FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1580, 640 aa 1>>>pF1KSDA1580 640 - 640 aa - 640 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2371+/-0.000763; mu= -1.3589+/- 0.047 mean_var=304.4858+/-62.559, 0's: 0 Z-trim(110.6): 462 B-trim: 751 in 2/55 Lambda= 0.073501 statistics sampled from 18474 (19044) to 18474 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.223), width: 16 Scan time: 10.190 The best scores are: opt bits E(85289) XP_011518544 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518546 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 NP_001245348 (OMIM: 608817) leucine-rich repeat-co ( 640) 4243 465.4 2.8e-130 XP_016873564 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873563 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873566 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 NP_065980 (OMIM: 608817) leucine-rich repeat-conta ( 640) 4243 465.4 2.8e-130 XP_016873568 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518545 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873559 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518542 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873565 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873561 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873562 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873567 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016873560 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518541 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518540 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_011518543 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 4243 465.4 2.8e-130 XP_016867994 (OMIM: 610486) PREDICTED: leucine-ric ( 653) 2295 258.8 4.3e-68 XP_011514763 (OMIM: 610486) PREDICTED: leucine-ric ( 653) 2295 258.8 4.3e-68 NP_071426 (OMIM: 610486) leucine-rich repeat-conta ( 653) 2295 258.8 4.3e-68 XP_005271426 (OMIM: 608869,615112) PREDICTED: leuc ( 958) 628 82.2 9.2e-15 NP_001288116 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288124 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288127 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 XP_016878171 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 529 71.5 9.8e-12 NP_001288128 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288118 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288121 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288126 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 XP_011520420 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 529 71.5 9.8e-12 NP_001288115 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288120 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288129 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_001288123 (OMIM: 609791) leucine-rich repeat an ( 614) 529 71.5 9.8e-12 NP_116197 (OMIM: 609791) leucine-rich repeat and i ( 620) 529 71.5 9.9e-12 NP_001299615 (OMIM: 608869,615112) leucine-rich re ( 962) 476 66.1 6.6e-10 NP_055628 (OMIM: 608869,615112) leucine-rich repea (1065) 476 66.2 7e-10 NP_689783 (OMIM: 609793) leucine-rich repeat and i ( 606) 460 64.2 1.6e-09 XP_016869792 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_016869795 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_016869796 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_011516030 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_011516026 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_011516021 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 XP_016869793 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 NP_001245211 (OMIM: 609793) leucine-rich repeat an ( 606) 460 64.2 1.6e-09 XP_016869794 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 460 64.2 1.6e-09 NP_001258 (OMIM: 602178) chondroadherin precursor ( 359) 454 63.3 1.7e-09 >>XP_011518544 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_011 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_011518546 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_011 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>NP_001245348 (OMIM: 608817) leucine-rich repeat-contai (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: NP_001 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_016873564 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_016 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_016873563 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_016 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_016873566 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_016 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>NP_065980 (OMIM: 608817) leucine-rich repeat-containin (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: NP_065 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_016873568 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_016 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_011518545 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_011 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 >>XP_016873559 (OMIM: 608817) PREDICTED: leucine-rich re (640 aa) initn: 4243 init1: 4243 opt: 4243 Z-score: 2459.8 bits: 465.4 E(85289): 2.8e-130 Smith-Waterman score: 4243; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640) 10 20 30 40 50 60 pF1KSD MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS 550 560 570 580 590 600 610 620 630 640 pF1KSD YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI :::::::::::::::::::::::::::::::::::::::: XP_016 YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI 610 620 630 640 640 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:42:10 2016 done: Thu Nov 3 06:42:11 2016 Total Scan time: 10.190 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]