FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1896, 501 aa 1>>>pF1KSDA1896 501 - 501 aa - 501 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9122+/-0.000544; mu= 21.4088+/- 0.034 mean_var=103.1580+/-20.634, 0's: 0 Z-trim(111.0): 266 B-trim: 716 in 2/54 Lambda= 0.126277 statistics sampled from 19186 (19488) to 19186 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.228), width: 16 Scan time: 9.320 The best scores are: opt bits E(85289) NP_001252543 (OMIM: 608745) calcium-binding mitoch ( 501) 3349 621.6 1.7e-177 XP_006717011 (OMIM: 608745) PREDICTED: calcium-bin ( 481) 2841 529.0 1.2e-149 NP_001317917 (OMIM: 608745) calcium-binding mitoch ( 515) 2834 527.7 3e-149 XP_006717012 (OMIM: 608745) PREDICTED: calcium-bin ( 378) 2502 467.1 4e-131 XP_005251746 (OMIM: 608745) PREDICTED: calcium-bin ( 366) 2275 425.7 1.1e-118 NP_443133 (OMIM: 608745) calcium-binding mitochond ( 469) 2275 425.9 1.3e-118 NP_001006643 (OMIM: 608745) calcium-binding mitoch ( 489) 2275 425.9 1.3e-118 NP_001006642 (OMIM: 608745) calcium-binding mitoch ( 503) 2275 425.9 1.3e-118 NP_077008 (OMIM: 608746) calcium-binding mitochond ( 468) 1758 331.7 2.9e-90 XP_011526577 (OMIM: 608746) PREDICTED: calcium-bin ( 577) 1758 331.8 3.3e-90 NP_037518 (OMIM: 608744) calcium-binding mitochond ( 477) 1636 309.5 1.4e-83 NP_998816 (OMIM: 608744) calcium-binding mitochond ( 458) 1628 308.0 3.8e-83 XP_011526583 (OMIM: 608746) PREDICTED: calcium-bin ( 515) 1610 304.8 4e-82 XP_011526580 (OMIM: 608746) PREDICTED: calcium-bin ( 549) 1610 304.8 4.2e-82 XP_011526579 (OMIM: 608746) PREDICTED: calcium-bin ( 560) 1610 304.8 4.2e-82 XP_011526576 (OMIM: 608746) PREDICTED: calcium-bin ( 624) 1610 304.9 4.5e-82 XP_016882774 (OMIM: 608746) PREDICTED: calcium-bin ( 562) 1603 303.5 1e-81 XP_016882777 (OMIM: 608746) PREDICTED: calcium-bin ( 484) 1473 279.8 1.3e-74 XP_011526586 (OMIM: 608746) PREDICTED: calcium-bin ( 469) 1331 253.9 7.5e-67 XP_011526584 (OMIM: 608746) PREDICTED: calcium-bin ( 503) 1330 253.7 8.9e-67 XP_011526585 (OMIM: 608746) PREDICTED: calcium-bin ( 490) 1325 252.8 1.6e-66 XP_011526582 (OMIM: 608746) PREDICTED: calcium-bin ( 531) 1325 252.9 1.7e-66 XP_016856593 (OMIM: 608744) PREDICTED: calcium-bin ( 271) 1178 225.7 1.3e-58 XP_011526228 (OMIM: 610822) PREDICTED: solute carr ( 306) 1093 210.3 6.5e-54 NP_775908 (OMIM: 610822) solute carrier family 25 ( 370) 1093 210.4 7.3e-54 NP_001308227 (OMIM: 610822) solute carrier family ( 232) 893 173.7 5.1e-43 XP_016882781 (OMIM: 608746) PREDICTED: calcium-bin ( 366) 892 173.8 7.7e-43 XP_016882779 (OMIM: 608746) PREDICTED: calcium-bin ( 412) 892 173.8 8.3e-43 XP_016882775 (OMIM: 608746) PREDICTED: calcium-bin ( 521) 892 174.0 9.6e-43 XP_016882780 (OMIM: 608746) PREDICTED: calcium-bin ( 376) 878 171.2 4.6e-42 XP_016882776 (OMIM: 608746) PREDICTED: calcium-bin ( 485) 878 171.4 5.4e-42 XP_011526587 (OMIM: 608746) PREDICTED: calcium-bin ( 459) 744 146.9 1.2e-34 XP_011526578 (OMIM: 608746) PREDICTED: calcium-bin ( 568) 744 147.0 1.3e-34 XP_016882778 (OMIM: 608746) PREDICTED: calcium-bin ( 423) 682 135.6 2.8e-31 XP_011526581 (OMIM: 608746) PREDICTED: calcium-bin ( 532) 682 135.7 3.2e-31 XP_011526239 (OMIM: 610823) PREDICTED: mitochondri ( 318) 602 120.9 5.6e-27 NP_001308473 (OMIM: 610823) mitochondrial coenzyme ( 318) 602 120.9 5.6e-27 NP_848621 (OMIM: 610823) mitochondrial coenzyme A ( 318) 602 120.9 5.6e-27 XP_005259918 (OMIM: 610823) PREDICTED: mitochondri ( 318) 602 120.9 5.6e-27 XP_016882159 (OMIM: 610823) PREDICTED: mitochondri ( 382) 602 121.0 6.3e-27 NP_001311242 (OMIM: 139080) graves disease carrier ( 281) 462 95.3 2.5e-19 NP_001311241 (OMIM: 139080) graves disease carrier ( 315) 462 95.3 2.7e-19 NP_689920 (OMIM: 139080) graves disease carrier pr ( 332) 462 95.4 2.8e-19 XP_011538513 (OMIM: 139080) PREDICTED: graves dise ( 332) 462 95.4 2.8e-19 NP_660348 (OMIM: 300641) solute carrier family 25 ( 341) 439 91.2 5.1e-18 NP_001269125 (OMIM: 300242) brain mitochondrial ca ( 322) 384 81.2 5.1e-15 NP_001269124 (OMIM: 300242) brain mitochondrial ca ( 325) 384 81.2 5.2e-15 XP_011529704 (OMIM: 300242) PREDICTED: brain mitoc ( 334) 384 81.2 5.2e-15 NP_001269127 (OMIM: 300242) brain mitochondrial ca ( 290) 375 79.5 1.5e-14 XP_016885428 (OMIM: 300242) PREDICTED: brain mitoc ( 338) 362 77.2 8.5e-14 >>NP_001252543 (OMIM: 608745) calcium-binding mitochondr (501 aa) initn: 3349 init1: 3349 opt: 3349 Z-score: 3307.7 bits: 621.6 E(85289): 1.7e-177 Smith-Waterman score: 3349; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501) 10 20 30 40 50 60 pF1KSD MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFLGKQDGRAEATEKRPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFLGKQDGRAEATEKRPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD REGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIP 430 440 450 460 470 480 490 500 pF1KSD AVSISYVVYENLKITLGVQSR ::::::::::::::::::::: NP_001 AVSISYVVYENLKITLGVQSR 490 500 >>XP_006717011 (OMIM: 608745) PREDICTED: calcium-binding (481 aa) initn: 2841 init1: 2841 opt: 2841 Z-score: 2807.7 bits: 529.0 E(85289): 1.2e-149 Smith-Waterman score: 2841; 99.3% identity (99.8% similar) in 432 aa overlap (70-501:50-481) 40 50 60 70 80 90 pF1KSD QMASFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDH :. .:::::::::::::::::::::::::: XP_006 YFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDH 20 30 40 50 60 70 100 110 120 130 140 150 pF1KSD EKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMD 80 90 100 110 120 130 160 170 180 190 200 210 pF1KSD KNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWW 140 150 160 170 180 190 220 230 240 250 260 270 pF1KSD RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 200 210 220 230 240 250 280 290 300 310 320 330 pF1KSD INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 260 270 280 290 300 310 340 350 360 370 380 390 pF1KSD MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 320 330 340 350 360 370 400 410 420 430 440 450 pF1KSD YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 380 390 400 410 420 430 460 470 480 490 500 pF1KSD RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR :::::::::::::::::::::::::::::::::::::::::: XP_006 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 440 450 460 470 480 >>NP_001317917 (OMIM: 608745) calcium-binding mitochondr (515 aa) initn: 2834 init1: 2834 opt: 2834 Z-score: 2800.5 bits: 527.7 E(85289): 3e-149 Smith-Waterman score: 2834; 99.8% identity (100.0% similar) in 429 aa overlap (73-501:87-515) 50 60 70 80 90 100 pF1KSD SFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKK .::::::::::::::::::::::::::::: NP_001 LDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD LRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNG 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD TMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL 300 310 320 330 340 350 350 360 370 380 390 400 pF1KSD RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 420 430 440 450 460 470 470 480 490 500 pF1KSD GAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR ::::::::::::::::::::::::::::::::::::::: NP_001 GAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 480 490 500 510 >>XP_006717012 (OMIM: 608745) PREDICTED: calcium-binding (378 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 2475.1 bits: 467.1 E(85289): 4e-131 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 378 aa overlap (124-501:1-378) 100 110 120 130 140 150 pF1KSD HYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWG :::::::::::::::::::::::::::::: XP_006 MQSLRDLGVKISEQQAEKILKRIRTGHFWG 10 20 30 160 170 180 190 200 210 pF1KSD PVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEER 40 50 60 70 80 90 220 230 240 250 260 270 pF1KSD QTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARS 100 110 120 130 140 150 280 290 300 310 320 330 pF1KSD LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPM 160 170 180 190 200 210 340 350 360 370 380 390 pF1KSD EVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLK 220 230 240 250 260 270 400 410 420 430 440 450 pF1KSD NAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSS 280 290 300 310 320 330 460 470 480 490 500 pF1KSD LFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 340 350 360 370 >>XP_005251746 (OMIM: 608745) PREDICTED: calcium-binding (366 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2251.8 bits: 425.7 E(85289): 1.1e-118 Smith-Waterman score: 2366; 96.6% identity (96.6% similar) in 378 aa overlap (124-501:1-366) 100 110 120 130 140 150 pF1KSD HYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWG ::::::::::::::::::::: XP_005 MQSLRDLGVKISEQQAEKILKS-------- 10 20 160 170 180 190 200 210 pF1KSD PVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ----MDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEER 30 40 50 60 70 220 230 240 250 260 270 pF1KSD QTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARS 80 90 100 110 120 130 280 290 300 310 320 330 pF1KSD LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPM 140 150 160 170 180 190 340 350 360 370 380 390 pF1KSD EVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLK 200 210 220 230 240 250 400 410 420 430 440 450 pF1KSD NAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSS 260 270 280 290 300 310 460 470 480 490 500 pF1KSD LFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 320 330 340 350 360 >>NP_443133 (OMIM: 608745) calcium-binding mitochondrial (469 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2250.6 bits: 425.9 E(85289): 1.3e-118 Smith-Waterman score: 2705; 96.3% identity (96.8% similar) in 432 aa overlap (70-501:50-469) 40 50 60 70 80 90 pF1KSD QMASFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDH :. .:::::::::::::::::::::::::: NP_443 YFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDH 20 30 40 50 60 70 100 110 120 130 140 150 pF1KSD EKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMD ::::::::::::::::::::::::::::::::::::::::::::: :: NP_443 EKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS------------MD 80 90 100 110 120 160 170 180 190 200 210 pF1KSD KNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 KNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWW 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 370 380 390 400 410 420 460 470 480 490 500 pF1KSD RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR :::::::::::::::::::::::::::::::::::::::::: NP_443 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 430 440 450 460 >>NP_001006643 (OMIM: 608745) calcium-binding mitochondr (489 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2250.4 bits: 425.9 E(85289): 1.3e-118 Smith-Waterman score: 3213; 97.4% identity (97.4% similar) in 501 aa overlap (1-501:1-489) 10 20 30 40 50 60 pF1KSD MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFLGKQDGRAEATEKRPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFLGKQDGRAEATEKRPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPV :::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 QEIMQSLRDLGVKISEQQAEKILKS------------MDKNGTMTIDWNEWRDYHLLHPV 130 140 150 160 190 200 210 220 230 240 pF1KSD ENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KSD RLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KSD RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILA 290 300 310 320 330 340 370 380 390 400 410 420 pF1KSD REGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSS 350 360 370 380 390 400 430 440 450 460 470 480 pF1KSD TCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIP 410 420 430 440 450 460 490 500 pF1KSD AVSISYVVYENLKITLGVQSR ::::::::::::::::::::: NP_001 AVSISYVVYENLKITLGVQSR 470 480 >>NP_001006642 (OMIM: 608745) calcium-binding mitochondr (503 aa) initn: 2275 init1: 2275 opt: 2275 Z-score: 2250.3 bits: 425.9 E(85289): 1.3e-118 Smith-Waterman score: 2698; 96.7% identity (97.0% similar) in 429 aa overlap (73-501:87-503) 50 60 70 80 90 100 pF1KSD SFLGKQDGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKK .::::::::::::::::::::::::::::: NP_001 LDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQDHEKK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD LRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNG :::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 LRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKS------------MDKNG 120 130 140 150 160 170 180 190 200 210 220 pF1KSD TMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHL 170 180 190 200 210 220 230 240 250 260 270 280 pF1KSD VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINV 230 240 250 260 270 280 290 300 310 320 330 340 pF1KSD LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL 290 300 310 320 330 340 350 360 370 380 390 400 pF1KSD RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 350 360 370 380 390 400 410 420 430 440 450 460 pF1KSD NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 410 420 430 440 450 460 470 480 490 500 pF1KSD GAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR ::::::::::::::::::::::::::::::::::::::: NP_001 GAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 470 480 490 500 >>NP_077008 (OMIM: 608746) calcium-binding mitochondrial (468 aa) initn: 1829 init1: 1758 opt: 1758 Z-score: 1741.6 bits: 331.7 E(85289): 2.9e-90 Smith-Waterman score: 2017; 64.2% identity (84.0% similar) in 480 aa overlap (29-501:1-468) 10 20 30 40 50 pF1KSD MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFL-----GKQDGRAEAT .::.:. : : : . : ...:::... NP_077 MRGSPGDAERRQRWGRLFEELDSNKDGRVDVH 10 20 30 60 70 80 90 100 110 pF1KSD EKRPTILLVVG--PAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKK : : . . : : . : . :: : :: ::.::: .:::..:..: :.:.:::.. NP_077 ELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRN 40 50 60 70 80 90 120 130 140 150 160 170 pF1KSD NDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRD .::.::..::.::.: ::..:: .::::::. ::..:::::::.:::: NP_077 QDGHIDVSEIQQSFRALGISISLEQAEKILHS------------MDRDGTMTIDWQEWRD 100 110 120 130 140 180 190 200 210 220 230 pF1KSD YHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSR . ::: .::. ... .:::::..:.:: :::::::. .:. :::::..::::. :::::: NP_077 HFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSR 150 160 170 180 190 200 240 250 260 270 280 290 pF1KSD TCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKF : :::::::::.::::::..: ..:.::. .:. ::: :::::::::::::::::::::: NP_077 TGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKF 210 220 230 240 250 260 300 310 320 330 340 350 pF1KSD MAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLD :::::::: . ..::::...::.:::::::: ::. ::::::::::..::.::::.:.:: NP_077 MAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLD 270 280 290 300 310 320 360 370 380 390 400 410 pF1KSD CARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLL :::::: ::: :::.::.::.::::::::::::::::::: :::.:. .:::::..::: NP_077 CARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLL 330 340 350 360 370 380 420 430 440 450 460 470 pF1KSD ACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAP ::::.::::::.::::::::::::::::::::.:...: .:..::: :: :::::.:: NP_077 ACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAP 390 400 410 420 430 440 480 490 500 pF1KSD NFMKVIPAVSISYVVYENLKITLGVQSR ::::::::::::::::::.: .::: :: NP_077 NFMKVIPAVSISYVVYENMKQALGVTSR 450 460 >>XP_011526577 (OMIM: 608746) PREDICTED: calcium-binding (577 aa) initn: 1829 init1: 1758 opt: 1758 Z-score: 1740.6 bits: 331.8 E(85289): 3.3e-90 Smith-Waterman score: 2017; 64.2% identity (84.0% similar) in 480 aa overlap (29-501:1-468) 10 20 30 40 50 pF1KSD MLQMLWHFLASFFPRAGCHGSREGDDREVRGTPAPAWRDQMASFL-----GKQDGRAEAT .::.:. : : : . : ...:::... XP_011 MRGSPGDAERRQRWGRLFEELDSNKDGRVDVH 10 20 30 60 70 80 90 100 110 pF1KSD EKRPTILLVVG--PAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKK : : . . : : . : . :: : :: ::.::: .:::..:..: :.:.:::.. XP_011 ELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRN 40 50 60 70 80 90 120 130 140 150 160 170 pF1KSD NDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRD .::.::..::.::.: ::..:: .::::::. ::..:::::::.:::: XP_011 QDGHIDVSEIQQSFRALGISISLEQAEKILHS------------MDRDGTMTIDWQEWRD 100 110 120 130 140 180 190 200 210 220 230 pF1KSD YHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSR . ::: .::. ... .:::::..:.:: :::::::. .:. :::::..::::. :::::: XP_011 HFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSR 150 160 170 180 190 200 240 250 260 270 280 290 pF1KSD TCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKF : :::::::::.::::::..: ..:.::. .:. ::: :::::::::::::::::::::: XP_011 TGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKF 210 220 230 240 250 260 300 310 320 330 340 350 pF1KSD MAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLD :::::::: . ..::::...::.:::::::: ::. ::::::::::..::.::::.:.:: XP_011 MAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLD 270 280 290 300 310 320 360 370 380 390 400 410 pF1KSD CARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLL :::::: ::: :::.::.::.::::::::::::::::::: :::.:. .:::::..::: XP_011 CARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLL 330 340 350 360 370 380 420 430 440 450 460 470 pF1KSD ACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAP ::::.::::::.::::::::::::::::::::.:...: .:..::: :: :::::.:: XP_011 ACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAP 390 400 410 420 430 440 480 490 500 pF1KSD NFMKVIPAVSISYVVYENLKITLGVQSR ::::::::::::::::::.: .::: :: XP_011 NFMKVIPAVSISYVVYENMKQALGVTSRLEYSGSISDHCNLCLPGSSDSPASASRVAGIT 450 460 470 480 490 500 501 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:39:13 2016 done: Thu Nov 3 07:39:15 2016 Total Scan time: 9.320 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]