FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1934, 448 aa 1>>>pF1KSDA1934 448 - 448 aa - 448 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9848+/-0.000316; mu= 15.8394+/- 0.020 mean_var=104.5270+/-20.545, 0's: 0 Z-trim(118.5): 33 B-trim: 1746 in 1/54 Lambda= 0.125447 statistics sampled from 31393 (31428) to 31393 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.368), width: 16 Scan time: 9.860 The best scores are: opt bits E(85289) NP_001096621 (OMIM: 300916) paraneoplastic antigen ( 448) 2996 552.6 7.5e-157 NP_443158 (OMIM: 300916) paraneoplastic antigen-li ( 448) 2996 552.6 7.5e-157 NP_001171853 (OMIM: 300916) paraneoplastic antigen ( 448) 2996 552.6 7.5e-157 XP_016884741 (OMIM: 300916) PREDICTED: paraneoplas ( 448) 2996 552.6 7.5e-157 NP_001096620 (OMIM: 300916) paraneoplastic antigen ( 448) 2996 552.6 7.5e-157 XP_016884742 (OMIM: 300916) PREDICTED: paraneoplas ( 448) 2996 552.6 7.5e-157 NP_001269464 (OMIM: 300675) paraneoplastic antigen ( 455) 1135 215.8 1.9e-55 NP_037496 (OMIM: 300675) paraneoplastic antigen Ma ( 463) 1135 215.8 1.9e-55 NP_006020 (OMIM: 604010) paraneoplastic antigen Ma ( 353) 1072 204.3 4.2e-52 XP_011542667 (OMIM: 603970) PREDICTED: paraneoplas ( 364) 1047 199.8 9.8e-51 NP_009188 (OMIM: 603970) paraneoplastic antigen Ma ( 364) 1047 199.8 9.8e-51 NP_071434 (OMIM: 609485) modulator of apoptosis 1 ( 351) 1033 197.3 5.5e-50 NP_116271 (OMIM: 300917) paraneoplastic antigen-li ( 399) 923 177.4 6e-44 NP_776159 (OMIM: 300701) zinc finger CCHC domain-c ( 402) 489 98.9 2.7e-20 NP_001299820 (OMIM: 300701) zinc finger CCHC domai ( 402) 489 98.9 2.7e-20 >>NP_001096621 (OMIM: 300916) paraneoplastic antigen-lik (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: NP_001 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>NP_443158 (OMIM: 300916) paraneoplastic antigen-like p (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_443 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: NP_443 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>NP_001171853 (OMIM: 300916) paraneoplastic antigen-lik (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: NP_001 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>XP_016884741 (OMIM: 300916) PREDICTED: paraneoplastic (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: XP_016 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>NP_001096620 (OMIM: 300916) paraneoplastic antigen-lik (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: NP_001 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>XP_016884742 (OMIM: 300916) PREDICTED: paraneoplastic (448 aa) initn: 2996 init1: 2996 opt: 2996 Z-score: 2937.0 bits: 552.6 E(85289): 7.5e-157 Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARALGCCSLPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFEDWLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPG 370 380 390 400 410 420 430 440 pF1KSD REGPQAAGEELGNEAGAGAMSHPKPWET :::::::::::::::::::::::::::: XP_016 REGPQAAGEELGNEAGAGAMSHPKPWET 430 440 >>NP_001269464 (OMIM: 300675) paraneoplastic antigen Ma3 (455 aa) initn: 1126 init1: 611 opt: 1135 Z-score: 1116.6 bits: 215.8 E(85289): 1.9e-55 Smith-Waterman score: 1142; 45.3% identity (72.8% similar) in 408 aa overlap (1-403:1-395) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED : ::::.:::.: .. :. .::.::: .:.: :...:.. . . : :::.:::::::. NP_001 MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMFRREE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV ::.:...:::. ..:. :: .:::::: :::.::::: : :::.::: ::..: :...:. NP_001 NAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM 70 80 90 100 110 120 130 140 150 160 170 pF1KSD ARALGC---CSLPAESLDAE--VMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETF :.:: :: : ... : . :. . ..: :.: ::.:.::::.. :: .: NP_001 NRVLGSDTNCSAPRVTISPEFWTWAQTLGAAVQPLLEQMLYRELRVFSGNTISIPGALAF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD EDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIF . :::..::.. .::: : ::::::.: ::::::... :.:.: :::::.:: ::.:.: NP_001 DAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRASNASITVEECLAALQQVF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD GDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLAR : :. . .: .. .. . :::::.:.::::::::.::... .: :.... :::..:. NP_001 GPVESHKIAQVKLCKAYQEAGEKVSSFVLRLEPLLQRAVENNVVSRRNVNQTRLKRVLSG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD VAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQ ... :: ::.:. :: ::.:: :.::.:.::::: : . .. : .: .. : NP_001 ATLPDKLRDKLKLMKQRRKPPGFLALVKLLREEEEWEATL----GPDRESLEGLEVAPRP 310 320 330 340 350 360 370 380 390 400 410 pF1KSD ARAEASVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAE ..:.: ... :: :. :. :: .::: : . :: NP_001 PARITGVGAVPLPASGNSF-DARPS--QG-----YRRRRGRG-QHRRGGVARAGSRGSRK 360 370 380 390 400 420 430 440 pF1KSD NQTPGREGPQAAGEELGNEAGAGAMSHPKPWET NP_001 RKRHTFCYSCGEDGHIRVQCINPSNLLLAKETKEILEGGEREAQTNSR 410 420 430 440 450 >>NP_037496 (OMIM: 300675) paraneoplastic antigen Ma3 is (463 aa) initn: 1157 init1: 611 opt: 1135 Z-score: 1116.5 bits: 215.8 E(85289): 1.9e-55 Smith-Waterman score: 1152; 43.1% identity (68.3% similar) in 464 aa overlap (1-444:1-459) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED : ::::.:::.: .. :. .::.::: .:.: :...:.. . . : :::.:::::::. NP_037 MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMFRREE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV ::.:...:::. ..:. :: .:::::: :::.::::: : :::.::: ::..: :...:. NP_037 NAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM 70 80 90 100 110 120 130 140 150 160 170 pF1KSD ARALGC---CSLPAESLDAE--VMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETF :.:: :: : ... : . :. . ..: :.: ::.:.::::.. :: .: NP_037 NRVLGSDTNCSAPRVTISPEFWTWAQTLGAAVQPLLEQMLYRELRVFSGNTISIPGALAF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD EDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIF . :::..::.. .::: : ::::::.: ::::::... :.:.: :::::.:: ::.:.: NP_037 DAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRASNASITVEECLAALQQVF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD GDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLAR : :. . .: .. .. . :::::.:.::::::::.::... .: :.... :::..:. NP_037 GPVESHKIAQVKLCKAYQEAGEKVSSFVLRLEPLLQRAVENNVVSRRNVNQTRLKRVLSG 250 260 270 280 290 300 300 310 320 330 340 pF1KSD VAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENT-----EAV--MKNKEKPSGR- ... :: ::.:. :: ::.:: :.::.:.::::: : :.. .. .: .: NP_037 ATLPDKLRDKLKLMKQRRKPPGFLALVKLLREEEEWEATLGPDRESLEGLEVAPRPPARI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD -GRGASGRQARAEASVSAPQATVQARSFSDSSPQTIQGGLPPL-----VKRRRLLGSEST : :: : ... . :. . : . : .::. ::.: : NP_037 TGVGAVPLPASGNSFDARPSQGYRRRR---GRGQHRRGGVARAGSRGSRKRKRHTFCYSC 370 380 390 400 410 410 420 430 440 pF1KSD RGED-HGQATYPKAENQTPGREGPQAAGEELGNEAGAGAMSHPKPWET ::: : .. . : .. ::: : :: : :::: NP_037 -GEDGHIRVQCINPSNLLLVKQKKQAAVES-GNGNWAWDKSHPKSKAK 420 430 440 450 460 >>NP_006020 (OMIM: 604010) paraneoplastic antigen Ma1 [H (353 aa) initn: 889 init1: 557 opt: 1072 Z-score: 1056.5 bits: 204.3 E(85289): 4.2e-52 Smith-Waterman score: 1072; 46.9% identity (78.5% similar) in 339 aa overlap (1-335:1-338) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED ::.:::::::.:::.. ..:::. :::..:.:.::..:..:.. : .::.::::: ::. NP_006 MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAM-PQVSYRMLGRMFWREE 10 20 30 40 50 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV ::::...::. .:.:...: ..::::: :.:. :: . : ::: ::. :: :: .. :: NP_006 NAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDV 60 70 80 90 100 110 130 140 150 160 170 pF1KSD ARALGCCS---LPAESLDAEVMPQVRSPPLEPPKESMWYRKLKVFSGTASPSPGEETFED ::.:: . :. . ::.. . . ..: ::.::..: .::: :.::::::. NP_006 ARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEETFDP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD WLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGD :::...:.. ::::.:::::::.::::::: ...:.:..:: .::. .:: ::.:.::. NP_006 WLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD KEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVA :. : .:..::.: . :::.:....::::::::.:.:. .. .... ::....: . NP_006 VESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGAN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD MTPALRGKLELLDQ-RGCPPNFLELMKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQA . :.: .: : .: ::...:. ::.:: :. : NP_006 HSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KSD RAEASVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHGQATYPKAEN >>XP_011542667 (OMIM: 603970) PREDICTED: paraneoplastic (364 aa) initn: 1038 init1: 624 opt: 1047 Z-score: 1031.8 bits: 199.8 E(85289): 9.8e-51 Smith-Waterman score: 1047; 46.7% identity (76.5% similar) in 362 aa overlap (1-349:1-357) 10 20 30 40 50 60 pF1KSD MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED :::.::::::. :..: .:.:...::: . :.:::.... :. : ::.::..::... XP_011 MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV ::.::..:: . .. ...::.. :::: :.:. : : : ::: ::: ::. ::.... . XP_011 NANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGM 70 80 90 100 110 120 130 140 150 160 170 pF1KSD ARALGC-----CSLPAES--LDAEVMPQV--RSP-PLEPPKESMWYRKLKVFSGTASPSP :::: ..: : : :... :. ..: :: : : ::::.::::.: :.: XP_011 FRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLP----MRYRKLRVFSGSAVPAP 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GEETFEDWLEQVTEIMPIWQVSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDA ::.:: ::::.:::. : :.:.::.: : ::::::::..:...::.: ::.::.::.: XP_011 EEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD LKQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLK .::.::. :. :..: :.:.: . :::::...:::: ::..::.: . : .:..::. XP_011 FKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLE 240 250 260 270 280 290 300 310 320 330 340 pF1KSD HLLARVAMTPALRGKLELLDQRGCPPNFLELMKLIRDEEEWENT---EAVMKNKEKPSGR ...: .... : .:. : ..: ::.::::::.::.::: : . :.. . .:. .: XP_011 QVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEER-DGY 300 310 320 330 340 350 350 360 370 380 390 400 pF1KSD GRGASGRQARAEASVSAPQATVQARSFSDSSPQTIQGGLPPLVKRRRLLGSESTRGEDHG :: XP_011 GRWNHEGDD 360 448 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:13:09 2016 done: Thu Nov 3 19:13:10 2016 Total Scan time: 9.860 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]