FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1605, 877 aa 1>>>pF1KSDA1605 877 - 877 aa - 877 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9523+/-0.000375; mu= 23.1742+/- 0.023 mean_var=71.6831+/-14.450, 0's: 0 Z-trim(112.8): 22 B-trim: 83 in 1/51 Lambda= 0.151484 statistics sampled from 21845 (21866) to 21845 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.256), width: 16 Scan time: 11.500 The best scores are: opt bits E(85289) NP_001317589 (OMIM: 609471,614409) non-lysosomal g ( 877) 6169 1358.2 0 XP_016870427 (OMIM: 609471,614409) PREDICTED: non- ( 883) 6147 1353.3 0 NP_065995 (OMIM: 609471,614409) non-lysosomal gluc ( 927) 5888 1296.8 0 XP_006716872 (OMIM: 609471,614409) PREDICTED: non- ( 933) 5866 1292.0 0 XP_016870428 (OMIM: 609471,614409) PREDICTED: non- ( 855) 4461 984.9 0 XP_016870426 (OMIM: 609471,614409) PREDICTED: non- ( 905) 4461 984.9 0 XP_005251583 (OMIM: 609471,614409) PREDICTED: non- ( 911) 4439 980.1 0 XP_016870430 (OMIM: 609471,614409) PREDICTED: non- ( 804) 4273 943.8 0 XP_016870429 (OMIM: 609471,614409) PREDICTED: non- ( 854) 3992 882.4 0 XP_016870434 (OMIM: 609471,614409) PREDICTED: non- ( 742) 3980 879.7 0 XP_016870433 (OMIM: 609471,614409) PREDICTED: non- ( 748) 3980 879.7 0 XP_016870432 (OMIM: 609471,614409) PREDICTED: non- ( 776) 3980 879.7 0 XP_016870431 (OMIM: 609471,614409) PREDICTED: non- ( 782) 3980 879.7 0 XP_016870435 (OMIM: 609471,614409) PREDICTED: non- ( 640) 3816 843.8 0 >>NP_001317589 (OMIM: 609471,614409) non-lysosomal gluco (877 aa) initn: 6169 init1: 6169 opt: 6169 Z-score: 7279.9 bits: 1358.2 E(85289): 0 Smith-Waterman score: 6169; 100.0% identity (100.0% similar) in 877 aa overlap (1-877:1-877) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG 790 800 810 820 830 840 850 860 870 pF1KSD FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS ::::::::::::::::::::::::::::::::::::: NP_001 FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS 850 860 870 >>XP_016870427 (OMIM: 609471,614409) PREDICTED: non-lyso (883 aa) initn: 4793 init1: 4793 opt: 6147 Z-score: 7253.9 bits: 1353.3 E(85289): 0 Smith-Waterman score: 6147; 99.3% identity (99.3% similar) in 883 aa overlap (1-877:1-883) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 pF1KSD QHRTVIADQ------FTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR ::::::::: ::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHRTVIADQPICPLKFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMES 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ 790 800 810 820 830 840 840 850 860 870 pF1KSD ELLPSGFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS ::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLPSGFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS 850 860 870 880 >>NP_065995 (OMIM: 609471,614409) non-lysosomal glucosyl (927 aa) initn: 5886 init1: 5886 opt: 5888 Z-score: 6947.7 bits: 1296.8 E(85289): 0 Smith-Waterman score: 5888; 99.5% identity (99.5% similar) in 842 aa overlap (1-841:1-842) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 730 740 750 760 770 780 790 800 810 820 830 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLP-S ::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_065 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWE 790 800 810 820 830 840 840 850 860 870 pF1KSD GFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS :: NP_065 GFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKASW 850 860 870 880 890 900 >>XP_006716872 (OMIM: 609471,614409) PREDICTED: non-lyso (933 aa) initn: 4510 init1: 4510 opt: 5866 Z-score: 6921.7 bits: 1292.0 E(85289): 0 Smith-Waterman score: 5866; 98.8% identity (98.8% similar) in 848 aa overlap (1-841:1-848) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 pF1KSD QHRTVIADQ------FTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR ::::::::: ::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHRTVIADQPICPLKFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMES 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ 790 800 810 820 830 840 840 850 860 870 pF1KSD ELLP-SGFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS : : :: XP_006 EGLTWEGFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQ 850 860 870 880 890 900 >>XP_016870428 (OMIM: 609471,614409) PREDICTED: non-lyso (855 aa) initn: 4450 init1: 4450 opt: 4461 Z-score: 5262.7 bits: 984.9 E(85289): 0 Smith-Waterman score: 5949; 97.5% identity (97.5% similar) in 877 aa overlap (1-877:1-855) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK ::::::::::::::::::::::::::: ::::::::::: XP_016 EPWLRVNAYLIHDTADWKDLNLKFVLQ----------------------AVMESEMKFDK 610 620 630 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG 760 770 780 790 800 810 850 860 870 pF1KSD FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS ::::::::::::::::::::::::::::::::::::: XP_016 FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS 820 830 840 850 >>XP_016870426 (OMIM: 609471,614409) PREDICTED: non-lyso (905 aa) initn: 4450 init1: 4450 opt: 4461 Z-score: 5262.4 bits: 984.9 E(85289): 0 Smith-Waterman score: 5668; 96.9% identity (96.9% similar) in 842 aa overlap (1-841:1-820) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK ::::::::::::::::::::::::::: ::::::::::: XP_016 EPWLRVNAYLIHDTADWKDLNLKFVLQ----------------------AVMESEMKFDK 610 620 630 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 700 710 720 730 740 750 790 800 810 820 830 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLP-S ::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWE 760 770 780 790 800 810 840 850 860 870 pF1KSD GFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS :: XP_016 GFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKASW 820 830 840 850 860 870 >>XP_005251583 (OMIM: 609471,614409) PREDICTED: non-lyso (911 aa) initn: 3074 init1: 3074 opt: 4439 Z-score: 5236.3 bits: 980.1 E(85289): 0 Smith-Waterman score: 5646; 96.2% identity (96.2% similar) in 848 aa overlap (1-841:1-826) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 pF1KSD QHRTVIADQ------FTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR ::::::::: ::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHRTVIADQPICPLKFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGGGDDAPGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDSTGQQVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDM 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRIMFGAKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WYKSALFNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTYDVHFYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMES ::::::::::::::::::::::::::::::::: ::::: XP_005 IGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQ----------------------AVMES 610 620 630 660 670 680 690 700 710 pF1KSD EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDK 640 650 660 670 680 690 720 730 740 750 760 770 pF1KSD FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFP 700 710 720 730 740 750 780 790 800 810 820 830 pF1KSD TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQHVVRALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQ 760 770 780 790 800 810 840 850 860 870 pF1KSD ELLP-SGFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS : : :: XP_005 EGLTWEGFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQ 820 830 840 850 860 870 >>XP_016870430 (OMIM: 609471,614409) PREDICTED: non-lyso (804 aa) initn: 4270 init1: 4270 opt: 4273 Z-score: 5041.0 bits: 943.8 E(85289): 0 Smith-Waterman score: 5485; 91.7% identity (91.7% similar) in 877 aa overlap (1-877:1-804) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ ::::::::: XP_016 QHRTVIADQ--------------------------------------------------- 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::: XP_016 ----------------------DSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 190 200 210 220 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 290 300 310 320 330 340 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 350 360 370 380 390 400 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 410 420 430 440 450 460 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 470 480 490 500 510 520 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 530 540 550 560 570 580 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 590 600 610 620 630 640 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 650 660 670 680 690 700 790 800 810 820 830 840 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLPSG 710 720 730 740 750 760 850 860 870 pF1KSD FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS ::::::::::::::::::::::::::::::::::::: XP_016 FCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS 770 780 790 800 >>XP_016870429 (OMIM: 609471,614409) PREDICTED: non-lyso (854 aa) initn: 3987 init1: 3987 opt: 3992 Z-score: 4708.8 bits: 882.4 E(85289): 0 Smith-Waterman score: 5204; 90.9% identity (90.9% similar) in 842 aa overlap (1-841:1-769) 10 20 30 40 50 60 pF1KSD MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTQDPGNMGTGVPASEQISCAKEDPQVYCPEETGGTKDVQVTDCKSPEDSRPPKETDCC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPEDSGQLMVSYEGKAMGYQVPPFGWRICLAHEFTEKRKPFQANNVSLSNMIKHIGMGLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQWWYRKTHVEKKTPFIDMINSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHRTVIADQFTVCLRREGQTVYQQVLSLERPSVLRSWNWGLCGYFAFYHALYPRAWTVYQ ::::::::: XP_016 QHRTVIADQ--------------------------------------------------- 250 260 270 280 290 300 pF1KSD LPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD :::::::::::::::::::::::::::::::::::::: XP_016 ----------------------DSSLPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDD 190 200 210 220 310 320 330 340 350 360 pF1KSD APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APGGLWNEPFCLERSGETVRGLLLHHPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQ 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVWQDLLQDGQLDSPTGQSTPTQKGVGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFG 290 300 310 320 330 340 430 440 450 460 470 480 pF1KSD AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKGQVHYRRYTRFFGQDGDAAPALSHYALCRYAEWEERISAWQSPVLDDRSLPAWYKSAL 350 360 370 380 390 400 490 500 510 520 530 540 pF1KSD FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNELYFLADGGTVWLEVLEDSLPEELGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVH 410 420 430 440 450 460 550 560 570 580 590 600 pF1KSD FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYASFALIMLWPKLELSLQYDMALATLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDD 470 480 490 500 510 520 610 620 630 640 650 660 pF1KSD EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDK 530 540 550 560 570 580 670 680 690 700 710 720 pF1KSD DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILS 590 600 610 620 630 640 730 740 750 760 770 780 pF1KSD RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVR 650 660 670 680 690 700 790 800 810 820 830 pF1KSD ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQELLP-S ::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 ALQTIFELNVQAFAGGAMGAVNGMQPHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWE 710 720 730 740 750 760 840 850 860 870 pF1KSD GFCLWVIVISSTCWELLEGKDSTASIYPVEVALQRVPS :: XP_016 GFQTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKASW 770 780 790 800 810 820 >>XP_016870434 (OMIM: 609471,614409) PREDICTED: non-lyso (742 aa) initn: 3972 init1: 3972 opt: 3980 Z-score: 4695.4 bits: 879.7 E(85289): 0 Smith-Waterman score: 3980; 95.6% identity (96.9% similar) in 607 aa overlap (242-841:52-657) 220 230 240 250 260 pF1KSD SVLRSWNWGLCGYFAFYHALYPRAWTVYQLPGQNVTLTCRQITP---ILPHD---YQDSS :: .... : ..: . : . :: XP_016 SCPWSAQVSSAAGTGACVGTLLSTMPSIPEPGLSISFLAR-MSPSPAVRSHPSCPMTTSS 30 40 50 60 70 80 270 280 290 300 310 320 pF1KSD LPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDDAPGGLWNEPFCLERSGETVRGLLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVGVFVWDVENEGDEALDVSIMFSMRNGLGGGDDAPGGLWNEPFCLERSGETVRGLLLH 90 100 110 120 130 140 330 340 350 360 370 380 pF1KSD HPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQQVWQDLLQDGQLDSPTGQSTPTQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPTLPNPYTMAVAARVTAATTVTHITAFDPDSTGQQVWQDLLQDGQLDSPTGQSTPTQKG 150 160 170 180 190 200 390 400 410 420 430 440 pF1KSD VGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFGAKGQVHYRRYTRFFGQDGDAAPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGIAGAVCVSSKLRPRGQCRLEFSLAWDMPRIMFGAKGQVHYRRYTRFFGQDGDAAPALS 210 220 230 240 250 260 450 460 470 480 490 500 pF1KSD HYALCRYAEWEERISAWQSPVLDDRSLPAWYKSALFNELYFLADGGTVWLEVLEDSLPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYALCRYAEWEERISAWQSPVLDDRSLPAWYKSALFNELYFLADGGTVWLEVLEDSLPEE 270 280 290 300 310 320 510 520 530 540 550 560 pF1KSD LGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVHFYASFALIMLWPKLELSLQYDMALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRNMCHLRPTLRDYGRFGYLEGQEYRMYNTYDVHFYASFALIMLWPKLELSLQYDMALA 330 340 350 360 370 380 570 580 590 600 610 620 pF1KSD TLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLREDLTRRRYLMSGVMAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFV 390 400 410 420 430 440 630 640 650 660 670 680 pF1KSD LQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDKDHDGLIENGGYADQTYDGWVTTGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDKDHDGLIENGGYADQTYDGWVTTGPS 450 460 470 480 490 500 690 700 710 720 730 740 pF1KSD AYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILSRGQEAYERLLWNGRYYNYDSSSRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILSRGQEAYERLLWNGRYYNYDSSSRPQ 510 520 530 540 550 560 750 760 770 780 790 800 pF1KSD SRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVRALQTIFELNVQAFAGGAMGAVNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSVMSDQCAGQWFLKACGLGEGDTEVFPTQHVVRALQTIFELNVQAFAGGAMGAVNGMQ 570 580 590 600 610 620 810 820 830 840 850 860 pF1KSD PHGVPDKSSVQSDEVWVGVVYGLAATMIQELLP-SGFCLWVIVISSTCWELLEGKDSTAS :::::::::::::::::::::::::::::: : :: XP_016 PHGVPDKSSVQSDEVWVGVVYGLAATMIQEGLTWEGFQTAEGCYRTVWERLGLAFQTPEA 630 640 650 660 670 680 870 pF1KSD IYPVEVALQRVPS XP_016 YCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKASWPKVKQGTGLRTGPMFGPKEAMANLS 690 700 710 720 730 740 877 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:47:18 2016 done: Thu Nov 3 06:47:20 2016 Total Scan time: 11.500 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]