FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1612, 542 aa 1>>>pF1KSDA1612 542 - 542 aa - 542 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1754+/-0.000352; mu= 15.4543+/- 0.022 mean_var=96.4272+/-20.085, 0's: 0 Z-trim(117.2): 8 B-trim: 1753 in 2/49 Lambda= 0.130609 statistics sampled from 28971 (28979) to 28971 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.34), width: 16 Scan time: 10.790 The best scores are: opt bits E(85289) NP_060703 (OMIM: 615857) prolyl 3-hydroxylase OGFO ( 542) 3707 708.8 1.1e-203 NP_001311286 (OMIM: 615857) prolyl 3-hydroxylase O ( 541) 3689 705.4 1.1e-202 NP_001311287 (OMIM: 615857) prolyl 3-hydroxylase O ( 487) 3346 640.8 2.9e-183 NP_001311290 (OMIM: 615857) prolyl 3-hydroxylase O ( 487) 3346 640.8 2.9e-183 NP_001311289 (OMIM: 615857) prolyl 3-hydroxylase O ( 445) 3028 580.8 2.9e-165 NP_001311288 (OMIM: 615857) prolyl 3-hydroxylase O ( 445) 3028 580.8 2.9e-165 NP_001311291 (OMIM: 615857) prolyl 3-hydroxylase O ( 402) 2767 531.6 1.7e-150 NP_001311292 (OMIM: 615857) prolyl 3-hydroxylase O ( 504) 1804 350.2 8.7e-96 >>NP_060703 (OMIM: 615857) prolyl 3-hydroxylase OGFOD1 i (542 aa) initn: 3707 init1: 3707 opt: 3707 Z-score: 3778.1 bits: 708.8 E(85289): 1.1e-203 Smith-Waterman score: 3707; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542) 10 20 30 40 50 60 pF1KSD MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY 490 500 510 520 530 540 pF1KSD YE :: NP_060 YE >>NP_001311286 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (541 aa) initn: 3361 init1: 3361 opt: 3689 Z-score: 3759.8 bits: 705.4 E(85289): 1.1e-202 Smith-Waterman score: 3689; 99.8% identity (99.8% similar) in 542 aa overlap (1-542:1-541) 10 20 30 40 50 60 pF1KSD MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDP ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSH-VIVMDMDP 10 20 30 40 50 70 80 90 100 110 120 pF1KSD FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD SLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLK 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY 480 490 500 510 520 530 pF1KSD YE :: NP_001 YE 540 >>NP_001311287 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (487 aa) initn: 3346 init1: 3346 opt: 3346 Z-score: 3411.2 bits: 640.8 E(85289): 2.9e-183 Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 487 aa overlap (56-542:1-487) 30 40 50 60 70 80 pF1KSD FSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMN :::::::::::::::::::::::::::::: NP_001 MDMDPFLHCVIPNFIQSQDFLEGLQKELMN 10 20 30 90 100 110 120 130 140 pF1KSD LDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD YEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWN 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD KLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEI 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD LYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD KRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETT 280 290 300 310 320 330 390 400 410 420 430 440 pF1KSD DITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTG 340 350 360 370 380 390 450 460 470 480 490 500 pF1KSD HYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYR 400 410 420 430 440 450 510 520 530 540 pF1KSD DRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE ::::::::::::::::::::::::::::::::::::: NP_001 DRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE 460 470 480 >>NP_001311290 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (487 aa) initn: 3346 init1: 3346 opt: 3346 Z-score: 3411.2 bits: 640.8 E(85289): 2.9e-183 Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 487 aa overlap (56-542:1-487) 30 40 50 60 70 80 pF1KSD FSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMN :::::::::::::::::::::::::::::: NP_001 MDMDPFLHCVIPNFIQSQDFLEGLQKELMN 10 20 30 90 100 110 120 130 140 pF1KSD LDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD YEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWN 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD KLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEI 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD LYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD KRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETT 280 290 300 310 320 330 390 400 410 420 430 440 pF1KSD DITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTG 340 350 360 370 380 390 450 460 470 480 490 500 pF1KSD HYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYR 400 410 420 430 440 450 510 520 530 540 pF1KSD DRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE ::::::::::::::::::::::::::::::::::::: NP_001 DRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE 460 470 480 >>NP_001311289 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (445 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 3087.9 bits: 580.8 E(85289): 2.9e-165 Smith-Waterman score: 3028; 99.8% identity (100.0% similar) in 443 aa overlap (100-542:3-445) 70 80 90 100 110 120 pF1KSD IQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSD .::::::::::::::::::::::::::::: NP_001 MIKSDDLKKRREPHISTLRKILFEDFRSWLSD 10 20 30 130 140 150 160 170 180 pF1KSD ISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDE 40 50 60 70 80 90 190 200 210 220 230 240 pF1KSD HFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYF 100 110 120 130 140 150 250 260 270 280 290 300 pF1KSD EPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCE 160 170 180 190 200 210 310 320 330 340 350 360 pF1KSD ALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLA 220 230 240 250 260 270 370 380 390 400 410 420 pF1KSD PSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKE 280 290 300 310 320 330 430 440 450 460 470 480 pF1KSD SSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEE 340 350 360 370 380 390 490 500 510 520 530 540 pF1KSD LLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE 400 410 420 430 440 >>NP_001311288 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (445 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 3087.9 bits: 580.8 E(85289): 2.9e-165 Smith-Waterman score: 3028; 99.8% identity (100.0% similar) in 443 aa overlap (100-542:3-445) 70 80 90 100 110 120 pF1KSD IQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSD .::::::::::::::::::::::::::::: NP_001 MIKSDDLKKRREPHISTLRKILFEDFRSWLSD 10 20 30 130 140 150 160 170 180 pF1KSD ISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDE 40 50 60 70 80 90 190 200 210 220 230 240 pF1KSD HFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYF 100 110 120 130 140 150 250 260 270 280 290 300 pF1KSD EPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCE 160 170 180 190 200 210 310 320 330 340 350 360 pF1KSD ALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLA 220 230 240 250 260 270 370 380 390 400 410 420 pF1KSD PSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKE 280 290 300 310 320 330 430 440 450 460 470 480 pF1KSD SSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEE 340 350 360 370 380 390 490 500 510 520 530 540 pF1KSD LLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE 400 410 420 430 440 >>NP_001311291 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (402 aa) initn: 2767 init1: 2767 opt: 2767 Z-score: 2822.8 bits: 531.6 E(85289): 1.7e-150 Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 402 aa overlap (141-542:1-402) 120 130 140 150 160 170 pF1KSD HISTLRKILFEDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYL :::::::::::::::::::::::::::::: NP_001 MSCAKYEFTDALLCHDDELEGRRIAFILYL 10 20 30 180 190 200 210 220 230 pF1KSD VPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSR 40 50 60 70 80 90 240 250 260 270 280 290 pF1KSD LSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEES 100 110 120 130 140 150 300 310 320 330 340 350 pF1KSD SEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRS 160 170 180 190 200 210 360 370 380 390 400 410 pF1KSD EALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNS 220 230 240 250 260 270 420 430 440 450 460 470 pF1KSD QQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEG 280 290 300 310 320 330 480 490 500 510 520 530 pF1KSD WEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNR 340 350 360 370 380 390 540 pF1KSD TGFWDFSFIYYE :::::::::::: NP_001 TGFWDFSFIYYE 400 >>NP_001311292 (OMIM: 615857) prolyl 3-hydroxylase OGFOD (504 aa) initn: 1831 init1: 1804 opt: 1804 Z-score: 1840.7 bits: 350.2 E(85289): 8.7e-96 Smith-Waterman score: 3368; 93.0% identity (93.0% similar) in 542 aa overlap (1-542:1-504) 10 20 30 40 50 60 pF1KSD MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLK :::::::::::::::::::::: NP_001 SLTRPPNYFEPPIPRSPHIPQD-------------------------------------- 250 260 310 320 330 340 350 360 pF1KSD PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNF 270 280 290 300 310 320 370 380 390 400 410 420 pF1KSD TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPE 330 340 350 360 370 380 430 440 450 460 470 480 pF1KSD PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTS 390 400 410 420 430 440 490 500 510 520 530 540 pF1KSD YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIY 450 460 470 480 490 500 pF1KSD YE :: NP_001 YE 542 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:48:56 2016 done: Thu Nov 3 06:48:57 2016 Total Scan time: 10.790 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]