Result of FASTA (omim) for
pF1KSDA1957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1957, 421 aa
1>>>pF1KSDA1957 421 - 421 aa - 421 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5160+/-0.000324; mu= 3.5556+/- 0.020
mean_var=188.0784+/-38.664, 0's: 0 Z-trim(122.0): 19 B-trim: 586 in 1/54
Lambda= 0.093520
statistics sampled from 39366 (39386) to 39366 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.462), width: 16
Scan time: 11.150
The best scores are: opt bits E(85289)
NP_001129735 (OMIM: 610336) C2 calcium-dependent d ( 421) 2784 387.6 3.2e-107
XP_011525996 (OMIM: 610336) PREDICTED: C2 calcium- ( 446) 2613 364.5 3e-100
XP_016877659 (OMIM: 610344) PREDICTED: C2 calcium- ( 364) 504 79.9 1.1e-14
NP_001007596 (OMIM: 610344) C2 calcium-dependent d ( 364) 504 79.9 1.1e-14
NP_997205 (OMIM: 610343) C2 calcium-dependent doma ( 369) 498 79.1 2e-14
>>NP_001129735 (OMIM: 610336) C2 calcium-dependent domai (421 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2045.9 bits: 387.6 E(85289): 3.2e-107
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)
10 20 30 40 50 60
pF1KSD MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF
370 380 390 400 410 420
pF1KSD L
:
NP_001 L
>>XP_011525996 (OMIM: 610336) PREDICTED: C2 calcium-depe (446 aa)
initn: 2613 init1: 2613 opt: 2613 Z-score: 1920.9 bits: 364.5 E(85289): 3e-100
Smith-Waterman score: 2613; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KSD MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF
:::::::::::::::::::::::::::::::::
XP_011 TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKPAAIQFPPRGEQGLAATPGPGSARDAP
370 380 390 400 410 420
pF1KSD L
XP_011 SQGSGLALGDPSFPGSGGEWGQARVP
430 440
>>XP_016877659 (OMIM: 610344) PREDICTED: C2 calcium-depe (364 aa)
initn: 580 init1: 184 opt: 504 Z-score: 384.3 bits: 79.9 E(85289): 1.1e-14
Smith-Waterman score: 589; 35.9% identity (56.7% similar) in 404 aa overlap (26-418:10-362)
10 20 30 40 50 60
pF1KSD MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
: ::..: : : ...::::..::.: :::.::.
XP_016 MRLLEKLCSSAAGSSAPK-PAFAKVLTPNRIPEFCIPPRLPA--
10 20 30 40
70 80 90 100 110 120
pF1KSD AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
: : :. . .:: .: . :::: .:: . . . ::
XP_016 ----------PCTLESPIRAAA---------VPRRCAAESDLWPRAADEDA----GRTDW
50 60 70
130 140 150 160 170 180
pF1KSD LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
::..:.:.::: .:...:.::: : :::::::::::. .:.:
XP_016 --------DPRSQAALSLPHLPRVRTTYGFCALLESPHTRRKESLL---------LGGPP
80 90 100 110 120
190 200 210 220 230
pF1KSD AGRRRAAAKANGGDGGPREAGGALMSP---GRYFS---GGESDTGSSAESSPFGSPLLSR
: : :: .. :: ::: :.: .: : :: .. ..: ::
XP_016 APRPRA--HSCGGGGGPDAPLGTLCGPRGPGPATPAAPGGPRLPQDALAAGPRRCRLLRV
130 140 150 160 170
240 250 260 270 280 290
pF1KSD SVSLL-KGFAQDSQAKVSQLRH-SVGRHGSLS-ADDSTPDASPGSRRRLTRRAPPEPGPE
.:: ... . .....: : : . : . .: .:.: :. ::: ::
XP_016 PDGLLSRALRAGRSRRLARVRSVSSGNEDEERRAGSESPARAPSSSP-LSSRAP---LPE
180 190 200 210 220 230
300 310 320 330 340 350
pF1KSD SGQARGEHTVHVGPRG-SVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCL
.:.: :: .: : ..:: ::: : :::..:: ::.:. :.. : ..: :
XP_016 RLEAKG--TVALGRAGDALRLAAEYCPGTRRLRLRLLRAESLFGGAPGPRAVRCRLSLVL
240 250 260 270 280 290
360 370 380 390 400
pF1KSD VP-GKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGE
: : . : :..: ::. :..:: ::::. ::.::.:.:. ..: . : :::.
XP_016 RPPGTARWQCSAVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRDRGRLLGQ
300 310 320 330 340 350
410 420
pF1KSD KELPLTSLLPFL
:: : .::
XP_016 GELSLGALLLL
360
>>NP_001007596 (OMIM: 610344) C2 calcium-dependent domai (364 aa)
initn: 580 init1: 184 opt: 504 Z-score: 384.3 bits: 79.9 E(85289): 1.1e-14
Smith-Waterman score: 589; 35.9% identity (56.7% similar) in 404 aa overlap (26-418:10-362)
10 20 30 40 50 60
pF1KSD MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
: ::..: : : ...::::..::.: :::.::.
NP_001 MRLLEKLCSSAAGSSAPK-PAFAKVLTPNRIPEFCIPPRLPA--
10 20 30 40
70 80 90 100 110 120
pF1KSD AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
: : :. . .:: .: . :::: .:: . . . ::
NP_001 ----------PCTLESPIRAAA---------VPRRCAAESDLWPRAADEDA----GRTDW
50 60 70
130 140 150 160 170 180
pF1KSD LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
::..:.:.::: .:...:.::: : :::::::::::. .:.:
NP_001 --------DPRSQAALSLPHLPRVRTTYGFCALLESPHTRRKESLL---------LGGPP
80 90 100 110 120
190 200 210 220 230
pF1KSD AGRRRAAAKANGGDGGPREAGGALMSP---GRYFS---GGESDTGSSAESSPFGSPLLSR
: : :: .. :: ::: :.: .: : :: .. ..: ::
NP_001 APRPRA--HSCGGGGGPDAPLGTLCGPRGPGPATPAAPGGPRLPQDALAAGPRRCRLLRV
130 140 150 160 170
240 250 260 270 280 290
pF1KSD SVSLL-KGFAQDSQAKVSQLRH-SVGRHGSLS-ADDSTPDASPGSRRRLTRRAPPEPGPE
.:: ... . .....: : : . : . .: .:.: :. ::: ::
NP_001 PDGLLSRALRAGRSRRLARVRSVSSGNEDEERRAGSESPARAPSSSP-LSSRAP---LPE
180 190 200 210 220 230
300 310 320 330 340 350
pF1KSD SGQARGEHTVHVGPRG-SVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCL
.:.: :: .: : ..:: ::: : :::..:: ::.:. :.. : ..: :
NP_001 RLEAKG--TVALGRAGDALRLAAEYCPGTRRLRLRLLRAESLFGGAPGPRAVRCRLSLVL
240 250 260 270 280 290
360 370 380 390 400
pF1KSD VP-GKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGE
: : . : :..: ::. :..:: ::::. ::.::.:.:. ..: . : :::.
NP_001 RPPGTARWQCSAVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRDRGRLLGQ
300 310 320 330 340 350
410 420
pF1KSD KELPLTSLLPFL
:: : .::
NP_001 GELSLGALLLL
360
>>NP_997205 (OMIM: 610343) C2 calcium-dependent domain-c (369 aa)
initn: 576 init1: 193 opt: 498 Z-score: 379.9 bits: 79.1 E(85289): 2e-14
Smith-Waterman score: 544; 34.4% identity (52.0% similar) in 427 aa overlap (6-418:1-367)
10 20 30 40 50
pF1KSD MRKTNMWFLERLRGSGENGAARG----VGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKL
:: ::::: . : : : : :. .::::::.::.: :::.:
NP_997 MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRL
10 20 30 40 50
60 70 80 90 100 110
pF1KSD PSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIES
::: ::: .: .. : . . .
NP_997 --------------------------------MPRLA--LAALRNSWVEEAG--MDEGAG
60 70
120 130 140 150 160 170
pF1KSD AEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQV
:: ::..:.:.::: .:...:.::: : :::::::::::. .
NP_997 RTDW--------DPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLL---------L
80 90 100 110 120
180 190 200 210 220 230
pF1KSD GSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSR--
:.: : : :: .. :: ::: :.: : : . : . .. . : . : :
NP_997 GGPPAPRPRA--HTYGGGGGPDALLGTLRVP-R--APGPATPAAPGCPRPPQDALARRPR
130 140 150 160 170
240 250 260 270 280
pF1KSD SVSLLK---GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPE---P
. ::. :. . . . : . : : . .:. :. : : .:: :
NP_997 GCRLLRVPDGLLSRALRAGRSRRLTRVRSVSSGNEDKERRAGSQSPARAPSTSPPSSRVP
180 190 200 210 220 230
290 300 310 320 330 340
pF1KSD GPESGQARGEHTVHVGPRG-SVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVG
:: .:.: :: .: : ..:: ::: : .:::..:: ::. :...: ..
NP_997 FPERLEAEG--TVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLS
240 250 260 270 280 290
350 360 370 380 390 400
pF1KSD LCLVP-GKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTL
: : : : .: ::.: ::. :..:: ::::. ::.::.:.:. ..: . .: :
NP_997 LVLRPPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRL
300 310 320 330 340 350
410 420
pF1KSD LGEKELPLTSLLPFL
::. :: : .::
NP_997 LGQGELSLGALLLL
360
421 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:48:37 2016 done: Thu Nov 3 07:48:39 2016
Total Scan time: 11.150 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]