Result of FASTA (omim) for
pF1KSDA1835
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1835, 587 aa
1>>>pF1KSDA1835 587 - 587 aa - 587 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8571+/-0.000533; mu= -5.9570+/- 0.034
mean_var=398.5269+/-77.201, 0's: 0 Z-trim(119.6): 64 B-trim: 0 in 0/57
Lambda= 0.064246
statistics sampled from 33859 (33923) to 33859 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.398), width: 16
Scan time: 12.150
The best scores are: opt bits E(85289)
XP_016884383 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
NP_001265580 (OMIM: 602362) ran GTPase-activating ( 587) 3715 359.0 2.5e-98
NP_002874 (OMIM: 602362) ran GTPase-activating pro ( 587) 3715 359.0 2.5e-98
XP_016884385 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_016884386 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_016884382 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
NP_001304859 (OMIM: 602362) ran GTPase-activating ( 587) 3715 359.0 2.5e-98
XP_011528596 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_016884384 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_006724352 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_011528597 (OMIM: 602362) PREDICTED: ran GTPase- ( 587) 3715 359.0 2.5e-98
XP_005261753 (OMIM: 602362) PREDICTED: ran GTPase- ( 628) 3715 359.1 2.6e-98
XP_005261752 (OMIM: 602362) PREDICTED: ran GTPase- ( 642) 3715 359.1 2.6e-98
XP_016884387 (OMIM: 602362) PREDICTED: ran GTPase- ( 554) 3496 338.7 3e-92
XP_016884388 (OMIM: 602362) PREDICTED: ran GTPase- ( 542) 2422 239.1 2.8e-62
XP_011528595 (OMIM: 602362) PREDICTED: ran GTPase- ( 597) 2422 239.2 3e-62
XP_011528599 (OMIM: 602362) PREDICTED: ran GTPase- ( 439) 2262 224.2 7e-58
>>XP_016884383 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>NP_001265580 (OMIM: 602362) ran GTPase-activating prot (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>NP_002874 (OMIM: 602362) ran GTPase-activating protein (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_016884385 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_016884386 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_016884382 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>NP_001304859 (OMIM: 602362) ran GTPase-activating prot (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_011528596 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_016884384 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
>>XP_006724352 (OMIM: 602362) PREDICTED: ran GTPase-acti (587 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1886.4 bits: 359.0 E(85289): 2.5e-98
Smith-Waterman score: 3715; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KSD MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLM
490 500 510 520 530 540
550 560 570 580
pF1KSD ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
550 560 570 580
587 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:28:41 2016 done: Thu Nov 3 07:28:43 2016
Total Scan time: 12.150 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]