FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1882, 1148 aa 1>>>pF1KSDA1882 1148 - 1148 aa - 1148 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7197+/-0.000401; mu= 20.2080+/- 0.025 mean_var=77.0101+/-15.473, 0's: 0 Z-trim(111.6): 15 B-trim: 0 in 0/55 Lambda= 0.146151 statistics sampled from 20182 (20190) to 20182 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.237), width: 16 Scan time: 16.060 The best scores are: opt bits E(85289) NP_001153844 (OMIM: 611966,613192) trafficking pro (1148) 7665 1626.7 0 NP_113654 (OMIM: 611966,613192) trafficking protei (1246) 7665 1626.7 0 XP_011515630 (OMIM: 611966,613192) PREDICTED: traf (1128) 6762 1436.3 0 XP_016869382 (OMIM: 611966,613192) PREDICTED: traf ( 989) 5667 1205.3 0 NP_001308575 (OMIM: 611966,613192) trafficking pro (1139) 5652 1202.2 0 XP_011515628 (OMIM: 611966,613192) PREDICTED: traf (1237) 5652 1202.2 0 XP_016869383 (OMIM: 611966,613192) PREDICTED: traf ( 688) 4567 973.3 0 XP_011515632 (OMIM: 611966,613192) PREDICTED: traf ( 631) 4197 895.3 0 >>NP_001153844 (OMIM: 611966,613192) trafficking protein (1148 aa) initn: 7665 init1: 7665 opt: 7665 Z-score: 8726.8 bits: 1626.7 E(85289): 0 Smith-Waterman score: 7665; 100.0% identity (100.0% similar) in 1148 aa overlap (1-1148:1-1148) 10 20 30 40 50 60 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRICSVSQISVRDSQRVLYIRYRHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRICSVSQISVRDSQRVLYIRYRHH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YPPENNEWGDFQTHRKVVGLITITDCFSAKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPPENNEWGDFQTHRKVVGLITITDCFSAKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QGEIVEQPRTDVAFYPNYEDCQTVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGEIVEQPRTDVAFYPNYEDCQTVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WLGAALEGLCSASVIYHYPGGTGGKSGARRFQGSTLPAEAANRHRPGAQEVLIDPGALTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLGAALEGLCSASVIYHYPGGTGGKSGARRFQGSTLPAEAANRHRPGAQEVLIDPGALTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACIKAVRVLAIQKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACIKAVRVLAIQKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AEPGWRACYKLLLETLPGYSLSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEPGWRACYKLLLETLPGYSLSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VRHLSFLLQTMLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRHLSFLLQTMLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RHVKLLNLPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHVKLLNLPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GYHTTVFGVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYHTTVFGVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEIST 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NVSVQLYNGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVSVQLYNGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QPGKVATFTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPGKVATFTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ESNKAGDYSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESNKAGDYSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD TRQCHLLLDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRQCHLLLDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD ANPKQLEEERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANPKQLEEERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LVDGQPCDREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVDGQPCDREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD VSFVGSSTFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSFVGSSTFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVH 1090 1100 1110 1120 1130 1140 pF1KSD VCALEAQA :::::::: NP_001 VCALEAQA >>NP_113654 (OMIM: 611966,613192) trafficking protein pa (1246 aa) initn: 7665 init1: 7665 opt: 7665 Z-score: 8726.3 bits: 1626.7 E(85289): 0 Smith-Waterman score: 7665; 100.0% identity (100.0% similar) in 1148 aa overlap (1-1148:99-1246) 10 20 30 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEEN :::::::::::::::::::::::::::::: NP_113 PQWASAGPPPLSFTEEVKFELRALKDWDFKMSVPDYMQCAEDHQTLLVVVQPVGIVSEEN 70 80 90 100 110 120 40 50 60 70 80 90 pF1KSD FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK 130 140 150 160 170 180 100 110 120 130 140 150 pF1KSD DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED 190 200 210 220 230 240 160 170 180 190 200 210 pF1KSD FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG 250 260 270 280 290 300 220 230 240 250 260 270 pF1KSD DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR 310 320 330 340 350 360 280 290 300 310 320 330 pF1KSD FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA 370 380 390 400 410 420 340 350 360 370 380 390 pF1KSD ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI 430 440 450 460 470 480 400 410 420 430 440 450 pF1KSD LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR 490 500 510 520 530 540 460 470 480 490 500 510 pF1KSD GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY 550 560 570 580 590 600 520 530 540 550 560 570 pF1KSD TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP 610 620 630 640 650 660 580 590 600 610 620 630 pF1KSD FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL 670 680 690 700 710 720 640 650 660 670 680 690 pF1KSD PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV 730 740 750 760 770 780 700 710 720 730 740 750 pF1KSD IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE 790 800 810 820 830 840 760 770 780 790 800 810 pF1KSD VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD 850 860 870 880 890 900 820 830 840 850 860 870 pF1KSD DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE 910 920 930 940 950 960 880 890 900 910 920 930 pF1KSD GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL 970 980 990 1000 1010 1020 940 950 960 970 980 990 pF1KSD HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS 1030 1040 1050 1060 1070 1080 1000 1010 1020 1030 1040 1050 pF1KSD LKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNR 1090 1100 1110 1120 1130 1140 1060 1070 1080 1090 1100 1110 pF1KSD SPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFYLDAVQPSGQSACLGALLFLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 SPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFYLDAVQPSGQSACLGALLFLY 1150 1160 1170 1180 1190 1200 1120 1130 1140 pF1KSD TGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA :::::::::::::::::::::::::::::::::::::: NP_113 TGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA 1210 1220 1230 1240 >>XP_011515630 (OMIM: 611966,613192) PREDICTED: traffick (1128 aa) initn: 6762 init1: 6762 opt: 6762 Z-score: 7697.9 bits: 1436.3 E(85289): 0 Smith-Waterman score: 6762; 100.0% identity (100.0% similar) in 1018 aa overlap (1-1018:99-1116) 10 20 30 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEEN :::::::::::::::::::::::::::::: XP_011 PQWASAGPPPLSFTEEVKFELRALKDWDFKMSVPDYMQCAEDHQTLLVVVQPVGIVSEEN 70 80 90 100 110 120 40 50 60 70 80 90 pF1KSD FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK 130 140 150 160 170 180 100 110 120 130 140 150 pF1KSD DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED 190 200 210 220 230 240 160 170 180 190 200 210 pF1KSD FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG 250 260 270 280 290 300 220 230 240 250 260 270 pF1KSD DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR 310 320 330 340 350 360 280 290 300 310 320 330 pF1KSD FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA 370 380 390 400 410 420 340 350 360 370 380 390 pF1KSD ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI 430 440 450 460 470 480 400 410 420 430 440 450 pF1KSD LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR 490 500 510 520 530 540 460 470 480 490 500 510 pF1KSD GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY 550 560 570 580 590 600 520 530 540 550 560 570 pF1KSD TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP 610 620 630 640 650 660 580 590 600 610 620 630 pF1KSD FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL 670 680 690 700 710 720 640 650 660 670 680 690 pF1KSD PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV 730 740 750 760 770 780 700 710 720 730 740 750 pF1KSD IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE 790 800 810 820 830 840 760 770 780 790 800 810 pF1KSD VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD 850 860 870 880 890 900 820 830 840 850 860 870 pF1KSD DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE 910 920 930 940 950 960 880 890 900 910 920 930 pF1KSD GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL 970 980 990 1000 1010 1020 940 950 960 970 980 990 pF1KSD HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS 1030 1040 1050 1060 1070 1080 1000 1010 1020 1030 1040 1050 pF1KSD LKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNR :::::::::::::::::::::::::::: XP_011 LKRSGEASVEGLLNQLVLEHLQLAPLQWGGQLSTPVTVQT 1090 1100 1110 1120 >>XP_016869382 (OMIM: 611966,613192) PREDICTED: traffick (989 aa) initn: 5663 init1: 5663 opt: 5667 Z-score: 6451.0 bits: 1205.3 E(85289): 0 Smith-Waterman score: 5667; 99.2% identity (99.5% similar) in 861 aa overlap (1-861:99-959) 10 20 30 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEEN :::::::::::::::::::::::::::::: XP_016 PQWASAGPPPLSFTEEVKFELRALKDWDFKMSVPDYMQCAEDHQTLLVVVQPVGIVSEEN 70 80 90 100 110 120 40 50 60 70 80 90 pF1KSD FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK 130 140 150 160 170 180 100 110 120 130 140 150 pF1KSD DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED 190 200 210 220 230 240 160 170 180 190 200 210 pF1KSD FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG 250 260 270 280 290 300 220 230 240 250 260 270 pF1KSD DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR 310 320 330 340 350 360 280 290 300 310 320 330 pF1KSD FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA 370 380 390 400 410 420 340 350 360 370 380 390 pF1KSD ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI 430 440 450 460 470 480 400 410 420 430 440 450 pF1KSD LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR 490 500 510 520 530 540 460 470 480 490 500 510 pF1KSD GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY 550 560 570 580 590 600 520 530 540 550 560 570 pF1KSD TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP 610 620 630 640 650 660 580 590 600 610 620 630 pF1KSD FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL 670 680 690 700 710 720 640 650 660 670 680 690 pF1KSD PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV 730 740 750 760 770 780 700 710 720 730 740 750 pF1KSD IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE 790 800 810 820 830 840 760 770 780 790 800 810 pF1KSD VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD 850 860 870 880 890 900 820 830 840 850 860 870 pF1KSD DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE :::::::::::::::::::::::::::::::::::::::::: : . ..: XP_016 DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKENENTDSLKDMTDAHSSF 910 920 930 940 950 960 880 890 900 910 920 930 pF1KSD GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL XP_016 IHNSPKLETKCPGTDEWINTL 970 980 >>NP_001308575 (OMIM: 611966,613192) trafficking protein (1139 aa) initn: 5652 init1: 5652 opt: 5652 Z-score: 6433.0 bits: 1202.2 E(85289): 0 Smith-Waterman score: 7578; 99.2% identity (99.2% similar) in 1148 aa overlap (1-1148:1-1139) 10 20 30 40 50 60 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRICSVSQISVRDSQRVLYIRYRHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRICSVSQISVRDSQRVLYIRYRHH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YPPENNEWGDFQTHRKVVGLITITDCFSAKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPPENNEWGDFQTHRKVVGLITITDCFSAKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QGEIVEQPRTDVAFYPNYEDCQTVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGEIVEQPRTDVAFYPNYEDCQTVEKRIEDFIESLFIVLESKRLDRATDKSGDKIPLLCV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WLGAALEGLCSASVIYHYPGGTGGKSGARRFQGSTLPAEAANRHRPGAQEVLIDPGALTT :::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_001 WLGAALEGLCSASVIYHYPGGTGGKSGARRFQGSTLPAEAANRHRPGA---------LTT 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACIKAVRVLAIQKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGINPDTSTEIGRAKNCLSPEDIIDKYKEAISYYSKYKNAGVIELEACIKAVRVLAIQKR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD SMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD AEPGWRACYKLLLETLPGYSLSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEPGWRACYKLLLETLPGYSLSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD VRHLSFLLQTMLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRHLSFLLQTMLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RHVKLLNLPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHVKLLNLPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCE 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD VQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVN 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD GYHTTVFGVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYHTTVFGVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEIST 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD NVSVQLYNGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVSVQLYNGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPL 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD QPGKVATFTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPGKVATFTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD ESNKAGDYSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESNKAGDYSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATS 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD TRQCHLLLDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRQCHLLLDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQF 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD ANPKQLEEERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANPKQLEEERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDV 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LVDGQPCDREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVDGQPCDREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDT 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KSD VSFVGSSTFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSFVGSSTFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVH 1080 1090 1100 1110 1120 1130 pF1KSD VCALEAQA :::::::: NP_001 VCALEAQA >>XP_011515628 (OMIM: 611966,613192) PREDICTED: traffick (1237 aa) initn: 5652 init1: 5652 opt: 5652 Z-score: 6432.4 bits: 1202.2 E(85289): 0 Smith-Waterman score: 7578; 99.2% identity (99.2% similar) in 1148 aa overlap (1-1148:99-1237) 10 20 30 pF1KSD MSVPDYMQCAEDHQTLLVVVQPVGIVSEEN :::::::::::::::::::::::::::::: XP_011 PQWASAGPPPLSFTEEVKFELRALKDWDFKMSVPDYMQCAEDHQTLLVVVQPVGIVSEEN 70 80 90 100 110 120 40 50 60 70 80 90 pF1KSD FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFRIYKRICSVSQISVRDSQRVLYIRYRHHYPPENNEWGDFQTHRKVVGLITITDCFSAK 130 140 150 160 170 180 100 110 120 130 140 150 pF1KSD DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQGEIVEQPRTDVAFYPNYEDCQTVEKRIED 190 200 210 220 230 240 160 170 180 190 200 210 pF1KSD FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVG 250 260 270 280 290 300 220 230 240 250 260 270 pF1KSD DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKSGARR 310 320 330 340 350 360 280 290 300 310 320 330 pF1KSD FQGSTLPAEAANRHRPGAQEVLIDPGALTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA :::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 FQGSTLPAEAANRHRPGA---------LTTNGINPDTSTEIGRAKNCLSPEDIIDKYKEA 370 380 390 400 410 340 350 360 370 380 390 pF1KSD ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISYYSKYKNAGVIELEACIKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSI 420 430 440 450 460 470 400 410 420 430 440 450 pF1KSD LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGYSLSLDPKDFSR 480 490 500 510 520 530 460 470 480 490 500 510 pF1KSD GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVAQSLENY 540 550 560 570 580 590 520 530 540 550 560 570 pF1KSD TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPASLRPHKMKSLLGQNVSTKSP 600 610 620 630 640 650 580 590 600 610 620 630 pF1KSD FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESL 660 670 680 690 700 710 640 650 660 670 680 690 pF1KSD PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVFSDCLLDNLPGIKTSGSTVEV 720 730 740 750 760 770 700 710 720 730 740 750 pF1KSD IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGESQQLIIKLENIGMEPLEKLE 780 790 800 810 820 830 760 770 780 790 800 810 pF1KSD VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTINIKVKLDFSCQENLLQDLSD 840 850 860 870 880 890 820 830 840 850 860 870 pF1KSD DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSHVKTLEAVLNFKYSGGPGHTE 900 910 920 930 940 950 880 890 900 910 920 930 pF1KSD GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNSTEHELTVSTRSSEALIL 960 970 980 990 1000 1010 940 950 960 970 980 990 pF1KSD HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEERREARGLEIHSKLGICWRIPS 1020 1030 1040 1050 1060 1070 1000 1010 1020 1030 1040 1050 pF1KSD LKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDREAVAACQVGDPVRLEVRLTNR 1080 1090 1100 1110 1120 1130 1060 1070 1080 1090 1100 1110 pF1KSD SPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFYLDAVQPSGQSACLGALLFLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFYLDAVQPSGQSACLGALLFLY 1140 1150 1160 1170 1180 1190 1120 1130 1140 pF1KSD TGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA :::::::::::::::::::::::::::::::::::::: XP_011 TGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA 1200 1210 1220 1230 >>XP_016869383 (OMIM: 611966,613192) PREDICTED: traffick (688 aa) initn: 4567 init1: 4567 opt: 4567 Z-score: 5199.9 bits: 973.3 E(85289): 0 Smith-Waterman score: 4567; 100.0% identity (100.0% similar) in 688 aa overlap (461-1148:1-688) 440 450 460 470 480 490 pF1KSD LLLETLPGYSLSLDPKDFSRGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQT :::::::::::::::::::::::::::::: XP_016 MRLLHELVYASRRMGNPALSVRHLSFLLQT 10 20 30 500 510 520 530 540 550 pF1KSD MLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLNLPA 40 50 60 70 80 90 560 570 580 590 600 610 pF1KSD SLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYNPMP 100 110 120 130 140 150 620 630 640 650 660 670 pF1KSD FELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVFGVF 160 170 180 190 200 210 680 690 700 710 720 730 pF1KSD SDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLYNGE 220 230 240 250 260 270 740 750 760 770 780 790 pF1KSD SQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVATFTI 280 290 300 310 320 330 800 810 820 830 840 850 pF1KSD NIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGDYSH 340 350 360 370 380 390 860 870 880 890 900 910 pF1KSD VKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDV 400 410 420 430 440 450 920 930 940 950 960 970 pF1KSD FNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLEEER 460 470 480 490 500 510 980 990 1000 1010 1020 1030 pF1KSD REARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPCDRE 520 530 540 550 560 570 1040 1050 1060 1070 1080 1090 pF1KSD AVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSSTFY 580 590 600 610 620 630 1100 1110 1120 1130 1140 pF1KSD LDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQA 640 650 660 670 680 >>XP_011515632 (OMIM: 611966,613192) PREDICTED: traffick (631 aa) initn: 4197 init1: 4197 opt: 4197 Z-score: 4778.8 bits: 895.3 E(85289): 0 Smith-Waterman score: 4197; 100.0% identity (100.0% similar) in 631 aa overlap (518-1148:1-631) 490 500 510 520 530 540 pF1KSD LQTMLDFLSDQEKKDVAQSLENYTSKCPGTMEPIALPGGLTLPPVPFTKLPIVRHVKLLN :::::::::::::::::::::::::::::: XP_011 MEPIALPGGLTLPPVPFTKLPIVRHVKLLN 10 20 30 550 560 570 580 590 600 pF1KSD LPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPASLRPHKMKSLLGQNVSTKSPFIYSPIIAHNRGEERNKKIDFQWVQGDVCEVQLMVYN 40 50 60 70 80 90 610 620 630 640 650 660 pF1KSD PMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVNGYHTTVF 100 110 120 130 140 150 670 680 690 700 710 720 pF1KSD GVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVFSDCLLDNLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDEISTNVSVQLY 160 170 180 190 200 210 730 740 750 760 770 780 pF1KSD NGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGESQQLIIKLENIGMEPLEKLEVTSKVLTTKEKLYGDFLSWKLEETLAQFPLQPGKVAT 220 230 240 250 260 270 790 800 810 820 830 840 pF1KSD FTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTINIKVKLDFSCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVEGKPVNPPESNKAGD 280 290 300 310 320 330 850 860 870 880 890 900 pF1KSD YSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSHVKTLEAVLNFKYSGGPGHTEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLL 340 350 360 370 380 390 910 920 930 940 950 960 pF1KSD LDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDVFNSTEHELTVSTRSSEALILHAGECQRMAIQVDKFNFESFPESPGEKGQFANPKQLE 400 410 420 430 440 450 970 980 990 1000 1010 1020 pF1KSD EERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EERREARGLEIHSKLGICWRIPSLKRSGEASVEGLLNQLVLEHLQLAPLQWDVLVDGQPC 460 470 480 490 500 510 1030 1040 1050 1060 1070 1080 pF1KSD DREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DREAVAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDTVSFVGSS 520 530 540 550 560 570 1090 1100 1110 1120 1130 1140 pF1KSD TFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFYLDAVQPSGQSACLGALLFLYTGDFFLHIRFHEDSTSKELPPSWFCLPSVHVCALEAQ 580 590 600 610 620 630 pF1KSD A : XP_011 A 1148 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:35:48 2016 done: Thu Nov 3 07:35:50 2016 Total Scan time: 16.060 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]