FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1753, 810 aa 1>>>pF1KSDA1753 810 - 810 aa - 810 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4410+/-0.000869; mu= 2.4461+/- 0.052 mean_var=213.4617+/-42.928, 0's: 0 Z-trim(114.5): 14 B-trim: 0 in 0/53 Lambda= 0.087784 statistics sampled from 15086 (15095) to 15086 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.464), width: 16 Scan time: 5.000 The best scores are: opt bits E(32554) CCDS45778.2 UNK gene_id:85451|Hs108|chr17 ( 810) 5631 726.1 5.7e-209 CCDS32359.1 UNKL gene_id:64718|Hs108|chr16 ( 277) 1326 180.6 3.1e-45 CCDS61787.1 UNKL gene_id:64718|Hs108|chr16 ( 229) 618 90.9 2.6e-18 >>CCDS45778.2 UNK gene_id:85451|Hs108|chr17 (810 aa) initn: 5631 init1: 5631 opt: 5631 Z-score: 3865.2 bits: 726.1 E(32554): 5.7e-209 Smith-Waterman score: 5631; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFER 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSEN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD TFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANST 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD IKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD HAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKRAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKRAVL 730 740 750 760 770 780 790 800 810 pF1KSD PCQHAALCELCAEGSECPICQPGRAHTLQS :::::::::::::::::::::::::::::: CCDS45 PCQHAALCELCAEGSECPICQPGRAHTLQS 790 800 810 >>CCDS32359.1 UNKL gene_id:64718|Hs108|chr16 (277 aa) initn: 1328 init1: 970 opt: 1326 Z-score: 925.6 bits: 180.6 E(32554): 3.1e-45 Smith-Waterman score: 1326; 74.0% identity (87.6% similar) in 242 aa overlap (14-252:3-244) 10 20 30 40 50 pF1KSD MSKGPGPGGSAASSAPPAATAQVLQAQP--EKPQHYTYLKEFRTEQCPLFVQHKCTQHRP :. ::.: . . : ::: :: ::::::::::::: ::::.:::: CCDS32 MPSVSKAAAAALSGSPPQTEKPTHYRYLKEFRTEQCPLFSQHKCAQHRP 10 20 30 40 60 70 80 90 100 110 pF1KSD YTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTER .:::::::.:::::: .:::::::::::::::.::.::::.::.:::::.:::::::::: CCDS32 FTCFHWHFLNQRRRRPLRRRDGTFNYSPDVYCSKYNEATGVCPDGDECPYLHRTTGDTER 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD RYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTT .::::::::: ::::::..:.:.:::::::::::: ::: :: :.:::::.::::::: CCDS32 KYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPLDLRPPVCDVRELQAQEALQNGQLG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD V-EGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYY :: . : . ::.:::::::::.::::.. .:::.:::: : :::::::::::::.: CCDS32 GGEGVPDLQPGVLASQAMIEKILSEDPRWQDANFVLGSYKTEQCPKPPRLCRQGYACPHY 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD HNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKST :::.::::.::. .: CCDS32 HNSRDRRRNPRRFQYSWQLGRRVLRLSPRANNPRVALPRVHTGPSSTA 230 240 250 260 270 >>CCDS61787.1 UNKL gene_id:64718|Hs108|chr16 (229 aa) initn: 540 init1: 439 opt: 618 Z-score: 442.2 bits: 90.9 E(32554): 2.6e-18 Smith-Waterman score: 618; 48.8% identity (74.9% similar) in 203 aa overlap (613-802:25-226) 590 600 610 620 630 640 pF1KSD LSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGP ::::. .:::. :.::::::. :: . .:: CCDS61 MTCCSQVPPRRRPSLALSPRLDCNGLNGVPGSIWD-FVSGSFSPSPSPILSAGP 10 20 30 40 50 650 660 670 680 690 pF1KSD --------GAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGA ..:::::.:..::::. :.::::::.:.::.::::..::.:: ::: .: . CCDS61 PSSSSASPNGAELARVRRQLDEAKRKIRQWEESWQQVKQVCDAWQREAQEAKERARVADS 60 70 80 90 100 110 700 710 720 730 740 750 pF1KSD ECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHL . .:: .... .:.:::.:::::: : .. .: . .:. .. : :.:::.::: : CCDS61 DRQLALQKKEEVEAQVKQLQEELEGLGVASTLPGLRGCGDIGTIPLPKLHSLQSQLRLDL 120 130 140 150 160 170 760 770 780 790 800 pF1KSD EQVDKAVFHMQSVKCLKCQEQKR-AVL-PCQHAALCELCAEGS-ECPIC--QPGRAHTLQ : :: ..:.... .:. :.:. . ::: :::: ::: :: . ::: : :: CCDS61 EAVDGVIFQLRAKQCVACRERAHGAVLRPCQHHILCEPCAATAPECPYCKGQPLQW 180 190 200 210 220 810 pF1KSD S 810 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:14:30 2016 done: Thu Nov 3 07:14:31 2016 Total Scan time: 5.000 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]