FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1942, 446 aa 1>>>pF1KSDA1942 446 - 446 aa - 446 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0422+/-0.000342; mu= 10.6963+/- 0.022 mean_var=190.3938+/-41.507, 0's: 0 Z-trim(119.7): 215 B-trim: 107 in 1/52 Lambda= 0.092950 statistics sampled from 33732 (34019) to 33732 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.399), width: 16 Scan time: 10.500 The best scores are: opt bits E(85289) NP_113673 (OMIM: 610597) glutamate-rich WD repeat- ( 446) 3068 424.0 4e-118 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 296 52.0 2.3e-06 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 296 52.1 2.5e-06 XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982) 272 49.4 4.9e-05 XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 272 49.5 5.7e-05 NP_851782 (OMIM: 609005) WD repeat-containing prot (1283) 272 49.6 5.9e-05 XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290) 272 49.6 5.9e-05 XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 272 49.6 5.9e-05 XP_016863179 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 272 49.6 5.9e-05 XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 272 49.6 5.9e-05 XP_016863176 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 272 49.6 5.9e-05 XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 272 49.6 5.9e-05 NP_733828 (OMIM: 609005) WD repeat-containing prot (1322) 272 49.6 6e-05 NP_001128728 (OMIM: 602923) histone-binding protei ( 390) 240 44.7 0.00053 NP_001128727 (OMIM: 602923) histone-binding protei ( 424) 240 44.7 0.00056 NP_005601 (OMIM: 602923) histone-binding protein R ( 425) 240 44.7 0.00056 XP_016866423 (OMIM: 215100,266500,601757,614879) P ( 199) 223 42.1 0.0016 NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 220 42.0 0.0036 NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 220 42.1 0.0038 XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 217 41.5 0.004 NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 217 41.5 0.004 NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 217 41.5 0.004 NP_001129669 (OMIM: 603619) fizzy-related protein ( 404) 218 41.7 0.0042 NP_057347 (OMIM: 603619) fizzy-related protein hom ( 493) 218 41.8 0.0047 NP_001129670 (OMIM: 603619) fizzy-related protein ( 496) 218 41.9 0.0048 XP_005259630 (OMIM: 603619) PREDICTED: fizzy-relat ( 496) 218 41.9 0.0048 XP_016877356 (OMIM: 604447) PREDICTED: guanine nuc ( 212) 212 40.6 0.0048 XP_016882352 (OMIM: 603619) PREDICTED: fizzy-relat ( 528) 218 41.9 0.005 XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 220 42.4 0.0057 NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 220 42.4 0.0059 XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 212 40.8 0.006 NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 212 40.9 0.0066 XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 212 40.9 0.0066 NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 212 40.9 0.0072 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 210 40.7 0.0092 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 210 40.8 0.0098 >>NP_113673 (OMIM: 610597) glutamate-rich WD repeat-cont (446 aa) initn: 3068 init1: 3068 opt: 3068 Z-score: 2241.7 bits: 424.0 E(85289): 4e-118 Smith-Waterman score: 3068; 99.8% identity (100.0% similar) in 446 aa overlap (1-446:1-446) 10 20 30 40 50 60 pF1KSD MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LTTATAHDGDVNVISWSRQEPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_113 LTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL 370 380 390 400 410 420 430 440 pF1KSD HWHPQCPGLLVSTALSGFTIFRTISV :::::::::::::::::::::::::: NP_113 HWHPQCPGLLVSTALSGFTIFRTISV 430 440 >>XP_005267076 (OMIM: 215100,266500,601757,614879) PREDI (285 aa) initn: 217 init1: 120 opt: 296 Z-score: 235.1 bits: 52.0 E(85289): 2.3e-06 Smith-Waterman score: 301; 26.8% identity (55.3% similar) in 228 aa overlap (197-422:56-269) 170 180 190 200 210 220 pF1KSD GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSP-R : : :. . : : ...::: : XP_005 FDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTR 30 40 50 60 70 80 230 240 250 260 270 280 pF1KSD VTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADAS ...:. .....:: :: : : . : :: . . ::: ::: :.: . XP_005 GEQLVVSGSWDQTVKLWDPTVGKSLCT----FRGHESIIYSTIWSPHIPGCFASASGDQT 90 100 110 120 130 140 290 300 310 320 330 340 pF1KSD IRIWDIRAAPSKACMLTTATAHDGDVNVISWSR-QEPFLLSGGDDGALKIWDLRQFKSGS .::::..:: . . ::.... .: . .: .:..:. : .:. ::::. .. XP_005 LRIWDVKAAGVRIVI----PAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQ-- 150 160 170 180 190 350 360 370 380 390 400 pF1KSD PVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLP :: . :. . :.. : ..:.:. . : . :... :.. .:. ... XP_005 PVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFS---KPDSL-LETVEHHTEFT 200 210 220 230 240 250 410 420 430 440 pF1KSD QQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV : : :. :.. . : XP_005 CGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA 260 270 280 >>NP_000279 (OMIM: 215100,266500,601757,614879) peroxiso (323 aa) initn: 241 init1: 120 opt: 296 Z-score: 234.4 bits: 52.1 E(85289): 2.5e-06 Smith-Waterman score: 301; 26.8% identity (55.3% similar) in 228 aa overlap (197-422:94-307) 170 180 190 200 210 220 pF1KSD GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSP-R : : :. . : : ...::: : NP_000 FDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTR 70 80 90 100 110 120 230 240 250 260 270 280 pF1KSD VTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADAS ...:. .....:: :: : : . : :: . . ::: ::: :.: . NP_000 GEQLVVSGSWDQTVKLWDPTVGKSLCT----FRGHESIIYSTIWSPHIPGCFASASGDQT 130 140 150 160 170 290 300 310 320 330 340 pF1KSD IRIWDIRAAPSKACMLTTATAHDGDVNVISWSR-QEPFLLSGGDDGALKIWDLRQFKSGS .::::..:: . . ::.... .: . .: .:..:. : .:. ::::. .. NP_000 LRIWDVKAAGVRIVI----PAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQ-- 180 190 200 210 220 230 350 360 370 380 390 400 pF1KSD PVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLP :: . :. . :.. : ..:.:. . : . :... :.. .:. ... NP_000 PVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFS---KPDSL-LETVEHHTEFT 240 250 260 270 280 410 420 430 440 pF1KSD QQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV : : :. :.. . : NP_000 CGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA 290 300 310 320 >>XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-conta (982 aa) initn: 226 init1: 116 opt: 272 Z-score: 211.4 bits: 49.4 E(85289): 4.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:520-696) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_016 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 490 500 510 520 530 540 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_016 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 550 560 570 580 590 600 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_016 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 610 620 630 640 650 660 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_016 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 670 680 690 700 710 720 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_016 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 730 740 750 760 770 780 >>XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-conta (1216 aa) initn: 226 init1: 116 opt: 272 Z-score: 210.3 bits: 49.5 E(85289): 5.7e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:422-598) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_005 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 400 410 420 430 440 450 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_005 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 460 470 480 490 500 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_005 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 510 520 530 540 550 560 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_005 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 570 580 590 600 610 620 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_005 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 630 640 650 660 670 680 >>NP_851782 (OMIM: 609005) WD repeat-containing protein (1283 aa) initn: 226 init1: 116 opt: 272 Z-score: 210.0 bits: 49.6 E(85289): 5.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:496-672) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... NP_851 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 470 480 490 500 510 520 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . NP_851 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 530 540 550 560 570 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. NP_851 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 580 590 600 610 620 630 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: NP_851 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 640 650 660 670 680 690 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV NP_851 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 700 710 720 730 740 750 >>XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-conta (1290 aa) initn: 226 init1: 116 opt: 272 Z-score: 210.0 bits: 49.6 E(85289): 5.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:496-672) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_011 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 470 480 490 500 510 520 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_011 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 530 540 550 560 570 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_011 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 580 590 600 610 620 630 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_011 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 640 650 660 670 680 690 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_011 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 700 710 720 730 740 750 >>XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-conta (1307 aa) initn: 226 init1: 116 opt: 272 Z-score: 209.9 bits: 49.6 E(85289): 5.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:520-696) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_016 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 490 500 510 520 530 540 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_016 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 550 560 570 580 590 600 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_016 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 610 620 630 640 650 660 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_016 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 670 680 690 700 710 720 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_016 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 730 740 750 760 770 780 >>XP_016863179 (OMIM: 609005) PREDICTED: WD repeat-conta (1307 aa) initn: 226 init1: 116 opt: 272 Z-score: 209.9 bits: 49.6 E(85289): 5.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:520-696) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_016 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 490 500 510 520 530 540 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_016 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 550 560 570 580 590 600 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_016 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 610 620 630 640 650 660 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_016 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 670 680 690 700 710 720 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_016 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 730 740 750 760 770 780 >>XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-conta (1314 aa) initn: 226 init1: 116 opt: 272 Z-score: 209.9 bits: 49.6 E(85289): 5.9e-05 Smith-Waterman score: 272; 28.5% identity (57.5% similar) in 186 aa overlap (213-397:520-696) 190 200 210 220 230 240 pF1KSD LLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW : . :. ::: . :: . :.... XP_016 HKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY 490 500 510 520 530 540 250 260 270 280 290 300 pF1KSD TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLT . ... . . : ::: .: ..::: .. .. : : :...:::: . ::. . XP_016 YVATSSDQPL--KVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYT---QDACI-N 550 560 570 580 590 600 310 320 330 340 350 360 pF1KSD TATAHDGDVNVISWSRQEPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW ..: . : . :. . :.:: ::. : ..:.:: :. :. : : .: : : .. XP_016 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE---GTCVDTVYDHGADVYGLTC 610 620 630 640 650 660 370 380 390 400 410 420 pF1KSD HPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELH ::. ..:. . : . :.:.. : .. :: XP_016 HPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCG 670 680 690 700 710 720 430 440 pF1KSD WHPQCPGLLVSTALSGFTIFRTISV XP_016 KVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKG 730 740 750 760 770 780 446 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:45:41 2016 done: Thu Nov 3 07:45:42 2016 Total Scan time: 10.500 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]