FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1576, 419 aa 1>>>pF1KSDA1576 419 - 419 aa - 419 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8613+/-0.000344; mu= 20.5538+/- 0.022 mean_var=69.0079+/-13.844, 0's: 0 Z-trim(114.9): 60 B-trim: 109 in 1/49 Lambda= 0.154392 statistics sampled from 24952 (25013) to 24952 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.293), width: 16 Scan time: 9.150 The best scores are: opt bits E(85289) NP_006364 (OMIM: 604631) synaptic vesicle membrane ( 393) 1070 247.2 5.3e-65 XP_011539049 (OMIM: 123691) PREDICTED: quinone oxi ( 329) 487 117.3 5.8e-26 NP_001880 (OMIM: 123691) quinone oxidoreductase is ( 329) 487 117.3 5.8e-26 NP_001123514 (OMIM: 123691) quinone oxidoreductase ( 329) 487 117.3 5.8e-26 NP_001123515 (OMIM: 123691) quinone oxidoreductase ( 295) 423 103.0 1e-21 XP_016855856 (OMIM: 123691) PREDICTED: quinone oxi ( 295) 423 103.0 1e-21 NP_004872 (OMIM: 605171) quinone oxidoreductase PI ( 332) 413 100.8 5.3e-21 NP_671713 (OMIM: 605171) quinone oxidoreductase PI ( 332) 413 100.8 5.3e-21 XP_006712213 (OMIM: 605171) PREDICTED: quinone oxi ( 248) 352 87.1 5.3e-17 NP_001193731 (OMIM: 605171) quinone oxidoreductase ( 248) 352 87.1 5.3e-17 NP_057095 (OMIM: 608205) trans-2-enoyl-CoA reducta ( 373) 269 68.8 2.6e-11 XP_011539843 (OMIM: 608205) PREDICTED: trans-2-eno ( 364) 250 64.5 4.8e-10 XP_005245942 (OMIM: 608205) PREDICTED: trans-2-eno ( 401) 250 64.6 5.2e-10 XP_011539842 (OMIM: 608205) PREDICTED: trans-2-eno ( 431) 245 63.5 1.2e-09 NP_004095 (OMIM: 600212) fatty acid synthase [Homo (2511) 251 65.5 1.8e-09 XP_011521840 (OMIM: 600212) PREDICTED: fatty acid (2511) 251 65.5 1.8e-09 XP_016856905 (OMIM: 608205) PREDICTED: trans-2-eno ( 260) 239 62.0 2.1e-09 XP_016856904 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 239 62.0 2.3e-09 NP_001019903 (OMIM: 608205) trans-2-enoyl-CoA redu ( 297) 239 62.0 2.3e-09 XP_016856902 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 239 62.0 2.3e-09 XP_016856903 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 239 62.0 2.3e-09 XP_005245944 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 239 62.0 2.3e-09 XP_011539841 (OMIM: 608205) PREDICTED: trans-2-eno ( 459) 226 59.3 2.3e-08 XP_011539847 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539851 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539849 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539848 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_016856901 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539852 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539855 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539856 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_016856900 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_011539845 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 215 56.7 1.1e-07 XP_005270548 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 201 53.4 5.8e-07 NP_001128231 (OMIM: 123691) quinone oxidoreductase ( 192) 201 53.4 5.8e-07 XP_016855857 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 201 53.4 5.8e-07 NP_665857 (OMIM: 603920) quinone oxidoreductase-li ( 349) 191 51.4 4.2e-06 NP_001305675 (OMIM: 610502,616732) reticulon-4-int ( 296) 182 49.3 1.5e-05 XP_011534494 (OMIM: 610502,616732) PREDICTED: reti ( 316) 182 49.3 1.6e-05 NP_116119 (OMIM: 610502,616732) reticulon-4-intera ( 396) 182 49.4 1.9e-05 XP_016866864 (OMIM: 610502,616732) PREDICTED: reti ( 401) 171 47.0 0.0001 NP_003095 (OMIM: 182500) sorbitol dehydrogenase [H ( 357) 148 41.8 0.0033 XP_016866865 (OMIM: 610502,616732) PREDICTED: reti ( 288) 146 41.3 0.0038 NP_000659 (OMIM: 103720,103780) alcohol dehydrogen ( 375) 147 41.6 0.004 NP_000660 (OMIM: 103730,103780,168600) alcohol deh ( 375) 144 40.9 0.0063 >>NP_006364 (OMIM: 604631) synaptic vesicle membrane pro (393 aa) initn: 1051 init1: 563 opt: 1070 Z-score: 1287.9 bits: 247.2 E(85289): 5.3e-65 Smith-Waterman score: 1070; 44.0% identity (75.1% similar) in 377 aa overlap (19-390:24-393) 10 20 30 40 50 pF1KSD MAKEGVEKAEETEQMIEKEAGKEPAEGGGGDGSHRLGDAQEM-RAVVLAGFGGLN ::...: . ....:. . . . : .::.:::: . NP_006 MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD KLRLFRK--AMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEA :..: . : : : :.: .:..:::::: :::.::: : : :..::.: .:.: : NP_006 KVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD LGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVML .:..:. . :::::.. . : : : .: .. ::. :.: ::::. .:..:::..: NP_006 VGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD FEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDS-VTHLFDR :. .::. : ::::: :.::::.:..::: :: :::::::::. ::::.:.. ::: .: NP_006 FDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD NA-DYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFS .. :::.:.:.:: .:::::.: : :..:.:: .::::.: . :: .:..:: ..... NP_006 HTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD FAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIKPV .:..::. .:. ..: . :... :: .: . .:.. :. ::: .:..:::: .::: NP_006 LARTWWNQFSVTALQLLQANRAVCGF---HLGYLDGEVELVSGVVARLLALYNQGHIKPH 310 320 330 340 350 360 370 380 390 400 410 pF1KSD VDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSE .::.: .:.: .::...... :.::..: .: : : NP_006 IDSVWPFEKVADAMKQMQEKKNVGKVLL----VPGPEKEN 360 370 380 390 pF1KSD NKERMPFIQ >>XP_011539049 (OMIM: 123691) PREDICTED: quinone oxidore (329 aa) initn: 508 init1: 201 opt: 487 Z-score: 587.1 bits: 117.3 E(85289): 5.8e-26 Smith-Waterman score: 544; 32.3% identity (64.3% similar) in 347 aa overlap (42-378:8-327) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRK-AMPEPQDGE :::: . ::: . :.: :.: :.: . XP_011 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQ 10 20 30 80 90 100 110 120 130 pF1KSD LKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV . :.:.:::.: .. ..:.:. . : : .:: . .:..::.::...... ::::.. XP_011 VLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSS 40 50 60 70 80 90 140 150 160 170 180 pF1KSD NYNA-WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSA . .. .:: . . . :::.:. ..:...::. . . ::: :.. : .. : :::::.: XP_011 TISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD GGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLFD-RNADYVQEVKR-ISAE .:::: :. :. . . .. ..:::.: . . : .... ..:. :...:....:. .. . XP_011 SGGVGLAACQI-ARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD GVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIK :.::... : . : .: ::::. : :. :: . . ..:: XP_011 GIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTI------------------EINPRD 220 230 240 250 310 320 330 340 350 360 pF1KSD LYEENKVIAGFSLLNLL---FKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKE . ... : : .:.. :.: :.: :. :: .:::. : . ::.: : XP_011 TMAKESSIIGVTLFSSTKEEFQQYAAALQAGME---IGW-----LKPVIGSQYPLEKVAE 260 270 280 290 300 310 370 380 390 400 410 pF1KSD AMQRI-HDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ : . : : : ::.:: XP_011 AHENIIHGSGATGKMILLL 320 >>NP_001880 (OMIM: 123691) quinone oxidoreductase isofor (329 aa) initn: 508 init1: 201 opt: 487 Z-score: 587.1 bits: 117.3 E(85289): 5.8e-26 Smith-Waterman score: 544; 32.3% identity (64.3% similar) in 347 aa overlap (42-378:8-327) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRK-AMPEPQDGE :::: . ::: . :.: :.: :.: . NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQ 10 20 30 80 90 100 110 120 130 pF1KSD LKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV . :.:.:::.: .. ..:.:. . : : .:: . .:..::.::...... ::::.. NP_001 VLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSS 40 50 60 70 80 90 140 150 160 170 180 pF1KSD NYNA-WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSA . .. .:: . . . :::.:. ..:...::. . . ::: :.. : .. : :::::.: NP_001 TISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD GGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLFD-RNADYVQEVKR-ISAE .:::: :. :. . . .. ..:::.: . . : .... ..:. :...:....:. .. . NP_001 SGGVGLAACQI-ARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD GVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIK :.::... : . : .: ::::. : :. :: . . ..:: NP_001 GIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTI------------------EINPRD 220 230 240 250 310 320 330 340 350 360 pF1KSD LYEENKVIAGFSLLNLL---FKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKE . ... : : .:.. :.: :.: :. :: .:::. : . ::.: : NP_001 TMAKESSIIGVTLFSSTKEEFQQYAAALQAGME---IGW-----LKPVIGSQYPLEKVAE 260 270 280 290 300 310 370 380 390 400 410 pF1KSD AMQRI-HDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ : . : : : ::.:: NP_001 AHENIIHGSGATGKMILLL 320 >>NP_001123514 (OMIM: 123691) quinone oxidoreductase iso (329 aa) initn: 508 init1: 201 opt: 487 Z-score: 587.1 bits: 117.3 E(85289): 5.8e-26 Smith-Waterman score: 544; 32.3% identity (64.3% similar) in 347 aa overlap (42-378:8-327) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRK-AMPEPQDGE :::: . ::: . :.: :.: :.: . NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQ 10 20 30 80 90 100 110 120 130 pF1KSD LKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV . :.:.:::.: .. ..:.:. . : : .:: . .:..::.::...... ::::.. NP_001 VLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSS 40 50 60 70 80 90 140 150 160 170 180 pF1KSD NYNA-WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSA . .. .:: . . . :::.:. ..:...::. . . ::: :.. : .. : :::::.: NP_001 TISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD GGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLFD-RNADYVQEVKR-ISAE .:::: :. :. . . .. ..:::.: . . : .... ..:. :...:....:. .. . NP_001 SGGVGLAACQI-ARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD GVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIK :.::... : . : .: ::::. : :. :: . . ..:: NP_001 GIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTI------------------EINPRD 220 230 240 250 310 320 330 340 350 360 pF1KSD LYEENKVIAGFSLLNLL---FKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKE . ... : : .:.. :.: :.: :. :: .:::. : . ::.: : NP_001 TMAKESSIIGVTLFSSTKEEFQQYAAALQAGME---IGW-----LKPVIGSQYPLEKVAE 260 270 280 290 300 310 370 380 390 400 410 pF1KSD AMQRI-HDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ : . : : : ::.:: NP_001 AHENIIHGSGATGKMILLL 320 >>NP_001123515 (OMIM: 123691) quinone oxidoreductase iso (295 aa) initn: 452 init1: 201 opt: 423 Z-score: 510.7 bits: 103.0 E(85289): 1e-21 Smith-Waterman score: 423; 32.3% identity (72.0% similar) in 232 aa overlap (42-266:8-238) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRK-AMPEPQDGE :::: . ::: . :.: :.: :.: . NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQ 10 20 30 80 90 100 110 120 130 pF1KSD LKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV . :.:.:::.: .. ..:.:. . : : .:: . .:..::.::...... ::::.. NP_001 VLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSS 40 50 60 70 80 90 140 150 160 170 180 pF1KSD NYNA-WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSA . .. .:: . . . :::.:. ..:...::. . . ::: :.. : .. : :::::.: NP_001 TISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD GGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLFD-RNADYVQEVKRISAEG .:::: :. :. . . .. ..:::.: . . : .... ..:. :...:....: ....: NP_001 SGGVGLAACQI-ARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD -VDIV-LDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPI ..: : . ... :..:. NP_001 TIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAE 220 230 240 250 260 270 >>XP_016855856 (OMIM: 123691) PREDICTED: quinone oxidore (295 aa) initn: 452 init1: 201 opt: 423 Z-score: 510.7 bits: 103.0 E(85289): 1e-21 Smith-Waterman score: 423; 32.3% identity (72.0% similar) in 232 aa overlap (42-266:8-238) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRK-AMPEPQDGE :::: . ::: . :.: :.: :.: . XP_016 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQ 10 20 30 80 90 100 110 120 130 pF1KSD LKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV . :.:.:::.: .. ..:.:. . : : .:: . .:..::.::...... ::::.. XP_016 VLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSS 40 50 60 70 80 90 140 150 160 170 180 pF1KSD NYNA-WAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSA . .. .:: . . . :::.:. ..:...::. . . ::: :.. : .. : :::::.: XP_016 TISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD GGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLFD-RNADYVQEVKRISAEG .:::: :. :. . . .. ..:::.: . . : .... ..:. :...:....: ....: XP_016 SGGVGLAACQI-ARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD -VDIV-LDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPI ..: : . ... :..:. XP_016 TIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAE 220 230 240 250 260 270 >>NP_004872 (OMIM: 605171) quinone oxidoreductase PIG3 i (332 aa) initn: 328 init1: 183 opt: 413 Z-score: 498.0 bits: 100.8 E(85289): 5.3e-21 Smith-Waterman score: 467; 28.9% identity (62.2% similar) in 349 aa overlap (42-382:1-332) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGEL : :: . :: ..: . . : : : .::. NP_004 MLAVHFDKPGGPENLYVKEVAKPSPGEGEV 10 20 30 80 90 100 110 120 130 pF1KSD KIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGY-EIGDRVMAFV ..: : .:: ::: :::. : :: . . :.: :: : :: . .:. .::: .::.. NP_004 LLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD NYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAG .. :. : .: ... ::. .....:::.: ..::. .: :.:.. : ::.:.. NP_004 PGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGL 100 110 120 130 140 150 200 210 220 230 240 pF1KSD GGVGQAVAQLC---STVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQE-VKRISAEG .::: :. :: ...: ::. :. . .. ... . .. :. . .: .. : NP_004 SGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAG 160 170 180 190 200 250 260 270 280 290 300 pF1KSD VDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKL :...:::. :. :... : : ..::: : :. .. . :.: : NP_004 VNLILDCIGGSYWEKNVNCLALDGRWVLYGL--MGGGDINGPL-FSKL-----------L 210 220 230 240 250 310 320 330 340 350 360 pF1KSD YEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQ---KKIKPVVDSLWALEEVKEA ......:. ::: .. . :. . .:... .. ... ::.: .. . :..:: NP_004 FKRGSLIT--SLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEA 260 270 280 290 300 310 370 380 390 400 410 pF1KSD MQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ . .. ::::..:.. . NP_004 HKYMEANKNIGKIVLELPQ 320 330 >>NP_671713 (OMIM: 605171) quinone oxidoreductase PIG3 i (332 aa) initn: 328 init1: 183 opt: 413 Z-score: 498.0 bits: 100.8 E(85289): 5.3e-21 Smith-Waterman score: 467; 28.9% identity (62.2% similar) in 349 aa overlap (42-382:1-332) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGEL : :: . :: ..: . . : : : .::. NP_671 MLAVHFDKPGGPENLYVKEVAKPSPGEGEV 10 20 30 80 90 100 110 120 130 pF1KSD KIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGY-EIGDRVMAFV ..: : .:: ::: :::. : :: . . :.: :: : :: . .:. .::: .::.. NP_671 LLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD NYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAG .. :. : .: ... ::. .....:::.: ..::. .: :.:.. : ::.:.. NP_671 PGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGL 100 110 120 130 140 150 200 210 220 230 240 pF1KSD GGVGQAVAQLC---STVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQE-VKRISAEG .::: :. :: ...: ::. :. . .. ... . .. :. . .: .. : NP_671 SGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAG 160 170 180 190 200 250 260 270 280 290 300 pF1KSD VDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKL :...:::. :. :... : : ..::: : :. .. . :.: : NP_671 VNLILDCIGGSYWEKNVNCLALDGRWVLYGL--MGGGDINGPL-FSKL-----------L 210 220 230 240 250 310 320 330 340 350 360 pF1KSD YEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQ---KKIKPVVDSLWALEEVKEA ......:. ::: .. . :. . .:... .. ... ::.: .. . :..:: NP_671 FKRGSLIT--SLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEA 260 270 280 290 300 310 370 380 390 400 410 pF1KSD MQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ . .. ::::..:.. . NP_671 HKYMEANKNIGKIVLELPQ 320 330 >>XP_006712213 (OMIM: 605171) PREDICTED: quinone oxidore (248 aa) initn: 183 init1: 183 opt: 352 Z-score: 426.3 bits: 87.1 E(85289): 5.3e-17 Smith-Waterman score: 352; 31.0% identity (64.2% similar) in 226 aa overlap (42-263:1-224) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGEL : :: . :: ..: . . : : : .::. XP_006 MLAVHFDKPGGPENLYVKEVAKPSPGEGEV 10 20 30 80 90 100 110 120 130 pF1KSD KIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGY-EIGDRVMAFV ..: : .:: ::: :::. : :: . . :.: :: : :: . .:. .::: .::.. XP_006 LLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD NYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAG .. :. : .: ... ::. .....:::.: ..::. .: :.:.. : ::.:.. XP_006 PGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGL 100 110 120 130 140 150 200 210 220 230 240 pF1KSD GGVGQAVAQLC---STVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGV .::: :. :: ...: ::. :. . .. ... . .. :. . . ... . XP_006 SGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKVQA 160 170 180 190 200 250 260 270 280 290 300 pF1KSD DIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLY . . .:. : :... : XP_006 N-AGECFHGANSASLLHGGPPTSAAGSGQNLPSDRNPGGP 210 220 230 240 >>NP_001193731 (OMIM: 605171) quinone oxidoreductase PIG (248 aa) initn: 183 init1: 183 opt: 352 Z-score: 426.3 bits: 87.1 E(85289): 5.3e-17 Smith-Waterman score: 352; 31.0% identity (64.2% similar) in 226 aa overlap (42-263:1-224) 20 30 40 50 60 70 pF1KSD TEQMIEKEAGKEPAEGGGGDGSHRLGDAQEMRAVVLAGFGGLNKLRLFRKAMPEPQDGEL : :: . :: ..: . . : : : .::. NP_001 MLAVHFDKPGGPENLYVKEVAKPSPGEGEV 10 20 30 80 90 100 110 120 130 pF1KSD KIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGY-EIGDRVMAFV ..: : .:: ::: :::. : :: . . :.: :: : :: . .:. .::: .::.. NP_001 LLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD NYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAG .. :. : .: ... ::. .....:::.: ..::. .: :.:.. : ::.:.. NP_001 PGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGL 100 110 120 130 140 150 200 210 220 230 240 pF1KSD GGVGQAVAQLC---STVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGV .::: :. :: ...: ::. :. . .. ... . .. :. . . ... . NP_001 SGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKVQA 160 170 180 190 200 250 260 270 280 290 300 pF1KSD DIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLY . . .:. : :... : NP_001 N-AGECFHGANSASLLHGGPPTSAAGSGQNLPSDRNPGGP 210 220 230 240 419 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:41:34 2016 done: Thu Nov 3 06:41:36 2016 Total Scan time: 9.150 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]