FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1750, 417 aa 1>>>pF1KSDA1750 417 - 417 aa - 417 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3125+/-0.000319; mu= 14.3756+/- 0.020 mean_var=131.1748+/-26.827, 0's: 0 Z-trim(120.1): 34 B-trim: 839 in 2/56 Lambda= 0.111982 statistics sampled from 34848 (34882) to 34848 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.409), width: 16 Scan time: 10.370 The best scores are: opt bits E(85289) NP_277047 (OMIM: 614721) testis-specific Y-encoded ( 417) 2807 464.5 2.1e-130 NP_003300 (OMIM: 604714,608800) testis-specific Y- ( 437) 784 137.7 5.4e-32 NP_071400 (OMIM: 300564) testis-specific Y-encoded ( 693) 672 119.8 2.1e-26 XP_006724655 (OMIM: 300564) PREDICTED: testis-spec ( 694) 672 119.8 2.1e-26 NP_003299 (OMIM: 480100) testis-specific Y-encoded ( 308) 538 97.8 3.9e-20 NP_001307893 (OMIM: 480100) testis-specific Y-enco ( 221) 493 90.4 4.7e-18 NP_001184171 (OMIM: 480100) testis-specific Y-enco ( 294) 470 86.8 7.6e-17 NP_001116293 (OMIM: 600960) protein SET isoform 1 ( 290) 418 78.4 2.5e-14 XP_016870503 (OMIM: 600960) PREDICTED: protein SET ( 309) 418 78.5 2.6e-14 XP_016870504 (OMIM: 600960) PREDICTED: protein SET ( 309) 418 78.5 2.6e-14 XP_016870502 (OMIM: 600960) PREDICTED: protein SET ( 309) 418 78.5 2.6e-14 NP_001234930 (OMIM: 600960) protein SET isoform 4 ( 266) 397 75.0 2.5e-13 NP_001234929 (OMIM: 600960) protein SET isoform 3 ( 268) 394 74.5 3.5e-13 NP_003002 (OMIM: 600960) protein SET isoform 2 [Ho ( 277) 394 74.5 3.6e-13 XP_016870505 (OMIM: 600960) PREDICTED: protein SET ( 296) 394 74.6 3.8e-13 XP_016885216 (OMIM: 300564) PREDICTED: testis-spec ( 737) 393 74.8 8e-13 XP_016885215 (OMIM: 300564) PREDICTED: testis-spec ( 738) 393 74.8 8e-13 XP_016885553 (OMIM: 480100) PREDICTED: testis-spec ( 288) 359 68.9 1.9e-11 >>NP_277047 (OMIM: 614721) testis-specific Y-encoded-lik (417 aa) initn: 2807 init1: 2807 opt: 2807 Z-score: 2462.0 bits: 464.5 E(85289): 2.1e-130 Smith-Waterman score: 2807; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KSD MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAASLSERLAADT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 GLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAASLSERLAADT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 VFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AGEEKKEERDAGSGPPATEGSMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 AGEEKKEERDAGSGPPATEGSMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNHLIQNIPGFWGQAFQNHPQLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 RNHLIQNIPGFWGQAFQNHPQLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 NPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSI 310 320 330 340 350 360 370 380 390 400 410 pF1KSD ESDKIVEIINEELWPNPLQFYLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_277 ESDKIVEIINEELWPNPLQFYLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN 370 380 390 400 410 >>NP_003300 (OMIM: 604714,608800) testis-specific Y-enco (437 aa) initn: 835 init1: 742 opt: 784 Z-score: 695.4 bits: 137.7 E(85289): 5.4e-32 Smith-Waterman score: 852; 39.8% identity (62.8% similar) in 425 aa overlap (30-416:22-436) 10 20 30 40 50 60 pF1KSD MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWG :..: : : :: : ....:.::.: : : NP_003 MSGLDGVKRTTPLQTHSIIISDQVPSDQDAHQYLRLRDQSEATQVMAEPGEG 10 20 30 40 50 70 80 90 100 110 pF1KSD GLEAAASAQLLRLGEEAACRLPLDC---GLALRARAAGDHGQAAARPGPGKAASLSERLA : :..: .::.. .: : : . . :..: .:..: . : .. .: :: NP_003 GSETVALPPP-PPSEEGG--VPQDAAGRGGTPQIRVVGGRGHVAIKAGQEEGQPPAEGLA 60 70 80 90 100 120 130 140 150 pF1KSD ADTVFVGT-----AGTVGRPKNAPRVGNRRGP----AGKKAPET------CSTAG----- : .: ... :. : : : .:. :: .: :.:.. NP_003 AASVVMAADRSLKKGVQGGEKALEICGAQRSASELTAGAEAEAEEVKTGKCATVSAAVAE 110 120 130 140 150 160 160 170 180 190 200 pF1KSD -RGPQVIAGGRQKKGAA------------GENTSVSAGEEKKEERDAGSGP-PATEG-SM .. .:. : .: . ::. :. .. .:: :: : :. : NP_003 RESAEVVKEGLAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRM 170 180 190 200 210 220 210 220 230 240 250 260 pF1KSD DTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQL : :: .::.:...:::::::. .: .:::..: ..:::::..:::::::: ::.::::: NP_003 DPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQL 230 240 250 260 270 280 270 280 290 300 310 320 pF1KSD ASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVV .... .:. :.: :...:::.:: : : :.::.: :::::.::...::: ::.:: NP_003 SAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVV 290 300 310 320 330 340 330 340 350 360 370 380 pF1KSD SRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQFYL : :::: : ::. ::. . : . ::: :::.:: :::::.:::.:.:::::::.:: NP_003 SLSTPIIWRRGHEPQSFIRRNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYL 350 360 370 380 390 400 390 400 410 pF1KSD LSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN : ::.: ..:. : ..:.: .: :: NP_003 LREGVR-------RARRRPLREPVEIPRPFGFQSG 410 420 430 >>NP_071400 (OMIM: 300564) testis-specific Y-encoded-lik (693 aa) initn: 735 init1: 659 opt: 672 Z-score: 595.1 bits: 119.8 E(85289): 2.1e-26 Smith-Waterman score: 733; 34.5% identity (62.9% similar) in 420 aa overlap (13-403:10-418) 10 20 30 40 50 pF1KSD MSGRSRGRKSSRAKNRGKGRAKARVR-PAPDDAPRD------PDPSQYQSLGEDTQAAQV ::.: . ... : : : : : :.: : :.:.:::: NP_071 MDRPDEGPPAKTRRLSSSESPQRDPPPPPPPPPLLRLPLPPPQQRPRLQEETEAAQV 10 20 30 40 50 60 70 80 90 100 110 pF1KSD QA---GAGWGGLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAA : :.: : : . ::.. : . : :. : ... . : :.: NP_071 LADMRGVGLG--PALPPPPPYVILEEGGIRAYFTLG----AECPG--WDSTIESGYGEAP 60 70 80 90 100 120 130 140 150 160 170 pF1KSD SLSERLAADTVFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKK .: : : . ...:.. . .: . . .:. : ::::..: .:: .. ..:. NP_071 PPTESLEALPTPEASGGSL---EIDFQVVQSSSFGGEGALETCSAVGWAPQRLVDPKSKE 110 120 130 140 150 160 180 190 200 210 pF1KSD GAA--------GENTSVSAGEEKKEERDAGS----------GPPATEGSMDTLENVQLKL : : :. ........: . . :. ...::..:: : NP_071 EAIIIVEDEDEDERESMRSSRRRRRRRRRKQRKVKRESRERNAERMESILQALEDIQLDL 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD ENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLASFLNSQEKE : .: .: .:.:::.::: :.: ::::. .::.::::: .:: :::... ..: .... NP_071 EAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINRRDED 230 240 250 260 270 280 280 290 300 310 320 330 pF1KSD VLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLP .. ::..:.:..: .:::.:.::. :::: : :..::. . ::..::.::::.: NP_071 IFRYLTNLQVQDLRHISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHR 290 300 310 320 330 340 340 350 360 370 380 390 pF1KSD GHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQFYLLSEGARVEKG :.. :. .:: . ..:::.:::::: :.:.:.:::...:: :::..:: .:.:... NP_071 GQEPQARRHGNQDASHSFFSWFSNHSLPEADRIAEIIKNDLWVNPLRYYLRERGSRIKRK 350 360 370 380 390 400 400 410 pF1KSD K-EKEGRQGPGKQPMETTQPGVSQSN : : . :. :. NP_071 KQEMKKRKTRGRCEVVIMEDAPDYYAVEDIFSEISDIDETIHDIKISDFMETTDYFETTD 410 420 430 440 450 460 >>XP_006724655 (OMIM: 300564) PREDICTED: testis-specific (694 aa) initn: 735 init1: 659 opt: 672 Z-score: 595.1 bits: 119.8 E(85289): 2.1e-26 Smith-Waterman score: 733; 34.5% identity (62.9% similar) in 420 aa overlap (13-403:10-418) 10 20 30 40 50 pF1KSD MSGRSRGRKSSRAKNRGKGRAKARVR-PAPDDAPRD------PDPSQYQSLGEDTQAAQV ::.: . ... : : : : : :.: : :.:.:::: XP_006 MDRPDEGPPAKTRRLSSSESPQRDPPPPPPPPPLLRLPLPPPQQRPRLQEETEAAQV 10 20 30 40 50 60 70 80 90 100 110 pF1KSD QA---GAGWGGLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAA : :.: : : . ::.. : . : :. : ... . : :.: XP_006 LADMRGVGLG--PALPPPPPYVILEEGGIRAYFTLG----AECPG--WDSTIESGYGEAP 60 70 80 90 100 120 130 140 150 160 170 pF1KSD SLSERLAADTVFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKK .: : : . ...:.. . .: . . .:. : ::::..: .:: .. ..:. XP_006 PPTESLEALPTPEASGGSL---EIDFQVVQSSSFGGEGALETCSAVGWAPQRLVDPKSKE 110 120 130 140 150 160 180 190 200 210 pF1KSD GAA--------GENTSVSAGEEKKEERDAGS----------GPPATEGSMDTLENVQLKL : : :. ........: . . :. ...::..:: : XP_006 EAIIIVEDEDEDERESMRSSRRRRRRRRRKQRKVKRESRERNAERMESILQALEDIQLDL 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD ENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLASFLNSQEKE : .: .: .:.:::.::: :.: ::::. .::.::::: .:: :::... ..: .... XP_006 EAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINRRDED 230 240 250 260 270 280 280 290 300 310 320 330 pF1KSD VLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLP .. ::..:.:..: .:::.:.::. :::: : :..::. . ::..::.::::.: XP_006 IFRYLTNLQVQDLRHISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHR 290 300 310 320 330 340 340 350 360 370 380 390 pF1KSD GHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQFYLLSEGARVEKG :.. :. .:: . ..:::.:::::: :.:.:.:::...:: :::..:: .:.:... XP_006 GQEPQARRHGNQDASHSFFSWFSNHSLPEADRIAEIIKNDLWVNPLRYYLRERGSRIKRK 350 360 370 380 390 400 400 410 pF1KSD K-EKEGRQGPGKQPMETTQPGVSQSN : : . :. :. XP_006 KQEMKKRKTRGRCEVVIMEDAPDYYAVEDIFSEISDIDETIHDIKISDFMETTDYFETTD 410 420 430 440 450 460 >>NP_003299 (OMIM: 480100) testis-specific Y-encoded pro (308 aa) initn: 556 init1: 523 opt: 538 Z-score: 482.6 bits: 97.8 E(85289): 3.9e-20 Smith-Waterman score: 538; 38.8% identity (69.2% similar) in 227 aa overlap (173-397:78-302) 150 160 170 180 190 200 pF1KSD GPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDA--GSGPPATEG : :. : :: .. ..: : :: . :. NP_003 GAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPES 50 60 70 80 90 100 210 220 230 240 250 260 pF1KSD SMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHP . . : ::..:: .:::: .:. : .:. . : ::.::. .::..::::.... ::: NP_003 APEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHP 110 120 130 140 150 160 270 280 290 300 310 320 pF1KSD QLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQ :............:::. :::: : :: ..: ::::::::. ::: . . NP_003 QMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEY 170 180 190 200 210 220 330 340 350 360 370 380 pF1KSD VVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQF .:.::::.: : ..... . . ... .::.:::.:. :.::.::. ..:: ::::. NP_003 RASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQY 230 240 250 260 270 280 390 400 410 pF1KSD YLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN : . :.: : : NP_003 YKRMKPP--EEGTETSGDSQLLS 290 300 >>NP_001307893 (OMIM: 480100) testis-specific Y-encoded (221 aa) initn: 489 init1: 489 opt: 493 Z-score: 445.1 bits: 90.4 E(85289): 4.7e-18 Smith-Waterman score: 493; 40.7% identity (74.1% similar) in 189 aa overlap (210-397:30-215) 180 190 200 210 220 230 pF1KSD SAGEEKKEERDAGSGPPATEGSMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLE ..:: .:::: .:. : .:. . : ::. NP_001 MRPEGSLTYRVPERLRQGFCGVGRAAQALVELEPVNAQARKAFSRQREKMERRRKPHLD 10 20 30 40 50 240 250 260 270 280 290 pF1KSD RRNHLIQNIPGFWGQAFQNHPQLASFLNSQEKEVLSYLNSLEV-EELGLARLGYKIKFYF ::. .::..::::.... ::::............:::. :::: :: ..: :: ..: NP_001 RRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLC-KIMLFF 60 70 80 90 100 110 300 310 320 330 340 350 pF1KSD DRNPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHS ::::::::. ::: . . .:.::::.: : ..... . . ... .::.:::.:. NP_001 RSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHN 120 130 140 150 160 170 360 370 380 390 400 410 pF1KSD SIESDKIVEIINEELWPNPLQFYLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN :.::.::. ..:: ::::.: .. :.: : : NP_001 FAGSNKIAEILCKDLWRNPLQYY--KRMKPPEEGTETSGDSQLLS 180 190 200 210 220 >>NP_001184171 (OMIM: 480100) testis-specific Y-encoded (294 aa) initn: 490 init1: 457 opt: 470 Z-score: 423.5 bits: 86.8 E(85289): 7.6e-17 Smith-Waterman score: 470; 38.6% identity (70.6% similar) in 197 aa overlap (173-367:78-274) 150 160 170 180 190 200 pF1KSD GPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDA--GSGPPATEG : :. : :: .. ..: : :: . :. NP_001 GAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPES 50 60 70 80 90 100 210 220 230 240 250 260 pF1KSD SMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHP . . : ::..:: .:::: .:. : .:. . : ::.::. .::..::::.... ::: NP_001 APEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHP 110 120 130 140 150 160 270 280 290 300 310 320 pF1KSD QLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQ :............:::. :::: : :: ..: ::::::::. ::: . . NP_001 QMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEY 170 180 190 200 210 220 330 340 350 360 370 380 pF1KSD VVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQF .:.::::.: : ..... . . ... .::.:::.:. :.::.: NP_001 RASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAESPDRSYVRTCGAI 230 240 250 260 270 280 390 400 410 pF1KSD YLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN NP_001 PCNTTRG 290 >>NP_001116293 (OMIM: 600960) protein SET isoform 1 [Hom (290 aa) initn: 561 init1: 386 opt: 418 Z-score: 378.1 bits: 78.4 E(85289): 2.5e-14 Smith-Waterman score: 555; 37.9% identity (68.8% similar) in 240 aa overlap (175-400:25-257) 150 160 170 180 190 200 pF1KSD AGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDAGSGPPATEGSMDT :.::.::: :: :.. . ... NP_001 MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEKEQ-------QEAIEH 10 20 30 40 210 220 230 240 250 260 pF1KSD LENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLAS ...:: ... .: ::.. :.. .:...:: ...:..:: .::.:: .: ::::... NP_001 IDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSA 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD FLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVVSR .:. ...:.: ::. .:: :. . ::.: ::::.::::.:::: ::. . ::. :. NP_001 LLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSK 110 120 130 140 150 160 330 340 350 360 370 pF1KSD STPIQWLPGHDL---QSLSQGNPENNR------SFFGWFSNHSSIESDKIVEIINEELWP :: :.: :.:: .: .:.. .: ::: ::..::. .:.. :.:....:: NP_001 STEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWP 170 180 190 200 210 220 380 390 400 410 pF1KSD NPLQFYLLS-----EGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN ::::.::. :: : . : ..: NP_001 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEG 230 240 250 260 270 280 >>XP_016870503 (OMIM: 600960) PREDICTED: protein SET iso (309 aa) initn: 561 init1: 386 opt: 418 Z-score: 377.8 bits: 78.5 E(85289): 2.6e-14 Smith-Waterman score: 555; 37.9% identity (68.8% similar) in 240 aa overlap (175-400:25-257) 150 160 170 180 190 200 pF1KSD AGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDAGSGPPATEGSMDT :.::.::: :: :.. . ... XP_016 MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEKEQ-------QEAIEH 10 20 30 40 210 220 230 240 250 260 pF1KSD LENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLAS ...:: ... .: ::.. :.. .:...:: ...:..:: .::.:: .: ::::... XP_016 IDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSA 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD FLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVVSR .:. ...:.: ::. .:: :. . ::.: ::::.::::.:::: ::. . ::. :. XP_016 LLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSK 110 120 130 140 150 160 330 340 350 360 370 pF1KSD STPIQWLPGHDL---QSLSQGNPENNR------SFFGWFSNHSSIESDKIVEIINEELWP :: :.: :.:: .: .:.. .: ::: ::..::. .:.. :.:....:: XP_016 STEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWP 170 180 190 200 210 220 380 390 400 410 pF1KSD NPLQFYLLS-----EGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN ::::.::. :: : . : ..: XP_016 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEVKEN 230 240 250 260 270 280 >>XP_016870504 (OMIM: 600960) PREDICTED: protein SET iso (309 aa) initn: 561 init1: 386 opt: 418 Z-score: 377.8 bits: 78.5 E(85289): 2.6e-14 Smith-Waterman score: 555; 37.9% identity (68.8% similar) in 240 aa overlap (175-400:25-257) 150 160 170 180 190 200 pF1KSD AGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDAGSGPPATEGSMDT :.::.::: :: :.. . ... XP_016 MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEKEQ-------QEAIEH 10 20 30 40 210 220 230 240 250 260 pF1KSD LENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHPQLAS ...:: ... .: ::.. :.. .:...:: ...:..:: .::.:: .: ::::... XP_016 IDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSA 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD FLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQVVSR .:. ...:.: ::. .:: :. . ::.: ::::.::::.:::: ::. . ::. :. XP_016 LLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSK 110 120 130 140 150 160 330 340 350 360 370 pF1KSD STPIQWLPGHDL---QSLSQGNPENNR------SFFGWFSNHSSIESDKIVEIINEELWP :: :.: :.:: .: .:.. .: ::: ::..::. .:.. :.:....:: XP_016 STEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWP 170 180 190 200 210 220 380 390 400 410 pF1KSD NPLQFYLLS-----EGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN ::::.::. :: : . : ..: XP_016 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEVKEN 230 240 250 260 270 280 417 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:13:51 2016 done: Thu Nov 3 07:13:52 2016 Total Scan time: 10.370 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]