FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1581, 492 aa 1>>>pF1KSDA1581 492 - 492 aa - 492 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.1904+/-0.000468; mu= 23.4673+/- 0.029 mean_var=49.1117+/- 9.925, 0's: 0 Z-trim(106.4): 56 B-trim: 0 in 0/51 Lambda= 0.183013 statistics sampled from 14486 (14526) to 14486 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.506), E-opt: 0.2 (0.17), width: 16 Scan time: 8.800 The best scores are: opt bits E(85289) NP_473368 (OMIM: 118600,123000,605145) progressive ( 492) 3210 855.8 0 XP_016865133 (OMIM: 118600,123000,605145) PREDICTE ( 464) 2989 797.4 0 XP_011512369 (OMIM: 118600,123000,605145) PREDICTE ( 350) 2211 591.9 9.9e-169 >>NP_473368 (OMIM: 118600,123000,605145) progressive ank (492 aa) initn: 3210 init1: 3210 opt: 3210 Z-score: 4573.7 bits: 855.8 E(85289): 0 Smith-Waterman score: 3210; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:1-492) 10 20 30 40 50 60 pF1KSD MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 FFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 DESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 WWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 PAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 FAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LGVHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_473 LGVHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEE 430 440 450 460 470 480 490 pF1KSD VTDIVEMREENE :::::::::::: NP_473 VTDIVEMREENE 490 >>XP_016865133 (OMIM: 118600,123000,605145) PREDICTED: p (464 aa) initn: 2989 init1: 2989 opt: 2989 Z-score: 4258.7 bits: 797.4 E(85289): 0 Smith-Waterman score: 2989; 100.0% identity (100.0% similar) in 460 aa overlap (33-492:5-464) 10 20 30 40 50 60 pF1KSD KFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFF :::::::::::::::::::::::::::::: XP_016 MTNCALNRGIAAVKEDAVEMLASYGLAYSLMKFF 10 20 30 70 80 90 100 110 120 pF1KSD TGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD SVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD HLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSFWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSFWW 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD PLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD FDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD FAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPYLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPYLG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD VHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEEVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEEVT 400 410 420 430 440 450 490 pF1KSD DIVEMREENE :::::::::: XP_016 DIVEMREENE 460 >>XP_011512369 (OMIM: 118600,123000,605145) PREDICTED: p (350 aa) initn: 2211 init1: 2211 opt: 2211 Z-score: 3150.3 bits: 591.9 E(85289): 9.9e-169 Smith-Waterman score: 2211; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337) 10 20 30 40 50 60 pF1KSD MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVD ::::::::::::::::::::::::::::::::::::: XP_011 PAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTALSPCGIPGPSVC 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPY 492 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:43:18 2016 done: Thu Nov 3 06:43:20 2016 Total Scan time: 8.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]