FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1734, 1292 aa 1>>>pF1KSDA1734 1292 - 1292 aa - 1292 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7985+/-0.00101; mu= 9.8011+/- 0.062 mean_var=248.3605+/-49.786, 0's: 0 Z-trim(113.4): 31 B-trim: 565 in 1/55 Lambda= 0.081383 statistics sampled from 13984 (14006) to 13984 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.43), width: 16 Scan time: 3.140 The best scores are: opt bits E(32554) CCDS32742.1 UBE2O gene_id:63893|Hs108|chr17 (1292) 8714 1037.3 0 CCDS33175.2 BIRC6 gene_id:57448|Hs108|chr2 (4857) 504 73.9 1.2e-11 >>CCDS32742.1 UBE2O gene_id:63893|Hs108|chr17 (1292 aa) initn: 8714 init1: 8714 opt: 8714 Z-score: 5539.7 bits: 1037.3 E(32554): 0 Smith-Waterman score: 8714; 99.8% identity (99.9% similar) in 1292 aa overlap (1-1292:1-1292) 10 20 30 40 50 60 pF1KSD MADPAAPTPAAPAPAQAPAPAPEAVPAPAAAPVPAPAPASDSASGPSSDFGPEAGSQRLL ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: CCDS32 MADPAAPTPAAPAPAQAPAPAPEAVPAPAAAPVPAPAPASDSASGPSSDSGPEAGSQRLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGEEEGRGSSGCSEAGGAGHEEGRASPLRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGEEEGRGSSGCSEAGGAGHEEGRASPLRRG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YVRVQWYPEGVKQHVKETKLKLEDRSVVPRDVVRHMRSTDSQCGTVIDVNIDCAVKLIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YVRVQWYPEGVKQHVKETKLKLEDRSVVPRDVVRHMRSTDSQCGTVIDVNIDCAVKLIGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCIIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NCIIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLSGVKPVLSTKSKFRVVVEEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLSGVKPVLSTKSKFRVVVEEVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VVELKVTWITKSFCPGGTDSVSPPPSVITQENLGRVKRLGCFDHAQRQLGERCLYVFPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VVELKVTWITKSFCPGGTDSVSPPPSVITQENLGRVKRLGCFDHAQRQLGERCLYVFPAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VEPAKIAWECPEKNCAQGEGSMAKKVKRLLKKQVVRIMSCSPDTQCSRDHSMEDPDKKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VEPAKIAWECPEKNCAQGEGSMAKKVKRLLKKQVVRIMSCSPDTQCSRDHSMEDPDKKGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SKTKSEAESASPEETPDGSASPVEMQDEGAEEPHEAGEQLPPFLLKEGRDDRLHSAEQDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SKTKSEAESASPEETPDGSASPVEMQDEGAEEPHEAGEQLPPFLLKEGRDDRLHSAEQDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DDEAADDTDDTSSVTSSASSTTSSQSGSGTSRKKSIPLSIKNLKRKHKRKKNKITRDFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DDEAADDTDDTSSVTSSASSTTSSQSGSGTSRKKSIPLSIKNLKRKHKRKKNKITRDFKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GDRVAVEVVTTMTSADVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GDRVAVEVVTTMTSADVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PAVYGVVQSGDHIGRTCMVKWFKLRPSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PAVYGVVQSGDHIGRTCMVKWFKLRPSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD RIGNTEDGAPHKEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RIGNTEDGAPHKEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SVEGSTSGASSDEWEDDSDSWETDNGLVEDEHPKIEEPPIPPLEQPVAPEDKGVVISEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SVEGSTSGASSDEWEDDSDSWETDNGLVEDEHPKIEEPPIPPLEQPVAPEDKGVVISEEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ATAAVQGAVAMAAPMAGLMEKAGKDGPPKSFRELKEAIKILESLKNMTVEQLLTGSPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ATAAVQGAVAMAAPMAGLMEKAGKDGPPKSFRELKEAIKILESLKNMTVEQLLTGSPTSP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TVEPEKPTREKKFLDDIKKLQENLKKTLDNVAIVEEEKMEAVPDVERKEDKPEGQSPVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TVEPEKPTREKKFLDDIKKLQENLKKTLDNVAIVEEEKMEAVPDVERKEDKPEGQSPVKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EWPSETPVLCQQCGGKPGVTFTSAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EWPSETPVLCQQCGGKPGVTFTSAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EMALLATSLPEGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EMALLATSLPEGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD YLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYN 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGGWRLVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGGWRLVN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RIESWLETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPGEASQGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RIESWLETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPGEASQGSD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SEGGAQSLASASRDHTDQTSETAPDASVPPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFP ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SEGGAQGLASASRDHTDQTSETAPDASVPPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 pF1KSD LSKGFIKSIRGVLTQFRAALLEAGMPECTEDK :::::::::::::::::::::::::::::::: CCDS32 LSKGFIKSIRGVLTQFRAALLEAGMPECTEDK 1270 1280 1290 >>CCDS33175.2 BIRC6 gene_id:57448|Hs108|chr2 (4857 aa) initn: 426 init1: 165 opt: 504 Z-score: 322.8 bits: 73.9 E(32554): 1.2e-11 Smith-Waterman score: 506; 31.8% identity (60.9% similar) in 330 aa overlap (830-1146:4456-4774) 800 810 820 830 840 850 pF1KSD EKAGKDGPPKSFRELKEAIKILESLKNMTVEQLLTG-SPTSPTVEPEKPTREKKFLDDIK :.. :: .: . ::: : .. ::. CCDS33 QSECQTSVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTL---LVPDIQ 4430 4440 4450 4460 4470 4480 860 870 880 890 900 910 pF1KSD KLQENLKKTLDNVAIVEEEKMEAVPDVERKED-KPEGQSPVKAEWPSETPVLCQQCGGKP : : . . .. ...:: . . .: ::. : .:. . . :. . CCDS33 KTAEIVYAATTSLRQANQEK--KLGEYSKKAAMKPKPLSVLKSLEEKYVAVMKKLQFD-- 4490 4500 4510 4520 4530 920 930 940 950 960 970 pF1KSD GVTFTSAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVR--KEMALLATSLP----E :: .. . . : : . : ..... . .:.. . : .: . :.:::: CCDS33 --TFEMVSEDEDGKLGFKVNYHYMSQVK-NANDANSAARARRLAQEAVTLSTSLPLSSSS 4540 4550 4560 4570 4580 4590 980 990 1000 1010 1020 pF1KSD GIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFCYLSQCSG---R ...:. :.:.:....:: ::. ::: .: . ::. .:. ::. :: . : .: : CCDS33 SVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPP-LVNLETTGGHSVR 4600 4610 4620 4630 4640 4650 1030 1040 1050 1060 1070 1080 pF1KSD LNPNLYDNGKVCVSLLGTWIGKGTERWTSK-SSLLQVLISIQGLILVNEPYYNEAGFDSD .:::::..::::.:.:.:: :. :.:. . ::.::::.:.:.:::: :::.:: :.. . CCDS33 FNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERS 4660 4670 4680 4690 4700 4710 1090 1100 1110 1120 1130 1140 pF1KSD RGLQEGYENSRCYN-EMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGGWRLVNRIESWL :: : ..:: :. .. : .: . .: : :.. :..:: ... . : :. CCDS33 RGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWI 4720 4730 4740 4750 4760 4770 1150 1160 1170 1180 1190 1200 pF1KSD ETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPGEASQGSDSEGGAQ CCDS33 ADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPDTDDAPEVCRATTGA 4780 4790 4800 4810 4820 4830 1292 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:08:51 2016 done: Thu Nov 3 19:08:52 2016 Total Scan time: 3.140 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]