 1840 1850 1860 1870 1880 1890 pF1KSD MRSFNRDRRIFCAILSTHSRTTGINLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MRSFNRDRRIFCAILSTHSRTTGINLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDI 1930 1940 1950 1960 1970 1980 1900 1910 1920 1930 1940 1950 pF1KSD HIYRLVSGNSIEEKLLKNGTKDLIREVAAQGNDYSMAFLTQRTIQELFEVYSPMDDAGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HIYRLVSGNSIEEKLLKNGTKDLIREVAAQGNDYSMAFLTQRTIQELFEVYSPMDDAGFP 1990 2000 2010 2020 2030 2040 1960 1970 1980 1990 2000 2010 pF1KSD VKAEEFVVLSQEPSVTETIAPKIARPFIEALKSIEYLEEDAQKSAQEGVLGPHTDALSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VKAEEFVVLSQEPSVTETIAPKIARPFIEALKSIEYLEEDAQKSAQEGVLGPHTDALSSD 2050 2060 2070 2080 2090 2100 2020 2030 2040 2050 2060 2070 pF1KSD SENMPCDEEPSQLEELADFMEQLTPIEKYALNYLELFHTSIEQEKERNSEDAVMTAVRAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SENMPCDEEPSQLEELADFMEQLTPIEKYALNYLELFHTSIEQEKERNSEDAVMTAVRAW 2110 2120 2130 2140 2150 2160 2080 2090 2100 2110 2120 2130 pF1KSD EFWNLKTLQEREARLRLEQEEAELLTYTREDAYSMEYVYEDVDGQTEVMPLWTPPTPPQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EFWNLKTLQEREARLRLEQEEAELLTYTREDAYSMEYVYEDVDGQTEVMPLWTPPTPPQD 2170 2180 2190 2200 2210 2220 2140 2150 2160 2170 2180 2190 pF1KSD DSDIYLDSVMCLMYEATPIPEAKLPPVYVRKERKRHKTDPSAAGRKKKQRHGEAVVPPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DSDIYLDSVMCLMYEATPIPEAKLPPVYVRKERKRHKTDPSAAGRKKKQRHGEAVVPPRS 2230 2240 2250 2260 2270 2280 2200 2210 2220 2230 2240 2250 pF1KSD LFDRATPGLLKIRREGKEQKKNILLKQQVPFAKPLPTFAKPTAEPGQDNPEWLISEDWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LFDRATPGLLKIRREGKEQKKNILLKQQVPFAKPLPTFAKPTAEPGQDNPEWLISEDWAL 2290 2300 2310 2320 2330 2340 2260 2270 2280 2290 2300 2310 pF1KSD LQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEGK 2350 2360 2370 2380 2390 2400 2320 2330 2340 2350 2360 2370 pF1KSD SKNNRPLRTSQIYAQDENATHTQLYTSHFDLMKMTAGKRSPPIKPLLGMNPFQKNPKHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SKNNRPLRTSQIYAQDENATHTQLYTSHFDLMKMTAGKRSPPIKPLLGMNPFQKNPKHAS 2410 2420 2430 2440 2450 2460 2380 2390 2400 2410 2420 2430 pF1KSD VLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQ 2470 2480 2490 2500 2510 2520 2440 2450 2460 2470 2480 2490 pF1KSD PPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI 2530 2540 2550 2560 2570 2580 2500 2510 2520 2530 2540 2550 pF1KSD KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVH 2590 2600 2610 2620 2630 2640 2560 2570 2580 2590 2600 2610 pF1KSD TQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA 2650 2660 2670 2680 2690 2700 2620 2630 2640 2650 2660 2670 pF1KSD TGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQ :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: CCDS31 TGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-TTTTSQVQVPQ 2710 2720 2730 2740 2750 2680 2690 2700 2710 2720 2730 pF1KSD IQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPP 2760 2770 2780 2790 2800 2810 2740 2750 2760 2770 2780 2790 pF1KSD QQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK 2820 2830 2840 2850 2860 2870 2800 2810 2820 2830 2840 2850 pF1KSD PPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQ 2880 2890 2900 2910 2920 2930 2860 2870 2880 2890 2900 2910 pF1KSD QQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGA 2940 2950 2960 2970 2980 2990 2920 2930 2940 2950 2960 2970 pF1KSD QQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTA 3000 3010 3020 3030 3040 3050 2980 2990 3000 3010 3020 3030 pF1KSD TAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTK :::::::::::::::: CCDS31 TAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTK 3060 3070 3080 3090 3100 3110 >>CCDS10689.2 SRCAP gene_id:10847|Hs108|chr16 (3230 aa) initn: 3088 init1: 863 opt: 1582 Z-score: 624.9 bits: 130.4 E(32554): 1.7e-28 Smith-Waterman score: 2057; 32.9% identity (56.3% similar) in 1427 aa overlap (633-1787:1-1389) 610 620 630 640 650 660 pF1KSD IPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQM-VASTRLPVDPAPPCPRP .:.: . ::. : .:.. : CCDS10 MQSSPSPAHPQLPVLQTQMVSDGMTGSN-- 10 20 670 680 690 700 710 pF1KSD LPTSSTSSLAPVSGSGPGPSP---ARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQ :.: .:: .:.:... : :: :..: .. : . . : :. . . . .: . CCDS10 -PVSPASSSSPASSGAGGISPQHIAQDSSLDGPPGPPDGATVPLEGFS--LSQAADLANK 30 40 50 60 70 80 720 730 740 750 760 770 pF1KSD SPAQNATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRPKSHWDY .: . ..:. ..:: : ... ::::::: :.:: .::::. : ::::.:::: CCDS10 GP------KWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDY 90 100 110 120 130 780 790 800 810 820 830 pF1KSD LLEEMQWMATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSRLRRIAASTA : :::::...::::::::: ..:.:.:: :.:::::.. .:::...:::..:::::.. : CCDS10 LCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMA 140 150 160 170 180 190 840 850 860 870 pF1KSD REIECFWSNIEQVVEIKLRVELEEKRKKALNL---------QKVS--------------- .... ::::.:.::..: . .:::::::::.: .: : CCDS10 KDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLTSSK 200 210 220 230 240 250 pF1KSD ----------------------------------------------------------RR :: CCDS10 AGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRR 260 270 280 290 300 310 880 890 pF1KSD GKEL-RPKGFDALQE--------------------SSLDS-------------------- :: : .: :.: :: :: CCDS10 EIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEI 320 330 340 350 360 370 900 910 920 930 940 pF1KSD -----GMSGRKRKA--------SISLTDDEVDDEEETIEEEEANEGVVDHQTELSNLAKE ... :... .. ...:..:::.:: :: :: ::: :::.::.: CCDS10 KPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELARE 380 390 400 410 420 430 950 960 970 pF1KSD AELPLLDLMKLYEGAFLPSS--------------------QWP--RPKPDGEDTSGE--- .:: . .:.. : ::. :.: . : .: ::.:.. CCDS10 GELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDS 440 450 460 470 480 490 980 990 1000 pF1KSD -----EDADD----------------------------CPGDRESRKDLVLIDSLFIMDQ :: .: .:.: . : .. :. :. CCDS10 VEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDE 500 510 520 530 540 550 1010 1020 1030 1040 1050 pF1KSD FKAAERMNIGKPNA--------KDIADVTAVAEAILPKGSARVTTSVKFNAPSLLYGALR .. . : :. :.:.:..:.::.. ::: . .::.:: : :: : :: CCDS10 EQSEADAGSGPPTPGPTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLR 560 570 580 590 600 610 1060 1070 1080 1090 1100 1110 pF1KSD DYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNI .::.::::::. .:.:.:::::::: :::::.: :...:::::..:::::::..: . . CCDS10 EYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVM 620 630 640 650 660 670 1120 1130 1140 1150 1160 1170 pF1KSD LKWELELKRWCPGLKILSYIGSHRELKAKRQEWAEPNSFHVCITSYTQFFRGLTAFTRVR :.::.:::::::..:::.: :...: : ::: :..::.:::::::: .. :: : CCDS10 LNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKN 680 690 700 710 720 730 1180 1190 1200 1210 1220 1230 pF1KSD WKCLVIDEMQRVKGMTERHWEAVFTLQSQQRLLLIDSPLHNTFLELWTMVHFLVPGIS-- :. :..:: : .:.. ..:.......::.:::: .::.:...:::...:::.: . CCDS10 WRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQS 740 750 760 770 780 790 1240 1250 1260 1270 1280 1290 pF1KSD ----RPYLSSPLRAPSEESQDYYHKVVIRLHRVTQPFILRRTKRDVEKQLTKKYEHVLKC . ..:.:: . : ::.: . .: :::.: .::.:::.: :::::. ::::::..: CCDS10 HREFKEWFSNPLTGMIEGSQEYNEGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRC 800 810 820 830 840 850 1300 1310 1320 1330 1340 1350 pF1KSD RLSNRQKALYEDVILQPGTQEALKSGHFVNVLSILVRLQRICNHPGLVEPRHPGSSYVAG :::.::. ::.: . : :.:.: .:::..:..::..:...::::.: .:: : ... CCDS10 RLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITP 860 870 880 890 900 910 1360 1370 1380 1390 1400 pF1KSD PLEYPSASLILKALERDFWKEADLSMFDLIGLENKITRHEAE-LLSKKKIPRKLMEEIST . . .:::.:.: . .. :.. :::::::....:.::. .: .... :... :..: CCDS10 GICFSTASLVLRATDVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRVLLEVAT 920 930 940 950 960 970 1410 1420 1430 1440 1450 1460 pF1KSD SAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAAPTTASAAPQGPLRGR . : :: .:.:..:..::: : :::::. .. :: :: ::. : CCDS10 APDPPPRPKPVKMKVNRMLQPV---PKQEGRTVVV--VNNPR---------APLGPVPVR 980 990 1000 1010 1020 1470 1480 1490 1500 1510 1520 pF1KSD PPIAT-FSANPEAKGGEVVKI--AQL---ASITGPQSRVA-QPETPVTLQ-FQGSKFTLS :: . .::.: : : .. :.: :: .:: : .: :: : .: .. .: CCDS10 PPPGPELSAQPTP--GPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLP 1030 1040 1050 1060 1070 1080 1530 1540 1550 pF1KSD H---SQLRQLTA-GQP----LQLQGSV-----LQIVSAPG-----QPYLRAPG----PVV . : : :.. ..: :.:. . :. . :: .: :: :.. CCDS10 QVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAA 1090 1100 1110 1120 1130 1140 1560 1570 1580 1590 1600 1610 pF1KSD MQTVSQAGAVHGALGSKPPAGGPSPAP----LTP--QVGVP-GRVAVNALAVGEPGT-AS :.: . :. : . :: :.::: :.: :. .: :.: ...:. .. :. CCDS10 ATTTSTTTAT--ATTTAVPA--PTPAPQRLILSPDMQARLPSGEV----VSIGQLASLAQ 1150 1160 1170 1180 1190 1620 1630 1640 1650 1660 pF1KSD KPASPIGG--PT----QEEKTRLLKERLDQIYLVNERRCSQAPVY---GRDLLRICALPS .:.. :: : : .: : .. :. . . : .. :. . .. . :. CCDS10 RPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPA 1200 1210 1220 1230 1240 1250 1670 1680 1690 1700 1710 pF1KSD H-GRVQWRGSLDGRRGKEAGPAHSYTSSSESPSELMLTLC--RCGESLQDVIDRVAFVI- : . .: . : . :. : :.. .:. : : : . .. . : .:. CCDS10 HVALIQAVAPTPGPTPVSVLPS-STPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVR 1260 1270 1280 1290 1300 1310 1720 1730 1740 1750 1760 1770 pF1KSD -PP---VVAAPPSLRVPRPP----PLYSHRMRILRQGLREHAAPYFQQLRQTTAPRLLQF : .. .:: .:::: : . : : . .: . : : CCDS10 QAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPG--RLPTPTLGTARAPMPTPTLVR 1320 1330 1340 1350 1360 1370 1780 1790 1800 1810 1820 1830 pF1KSD PELRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMILMLDILEMFLNFHYLTYVRIDEN : :.::. : .. : : CCDS10 PLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVS 1380 1390 1400 1410 1420 1430 >-- initn: 885 init1: 735 opt: 1176 Z-score: 468.3 bits: 101.5 E(32554): 9.2e-20 Smith-Waterman score: 1185; 25.9% identity (50.8% similar) in 1554 aa overlap (1399-2844:1668-3149) 1370 1380 1390 1400 1410 1420 pF1KSD WKEADLSMFDLIGLENKITRHEAELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLF .: : ::.. : : : .: CCDS10 PGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPS 1640 1650 1660 1670 1680 1690 1430 1440 1450 1460 1470 1480 pF1KSD QPVQYGQ-KPEGRTVAFP----STHPPRTAAPTTA---SAAPQGPLRGRPPIATFSANPE : .. : .:.: :: : : . .:: : : :: :: .. : : CCDS10 QTLSLGTGNPQG---PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPL 1700 1710 1720 1730 1740 1750 1490 1500 1510 1520 1530 pF1KSD AKGGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQL--TAGQPLQLQG : .. : . .: : :. .:...: .::: . . : .:.: : : CCDS10 APASPVGPAPAHTLTLAPASSSASLLAPASVQ----TLTLSPAPVPTLGPAAAQTLALAP 1760 1770 1780 1790 1800 1810 1540 1550 1560 1570 1580 1590 pF1KSD SVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVA . : .: .: . :: ..: :. . .. :. :.. : :: . : :. . CCDS10 ASTQ------SPASQASSLVV--SASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPS 1820 1830 1840 1850 1860 1600 1610 1620 1630 1640 1650 pF1KSD VNALAVGEPGTASKPASPIGGP-----TQEEKTRLLKERLDQIYLVNERRCSQAPVYGRD . : . : : .: : .: .:.. : .:::..:. ..: . . ::::: . CCDS10 T-ATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAPVYGTE 1870 1880 1890 1900 1910 1920 1660 1670 1680 1690 1700 1710 pF1KSD LLRICALPSHGRVQWRGSLDGRRGKEAGPAH-SYTSSSESPSELMLTLCRCGESLQDVID .: .:.:: : .: : :. ::.: .. . .:. . .: . ..:...:. CCDS10 VLDFCTLP-----QPVASPIGPRS--PGPSHPTFWTYTEAAHRAVLFPQQRLDQLSEIIE 1930 1940 1950 1960 1970 1720 1730 1740 1750 1760 1770 pF1KSD RVAFVIPPVVAAPPSLRVPRPPPLYSHRMRILRQGLREHAAPYFQQLRQTTAPRLLQFPE : ::.::: : ::::.. .::: . :. ... : . : . :.. . :::. CCDS10 RFIFVMPPVEAPPPSLHACHPPPWLAPRQAAFQEQLASELWPRARPLHRIVCNMRTQFPD 1980 1990 2000 2010 2020 2030 1780 1790 1800 1810 1820 1830 pF1KSD LRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMILMLDILEMFLNFHYLTYVRIDENAS :::.:.: :::..::.::..::.::.::::..:: :::.::.::..: :.:.: .. CCDS10 LRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTR 2040 2050 2060 2070 2080 2090 1840 1850 1860 1870 1880 1890 pF1KSD SEQRQELMRSFNRDRRIFCAILSTHSRTTGINLVEADTVVFYDNDLNPVMDAKAQEWCDR :::: ::. :: :.:::: ::::.: .:.::. ::::::::.: ::.:::.::. : : CCDS10 VEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHR 2100 2110 2120 2130 2140 2150 1900 1910 1920 1930 1940 1950 pF1KSD IGRCKDIHIYRLVSGNSIEEKLLKNGT-KDLIREVAAQGNDYSMAFLTQRTIQELFEVYS ::. .:.:::::.: ..::..::... : .. ..: .:.... :.. :.::.:::.. CCDS10 IGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDM-- 2160 2170 2180 2190 2200 2210 1960 1970 1980 1990 2000 2010 pF1KSD PMDDAGFPVKAEEFVVLSQEPSVTETIAPKIARPFIEALKSIEYLEEDAQKSAQEGVLGP :... : .. : : ::.: : .. . .:: : ::: . ..: . CCDS10 PLEE---PSSSS---VPSAPEEEEETVASKQTHILEQALCRAED-EEDIRAATQAKAEQV 2220 2230 2240 2250 2260 2020 2030 2040 2050 pF1KSD HTDALSSDSENMPC------------DEEPSQLE-ELADFMEQLTPIEKYALNYLELFHT : ......: ::: :. : :.: ..:::::::.::...:: CCDS10 AELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLE 2270 2280 2290 2300 2310 2320 2060 2070 2080 2090 2100 2110 pF1KSD SIEQEKERNSEDAVMTAVRAWEFWNLKTLQEREARLRLEQEEAELLTYTREDA------- . .:. ...:. : .: . . : .: .:: ::: : :.. CCDS10 EVSREELKQAEEQVEAARKDLD-------QAKEEVFRLPQEEEEGPGAGDESSCGTGGGT 2330 2340 2350 2360 2370 2120 2130 2140 2150 2160 pF1KSD --YSMEYVYEDVDGQTEVMPLWTPPTPPQDDSDIYLDSVMCLMYEATPIPEAKLPPVYVR : . . : : . : . . :. .:: : . :. : CCDS10 HRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTP-P--RCSPARER 2380 2390 2400 2410 2420 2430 2170 2180 2190 2200 2210 2220 pF1KSD KERKRHKTDPSAAGRKKKQRHGEAVVP-PRSL-FDRATPG---LLKIRREGKEQKKNILL : . :. :. :.:: : : ..:. .: .. . . . CCDS10 VPRPAPRPRPTPASAPAAI---PALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIP 2440 2450 2460 2470 2480 2490 2230 2240 2250 2260 2270 2280 pF1KSD KQQVPFAKPLPTFAKPTAEPGQDNPEWLISEDWALLQAVKQLLELPLNLTIVS-P-AHTP . : : :. . : :. :.. . :: . .. :.. .... : . : CCDS10 PCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSV---PISASVTNLPLGLRP 2500 2510 2520 2530 2540 2290 2300 2310 2320 2330 2340 pF1KSD NWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEGKSKNNRPLRTSQIYAQDENATHTQ . .: .... : . .: . ..: :. :. . . ....: . : CCDS10 EAELCAQALASPESLELASVASSETSSLSLVP-----PKDLLPVAVEILPVSEKNLSLTP 2550 2560 2570 2580 2590 2600 2350 2360 2370 2380 2390 pF1KSD LYTS-HFDLMKMTAGKR--SPPIKPLLGMNPFQKNPKHASVLAES-GINY------DKPL : .. .. :.. .: .. . .. . ..:: :.. :.:: CCDS10 SAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPL 2610 2620 2630 2640 2650 2660 2400 2410 2420 2430 2440 pF1KSD PPIQVASLRAERIAKEKKALADQQKAQQ---PAVAQPP--------PPQPQPPPPPQQPP :. .:.... : .. .: :. :: : : :.: ::.. CCDS10 QEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRT 2670 2680 2690 2700 2710 2720 2450 2460 2470 2480 2490 pF1KSD PPLPQPQAAGS----QPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAG . .. :. ::: :: ... : . . . . : :...... : CCDS10 SADVEIRGQGTGRPGQPP-GPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPG 2730 2740 2750 2760 2770 2780 2500 2510 2520 2530 2540 2550 pF1KSD TIKTSVTGTSMPTGAVSGNVIVNTIAG-VPAATFQSINKRLASPVAPG---ALTTPGGSA . .::.. : . ..:: :.: :: .:. .: : . ::.. CCDS10 VSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGS 2790 2800 2810 2820 2830 2840 2560 2570 2580 2590 pF1KSD P-----AQVVHTQP--------PPRAVGSPATA------TPDLVSMATTQGVRAVTSVTA : : .. : : ::. ::: : .:. . . :.:. : . . CCDS10 PENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPET 2850 2860 2870 2880 2890 2900 2600 2610 2620 2630 2640 2650 pF1KSD SAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQ :. : : :. :: :. :. ..:.. . : . . .. . CCDS10 LIVADPVLEPQLIPG----PQPLGPQPVHRPNPLLSPVE-KRRRGRPPKARDLPIPGTIS 2910 2920 2930 2940 2950 2660 2670 2680 2690 2700 2710 pF1KSD QQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQ . . ..... : . . .: . :. : : . :.: ::. CCDS10 SAGDGNSESRTQPPPHPSPLTPLPPLL---VCPTATVANTVTTVTISTSPPKRKRGRPPK 2960 2970 2980 2990 3000 3010 2720 2730 2740 2750 2760 pF1KSD -PPPPQAQSAPPQPTAQVQVQTS------QPPQQQSPQLTTVTAPRPGALLTGTTVANLQ :: :. .. : ...: : . :: :. . . . . :: . :. CCDS10 NPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLE 3020 3030 3040 3050 3060 3070 2770 2780 2790 2800 2810 2820 pF1KSD VA--RLTRVPTSQLQA--QGQMQTQAPQPAQVALAKPPVVSVPAAVVSS---PGVTTLPM . : . :.. : : ... :. . :. :::::. . :. :: . :. CCDS10 AEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELT-PPVVSLTPKLRSTRLRPGSLVPPL 3080 3090 3100 3110 3120 3130 2830 2840 2850 2860 2870 2880 pF1KSD NVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKIT .. . :.: :: : ..: CCDS10 ETEKL------PRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGDG 3140 3150 3160 3170 3180 3043 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:29:31 2016 done: Thu Nov 3 06:29:34 2016 Total Scan time: 11.770 Total Display time: 0.890 Function used was FASTA [36.3.4 Apr, 2011]