FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1911, 840 aa 1>>>pF1KSDA1911 840 - 840 aa - 840 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0239+/-0.000549; mu= -2.6151+/- 0.034 mean_var=220.8169+/-45.227, 0's: 0 Z-trim(114.2): 66 B-trim: 261 in 2/50 Lambda= 0.086309 statistics sampled from 23950 (23989) to 23950 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.281), width: 16 Scan time: 13.550 The best scores are: opt bits E(85289) XP_011524100 (OMIM: 609674) PREDICTED: N-acetyltra ( 840) 5460 693.9 7.9e-199 NP_443143 (OMIM: 609674) N-acetyltransferase ESCO1 ( 840) 5460 693.9 7.9e-199 XP_011524101 (OMIM: 609674) PREDICTED: N-acetyltra ( 810) 4166 532.7 2.5e-150 NP_001017420 (OMIM: 268300,269000,609353) N-acetyl ( 601) 1055 145.3 7.8e-34 XP_011542723 (OMIM: 268300,269000,609353) PREDICTE ( 601) 1055 145.3 7.8e-34 XP_011542724 (OMIM: 268300,269000,609353) PREDICTE ( 591) 951 132.4 6.1e-30 >>XP_011524100 (OMIM: 609674) PREDICTED: N-acetyltransfe (840 aa) initn: 5460 init1: 5460 opt: 5460 Z-score: 3690.5 bits: 693.9 E(85289): 7.9e-199 Smith-Waterman score: 5460; 99.9% identity (99.9% similar) in 840 aa overlap (1-840:1-840) 10 20 30 40 50 60 pF1KSD MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QCNRFFPSRKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_011 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST 790 800 810 820 830 840 >>NP_443143 (OMIM: 609674) N-acetyltransferase ESCO1 [Ho (840 aa) initn: 5460 init1: 5460 opt: 5460 Z-score: 3690.5 bits: 693.9 E(85289): 7.9e-199 Smith-Waterman score: 5460; 99.9% identity (99.9% similar) in 840 aa overlap (1-840:1-840) 10 20 30 40 50 60 pF1KSD MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QCNRFFPSRKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_443 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST 790 800 810 820 830 840 >>XP_011524101 (OMIM: 609674) PREDICTED: N-acetyltransfe (810 aa) initn: 5239 init1: 4166 opt: 4166 Z-score: 2820.0 bits: 532.7 E(85289): 2.5e-150 Smith-Waterman score: 5183; 96.3% identity (96.3% similar) in 840 aa overlap (1-840:1-810) 10 20 30 40 50 60 pF1KSD MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QCNRFFPSRKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_011 QCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILA ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYV--------- 610 620 630 640 650 670 680 690 700 710 720 pF1KSD EYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG ::::::::::::::::::::::::::::::::::::::: XP_011 ---------------------VDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVG 660 670 680 690 730 740 750 760 770 780 pF1KSD CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRR 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST 760 770 780 790 800 810 >>NP_001017420 (OMIM: 268300,269000,609353) N-acetyltran (601 aa) initn: 1000 init1: 602 opt: 1055 Z-score: 728.5 bits: 145.3 E(85289): 7.8e-34 Smith-Waterman score: 1068; 37.7% identity (66.9% similar) in 522 aa overlap (322-833:104-599) 300 310 320 330 340 350 pF1KSD LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL ...:. ... :.: : :. .. . . NP_001 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV 80 90 100 110 120 130 360 370 380 390 400 pF1KSD HQKETNQDVQCN---RFFPS-RKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKL .:..:. : . .. :. :. :::. :. :: :.: : . : :. :. NP_001 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE 140 150 160 170 180 410 420 430 440 450 460 pF1KSD DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV ... .:.. : ...: . . . :. : :. . ..: . .. .:: . NP_001 NNSNAPRV--LSQKIKPQVTLQG---GAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI 190 200 210 220 230 240 470 480 490 500 510 520 pF1KSD KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- . .:. : . :. .:.. :. :....: .. :::.:: . .... .. NP_001 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR 250 260 270 280 290 530 540 550 560 570 580 pF1KSD -SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCN : :. . . .: .. . :::: . . :.: .: .: .. :. . : NP_001 VSSKEHKVDKNEAFS-SEDSLGENKTISPKSTVYPIFSA-SSVNSKRSLGEEQFSVGSVN 300 310 320 330 340 350 590 600 610 620 630 640 pF1KSD SHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFH . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. : NP_001 FMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHH 360 370 380 390 400 410 650 660 670 680 690 700 pF1KSD NQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLM ..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::. NP_001 HRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPK 420 430 440 450 460 470 710 720 730 740 750 760 pF1KSD CYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTL : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: :: . NP_001 CPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQCSDV 480 490 500 510 520 770 780 790 800 810 820 pF1KSD PEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQ ::::.::::::::: . :::.:: :... ::. :..: .:: .::::::::::::::::. NP_001 PEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATK 530 540 550 560 570 580 830 840 pF1KSD YCGTGQFLVYNFINGQNST ::.: .:::::: NP_001 YCNTPNFLVYNFNS 590 600 >>XP_011542723 (OMIM: 268300,269000,609353) PREDICTED: N (601 aa) initn: 1000 init1: 602 opt: 1055 Z-score: 728.5 bits: 145.3 E(85289): 7.8e-34 Smith-Waterman score: 1068; 37.7% identity (66.9% similar) in 522 aa overlap (322-833:104-599) 300 310 320 330 340 350 pF1KSD LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL ...:. ... :.: : :. .. . . XP_011 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV 80 90 100 110 120 130 360 370 380 390 400 pF1KSD HQKETNQDVQCN---RFFPS-RKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKL .:..:. : . .. :. :. :::. :. :: :.: : . : :. :. XP_011 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE 140 150 160 170 180 410 420 430 440 450 460 pF1KSD DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV ... .:.. : ...: . . . :. : :. . ..: . .. .:: . XP_011 NNSNAPRV--LSQKIKPQVTLQG---GAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI 190 200 210 220 230 240 470 480 490 500 510 520 pF1KSD KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- . .:. : . :. .:.. :. :....: .. :::.:: . .... .. XP_011 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR 250 260 270 280 290 530 540 550 560 570 580 pF1KSD -SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCN : :. . . .: .. . :::: . . :.: .: .: .. :. . : XP_011 VSSKEHKVDKNEAFS-SEDSLGENKTISPKSTVYPIFSA-SSVNSKRSLGEEQFSVGSVN 300 310 320 330 340 350 590 600 610 620 630 640 pF1KSD SHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFH . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. : XP_011 FMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHH 360 370 380 390 400 410 650 660 670 680 690 700 pF1KSD NQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLM ..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::. XP_011 HRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPK 420 430 440 450 460 470 710 720 730 740 750 760 pF1KSD CYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTL : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: :: . XP_011 CPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQCSDV 480 490 500 510 520 770 780 790 800 810 820 pF1KSD PEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQ ::::.::::::::: . :::.:: :... ::. :..: .:: .::::::::::::::::. XP_011 PEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATK 530 540 550 560 570 580 830 840 pF1KSD YCGTGQFLVYNFINGQNST ::.: .:::::: XP_011 YCNTPNFLVYNFNS 590 600 >>XP_011542724 (OMIM: 268300,269000,609353) PREDICTED: N (591 aa) initn: 896 init1: 602 opt: 951 Z-score: 658.6 bits: 132.4 E(85289): 6.1e-30 Smith-Waterman score: 964; 36.2% identity (65.6% similar) in 503 aa overlap (322-814:104-580) 300 310 320 330 340 350 pF1KSD LEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQIL ...:. ... :.: : :. .. . . XP_011 GSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEK--MQGKPV 80 90 100 110 120 130 360 370 380 390 400 pF1KSD HQKETNQDVQCN---RFFPS-RKTKPVKCILNGINSLAKKNSNWTKIKLSKFNSVQHNKL .:..:. : . .. :. :. :::. :. :: :.: : . : :. :. XP_011 CSKKNNKKPQKSLTAKYQPKYRHIKPVS--RNSRNS--KQNRVIYKPIVEKENNC-HSAE 140 150 160 170 180 410 420 430 440 450 460 pF1KSD DSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQE----KMKEINSEEV ... .:. .: ...: .. . :. : :. . ..: . .. .:: . XP_011 NNSNAPR--VLSQKIKP---QVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVI 190 200 210 220 230 240 470 480 490 500 510 520 pF1KSD KINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLEN- . .:. : . :. .:.. :. :....: .. :::.:: . .... .. XP_011 EDSDV--------ETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDR 250 260 270 280 290 530 540 550 560 570 580 pF1KSD -SPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCN : :. . . .:. . :::: . . :.: .: .: .. :. . : XP_011 VSSKEHKVDKNEAFSSED-SLGENKTISPKSTVYPIFSA-SSVNSKRSLGEEQFSVGSVN 300 310 320 330 340 350 590 600 610 620 630 640 pF1KSD SHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFH . .: :. . ... : . :::::::::.:::. :. :::.::::::::: ::. : XP_011 FMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHH 360 370 380 390 400 410 650 660 670 680 690 700 pF1KSD NQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLM ..:. ..:::::::::..::. ::.:..:::.::..:.:::....:.:::.:::::. XP_011 HRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPK 420 430 440 450 460 470 710 720 730 740 750 760 pF1KSD CYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTL : .. ::.::::..:.:::::::: :. ..::. : :. . : : .:: :: . XP_011 CPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSE--PI--GPESPSSTECPRAWQCSDV 480 490 500 510 520 770 780 790 800 810 820 pF1KSD PEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQ ::::.::::::::: . :::.:: :... ::. :..: .:: .:::::::::: XP_011 PEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDDCRRLNR 530 540 550 560 570 580 830 840 pF1KSD YCGTGQFLVYNFINGQNST XP_011 YQET 590 840 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:42:32 2016 done: Thu Nov 3 07:42:34 2016 Total Scan time: 13.550 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]