Result of FASTA (ccds) for
pF1KSDA1686
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1686, 1174 aa
1>>>pF1KSDA1686 1174 - 1174 aa - 1174 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8365+/-0.00128; mu= 0.0408+/- 0.076
mean_var=196.9259+/-40.353, 0's: 0 Z-trim(106.8): 75 B-trim: 16 in 2/50
Lambda= 0.091395
statistics sampled from 9129 (9190) to 9129 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.282), width: 16
Scan time: 4.560
The best scores are: opt bits E(32554)
CCDS44840.2 PLEKHA5 gene_id:54477|Hs108|chr12 (1174) 7768 1038.1 0
CCDS58213.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1282) 4546 613.3 1.2e-174
CCDS8682.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1116) 4169 563.6 9.5e-160
CCDS58214.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1098) 3421 464.9 4.6e-130
CCDS31434.1 PLEKHA7 gene_id:144100|Hs108|chr11 (1121) 1231 176.2 3.9e-43
CCDS1444.1 PLEKHA6 gene_id:22874|Hs108|chr1 (1048) 619 95.5 7.2e-19
CCDS55809.1 PLEKHA5 gene_id:54477|Hs108|chr12 ( 76) 523 82.4 4.4e-16
CCDS54291.1 PLEKHA4 gene_id:57664|Hs108|chr19 ( 583) 489 78.3 6.2e-14
CCDS12737.1 PLEKHA4 gene_id:57664|Hs108|chr19 ( 779) 489 78.3 8e-14
>>CCDS44840.2 PLEKHA5 gene_id:54477|Hs108|chr12 (1174 aa)
initn: 7768 init1: 7768 opt: 7768 Z-score: 5545.8 bits: 1038.1 E(32554): 0
Smith-Waterman score: 7768; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KSD TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::
CCDS44 TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1150 1160 1170
>>CCDS58213.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1282 aa)
initn: 5113 init1: 2651 opt: 4546 Z-score: 3249.2 bits: 613.3 E(32554): 1.2e-174
Smith-Waterman score: 7060; 91.1% identity (91.1% similar) in 1212 aa overlap (1-1104:1-1212)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKR------VDKITSENAPTKETNNIP
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::
CCDS58 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRITFNFRVDKITSENAPTKETNNIP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD NHRVLIKPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NHRVLIKPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD EQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD VTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNIS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD DQTMHSIPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DQTMHSIPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD RSVPAGLTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RSVPAGLTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSP
610 620 630 640 650 660
660 670
pF1KSD KNEILSHHLQRNTIYLDHQ---------------------------------------LS
::::::::::::::::::: ::
CCDS58 KNEILSHHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKSKISLYCLS
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD QDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 QDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEI
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD EMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQ
790 800 810 820 830 840
800 810 820 830 840 850
pF1KSD EQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKY
850 860 870 880 890 900
pF1KSD KNE---------------------------------------------------------
:::
CCDS58 KNEEEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYP
910 920 930 940 950 960
860 870 880 890 900 910
pF1KSD ------GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAK
970 980 990 1000 1010 1020
920 930 940 950 960 970
pF1KSD SPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQ
1030 1040 1050 1060 1070 1080
980 990 1000 1010 1020 1030
pF1KSD ACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHET
1090 1100 1110 1120 1130 1140
1040 1050 1060 1070 1080 1090
pF1KSD PATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDV
1150 1160 1170 1180 1190 1200
1100 1110 1120 1130 1140 1150
pF1KSD TFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPE
::::::::::::
CCDS58 TFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPE
1210 1220 1230 1240 1250 1260
>--
initn: 462 init1: 462 opt: 462 Z-score: 338.9 bits: 74.8 E(32554): 1.5e-12
Smith-Waterman score: 462; 100.0% identity (100.0% similar) in 70 aa overlap (1105-1174:1213-1282)
1080 1090 1100 1110 1120 1130
pF1KSD SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
::::::::::::::::::::::::::::::
CCDS58 SVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPE
1190 1200 1210 1220 1230 1240
1140 1150 1160 1170
pF1KSD VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::::::::
CCDS58 VSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1250 1260 1270 1280
>>CCDS8682.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1116 aa)
initn: 7388 init1: 4142 opt: 4169 Z-score: 2981.5 bits: 563.6 E(32554): 9.5e-160
Smith-Waterman score: 7276; 95.1% identity (95.1% similar) in 1174 aa overlap (1-1174:1-1116)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 PNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 KPEIQNNQKNKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 AQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 QKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 DKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 IPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILS
:::::::::::::::
CCDS86 LTLQSVSPQSLQGKT---------------------------------------------
610
670 680 690 700 710 720
pF1KSD HHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 -------------LSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKE
620 630 640 650 660
730 740 750 760 770 780
pF1KSD KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 KYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREY
670 680 690 700 710 720
790 800 810 820 830 840
pF1KSD DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 DKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTT
730 740 750 760 770 780
850 860 870 880 890 900
pF1KSD EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 EIGMIGSKPFSTVKYKNEGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGS
790 800 810 820 830 840
910 920 930 940 950 960
pF1KSD HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 HFPVGVVPPRAKSPTPESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTV
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KSD EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 EEQMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTA
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KSD IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 IRENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMD
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KSD KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 KERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQ
1030 1040 1050 1060 1070 1080
1150 1160 1170
pF1KSD TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
::::::::::::::::::::::::::::::::::
CCDS86 TMAVKSLSPSPESSASPVPSTQPQLTEGSHFMCV
1090 1100 1110
>>CCDS58214.1 PLEKHA5 gene_id:54477|Hs108|chr12 (1098 aa)
initn: 6642 init1: 3400 opt: 3421 Z-score: 2448.6 bits: 464.9 E(32554): 4.6e-130
Smith-Waterman score: 6471; 90.1% identity (90.9% similar) in 1129 aa overlap (109-1174:1-1098)
80 90 100 110 120 130
pF1KSD ERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPISMINEASNYNVTSDYAVHP
::::::::::::::::::::::::::::::
CCDS58 MTSEEKKERPISMINEASNYNVTSDYAVHP
10 20 30
140 150 160 170 180 190
pF1KSD MSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLC
40 50 60 70 80 90
200 210 220 230 240 250
pF1KSD LFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMEL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KSD WMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 WMKAMLDAALVQTEPVKRVDKITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIEE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KSD KKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACPAQTVHYRPINLSSSENKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KKALEAEKYGFQKDGQDRPLTKINSVKLNSLPSEYESGSACPAQTVHYRPINLSSSENKI
220 230 240 250 260 270
380 390 400 410 420 430
pF1KSD VNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKIQKGRGHEEETRGVISYQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKIQKGRGHEEETRGVISYQT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KSD LPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTHDKTLGPGAEEKRRSMRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTHDKTLGPGAEEKRRSMRDD
340 350 360 370 380 390
500 510 520 530 540 550
pF1KSD TMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHSIPTSPSHGSIAAYQGYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHSIPTSPSHGSIAAYQGYSP
400 410 420 430 440 450
560 570 580 590 600 610
pF1KSD QRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAGLTLQSVSPQSLQGKTPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
CCDS58 QRTYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAGLTLQSVSPQSLQGKTMKE
460 470 480 490 500 510
620 630 640 650 660 670
pF1KSD LTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQLSQDE
. .: . . . : :..: ::.: ::::::
CCDS58 -NEPIITMVHTMIENSALR----PQLYQ--------------------------QLSQDE
520 530
680 690 700 710 720 730
pF1KSD GRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMH
540 550 560 570 580 590
740 750 760 770 780 790
pF1KSD ADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQL
600 610 620 630 640 650
800 810 820 830 840 850
pF1KSD DHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE
660 670 680 690 700 710
pF1KSD ------------------------------------------------------------
CCDS58 EEEVVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKMYQVQGYPRNG
720 730 740 750 760 770
860 870 880 890 900 910
pF1KSD ---GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPT
780 790 800 810 820 830
920 930 940 950 960 970
pF1KSD PESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PESSTIASYVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACL
840 850 860 870 880 890
980 990 1000 1010 1020 1030
pF1KSD REKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 REKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPAT
900 910 920 930 940 950
1040 1050 1060 1070 1080 1090
pF1KSD EIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKERNKDKMPEDVTFS
960 970 980 990 1000 1010
1100 1110 1120 1130 1140 1150
pF1KSD PQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PQDETQTANHKPEEHPEENTKNSVDEQEETVISYESTPEVSRGNQTMAVKSLSPSPESSA
1020 1030 1040 1050 1060 1070
1160 1170
pF1KSD SPVPSTQPQLTEGSHFMCV
:::::::::::::::::::
CCDS58 SPVPSTQPQLTEGSHFMCV
1080 1090
>>CCDS31434.1 PLEKHA7 gene_id:144100|Hs108|chr11 (1121 aa)
initn: 1544 init1: 481 opt: 1231 Z-score: 887.8 bits: 176.2 E(32554): 3.9e-43
Smith-Waterman score: 1557; 32.3% identity (56.0% similar) in 1167 aa overlap (11-999:10-1109)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
.::. :.::. : :::::::.. . :::::: ::: : .:: .: :::
CCDS31 MAAATVGRDTLPEHWSYGVCRDGRVFFINDQLRCTTWLHPRTGEPVNSGHMIRS-DLPR
10 20 30 40 50
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::..: ::: :.:.::.. .. .:::::: : .: :...:. :.......:: :
CCDS31 GWEEGFTEEGASYFIDHNQQTTAFRHPVTGQFSPENSEFILQEEPNPHMSKQDRNQRPSS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD MINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQD
:..:.:. ...: ..: .: . ..:.:::.::::...:.::::.::: ::::.:::
CCDS31 MVSETSTAGTASTLEAKP-GP--KIIKSSSKVHSFGKRDQAIRRNPNVPVVVRGWLHKQD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD STGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAH
:.::.:::.:::::.: :::::.: .::..:::: :::. :. .. ::.:.:::.:::.:
CCDS31 SSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVH
180 190 200 210 220 230
250 260 270
pF1KSD PNMR-------------------TYYFCTDTGKEMELWMKAMLDAALVQTEP-VKR-VDK
.:: :::: .:: ..:. :..:: .:: : .. .:: ..:
CCDS31 TGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQAAQVLSRSSLKRDMEK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KSD ITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIE--EKKALEAEKYGFQKDGQDRP
. . .: . .. .. . : . .. . : :.. :.:.: :.: :
CCDS31 VERQAVPQANHTESCHECGRVGPGHTRDCPHRGHDDIVNFERQEQEGEQYRSQRD----P
300 310 320 330 340 350
340 350 360 370 380 390
pF1KSD LT-KINSVKLNSLPSEYESGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTG-
: : . : : : : . . : . . .. . .. :. :.. .::
CCDS31 LEGKRDRSKARSPYSPAEEDALFMDLPTGPRGQQAQPQRAEKNGMLPASYGPGEQNGTGG
360 370 380 390 400 410
400 410 420 430 440 450
pF1KSD -----PLYTEADRVIQRTNSMQQLEQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQI
: :. .. :: ... :.:.: . ::: ..:.. :::::. :.. .
CCDS31 YQRAFPPRTNPEKHSQRKSNLAQVEHWARAQKG-----DSRSLPLDQTLPRQGPGQSLS-
420 430 440 450 460
460 470 480 490 500
pF1KSD MARYPEGYRTLPRNSK-------TRPESICSVTPSTHDKT--LGPGAEEKRRSMRDDTMW
.::.:.:::.... :... : ..:.. : ..:: ::. :: :.:
CCDS31 ---FPENYQTLPKSTRHPSGGSSPPPRNLPSDYKYAQDRASHLKMSSEE-RRAHRDGTVW
470 480 490 500 510 520
510 520 530 540 550
pF1KSD QLYEWQQRQ-FYNKQSTLPRHSTLSSPKTMVNISDQTMHSIPTS----PSHGSI---AAY
::::::::: : . . : : :.::. . ...: .: : :: ..: .
CCDS31 QLYEWQQRQQFRHGSPTAP--ICLGSPEFTDQGRSRSMLEVPRSISVPPSPSDIPPPGPP
530 540 550 560 570
560 570 580 590 600
pF1KSD QGYSPQRTY----RSEVSSPIQRGDVTID-----RRHRAHHPKHVYVPDRRSVPA-GLTL
. . :.: . : :. : :: .: :. :: :.: :. ::::.:. :
CCDS31 RVFPPRRPHTPAERVTVKPPDQRRSVDISLGDSPRRARGHAVKNSSHVDRRSMPSMGYMT
580 590 600 610 620 630
610 620 630 640 650 660
pF1KSD QSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILSHHL
..:: ::.::. .. : : : .: . ..::. ...
CCDS31 HTVSAPSLHGKSADDTYLQLKK------DL---------EYLDLKMTGRD----------
640 650 660 670
670 680 690 700 710 720
pF1KSD QRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYT
: .:. .: . : : :.::: .::::.:.. ::.:.. :...:
CCDS31 ----------LLKDR---SLKPVKIAESDTDVKLSIFCEQDRVLQDLEDKIRALKENKDQ
680 690 700 710 720
730 740 750 760 770 780
pF1KSD LEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKL
::..: ...:.. :.: .. .. :. ::. :. :::: ..:.: :: :: ::
CCDS31 LESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEMENAWNEYLKL
730 740 750 760 770 780
790 800 810 820 830
pF1KSD EYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQ--------
: :: .. .::: . : ...::::.::::.:: ::: .:.
CCDS31 ENDVEQLKQTLQEQHRRAFFFQ------EKSQIQKDLWRIEDVTAGLSANKENFRILVES
790 800 810 820 830
840 850
pF1KSD ----QRGTTEI---------GMIGSKP-------------------F----STVKYKNEG
.: :. . . ::: : . : :. .
CCDS31 VKNPERKTVPLFPHPPVPSLSTSESKPPPQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHP
840 850 860 870 880 890
860 870
pF1KSD PDYR----------------------------LYKSE------PELTTVAEV--------
:. : ::. : : : : .
CCDS31 PQLRKVTSPLQSPTKAKPKVEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRG
900 910 920 930 940 950
880 890 900 910
pF1KSD -----DES----------NGEEKSE---PVSEIETSVVKG--SHFPVGVVPPRAKSPT-P
:: ::. . : ::: : ....: .. .:.: :... : :
CCDS31 LKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSLGLVGPESRYQTLP
960 970 980 990 1000 1010
920 930 940 950 960
pF1KSD ------------ESSTIASYVTLRKTKKMMDLRTE--RPRSAVEQLCLAESTRPRMTVEE
.::::: :::::. . . .. ::.::.:.: .. : .:..::
CCDS31 GRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEE
1020 1030 1040 1050 1060 1070
970 980 990 1000 1010 1020
pF1KSD QMERIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIR
:.::..:::.: .::.:. : : .... : : :
CCDS31 QLERMKRHQKALVRERKRTL---GQGERTGLPSSRYLSRPLPGDLGSVC
1080 1090 1100 1110 1120
1030 1040 1050 1060 1070 1080
pF1KSD ENDVKPDHETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEPNGVNSVEMMDKE
>>CCDS1444.1 PLEKHA6 gene_id:22874|Hs108|chr1 (1048 aa)
initn: 1163 init1: 511 opt: 619 Z-score: 452.2 bits: 95.5 E(32554): 7.2e-19
Smith-Waterman score: 1482; 31.1% identity (57.1% similar) in 1141 aa overlap (109-1167:1-1035)
80 90 100 110 120 130
pF1KSD ERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPISMINEASNYNVTSDYAVHP
:... .:: . .. :.:..:. : :
CCDS14 MSNKTGGKRPATTNSDIPNHNMVSE--VPP
10 20
140 150 160 170 180 190
pF1KSD MSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLC
: :..:...:. :::::.:.::::::::.. :::.:: :.:.: :.:::::: : :
CCDS14 ERPSVRATRTARKAVAFGKRSHSMKRNPNAPVTKAGWLFKQASSGVKQWNKRWFVLVDRC
30 40 50 60 70 80
200 210 220 230 240 250
pF1KSD LFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMEL
::::.:::::.::::: : ::..: . :.:.::..::: : ..:::.: ... .:.:
CCDS14 LFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTYFFSAESPEEQEA
90 100 110 120 130 140
260 270 280 290 300
pF1KSD WMKAMLDAALVQTEPVKRV---------DKITSENAPTKETNNIPNHRVLIKPEIQNNQK
:..:: .:: :: :... .: :::.: .. .. : : : ::: . . .
CCDS14 WIQAMGEAARVQIPPAQKSVPQAVRHSHEKPDSENVPPSKHHQQPPHNSLPKPEPEAKTR
150 160 170 180 190 200
310 320 330 340 350
pF1KSD NKEMSKIEEKKALEAEKYGFQKDGQDRPLTKINSVKLNSLP-----SEYE------SGSA
.. .. :: ::. . . . .: .: :.. . : : : .:.
CCDS14 GEGDGRGCEK----AERRPERPEVKKEPPVKANGLPAGPEPASEPGSPYPEGPRVPGGGE
210 220 230 240 250 260
360 370 380 390 400 410
pF1KSD CPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWI
::: .. . : .. . : ::.: . : :. :.. :: .::.::.::.
CCDS14 QPAQPNGWQ-YHSPSRPGSTAFPSQDGETGGHRRSFPP-RTNPDKIAQRKSSMNQLQQWV
270 280 290 300 310 320
420 430 440 450 460 470
pF1KSD KIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPS
....: :. :. . . : .: . . ..::. :. : . .:::::::. :.
CCDS14 NLRRGVPPPEDLRSPSRFYPVSRRVPEYYGPYSSQYPDDYQYYPPG--VRPESICSM-PA
330 340 350 360 370
480 490 500 510 520
pF1KSD THDKTLGPGA-EEKRRSMRDD--TMWQLYEWQQRQFYNKQST---LPRHSTL--------
.:. : : :.::...:. .:: ::.. :..:.. .: :
CCDS14 -YDRISPPWALEDKRHAFRNGGGPAYQLREWKEPASYGRQDATVWIPSPSRQPVYYDELD
380 390 400 410 420 430
530 540 550 560 570 580
pF1KSD SSPKTMVNISDQTM-HSIPTSPSHGSIAAYQGYSPQRTYRSEVSSPIQRGDVTIDRRHRA
.. ... .: : ::.: :::.:: :: : : : : :: : . : .
CCDS14 AASSSLRRLSLQPRSHSVPRSPSQGS------YSRARIY-SPVRSPSARFERLPPRSEDI
440 450 460 470 480 490
590 600 610 620 630 640
pF1KSD HHPKHVYVPDRRSVPAGLTLQSVSPQSLQGKTPEELTLLLIKLRRQQAELSSIREHTLAQ
. .:: :::. :: :.:
CCDS14 YADPAAYVM-RRSIS--------SP-----KVP---------------------------
500 510
650 660 670 680 690 700
pF1KSD LMQLKLEAHSPKNEILSHHLQRNTIYLDHQLSQDEGRGTLYKYRPEEVDIDAKLSRLCEQ
: :.. : .:. :. .: : : :..::::
CCDS14 ----------PYPEVF--------------------RDSLHTYKLNEQDTDKLLGKLCEQ
520 530 540
710 720 730 740 750 760
pF1KSD DKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTC
.:::. .. .:::. :: .::.::... ::.:: ...:: . . ..:.::: :..
CCDS14 NKVVREQDRLVQQLRAEKESLESALMGTHQELEMFGSQPAYPEKLRHKKDSLQNQLINIR
550 560 570 580 590 600
770 780 790 800 810 820
pF1KSD RELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRI
:::.::. : . ::..:: .:.. .... :::. ..:.. ..: :::::.:::
CCDS14 VELSQATTALTNSTIEYEHLESEVSALHDDLWEQLN----LDTQNEVLNR-QIQKEIWRI
610 620 630 640 650
830 840 850
pF1KSD QDVMEGLSKHKQQRGTTEI---GMIGSK----------------------PFSTVKYKNE
::::::: :.. .::: : .: . ::: :. ..
CCDS14 QDVMEGLRKNNPSRGTDTAKHRGGLGPSATYSSNSPASPLSSASLTSPLSPFSLVSGSQG
660 670 680 690 700 710
860 870 880 890 900
pF1KSD GP----------DYRLYKSEPELTTVAEV--DESNGEEKSEPVSEIETSVVKGSHFPVGV
.: .:. :..:. : .. : : ..: .: .... : :::
CCDS14 SPTKPGSNEPKANYEQSKKDPHQTLPLDTPRDISLVPTRQEVEAEKQAALNK-----VGV
720 730 740 750 760 770
910 920 930 940 950 960
pF1KSD VPPRAKSPTPESSTIASYVTLRKTKKMMDLRT-ERPRSAVEQLCLAESTRPRMTVEEQME
::::.:::: . : .. : . : . :::.::: . . .:.::::..
CCDS14 VPPRTKSPTDDEVTPSAVVRRNASGLTNGLSSQERPKSAV----FPGEGKVKMSVEEQID
780 790 800 810 820
970 980 990 1000 1010 1020
pF1KSD RIRRHQQACLREKKKGLNVIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIR-EN
:.::::.. .:::...:.. .. .: :: : . .. : ..:..:.: :.
CCDS14 RMRRHQSGSMREKRRSLQL--PASPAPDPSPRPAYKVVRRHRSIHEVDISNLEAALRAEE
830 840 850 860 870 880
1030 1040 1050 1060 1070
pF1KSD DVKPDHETPATEIVQLK--ETEPQ--NVDFSKELKKTENISY-EMLFEPEPNG-VNSVEM
.::: ::..:. : ::: .::..:::. ... : .. ::. .. :.
CCDS14 PGGHAYETPREEIARLRKMELEPQHYDVDINKELSTPDKVLIPERYIDLEPDTPLSPEEL
890 900 910 920 930 940
1080 1090 1100 1110 1120 1130
pF1KSD MDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEETV-ISYESTPEVSR
.:... ... .. : .... .. ........:::. . :: . :.::
CCDS14 KEKQKKVERIKTLIAKSSMQNVVPIGEGDSVDVPQDSESQLQEQEKRIEISCALATEASR
950 960 970 980 990 1000
1140 1150 1160 1170
pF1KSD GNQTMAVKSLSPSPESS-ASPVPSTQPQLTEGSHFMCV
.. ..:. .::: .: :::.: ..: .:
CCDS14 RGRMLSVQCATPSPPTSPASPAPPANPLSSESPRGADSSYTMRV
1010 1020 1030 1040
>>CCDS55809.1 PLEKHA5 gene_id:54477|Hs108|chr12 (76 aa)
initn: 523 init1: 523 opt: 523 Z-score: 402.2 bits: 82.4 E(32554): 4.4e-16
Smith-Waterman score: 523; 100.0% identity (100.0% similar) in 76 aa overlap (1-76:1-76)
10 20 30 40 50 60
pF1KSD MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MAADLNLEWISLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPIS
::::::::::::::::
CCDS55 GWEEAYTFEGARYYIN
70
>>CCDS54291.1 PLEKHA4 gene_id:57664|Hs108|chr19 (583 aa)
initn: 618 init1: 469 opt: 489 Z-score: 363.7 bits: 78.3 E(32554): 6.2e-14
Smith-Waterman score: 489; 46.9% identity (76.2% similar) in 147 aa overlap (117-263:5-148)
90 100 110 120 130 140
pF1KSD PVTGQPSQDNCIFVVNEQTVATMTSEEKKERPISMINEASNYNVTSDYAVHPMSPVGRTS
:: : .. ::. .. : .. .:: . .
CCDS54 MEGSRPRSSLSLASSASTIS--SLSSLSP-KKPT
10 20 30
150 160 170 180 190 200
pF1KSD RASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEK
:: .:.: ::::.:...:.:: :: ::::.::::.:..:::.:::::: :::::.: .
CCDS54 RAVNKIHAFGKRGNALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSR
40 50 60 70 80 90
210 220 230 240 250 260
pF1KSD EEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDA
::..:::.::::..: .:...: : ::.:::: . .:: .... :..:.
CCDS54 EESVLGSVLLPSYNIRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA
100 110 120 130 140 150
270 280 290 300 310 320
pF1KSD ALVQTEPVKRVDKITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIEEKKALEAEK
CCDS54 SRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT
160 170 180 190 200 210
>>CCDS12737.1 PLEKHA4 gene_id:57664|Hs108|chr19 (779 aa)
initn: 694 init1: 469 opt: 489 Z-score: 361.6 bits: 78.3 E(32554): 8e-14
Smith-Waterman score: 499; 24.4% identity (45.8% similar) in 863 aa overlap (117-976:5-606)
90 100 110 120 130 140
pF1KSD PVTGQPSQDNCIFVVNEQTVATMTSEEKKERPISMINEASNYNVTSDYAVHPMSPVGRTS
:: : .. ::. .. : .. .:: . .
CCDS12 MEGSRPRSSLSLASSASTIS--SLSSLSP-KKPT
10 20 30
150 160 170 180 190 200
pF1KSD RASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEK
:: .:.: ::::.:...:.:: :: ::::.::::.:..:::.:::::: :::::.: .
CCDS12 RAVNKIHAFGKRGNALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSR
40 50 60 70 80 90
210 220 230 240 250 260
pF1KSD EEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDA
::..:::.::::..: .:...: : ::.:::: . .:: .... :..:. :
CCDS12 EESVLGSVLLPSYNIRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA
100 110 120 130 140 150
270 280 290 300 310 320
pF1KSD ALVQTEPVKRVDKITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIEEKKALEAEK
. .: :..
CCDS12 S----------------------------------------------------RA-EGDD
330 340 350 360 370 380
pF1KSD YGFQKDGQDRPLTKINSVKLNSLPSEYESGSACPAQTVHYRPINLSSSENKIVNVSLADL
:: : . :: :.: .: . : .. . . .: : ... .:
CCDS12 YG-QPRSPARPQ-----------PGEGPGGPGGPPEVSRGEEGRISESP-EVTRLS----
160 170 180 190 200
390 400 410 420 430 440
pF1KSD RGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKIQKGRGHEEETRGVISYQTLPRNMPSH
:: .:: :.. . . . :.. ......:. . : :
CCDS12 RGRGRP----------RLLTPSPTTD-LHSGLQMRRARSPDLFT-------------PLS
210 220 230
450 460 470 480 490 500
pF1KSD RAQIMARYPEGYRTLPRNSKTRPESICSVTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEW
: : . .::: :.: . : . . .: :. . : :. : .:
CCDS12 R-------PPSPLSLPR-----PRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPL-DW
240 250 260 270 280
510 520 530 540 550 560
pF1KSD QQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHSIPTSPSHGSIAAYQGYSPQRTYRSEV
:...::: : :: : .: . : .: :. .
CCDS12 G-----------PQRQTLSRP--------------PT-PRRGPPSEAGGGKPPRSPQHWS
290 300 310
570 580 590 600 610 620
pF1KSD SSPIQRGDVTIDRRHRAHH--PKHVYVPDRRSVPAGLTLQSVSPQSLQGKTPEELTLLLI
. : : .:: : .. .: : : : . : : : : :.
CCDS12 QEP----------RTQAHSGSPTYLQLPPR---PPGTRASMV----LLPGPPLESTF---
320 330 340 350
630 640 650 660 670 680
pF1KSD KLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQLSQDEGRGTLY
::
CCDS12 -----------------------------------------------HQ-----------
360
690 700 710 720 730 740
pF1KSD KYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAA
.. :. :..:: ::.... :.:...: ..:: :: :: . :.. . . . .:
CCDS12 -----SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGA
370 380 390 400 410
750 760 770 780 790 800
pF1KSD IQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEV
. .. ::. :.:. : . : : ::.: :. :: .. . :. . : : :::
CCDS12 PGRAWGRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETL-EYLLHLGSP
420 430 440 450 460 470
810 820 830 840 850 860
pF1KSD QTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEGPDYRL
: .:.. :..:: ..:.. ::. ::.
CCDS12 Q------DRVSAQQQLWMVEDTLAGLG---------------------------GPQKPP
480 490 500
870 880 890 900 910 920
pF1KSD YKSEPELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKS-PTPESSTIAS
..::. . . : ..:..: : : .: : .. . : : :. .:. . .
CCDS12 PHTEPDSPSPVLQGEESSERESLPES-LELSSPRSPETDWGRPPGGDKDLASPHLGLGSP
510 520 530 540 550 560
930 940 950 960 970 980
pF1KSD YVTLRKTKKMMDLRTERPRSAVEQLCLAESTRPRMTVEEQMERIRRHQQACLREKKKGLN
:. .. . : . :. ... : .::::...::.::.::.:. : :
CCDS12 RVSRASSPEGRHLPS--PQLGTK----APVARPRMSAQEQLERMRRNQE-CGRPFPRPTS
570 580 590 600 610
990 1000 1010 1020 1030 1040
pF1KSD VIGASDQSPLQSPSNLRDNPFRTTQTRRRDDKELDTAIRENDVKPDHETPATEIVQLKET
CCDS12 PRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERV
620 630 640 650 660 670
1174 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:54:51 2016 done: Thu Nov 3 06:54:52 2016
Total Scan time: 4.560 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]