FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1950, 498 aa 1>>>pF1KSDA1950 498 - 498 aa - 498 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0103+/-0.000718; mu= 16.0577+/- 0.043 mean_var=101.6974+/-20.364, 0's: 0 Z-trim(112.4): 10 B-trim: 0 in 0/53 Lambda= 0.127180 statistics sampled from 13176 (13184) to 13176 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.405), width: 16 Scan time: 3.790 The best scores are: opt bits E(32554) CCDS34589.1 AMZ1 gene_id:155185|Hs108|chr7 ( 498) 3447 642.7 2.7e-184 CCDS64582.1 AMZ1 gene_id:155185|Hs108|chr7 ( 297) 1373 262.0 6.5e-70 CCDS11674.1 AMZ2 gene_id:51321|Hs108|chr17 ( 360) 728 143.7 3.2e-34 CCDS32714.1 AMZ2 gene_id:51321|Hs108|chr17 ( 302) 475 97.2 2.6e-20 >>CCDS34589.1 AMZ1 gene_id:155185|Hs108|chr7 (498 aa) initn: 3447 init1: 3447 opt: 3447 Z-score: 3422.2 bits: 642.7 E(32554): 2.7e-184 Smith-Waterman score: 3447; 100.0% identity (100.0% similar) in 498 aa overlap (1-498:1-498) 10 20 30 40 50 60 pF1KSD MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSA 430 440 450 460 470 480 490 pF1KSD RKLARAESAPRPWDGEES :::::::::::::::::: CCDS34 RKLARAESAPRPWDGEES 490 >>CCDS64582.1 AMZ1 gene_id:155185|Hs108|chr7 (297 aa) initn: 1406 init1: 1361 opt: 1373 Z-score: 1368.7 bits: 262.0 E(32554): 6.5e-70 Smith-Waterman score: 1381; 73.3% identity (78.7% similar) in 315 aa overlap (1-307:1-297) 10 20 30 40 50 60 pF1KSD MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL 130 140 150 160 170 180 190 200 210 220 230 pF1KSD SDLYPHEAWSFTFSKFLPGH-EVGVCSFARFSGEFP-----KSGPSAPDLALVEAAADGP :::::::::::::::::::: .: ::.: ..: . : . ::: :: CCDS64 SDLYPHEAWSFTFSKFLPGHGHVPRALPPSGPGELPLAPLPHAGCAQPGRG--PAAAPGP 190 200 210 220 230 240 250 260 270 280 290 pF1KSD EAPLQDRGWALC--FSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRP . : ... : : :.: : : :: . :. . ::.:. CCDS64 LSHLPEEA-AACPGFQAHREVP-------ETLHLDSGGGGDVAQPGGGGAVSVGGH---- 240 250 260 270 280 300 310 320 330 340 350 pF1KSD LDLCPICLRKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGM : : :.: ::: CCDS64 ----PACQRRLGHVL 290 >>CCDS11674.1 AMZ2 gene_id:51321|Hs108|chr17 (360 aa) initn: 654 init1: 300 opt: 728 Z-score: 727.9 bits: 143.7 E(32554): 3.2e-34 Smith-Waterman score: 728; 36.9% identity (68.6% similar) in 309 aa overlap (15-321:9-314) 10 20 30 40 50 60 pF1KSD MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI ..:: ::.: . .: . : .. .:. .. ::..: :: . . CCDS11 MQIIRHSEQTLKTALISKNPVLVSQY-EKLNAGEQRLMNEAFQPASDLFGPITL 10 20 30 40 50 70 80 90 100 110 pF1KSD RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPI-DLSEEPVGSS-LLHQLCS .. ::. :.::::.::. : .. .. : .. ::.: : .:.. . : .. : . CCDS11 HSPSDWITSHPEAPQDFEQFFSDPYRKTPSPNKRSIYIQSIGSLGNTRIISEEYIKWLTG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD CTEAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGL .:.: ::::: : : .. ::: : .... ::.:. ::.:::..:: ::.::.:. CCDS11 YCKAYFYGLRVKLLEPVPVSVTRCSFRVNENTHNLQIHAGDILKFLKKKKPEDAFCVVGI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD TLSDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPL :. ::::...:.:.:.. ::. ::::....: . .. : ..... . . CCDS11 TMIDLYPRDSWNFVFGQASLTDGVGIFSFARYGSDFYSMHYKGKVKKLKKTSSS--DYSI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD QDRGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPI : . .... ... ::. ::. :..:: .:.:: :::::. :.:: ::::.:::: CCDS11 FDNYYIPEITSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CLRKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDS ::.::: ..:: ..:::. : : CCDS11 CLHKLQCAVGFSIVERYKALVRWIDDESSDTPGATPEHSHEDNGNLPKPVEAFKEWKEWI 300 310 320 330 340 350 >>CCDS32714.1 AMZ2 gene_id:51321|Hs108|chr17 (302 aa) initn: 651 init1: 296 opt: 475 Z-score: 478.1 bits: 97.2 E(32554): 2.6e-20 Smith-Waterman score: 521; 31.3% identity (58.0% similar) in 307 aa overlap (15-321:9-256) 10 20 30 40 50 60 pF1KSD MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI ..:: ::.: . .: . : .. .:. .. ::..: :: . . CCDS32 MQIIRHSEQTLKTALISKNPVLVSQY-EKLNAGEQRLMNEAFQPASDLFGPITL 10 20 30 40 50 70 80 90 100 110 120 pF1KSD RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT .. ::. :.::::.::. : .. .. : .. ::.: : :. CCDS32 HSPSDWITSHPEAPQDFEQFFSDPYRKTPSPNKRSIYIQSI-------GD---------- 60 70 80 90 130 140 150 160 170 180 pF1KSD EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL ::.:::..:: ::.::.:.:. CCDS32 ---------------------------------------ILKFLKKKKPEDAFCVVGITM 100 110 190 200 210 220 230 240 pF1KSD SDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQD ::::...:.:.:.. ::. ::::....: . .. : ..... . . : CCDS32 IDLYPRDSWNFVFGQASLTDGVGIFSFARYGSDFYSMHYKGKVKKLKKTSSS--DYSIFD 120 130 140 150 160 170 250 260 270 280 290 300 pF1KSD RGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICL . .... ... ::. ::. :..:: .:.:: :::::. :.:: ::::.:::::: CCDS32 NYYIPEITSVLLLRSCKTLTHEIGHIFGLRHCQWLACLMQGSNHLEEADRRPLNLCPICL 180 190 200 210 220 230 310 320 330 340 350 360 pF1KSD RKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEP .::: ..:: ..:::. : : CCDS32 HKLQCAVGFSIVERYKALVRWIDDESSDTPGATPEHSHEDNGNLPKPVEAFKEWKEWIIK 240 250 260 270 280 290 498 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:13:45 2016 done: Thu Nov 3 19:13:46 2016 Total Scan time: 3.790 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]