FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1892, 453 aa
  1>>>pF1KSDA1892 453 - 453 aa - 453 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8640+/-0.000852; mu= 14.3541+/- 0.051
 mean_var=74.3194+/-15.212, 0's: 0 Z-trim(106.8): 37  B-trim: 2 in 1/50
 Lambda= 0.148773
 statistics sampled from 9163 (9189) to 9163 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.282), width:  16
 Scan time:  3.050

The best scores are:                                      opt bits E(32554)
CCDS6549.1 DCAF12 gene_id:25853|Hs108|chr9         ( 453) 3099 674.7 5.3e-194
CCDS43991.1 DCAF12L2 gene_id:340578|Hs108|chrX     ( 463) 1944 426.8 2.3e-119
CCDS14610.1 DCAF12L1 gene_id:139170|Hs108|chrX     ( 463) 1844 405.3 6.6e-113


>>CCDS6549.1 DCAF12 gene_id:25853|Hs108|chr9              (453 aa)
 initn: 3099 init1: 3099 opt: 3099  Z-score: 3596.4  bits: 674.7 E(32554): 5.3e-194
Smith-Waterman score: 3099; 100.0% identity (100.0% similar) in 453 aa overlap (1-453:1-453)

               10        20        30        40        50        60
pF1KSD MARKVVSRKRKAPASPGAGSDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVRLQNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 MARKVVSRKRKAPASPGAGSDAQGPQFGWDHSLHKRKRLPPVKRSLVYYLKNREVRLQNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD TSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 TSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTLFVVDVQTS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD QITKIPILKDREPGGVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 QITKIPILKDREPGGVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLPTLDPVCVGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVPVYAHITHKAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 KDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLSTKLPYCRENV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEHIITVGTGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 CLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYEHIITVGTGQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYFSDIDFFPNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 SLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNYFSDIDFFPNA
              370       380       390       400       410       420

              430       440       450   
pF1KSD VYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS
       :::::::::::::::::::::::::::::::::
CCDS65 VYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS
              430       440       450   

>>CCDS43991.1 DCAF12L2 gene_id:340578|Hs108|chrX          (463 aa)
 initn: 1979 init1: 1285 opt: 1944  Z-score: 2256.5  bits: 426.8 E(32554): 2.3e-119
Smith-Waterman score: 1977; 64.9% identity (84.2% similar) in 456 aa overlap (7-453:8-463)

                10         20           30        40        50     
pF1KSD  MARKVVSRKRKAPA-SPGAGSDA-QG--PQFGWDHSLHKRKRLPPVKRSLVYYLKNREV
              ::::::::   ::::.. ::     :    : :... : ..: ::.:::.:::
CCDS43 MAQQQTGSRKRKAPAVEAGAGSSSSQGLAAADGEGPLLPKKQKRPATRRRLVHYLKGREV
               10        20        30        40        50        60

          60           70        80        90       100       110  
pF1KSD RLQNETS---YSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQVVCGTKCNTL
         .. ..   .   :.:::.:.:: :: ::.. :::::::::::::: ::::::::::::
CCDS43 GARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTL
               70        80        90       100       110       120

            120       130        140       150       160       170 
pF1KSD FVVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNPNSLAIYRLP
       ::::::...::.::...:.: : . ..:::::::::::::.:::::::.::::::::.::
CCDS43 FVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLP
              130       140       150       160       170       180

             180        190       200       210       220       230
pF1KSD TLDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSDARHNVSRVP
       ::::.:.::  :::::::..::.:::.::::::::...::..  :... : : :.   .:
CCDS43 TLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLP
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KSD VYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKAENTLSKLLS
       :::::  . .. ::. .:::.: :::::::..::.::::::::::::::::..:::.:::
CCDS43 VYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLS
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KSD TKLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGSGIRSVSFYE
        .::::::::::.: .: :.::::::.::::::::: . :.. .:::: :.:.::.:::.
CCDS43 IRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQ
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KSD HIITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWLNHDETWRNY
       ::::::::.:::::::::::.::::: :.   : :  ::..:::. :.::::.:..: ::
CCDS43 HIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNY
              370       380       390       400       410       420

              420       430       440       450   
pF1KSD FSDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS
       :. .  ::::.:::::.    ::::::::::::::::::::::
CCDS43 FGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS
              430       440       450       460   

>>CCDS14610.1 DCAF12L1 gene_id:139170|Hs108|chrX          (463 aa)
 initn: 1871 init1: 1197 opt: 1844  Z-score: 2140.5  bits: 405.3 E(32554): 6.6e-113
Smith-Waterman score: 1860; 61.3% identity (80.4% similar) in 465 aa overlap (7-453:8-463)

                10                  20        30        40         
pF1KSD  MARKVVSRKRKAPA-------SPGAG---SDAQGPQFGWDHSLHKRKRLPPVKRSLVYY
              ::::::::       ::. :   .:..::       : ::.: : . ::...:
CCDS14 MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPL------LLKRQRRPATYRSMAHY
               10        20        30              40        50    

      50              60        70        80        90       100   
pF1KSD LKNREV------RLQNETSYSRVLHGYAAQQLPSLLKEREFHLGTLNKVFASQWLNHRQV
       :: :::      :::   ...  :.:::.:.:: :: ::...:::.:::::::::: :::
CCDS14 LKVREVGGWGPARLQ---GFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQV
           60           70        80        90       100       110 

           110       120       130        140       150       160  
pF1KSD VCGTKCNTLFVVDVQTSQITKIPILKDREPG-GVTQQGCGIHAIELNPSRTLLATGGDNP
       ::::::::::::::....:..::.:.: :   .  ::::::::::::::.:::::::.::
CCDS14 VCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENP
             120       130       140       150       160       170 

            170       180        190       200       210       220 
pF1KSD NSLAIYRLPTLDPVCVGD-DGHKDWIFSIAWISDTMAVSGSRDGSMGLWEVTDDVLTKSD
       ::::::.::.:::.:.::  :::::::..::.:::.::::::::...::..  : .  . 
CCDS14 NSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTV
             180       190       200       210       220       230 

             230       240       250       260       270       280 
pF1KSD ARHNVSRVPVYAHITHKALKDIPKEDTNPDNCKVRALAFNNKNKELGAVSLDGYFHLWKA
       : :.   .::::::  . .. ::.   ::.: :::::: ..::.::::::::::::::::
CCDS14 AWHSEVGLPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKA
             240       250       260       270       280       290 

             290       300       310       320       330       340 
pF1KSD ENTLSKLLSTKLPYCRENVCLAYGSEWSVYAVGSQAHVSFLDPRQPSYNVKSVCSRERGS
        ..::.::: .::: :.::::.: .. :::::::..:::::: :: . :.. .:::: :.
CCDS14 GSALSRLLSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGT
             300       310       320       330       340       350 

             350       360       370       380       390       400 
pF1KSD GIRSVSFYEHIITVGTGQGSLLFYDIRAQRFLEERLSACYGSKPRLAGENLKLTTGKGWL
       :.::.:::.::::::::::::::::.:::.::::: ::   :.   : ..:.:. :.:::
CCDS14 GVRSLSFYRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWL
             360       370       380       390       400       410 

             410       420       430       440       450   
pF1KSD NHDETWRNYFSDIDFFPNAVYTHCYDSSGTKLFVAGGPLPSGLHGNYAGLWS
       ::.. : :::. .. ::::.:::::.    ::::::::::.:::::::::::
CCDS14 NHNDFWVNYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS
             420       430       440       450       460   




453 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:38:04 2016 done: Thu Nov  3 07:38:05 2016
 Total Scan time:  3.050 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]