Result of FASTA (omim) for
pF1KSDA1810
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1810, 565 aa
1>>>pF1KSDA1810 565 - 565 aa - 565 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.8046+/-0.000484; mu= -16.5942+/- 0.030
mean_var=738.8039+/-154.647, 0's: 0 Z-trim(125.4): 49 B-trim: 937 in 1/61
Lambda= 0.047186
statistics sampled from 48904 (48981) to 48904 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.574), width: 16
Scan time: 13.380
The best scores are: opt bits E(85289)
NP_115807 (OMIM: 608046) E3 ubiquitin-protein liga ( 616) 3042 222.2 3.8e-57
NP_757385 (OMIM: 608046) E3 ubiquitin-protein liga ( 617) 3030 221.4 6.7e-57
XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquiti ( 617) 3030 221.4 6.7e-57
>>NP_115807 (OMIM: 608046) E3 ubiquitin-protein ligase s (616 aa)
initn: 3853 init1: 3042 opt: 3042 Z-score: 1147.0 bits: 222.2 E(85289): 3.8e-57
Smith-Waterman score: 3646; 91.5% identity (91.5% similar) in 597 aa overlap (20-565:20-616)
10 20 30 40 50 60
pF1KSD MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
:::::::::::::::::::::::::::::::::::::::::
NP_115 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
70 80 90 100 110 120
pF1KSD EDRVDF---------------------------------------------------YAI
:::::: :::
NP_115 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD AGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVN
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA
550 560 570 580 590 600
550 560
pF1KSD ELRRRRLQKLESPVAH
::::::::::::::::
NP_115 ELRRRRLQKLESPVAH
610
>>NP_757385 (OMIM: 608046) E3 ubiquitin-protein ligase s (617 aa)
initn: 2511 init1: 1700 opt: 3030 Z-score: 1142.6 bits: 221.4 E(85289): 6.7e-57
Smith-Waterman score: 3634; 91.3% identity (91.3% similar) in 598 aa overlap (20-565:20-617)
10 20 30 40 50 60
pF1KSD MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
:::::::::::::::::::::::::::::::::::::::::
NP_757 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
70 80 90 100 110 120
pF1KSD EDRVDF---------------------------------------------------YAI
:::::: :::
NP_757 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAA-LSRPSGA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_757 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
550 560 570 580 590 600
550 560
pF1KSD AELRRRRLQKLESPVAH
:::::::::::::::::
NP_757 AELRRRRLQKLESPVAH
610
>>XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquitin-pr (617 aa)
initn: 2511 init1: 1700 opt: 3030 Z-score: 1142.6 bits: 221.4 E(85289): 6.7e-57
Smith-Waterman score: 3634; 91.3% identity (91.3% similar) in 598 aa overlap (20-565:20-617)
10 20 30 40 50 60
pF1KSD MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
:::::::::::::::::::::::::::::::::::::::::
XP_011 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
70 80 90 100 110 120
pF1KSD EDRVDF---------------------------------------------------YAI
:::::: :::
XP_011 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAA-LSRPSGA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
550 560 570 580 590 600
550 560
pF1KSD AELRRRRLQKLESPVAH
:::::::::::::::::
XP_011 AELRRRRLQKLESPVAH
610
565 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:24:55 2016 done: Thu Nov 3 07:24:57 2016
Total Scan time: 13.380 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]