Result of FASTA (omim) for
pF1KSDA1561
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1561, 1416 aa
1>>>pF1KSDA1561 1416 - 1416 aa - 1416 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.8746+/-0.000938; mu= -24.7658+/- 0.057
mean_var=872.5732+/-189.079, 0's: 0 Z-trim(114.3): 699 B-trim: 822 in 1/56
Lambda= 0.043418
statistics sampled from 23450 (24125) to 23450 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.283), width: 16
Scan time: 19.480
The best scores are: opt bits E(85289)
NP_060473 (OMIM: 612516) uveal autoantigen with co (1416) 8925 577.0 3.5e-163
XP_011520054 (OMIM: 612516) PREDICTED: uveal autoa (1436) 8767 567.1 3.4e-160
XP_016877884 (OMIM: 612516) PREDICTED: uveal autoa (1399) 8764 566.9 3.8e-160
NP_001008225 (OMIM: 612516) uveal autoantigen with (1403) 8764 566.9 3.8e-160
XP_011520056 (OMIM: 612516) PREDICTED: uveal autoa (1164) 7219 470.0 4.5e-131
XP_005254586 (OMIM: 612516) PREDICTED: uveal autoa (1392) 6706 438.0 2.4e-121
XP_016877883 (OMIM: 612516) PREDICTED: uveal autoa (1405) 6706 438.0 2.4e-121
XP_011520055 (OMIM: 612516) PREDICTED: uveal autoa (1425) 6706 438.0 2.4e-121
XP_011512318 (OMIM: 606586) PREDICTED: ankycorbin ( 986) 1112 87.4 5.8e-16
NP_001138995 (OMIM: 606586) ankycorbin isoform c [ ( 972) 1109 87.2 6.5e-16
NP_001138997 (OMIM: 606586) ankycorbin isoform d [ ( 983) 1107 87.1 7.1e-16
NP_056392 (OMIM: 606586) ankycorbin isoform a [Hom ( 980) 1105 87.0 7.8e-16
XP_011512322 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
XP_011512323 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
XP_011512320 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
NP_001138992 (OMIM: 606586) ankycorbin isoform a [ ( 980) 1105 87.0 7.8e-16
XP_006714532 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
NP_001138993 (OMIM: 606586) ankycorbin isoform a [ ( 980) 1105 87.0 7.8e-16
XP_011512321 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
XP_011512319 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
XP_011512324 (OMIM: 606586) PREDICTED: ankycorbin ( 980) 1105 87.0 7.8e-16
XP_011512327 (OMIM: 606586) PREDICTED: ankycorbin ( 957) 988 79.6 1.2e-13
NP_001138994 (OMIM: 606586) ankycorbin isoform b [ ( 951) 981 79.2 1.7e-13
XP_016864824 (OMIM: 606586) PREDICTED: ankycorbin ( 951) 981 79.2 1.7e-13
XP_016864823 (OMIM: 606586) PREDICTED: ankycorbin ( 982) 967 78.3 3.1e-13
XP_011512325 (OMIM: 606586) PREDICTED: ankycorbin ( 972) 963 78.1 3.7e-13
XP_011512326 (OMIM: 606586) PREDICTED: ankycorbin ( 972) 963 78.1 3.7e-13
XP_016864825 (OMIM: 606586) PREDICTED: ankycorbin ( 943) 839 70.3 7.8e-11
XP_016863148 (OMIM: 117143,616051) PREDICTED: cent (2551) 555 53.0 3.5e-05
XP_011529850 (OMIM: 117143,616051) PREDICTED: cent (2604) 555 53.0 3.6e-05
XP_011529849 (OMIM: 117143,616051) PREDICTED: cent (2605) 555 53.0 3.6e-05
XP_011529847 (OMIM: 117143,616051) PREDICTED: cent (2648) 555 53.0 3.6e-05
NP_001804 (OMIM: 117143,616051) centromere-associa (2701) 555 53.0 3.7e-05
NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 539 52.0 7.1e-05
XP_011529848 (OMIM: 117143,616051) PREDICTED: cent (2633) 539 52.0 7.2e-05
XP_011529846 (OMIM: 117143,616051) PREDICTED: cent (2676) 539 52.0 7.3e-05
XP_005265129 (OMIM: 602509) PREDICTED: golgin subf (2269) 532 51.5 8.8e-05
XP_005265132 (OMIM: 602509) PREDICTED: golgin subf (2214) 527 51.1 0.00011
XP_016861676 (OMIM: 602509) PREDICTED: golgin subf (2236) 527 51.1 0.00011
XP_016861677 (OMIM: 602509) PREDICTED: golgin subf (2195) 524 50.9 0.00012
NP_002069 (OMIM: 602509) golgin subfamily A member (2230) 524 51.0 0.00012
NP_001166184 (OMIM: 602509) golgin subfamily A mem (2243) 524 51.0 0.00012
XP_005265131 (OMIM: 602509) PREDICTED: golgin subf (2245) 524 51.0 0.00012
XP_006713173 (OMIM: 602509) PREDICTED: golgin subf (2250) 524 51.0 0.00012
XP_016861675 (OMIM: 602509) PREDICTED: golgin subf (2251) 524 51.0 0.00012
XP_016861674 (OMIM: 602509) PREDICTED: golgin subf (2251) 524 51.0 0.00012
XP_005265130 (OMIM: 602509) PREDICTED: golgin subf (2252) 524 51.0 0.00012
XP_016861673 (OMIM: 602509) PREDICTED: golgin subf (2276) 524 51.0 0.00013
XP_005265128 (OMIM: 602509) PREDICTED: golgin subf (2278) 524 51.0 0.00013
XP_005265127 (OMIM: 602509) PREDICTED: golgin subf (2283) 524 51.0 0.00013
>>NP_060473 (OMIM: 612516) uveal autoantigen with coiled (1416 aa)
initn: 8925 init1: 8925 opt: 8925 Z-score: 3050.6 bits: 577.0 E(85289): 3.5e-163
Smith-Waterman score: 8925; 100.0% identity (100.0% similar) in 1416 aa overlap (1-1416:1-1416)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
1330 1340 1350 1360 1370 1380
1390 1400 1410
pF1KSD IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::
NP_060 IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1390 1400 1410
>>XP_011520054 (OMIM: 612516) PREDICTED: uveal autoantig (1436 aa)
initn: 8767 init1: 8767 opt: 8767 Z-score: 2997.1 bits: 567.1 E(85289): 3.4e-160
Smith-Waterman score: 8767; 99.9% identity (99.9% similar) in 1392 aa overlap (25-1416:45-1436)
10 20 30 40 50
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSIL
: ::::::::::::::::::::::::::::
XP_011 SCVLGRFYNSALLMKLAQKGEGNLECNWKISDHAADWNKYDDRLMKAAERGDVEKVTSIL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KSD AKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHA
80 90 100 110 120 130
120 130 140 150 160 170
pF1KSD LCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLA
140 150 160 170 180 190
180 190 200 210 220 230
pF1KSD TQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGH
200 210 220 230 240 250
240 250 260 270 280 290
pF1KSD DSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQ
260 270 280 290 300 310
300 310 320 330 340 350
pF1KSD NIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAA
320 330 340 350 360 370
360 370 380 390 400 410
pF1KSD KEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIP
380 390 400 410 420 430
420 430 440 450 460 470
pF1KSD AHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAEC
440 450 460 470 480 490
480 490 500 510 520 530
pF1KSD KALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASG
500 510 520 530 540 550
540 550 560 570 580 590
pF1KSD NHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKE
560 570 580 590 600 610
600 610 620 630 640 650
pF1KSD LSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEME
620 630 640 650 660 670
660 670 680 690 700 710
pF1KSD REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT
680 690 700 710 720 730
720 730 740 750 760 770
pF1KSD LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK
740 750 760 770 780 790
780 790 800 810 820 830
pF1KSD YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC
800 810 820 830 840 850
840 850 860 870 880 890
pF1KSD GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN
860 870 880 890 900 910
900 910 920 930 940 950
pF1KSD QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYR
920 930 940 950 960 970
960 970 980 990 1000 1010
pF1KSD KGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQ
980 990 1000 1010 1020 1030
1020 1030 1040 1050 1060 1070
pF1KSD KYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKD
1040 1050 1060 1070 1080 1090
1080 1090 1100 1110 1120 1130
pF1KSD LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE
1100 1110 1120 1130 1140 1150
1140 1150 1160 1170 1180 1190
pF1KSD LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES
1160 1170 1180 1190 1200 1210
1200 1210 1220 1230 1240 1250
pF1KSD QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY
1220 1230 1240 1250 1260 1270
1260 1270 1280 1290 1300 1310
pF1KSD EEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI
1280 1290 1300 1310 1320 1330
1320 1330 1340 1350 1360 1370
pF1KSD EAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD
1340 1350 1360 1370 1380 1390
1380 1390 1400 1410
pF1KSD RQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::::::::
XP_011 RQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1400 1410 1420 1430
>>XP_016877884 (OMIM: 612516) PREDICTED: uveal autoantig (1399 aa)
initn: 8764 init1: 8764 opt: 8764 Z-score: 2996.2 bits: 566.9 E(85289): 3.8e-160
Smith-Waterman score: 8764; 100.0% identity (100.0% similar) in 1390 aa overlap (27-1416:10-1399)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
::::::::::::::::::::::::::::::::::
XP_016 MAMREKTYKHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
10 20 30 40
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
710 720 730 740 750 760
790 800 810 820 830 840
pF1KSD EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
770 780 790 800 810 820
850 860 870 880 890 900
pF1KSD IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
830 840 850 860 870 880
910 920 930 940 950 960
pF1KSD KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KSD VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KSD EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KSD EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KSD CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KSD VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KSD VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KSD ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
1310 1320 1330 1340 1350 1360
1390 1400 1410
pF1KSD IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::
XP_016 IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1370 1380 1390
>>NP_001008225 (OMIM: 612516) uveal autoantigen with coi (1403 aa)
initn: 8764 init1: 8764 opt: 8764 Z-score: 2996.2 bits: 566.9 E(85289): 3.8e-160
Smith-Waterman score: 8764; 100.0% identity (100.0% similar) in 1390 aa overlap (27-1416:14-1403)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
::::::::::::::::::::::::::::::::::
NP_001 MMNCWFSCTPKNRHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
10 20 30 40
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
710 720 730 740 750 760
790 800 810 820 830 840
pF1KSD EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
770 780 790 800 810 820
850 860 870 880 890 900
pF1KSD IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
830 840 850 860 870 880
910 920 930 940 950 960
pF1KSD KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KSD VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KSD EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KSD EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KSD CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KSD VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KSD VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KSD ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
1310 1320 1330 1340 1350 1360
1390 1400 1410
pF1KSD IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::
NP_001 IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1370 1380 1390 1400
>>XP_011520056 (OMIM: 612516) PREDICTED: uveal autoantig (1164 aa)
initn: 7218 init1: 7218 opt: 7219 Z-score: 2474.1 bits: 470.0 E(85289): 4.5e-131
Smith-Waterman score: 7219; 99.9% identity (99.9% similar) in 1159 aa overlap (259-1416:6-1164)
230 240 250 260 270 280
pF1KSD LDALGHDSSYYARIGDNLDILTLLKTASENTNK-GRELWKKGPSLQQRNLTHMQDEVNVK
::: ::::::::::::::::::::::::::
XP_011 MLIPETNKTGRELWKKGPSLQQRNLTHMQDEVNVK
10 20 30
290 300 310 320 330 340
pF1KSD SHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREK
40 50 60 70 80 90
350 360 370 380 390 400
pF1KSD LKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQ
100 110 120 130 140 150
410 420 430 440 450 460
pF1KSD CTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNEL
160 170 180 190 200 210
470 480 490 500 510 520
pF1KSD AHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHL
220 230 240 250 260 270
530 540 550 560 570 580
pF1KSD TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEE
280 290 300 310 320 330
590 600 610 620 630 640
pF1KSD NKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKA
340 350 360 370 380 390
650 660 670 680 690 700
pF1KSD KKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITE
400 410 420 430 440 450
710 720 730 740 750 760
pF1KSD LTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRK
460 470 480 490 500 510
770 780 790 800 810 820
pF1KSD LLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQL
520 530 540 550 560 570
830 840 850 860 870 880
pF1KSD SELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVK
580 590 600 610 620 630
890 900 910 920 930 940
pF1KSD KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNA
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KSD EILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKD
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KSD QLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KSD LNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGT
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KSD IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASL
880 890 900 910 920 930
1190 1200 1210 1220 1230 1240
pF1KSD REKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKL
940 950 960 970 980 990
1250 1260 1270 1280 1290 1300
pF1KSD ANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRI
1000 1010 1020 1030 1040 1050
1310 1320 1330 1340 1350 1360
pF1KSD QESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLE
1060 1070 1080 1090 1100 1110
1370 1380 1390 1400 1410
pF1KSD QQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1120 1130 1140 1150 1160
>>XP_005254586 (OMIM: 612516) PREDICTED: uveal autoantig (1392 aa)
initn: 6680 init1: 6680 opt: 6706 Z-score: 2299.5 bits: 438.0 E(85289): 2.4e-121
Smith-Waterman score: 8666; 99.2% identity (99.2% similar) in 1390 aa overlap (27-1416:14-1392)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
::::::::::::::::::::::::::::::::::
XP_005 MMNCWFSCTPKNRHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
10 20 30 40
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_005 IENEDLKERLRKIQQEQRILLDKVNGLQLQLNE-----------REKLKSLLAAKEKQHE
290 300 310 320 330
370 380 390 400 410 420
pF1KSD ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
820 830 840 850 860 870
910 920 930 940 950 960
pF1KSD KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KSD VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KSD EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KSD EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KSD CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KSD VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KSD VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KSD ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
1300 1310 1320 1330 1340 1350
1390 1400 1410
pF1KSD IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::
XP_005 IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1360 1370 1380 1390
>>XP_016877883 (OMIM: 612516) PREDICTED: uveal autoantig (1405 aa)
initn: 6680 init1: 6680 opt: 6706 Z-score: 2299.5 bits: 438.0 E(85289): 2.4e-121
Smith-Waterman score: 8827; 99.2% identity (99.2% similar) in 1416 aa overlap (1-1416:1-1405)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHE
::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 IENEDLKERLRKIQQEQRILLDKVNGLQLQLNE-----------REKLKSLLAAKEKQHE
310 320 330 340
370 380 390 400 410 420
pF1KSD ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEM
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKS
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL
710 720 730 740 750 760
790 800 810 820 830 840
pF1KSD EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEK
770 780 790 800 810 820
850 860 870 880 890 900
pF1KSD IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKI
830 840 850 860 870 880
910 920 930 940 950 960
pF1KSD KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEI
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KSD VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSE
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KSD EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYT
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KSD EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQR
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KSD CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEE
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KSD VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEE
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KSD VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KSD ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEV
1310 1320 1330 1340 1350 1360
1390 1400 1410
pF1KSD IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::
XP_016 IAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1370 1380 1390 1400
>>XP_011520055 (OMIM: 612516) PREDICTED: uveal autoantig (1425 aa)
initn: 6680 init1: 6680 opt: 6706 Z-score: 2299.4 bits: 438.0 E(85289): 2.4e-121
Smith-Waterman score: 8669; 99.1% identity (99.1% similar) in 1392 aa overlap (25-1416:45-1425)
10 20 30 40 50
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSIL
: ::::::::::::::::::::::::::::
XP_011 SCVLGRFYNSALLMKLAQKGEGNLECNWKISDHAADWNKYDDRLMKAAERGDVEKVTSIL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KSD AKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHA
80 90 100 110 120 130
120 130 140 150 160 170
pF1KSD LCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLA
140 150 160 170 180 190
180 190 200 210 220 230
pF1KSD TQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGH
200 210 220 230 240 250
240 250 260 270 280 290
pF1KSD DSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQ
260 270 280 290 300 310
300 310 320 330 340 350
pF1KSD NIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAA
::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 NIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNE-----------REKLKSLLAA
320 330 340 350 360
360 370 380 390 400 410
pF1KSD KEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD AHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAEC
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD KALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD NHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKE
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEME
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD KGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQ
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD KYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKD
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KSD EEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD EAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADAD
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KSD RQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
::::::::::::::::::::::::::::::::::::::::::
XP_011 RQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
1390 1400 1410 1420
>>XP_011512318 (OMIM: 606586) PREDICTED: ankycorbin isof (986 aa)
initn: 1469 init1: 836 opt: 1112 Z-score: 407.6 bits: 87.4 E(85289): 5.8e-16
Smith-Waterman score: 1233; 27.1% identity (61.0% similar) in 1055 aa overlap (20-1047:11-985)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
:.. ..... .::: ::::..:.: ::.:::.:.:.:::..
XP_011 MFSFGKAAFLGVSMVKGKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGAS
10 20 30 40 50
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
: : ::...::....::..::: ... ::::.:..::.:..::::::: .: :..::
XP_011 ATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
:: .::.: .: .:.:::: :: : ...:.::.: . .: ::.:: ::.::.: ..
XP_011 LQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::..:.:.:::::::.:..::::::.:: : .:::.:::.:::..:.:.::... .:.
XP_011 EICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
....: : .:: :.........:. . .:. : .
XP_011 KLSENAGIQSLL------------------------LSKISQDADLKTPTKPKQHDQVSK
240 250 260
310 320 330 340 350
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEK---
: .: .... .. ::. :. : : .. :..::.
XP_011 ISSER-----SGTPKKRKAPPPPISPTQLS---------DVSSPRSITSTPLSGKESVFF
270 280 290 300 310
360 370 380 390 400 410
pF1KSD ---QHEESLRTIEALKNRFKYFES--DHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPG
. . .:. :.:.. . : : . : ..... ::. : .:. .
XP_011 AEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQD--LLSLLQAKVASLTLHNKE
320 330 340 350 360 370
420 430 440 450 460 470
pF1KSD IPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVA
. ..:..: . : .: .. .: . : : :.. : . . : :...
XP_011 LQDKLQAKSP-KEAEADLSFDSYHSTQTDLGPSLGKP---GETSPPDSKSSPSVLIHSLG
380 390 400 410 420
480 490 500 510 520 530
pF1KSD ECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAA
. :.: .:.::.. :.:.:::. ::.. ::.:... . . .:.
XP_011 ----------KSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNN
430 440 450 460 470
540 550 560 570 580
pF1KSD SGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR----DEGKLIEEN
. . . .:...::. . ::: : :: ....:.: . . : . : .. ::.
XP_011 TEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEE
480 490 500 510 520 530
590 600 610 620 630 640
pF1KSD -KRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKA
. :...:. : :.. .:: :.: . : ... :.:..:.:::: . ...
XP_011 INVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMN
540 550 560 570 580 590
650 660 670 680 690 700
pF1KSD KKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITE
:. . . ...... :: .:: ...:....:... .: :..: ... ::.:...:
XP_011 KEKAFLFEKYQEAQEEIMKLK---DTLKSQMTQEAS-DEAEDMKEAMNRMIDELNKQVSE
600 610 620 630 640 650
710 720 730 740 750 760
pF1KSD LTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRK
:. . : :.: : : :.. .: : :. : :. ... : .
XP_011 LSQLYKEAQAELED-YRKRKSLED----VTAE----YI-------HKAEHEKLMQLTNVS
660 670 680 690
770 780 790 800 810 820
pF1KSD LLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQL
. . .: : .. :.: : .:.. :. . : .: . : .:.. :.....
XP_011 RAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKI
700 710 720 730 740 750
830 840 850 860 870 880
pF1KSD SELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVK
:.::.. . . .. : .. . : :.. .:: ...:... .:.. .. .: .
XP_011 SNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV
760 770 780 790 800 810
890 900 910 920 930 940
pF1KSD KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQS---MRKVQD
:. : ...: :.:... .::. :: :. .:.. . : :... .. :.. .
XP_011 KEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KSD SNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECER--KFKATE
:.... . : .: . :. :. :..... ..:. : .. .. ..
XP_011 SSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQ---LSYSTSSSKRQSQQLEALQQQV
880 890 900 910 920 930
1010 1020 1030 1040 1050
pF1KSD KELKDQLSE---QTQK----YSVSEEEVKKNKQEND--KLKKEIFTLQKDLRDKTVLIEK
:.:..::.: : :. : . . ......: :. :.:.:. :. .:
XP_011 KQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK
940 950 960 970 980
1060 1070 1080 1090 1100 1110
pF1KSD SHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVP
>>NP_001138995 (OMIM: 606586) ankycorbin isoform c [Homo (972 aa)
initn: 1466 init1: 833 opt: 1109 Z-score: 406.7 bits: 87.2 E(85289): 6.5e-16
Smith-Waterman score: 1230; 27.3% identity (61.0% similar) in 1049 aa overlap (26-1047:3-971)
10 20 30 40 50 60
pF1KSD MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVN
:.. .::: ::::..:.: ::.:::.:.:.:::..
NP_001 MEAKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGAS
10 20 30
70 80 90 100 110 120
pF1KSD PGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKL
: : ::...::....::..::: ... ::::.:..::.:..::::::: .: :..::
NP_001 ATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD LQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRP
:: .::.: .: .:.:::: :: : ...:.::.: . .: ::.:: ::.::.: ..
NP_001 LQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD TICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA
::..:.:.:::::::.:..::::::.:: : .:::.:::.:::..:.:.::... .:.
NP_001 EICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD RIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLE
....: : .:: :.........:. . .:. : .
NP_001 KLSENAGIQSLL------------------------LSKISQDADLKTPTKPKQHDQVSK
220 230 240 250
310 320 330 340 350
pF1KSD IENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEK---
: .: .... .. ::. :. : : .. :..::.
NP_001 ISSER-----SGTPKKRKAPPPPISPTQLS---------DVSSPRSITSTPLSGKESVFF
260 270 280 290
360 370 380 390 400 410
pF1KSD ---QHEESLRTIEALKNRFKYFES--DHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPG
. . .:. :.:.. . : : . : ..... ::. : .:. .
NP_001 AEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQD--LLSLLQAKVASLTLHNKE
300 310 320 330 340 350
420 430 440 450 460 470
pF1KSD IPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVA
. ..:..: . : .: .. .: . : : :.. : . . : :...
NP_001 LQDKLQAKSP-KEAEADLSFDSYHSTQTDLGPSLGKP---GETSPPDSKSSPSVLIHSLG
360 370 380 390 400 410
480 490 500 510 520 530
pF1KSD ECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAA
. . :.: .:.::.. :.:.:::. ::.. ::.:... . . .:.
NP_001 KSTT----------DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNN
420 430 440 450 460
540 550 560 570 580
pF1KSD SGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKR----DEGKLIEEN
. . . .:...::. . ::: : :: ....:.: . . : . : .. ::.
NP_001 TEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEE
470 480 490 500 510 520
590 600 610 620 630 640
pF1KSD -KRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKA
. :...:. : :.. .:: :.: . : ... :.:..:.:::: . ...
NP_001 INVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMN
530 540 550 560 570 580
650 660 670 680 690 700
pF1KSD KKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITE
:. . . ...... :: .:: ...:....:... .: :..: ... ::.:...:
NP_001 KEKAFLFEKYQEAQEEIMKLK---DTLKSQMTQEAS-DEAEDMKEAMNRMIDELNKQVSE
590 600 610 620 630
710 720 730 740 750 760
pF1KSD LTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRK
:. . : :.: : : :.. .: : :. : :. ... : .
NP_001 LSQLYKEAQAELED-YRKRKSLED----VTAE----YI-------HKAEHEKLMQLTNVS
640 650 660 670 680
770 780 790 800 810 820
pF1KSD LLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQL
. . .: : .. :.: : .:.. :. . : .: . : .:.. :.....
NP_001 RAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKI
690 700 710 720 730 740
830 840 850 860 870 880
pF1KSD SELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVK
:.::.. . . .. : .. . : :.. .:: ...:... .:.. .. .: .
NP_001 SNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV
750 760 770 780 790 800
890 900 910 920 930 940
pF1KSD KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQS---MRKVQD
:. : ...: :.:... .::. :: :. .:.. . : :... .. :.. .
NP_001 KEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE
810 820 830 840 850 860
950 960 970 980 990 1000
pF1KSD SNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECER--KFKATE
:.... . : .: . :. :. :..... ..:. : .. .. ..
NP_001 SSSKLEEDKDK---KINEMSKEVTKLKEALNSLSQ---LSYSTSSSKRQSQQLEALQQQV
870 880 890 900 910
1010 1020 1030 1040 1050
pF1KSD KELKDQLSE---QTQK----YSVSEEEVKKNKQEND--KLKKEIFTLQKDLRDKTVLIEK
:.:..::.: : :. : . . ......: :. :.:.:. :. .:
NP_001 KQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK
920 930 940 950 960 970
1060 1070 1080 1090 1100 1110
pF1KSD SHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVP
1416 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:06:03 2016 done: Thu Nov 3 19:06:06 2016
Total Scan time: 19.480 Total Display time: 0.890
Function used was FASTA [36.3.4 Apr, 2011]