FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1605, 877 aa 1>>>pF1KSDA1605 877 - 877 aa - 877 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2699+/-0.000886; mu= 21.1801+/- 0.053 mean_var=69.9956+/-13.779, 0's: 0 Z-trim(106.2): 11 B-trim: 14 in 2/50 Lambda= 0.153299 statistics sampled from 8836 (8840) to 8836 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.272), width: 16 Scan time: 4.120 The best scores are: opt bits E(32554) CCDS83363.1 GBA2 gene_id:57704|Hs108|chr9 ( 877) 6169 1374.0 0 CCDS6589.1 GBA2 gene_id:57704|Hs108|chr9 ( 927) 5888 1311.9 0 >>CCDS83363.1 GBA2 gene_id:57704|Hs108|chr9 (877 aa) initn: 6169 init1: 6169 opt: 6169 Z-score: 7365.8 bits: 1374.0 E(32554): 0 Smith-Waterman score: 6169; 100.0% identity (100.0% similar) in 877 aa overlap (1-877:1-877) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG 790 800 810 820 830 840 850 860 870 pF1KSD FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS ::::::::::::::::::::::::::::::::::::: CCDS83 FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS 850 860 870 >>CCDS6589.1 GBA2 gene_id:57704|Hs108|chr9 (927 aa) initn: 5886 init1: 5886 opt: 5888 Z-score: 7029.5 bits: 1311.9 E(32554): 0 Smith-Waterman score: 5888; 99.5% identity (99.5% similar) in 842 aa overlap (1-841:1-842) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 730 740 750 760 770 780 790 800 810 820 830 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLP-S ::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS65 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWE 790 800 810 820 830 840 840 850 860 870 pF1KSD GFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS :: CCDS65 GFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKASW 850 860 870 880 890 900 877 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:47:17 2016 done: Thu Nov 3 06:47:18 2016 Total Scan time: 4.120 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]