FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1848, 404 aa 1>>>pF1KSDA1848 404 - 404 aa - 404 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6585+/-0.000374; mu= 7.0679+/- 0.023 mean_var=147.2821+/-30.405, 0's: 0 Z-trim(117.8): 125 B-trim: 1002 in 1/58 Lambda= 0.105682 statistics sampled from 29995 (30142) to 29995 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.353), width: 16 Scan time: 8.580 The best scores are: opt bits E(85289) NP_001273974 (OMIM: 609288) endophilin-B2 isoform ( 404) 2611 409.7 6.7e-114 XP_005252155 (OMIM: 609288) PREDICTED: endophilin- ( 400) 2558 401.6 1.8e-111 XP_006717254 (OMIM: 609288) PREDICTED: endophilin- ( 399) 2555 401.1 2.5e-111 NP_064530 (OMIM: 609288) endophilin-B2 isoform b [ ( 395) 1812 287.8 3.1e-77 NP_001273975 (OMIM: 609288) endophilin-B2 isoform ( 395) 1812 287.8 3.1e-77 XP_006710735 (OMIM: 609287) PREDICTED: endophilin- ( 402) 1577 252.0 1.9e-66 XP_006717253 (OMIM: 609288) PREDICTED: endophilin- ( 423) 1357 218.5 2.5e-56 XP_006717251 (OMIM: 609288) PREDICTED: endophilin- ( 428) 1357 218.5 2.5e-56 XP_005252157 (OMIM: 609288) PREDICTED: endophilin- ( 379) 1257 203.2 8.9e-52 XP_006717252 (OMIM: 609288) PREDICTED: endophilin- ( 424) 1254 202.8 1.3e-51 NP_001193580 (OMIM: 609287) endophilin-B1 isoform ( 394) 1228 198.8 2e-50 XP_016856898 (OMIM: 609287) PREDICTED: endophilin- ( 235) 917 151.2 2.4e-36 XP_011539840 (OMIM: 609287) PREDICTED: endophilin- ( 378) 910 150.3 7.5e-36 XP_016856899 (OMIM: 609287) PREDICTED: endophilin- ( 219) 901 148.8 1.2e-35 NP_001193581 (OMIM: 609287) endophilin-B1 isoform ( 386) 900 148.8 2.2e-35 NP_057093 (OMIM: 609287) endophilin-B1 isoform 1 [ ( 365) 897 148.3 2.9e-35 XP_005252158 (OMIM: 609288) PREDICTED: endophilin- ( 125) 782 130.5 2.3e-30 XP_006710736 (OMIM: 609287) PREDICTED: endophilin- ( 302) 767 128.4 2.3e-29 XP_016856897 (OMIM: 609287) PREDICTED: endophilin- ( 286) 415 74.7 3.1e-13 NP_001193582 (OMIM: 609287) endophilin-B1 isoform ( 265) 387 70.5 5.7e-12 NP_003016 (OMIM: 601768) endophilin-A2 isoform 1 [ ( 368) 293 56.2 1.5e-07 NP_003017 (OMIM: 604465) endophilin-A1 [Homo sapie ( 352) 281 54.4 5.2e-07 XP_016882635 (OMIM: 601768) PREDICTED: endophilin- ( 358) 281 54.4 5.3e-07 XP_011516307 (OMIM: 604465) PREDICTED: endophilin- ( 386) 265 52.0 3e-06 NP_003018 (OMIM: 603362) endophilin-A3 isoform a [ ( 347) 263 51.6 3.5e-06 NP_001311111 (OMIM: 603362) endophilin-A3 isoform ( 360) 263 51.6 3.6e-06 XP_011520191 (OMIM: 603362) PREDICTED: endophilin- ( 355) 251 49.8 1.2e-05 NP_001311112 (OMIM: 603362) endophilin-A3 isoform ( 355) 251 49.8 1.2e-05 NP_001288038 (OMIM: 603362) endophilin-A3 isoform ( 355) 251 49.8 1.2e-05 XP_011520194 (OMIM: 603362) PREDICTED: endophilin- ( 217) 239 47.8 3e-05 XP_011520193 (OMIM: 603362) PREDICTED: endophilin- ( 237) 239 47.9 3.2e-05 XP_011526485 (OMIM: 601768) PREDICTED: endophilin- ( 333) 224 45.7 0.00021 NP_001311113 (OMIM: 603362) endophilin-A3 isoform ( 312) 205 42.7 0.0015 NP_001311115 (OMIM: 603362) endophilin-A3 isoform ( 312) 205 42.7 0.0015 >>NP_001273974 (OMIM: 609288) endophilin-B2 isoform a [H (404 aa) initn: 2611 init1: 2611 opt: 2611 Z-score: 2165.9 bits: 409.7 E(85289): 6.7e-114 Smith-Waterman score: 2611; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 310 320 330 340 350 360 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: NP_001 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 370 380 390 400 >>XP_005252155 (OMIM: 609288) PREDICTED: endophilin-B2 i (400 aa) initn: 1390 init1: 1390 opt: 2558 Z-score: 2122.3 bits: 401.6 E(85289): 1.8e-111 Smith-Waterman score: 2558; 99.0% identity (99.0% similar) in 404 aa overlap (1-404:1-400) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAEAKAT----TVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 220 230 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 300 310 320 330 340 350 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: XP_005 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 400 >>XP_006717254 (OMIM: 609288) PREDICTED: endophilin-B2 i (399 aa) initn: 2562 init1: 1831 opt: 2555 Z-score: 2119.8 bits: 401.1 E(85289): 2.5e-111 Smith-Waterman score: 2555; 98.5% identity (98.5% similar) in 404 aa overlap (1-404:1-399) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP ::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_006 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGR-----FPGTFVGTTEP 250 260 270 280 290 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 300 310 320 330 340 350 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: XP_006 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 >>NP_064530 (OMIM: 609288) endophilin-B2 isoform b [Homo (395 aa) initn: 1922 init1: 1191 opt: 1812 Z-score: 1507.6 bits: 287.8 E(85289): 3.1e-77 Smith-Waterman score: 2502; 97.5% identity (97.5% similar) in 404 aa overlap (1-404:1-395) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 AAEAKAT----TVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 220 230 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP ::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_064 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGR-----FPGTFVGTTEP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 300 310 320 330 340 350 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: NP_064 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 >>NP_001273975 (OMIM: 609288) endophilin-B2 isoform b [H (395 aa) initn: 1922 init1: 1191 opt: 1812 Z-score: 1507.6 bits: 287.8 E(85289): 3.1e-77 Smith-Waterman score: 2502; 97.5% identity (97.5% similar) in 404 aa overlap (1-404:1-395) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAEAKAT----TVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 220 230 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP ::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGR-----FPGTFVGTTEP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 300 310 320 330 340 350 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: NP_001 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 360 370 380 390 >>XP_006710735 (OMIM: 609287) PREDICTED: endophilin-B1 i (402 aa) initn: 1601 init1: 892 opt: 1577 Z-score: 1313.9 bits: 252.0 E(85289): 1.9e-66 Smith-Waterman score: 1577; 60.6% identity (85.2% similar) in 411 aa overlap (1-404:4-402) 10 20 30 40 50 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKIL ::::.::::.::: :..:::::::::.:::::::::::.::::..:. :: :::::. XP_006 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD RQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIK .::::::::::.::.:::.:::::::.:::..: :::.::: ::..:.:: : ::..::: XP_006 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD VAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLK .:..:..:.:.:..:.:....::::::::.:::.:::.:::.::::.:::::: :.::: XP_006 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD KAKAAEAK------ATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTE ::::::.. : :::.. . . :. : .. .: .:: :.:::::..:.: XP_006 KAKAAETRNSQLNSARLEGDNIM-VNFSYMLNF-LHVKWLKIWAEEVTKSEQELRITQSE 190 200 210 220 230 240 250 260 270 280 290 pF1KSD FDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFP ::::::.::::::::::::..:::::..::..: :::::::..:::::::::: :: XP_006 FDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGS-----FP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD GTFVGTTEPAS-PPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKAR ........ .: :. :. :.. ... . : .. :.. : :.: ::.:::: XP_006 SNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD-LKEC----SGSRKAR 300 310 320 330 340 360 370 380 390 400 pF1KSD VLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::.::.:.::.:::::.:::.:. ::: :::.:::::.:::::.::::::. XP_006 VLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 350 360 370 380 390 400 >>XP_006717253 (OMIM: 609288) PREDICTED: endophilin-B2 i (423 aa) initn: 2548 init1: 1357 opt: 1357 Z-score: 1132.3 bits: 218.5 E(85289): 2.5e-56 Smith-Waterman score: 2497; 93.0% identity (93.0% similar) in 428 aa overlap (1-404:1-423) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASA------------------------LWND :::::::::::::::::::::::::::::::: :::: XP_006 AAEAKATCEGDTVPDFQETRPRNYILSASASAGTGSRVQLSSSPLPCWPLLLPSPQLWND 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD DLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL ::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLQKQLGR-----FPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL 310 320 330 340 350 340 350 360 370 380 390 pF1KSD EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP 360 370 380 390 400 410 400 pF1KSD VTYLELLS :::::::: XP_006 VTYLELLS 420 >>XP_006717251 (OMIM: 609288) PREDICTED: endophilin-B2 i (428 aa) initn: 2597 init1: 1357 opt: 1357 Z-score: 1132.2 bits: 218.5 E(85289): 2.5e-56 Smith-Waterman score: 2553; 94.4% identity (94.4% similar) in 428 aa overlap (1-404:1-428) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASA------------------------LWND :::::::::::::::::::::::::::::::: :::: XP_006 AAEAKATCEGDTVPDFQETRPRNYILSASASAGTGSRVQLSSSPLPCWPLLLPSPQLWND 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD DLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP 370 380 390 400 410 420 400 pF1KSD VTYLELLS :::::::: XP_006 VTYLELLS >>XP_005252157 (OMIM: 609288) PREDICTED: endophilin-B2 i (379 aa) initn: 1255 init1: 1255 opt: 1257 Z-score: 1050.6 bits: 203.2 E(85289): 8.9e-52 Smith-Waterman score: 2383; 93.8% identity (93.8% similar) in 404 aa overlap (1-404:1-379) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTR ::::::: :::::::::::::::::::::::::::: XP_005 AAEAKAT-------------------------LWNDEVDKAEQELRVAQTEFDRQAEVTR 190 200 210 250 260 270 280 290 300 pF1KSD LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADS 280 290 300 310 320 330 370 380 390 400 pF1KSD SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS :::::::::::::::::::::::::::::::::::::::::::: XP_005 SELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 340 350 360 370 >>XP_006717252 (OMIM: 609288) PREDICTED: endophilin-B2 i (424 aa) initn: 2431 init1: 1254 opt: 1254 Z-score: 1047.4 bits: 202.8 E(85289): 1.3e-51 Smith-Waterman score: 2500; 93.5% identity (93.5% similar) in 428 aa overlap (1-404:1-424) 10 20 30 40 50 60 pF1KSD MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 130 140 150 160 170 180 190 200 210 pF1KSD AAEAKATCEGDTVPDFQETRPRNYILSASASA------------------------LWND ::::::: ::::::::::::::::::::: :::: XP_006 AAEAKAT----TVPDFQETRPRNYILSASASAGTGSRVQLSSSPLPCWPLLLPSPQLWND 190 200 210 220 230 220 230 240 250 260 270 pF1KSD EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHML 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD DLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCL 300 310 320 330 340 350 340 350 360 370 380 390 pF1KSD EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVP 360 370 380 390 400 410 400 pF1KSD VTYLELLS :::::::: XP_006 VTYLELLS 420 404 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:29:18 2016 done: Thu Nov 3 07:29:19 2016 Total Scan time: 8.580 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]