Result of FASTA (omim) for
pF1KSDA1735
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1735, 472 aa
1>>>pF1KSDA1735 472 - 472 aa - 472 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8187+/-0.000434; mu= -2.6780+/- 0.027
mean_var=300.6491+/-61.036, 0's: 0 Z-trim(118.9): 20 B-trim: 0 in 0/59
Lambda= 0.073968
statistics sampled from 32346 (32366) to 32346 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.379), width: 16
Scan time: 11.170
The best scores are: opt bits E(85289)
NP_219493 (OMIM: 610493) dixin isoform b [Homo sap ( 472) 3112 345.9 1.4e-94
XP_016873955 (OMIM: 610493) PREDICTED: dixin isofo ( 682) 3054 339.9 1.3e-92
XP_016873956 (OMIM: 610493) PREDICTED: dixin isofo ( 682) 3054 339.9 1.3e-92
NP_001033043 (OMIM: 610493) dixin isoform a [Homo ( 683) 3054 339.9 1.3e-92
XP_016873957 (OMIM: 610493) PREDICTED: dixin isofo ( 389) 2561 287.0 6.1e-77
XP_016873958 (OMIM: 610493) PREDICTED: dixin isofo ( 387) 2489 279.4 1.2e-74
>>NP_219493 (OMIM: 610493) dixin isoform b [Homo sapiens (472 aa)
initn: 3112 init1: 3112 opt: 3112 Z-score: 1819.0 bits: 345.9 E(85289): 1.4e-94
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 472 aa overlap (1-472:1-472)
10 20 30 40 50 60
pF1KSD MGGTQVKCLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 MGGTQVKCLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 PGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 PEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 LLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 SYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 DLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 QVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFK
370 380 390 400 410 420
430 440 450 460 470
pF1KSD AAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_219 AAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
430 440 450 460 470
>>XP_016873955 (OMIM: 610493) PREDICTED: dixin isoform X (682 aa)
initn: 3053 init1: 3053 opt: 3054 Z-score: 1783.5 bits: 339.9 E(85289): 1.3e-92
Smith-Waterman score: 3054; 98.7% identity (99.4% similar) in 471 aa overlap (4-472:212-682)
10 20 30
pF1KSD MGGTQVKC--LTSPSPIHSAKSESIITQSEEKA
.. .: :::::::::::::::::::::::
XP_016 RNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKA
190 200 210 220 230 240
40 50 60 70 80 90
pF1KSD DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
250 260 270 280 290 300
100 110 120 130 140 150
pF1KSD SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
310 320 330 340 350 360
160 170 180 190 200 210
pF1KSD EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
370 380 390 400 410 420
220 230 240 250 260 270
pF1KSD YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
430 440 450 460 470 480
280 290 300 310 320 330
pF1KSD YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
490 500 510 520 530 540
340 350 360 370 380 390
pF1KSD GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
550 560 570 580 590 600
400 410 420 430 440 450
pF1KSD VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
610 620 630 640 650 660
460 470
pF1KSD DAIPGWEGKIVAWVEEDHGEN
:::::::::::::::::::::
XP_016 DAIPGWEGKIVAWVEEDHGEN
670 680
>>XP_016873956 (OMIM: 610493) PREDICTED: dixin isoform X (682 aa)
initn: 3053 init1: 3053 opt: 3054 Z-score: 1783.5 bits: 339.9 E(85289): 1.3e-92
Smith-Waterman score: 3054; 98.7% identity (99.4% similar) in 471 aa overlap (4-472:212-682)
10 20 30
pF1KSD MGGTQVKC--LTSPSPIHSAKSESIITQSEEKA
.. .: :::::::::::::::::::::::
XP_016 RNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKA
190 200 210 220 230 240
40 50 60 70 80 90
pF1KSD DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
250 260 270 280 290 300
100 110 120 130 140 150
pF1KSD SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
310 320 330 340 350 360
160 170 180 190 200 210
pF1KSD EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
370 380 390 400 410 420
220 230 240 250 260 270
pF1KSD YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
430 440 450 460 470 480
280 290 300 310 320 330
pF1KSD YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
490 500 510 520 530 540
340 350 360 370 380 390
pF1KSD GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
550 560 570 580 590 600
400 410 420 430 440 450
pF1KSD VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
610 620 630 640 650 660
460 470
pF1KSD DAIPGWEGKIVAWVEEDHGEN
:::::::::::::::::::::
XP_016 DAIPGWEGKIVAWVEEDHGEN
670 680
>>NP_001033043 (OMIM: 610493) dixin isoform a [Homo sapi (683 aa)
initn: 3053 init1: 3053 opt: 3054 Z-score: 1783.5 bits: 339.9 E(85289): 1.3e-92
Smith-Waterman score: 3054; 98.7% identity (99.4% similar) in 471 aa overlap (4-472:213-683)
10 20 30
pF1KSD MGGTQVKC--LTSPSPIHSAKSESIITQSEEKA
.. .: :::::::::::::::::::::::
NP_001 RNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKA
190 200 210 220 230 240
40 50 60 70 80 90
pF1KSD DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMI
250 260 270 280 290 300
100 110 120 130 140 150
pF1KSD SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQ
310 320 330 340 350 360
160 170 180 190 200 210
pF1KSD EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGE
370 380 390 400 410 420
220 230 240 250 260 270
pF1KSD YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATN
430 440 450 460 470 480
280 290 300 310 320 330
pF1KSD YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQ
490 500 510 520 530 540
340 350 360 370 380 390
pF1KSD GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTK
550 560 570 580 590 600
400 410 420 430 440 450
pF1KSD VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDD
610 620 630 640 650 660
460 470
pF1KSD DAIPGWEGKIVAWVEEDHGEN
:::::::::::::::::::::
NP_001 DAIPGWEGKIVAWVEEDHGEN
670 680
>>XP_016873957 (OMIM: 610493) PREDICTED: dixin isoform X (389 aa)
initn: 2561 init1: 2561 opt: 2561 Z-score: 1502.3 bits: 287.0 E(85289): 6.1e-77
Smith-Waterman score: 2561; 100.0% identity (100.0% similar) in 389 aa overlap (84-472:1-389)
60 70 80 90 100 110
pF1KSD RDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLA
::::::::::::::::::::::::::::::
XP_016 MEEAKKMISGLQALLLNGSLPEDEQERPLA
10 20 30
120 130 140 150 160 170
pF1KSD LCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTS
40 50 60 70 80 90
180 190 200 210 220 230
pF1KSD VLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KSD LRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATS
160 170 180 190 200 210
300 310 320 330 340 350
pF1KSD VSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KSD RVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEE
280 290 300 310 320 330
420 430 440 450 460 470
pF1KSD VTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
340 350 360 370 380
>>XP_016873958 (OMIM: 610493) PREDICTED: dixin isoform X (387 aa)
initn: 2489 init1: 2489 opt: 2489 Z-score: 1460.8 bits: 279.4 E(85289): 1.2e-74
Smith-Waterman score: 2489; 99.7% identity (100.0% similar) in 378 aa overlap (95-472:10-387)
70 80 90 100 110 120
pF1KSD LETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQ
.:::::::::::::::::::::::::::::
XP_016 MDLTKGTSPRALLLNGSLPEDEQERPLALCEPGVNPEEQ
10 20 30
130 140 150 160 170 180
pF1KSD LIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD NMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQ
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD VDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD VRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRTQVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRTQVGS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KSD EYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAID
280 290 300 310 320 330
430 440 450 460 470
pF1KSD REGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
340 350 360 370 380
472 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:09:57 2016 done: Thu Nov 3 07:09:59 2016
Total Scan time: 11.170 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]