Result of FASTA (omim) for
pF1KSDA1993
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1993, 504 aa
1>>>pF1KSDA1993 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9934+/-0.000567; mu= 6.9570+/- 0.034
mean_var=510.0813+/-125.083, 0's: 0 Z-trim(115.0): 1364 B-trim: 1401 in 1/52
Lambda= 0.056788
statistics sampled from 23264 (25190) to 23264 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.295), width: 16
Scan time: 8.870
The best scores are: opt bits E(85289)
XP_011517001 (OMIM: 611692) PREDICTED: zinc finger ( 504) 3370 292.0 2.7e-78
XP_005252046 (OMIM: 611692) PREDICTED: zinc finger ( 514) 3370 292.0 2.8e-78
NP_001092740 (OMIM: 611692) zinc finger and BTB do ( 500) 3347 290.1 1e-77
NP_001138810 (OMIM: 611439) zinc finger and BTB do ( 634) 450 52.9 3.1e-06
NP_005444 (OMIM: 611439) zinc finger and BTB domai ( 634) 450 52.9 3.1e-06
NP_862827 (OMIM: 608992) B-cell CLL/lymphoma 6 mem ( 480) 422 50.4 1.4e-05
XP_005259628 (OMIM: 605878) PREDICTED: zinc finger ( 584) 414 49.9 2.3e-05
NP_056982 (OMIM: 605878) zinc finger and BTB domai ( 584) 414 49.9 2.3e-05
NP_001304919 (OMIM: 605878) zinc finger and BTB do ( 584) 414 49.9 2.3e-05
XP_005259627 (OMIM: 605878) PREDICTED: zinc finger ( 634) 414 50.0 2.4e-05
NP_443108 (OMIM: 610672) nucleus accumbens-associa ( 527) 393 48.1 7.3e-05
XP_005259778 (OMIM: 610672) PREDICTED: nucleus acc ( 527) 393 48.1 7.3e-05
NP_055612 (OMIM: 614064,614069) zinc finger and BT ( 697) 376 47.0 0.00022
XP_011516523 (OMIM: 615786) PREDICTED: nucleus acc ( 587) 354 45.0 0.00071
NP_653254 (OMIM: 615786) nucleus accumbens-associa ( 587) 354 45.0 0.00071
XP_005271715 (OMIM: 176797,612447) PREDICTED: zinc ( 485) 322 42.3 0.004
NP_006617 (OMIM: 605976) zinc finger and BTB domai ( 424) 314 41.5 0.0059
XP_011507901 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711422 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711421 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711416 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711420 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711417 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711412 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
XP_006711419 (OMIM: 607646) PREDICTED: zinc finger ( 539) 315 41.8 0.0062
NP_001243384 (OMIM: 607646) zinc finger and BTB do ( 539) 315 41.8 0.0062
XP_011507900 (OMIM: 607646) PREDICTED: zinc finger ( 573) 315 41.8 0.0064
NP_001239335 (OMIM: 607646) zinc finger and BTB do ( 573) 315 41.8 0.0064
XP_016856888 (OMIM: 607646) PREDICTED: zinc finger ( 630) 315 41.9 0.0067
XP_016862357 (OMIM: 606042) PREDICTED: myoneurin i ( 309) 308 40.8 0.0072
XP_016862356 (OMIM: 606042) PREDICTED: myoneurin i ( 337) 308 40.8 0.0075
XP_016862355 (OMIM: 606042) PREDICTED: myoneurin i ( 468) 310 41.2 0.0077
XP_016862354 (OMIM: 606042) PREDICTED: myoneurin i ( 468) 310 41.2 0.0077
XP_005247681 (OMIM: 606042) PREDICTED: myoneurin i ( 496) 310 41.3 0.0079
XP_005247679 (OMIM: 606042) PREDICTED: myoneurin i ( 528) 310 41.3 0.0082
XP_005257223 (OMIM: 613907) PREDICTED: zinc finger ( 426) 308 41.0 0.0083
NP_001172048 (OMIM: 606042) myoneurin isoform B [H ( 581) 310 41.4 0.0085
XP_005247678 (OMIM: 606042) PREDICTED: myoneurin i ( 582) 310 41.4 0.0085
NP_001172047 (OMIM: 606042) myoneurin isoform A [H ( 610) 310 41.4 0.0087
NP_061127 (OMIM: 606042) myoneurin isoform A [Homo ( 610) 310 41.4 0.0087
XP_016862353 (OMIM: 606042) PREDICTED: myoneurin i ( 610) 310 41.4 0.0087
XP_011511289 (OMIM: 606042) PREDICTED: myoneurin i ( 610) 310 41.4 0.0087
NP_001138837 (OMIM: 613907) zinc finger protein 65 ( 606) 308 41.3 0.0098
NP_055712 (OMIM: 613907) zinc finger protein 652 [ ( 606) 308 41.3 0.0098
>>XP_011517001 (OMIM: 611692) PREDICTED: zinc finger and (504 aa)
initn: 3370 init1: 3370 opt: 3370 Z-score: 1526.5 bits: 292.0 E(85289): 2.7e-78
Smith-Waterman score: 3370; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLE
430 440 450 460 470 480
490 500
pF1KSD NDASASEMGLDSRMEIHTVSDAPD
::::::::::::::::::::::::
XP_011 NDASASEMGLDSRMEIHTVSDAPD
490 500
>>XP_005252046 (OMIM: 611692) PREDICTED: zinc finger and (514 aa)
initn: 3370 init1: 3370 opt: 3370 Z-score: 1526.5 bits: 292.0 E(85289): 2.8e-78
Smith-Waterman score: 3370; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:11-514)
10 20 30 40 50
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEECKSRVRFMSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD KAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD YCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD RESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD QAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD MNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD KKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPER
430 440 450 460 470 480
480 490 500
pF1KSD TDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
::::::::::::::::::::::::::::::::::
XP_005 TDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
490 500 510
>>NP_001092740 (OMIM: 611692) zinc finger and BTB domain (500 aa)
initn: 3347 init1: 3347 opt: 3347 Z-score: 1516.4 bits: 290.1 E(85289): 1e-77
Smith-Waterman score: 3347; 100.0% identity (100.0% similar) in 500 aa overlap (5-504:1-500)
10 20 30 40 50 60
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
10 20 30 40 50
70 80 90 100 110 120
pF1KSD FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD KCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD SSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD KMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD EAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD RERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD YHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLE
420 430 440 450 460 470
490 500
pF1KSD NDASASEMGLDSRMEIHTVSDAPD
::::::::::::::::::::::::
NP_001 NDASASEMGLDSRMEIHTVSDAPD
480 490 500
>>NP_001138810 (OMIM: 611439) zinc finger and BTB domain (634 aa)
initn: 746 init1: 411 opt: 450 Z-score: 232.8 bits: 52.9 E(85289): 3.1e-06
Smith-Waterman score: 543; 27.0% identity (52.8% similar) in 538 aa overlap (5-447:26-556)
10 20 30
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDII
. ... .. . :: .:..: .::. ::::.:::.
NP_001 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD VHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQ
...::. ::::.::::::::::.:. :. :...:. . .:..:: .:. ::::.:.
NP_001 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LKDVVSFLTAASFLQMQCVIDKCTQILE----SIHSKISVGDVDSVTVGAEENPESRNGV
:.:.:::..: ::: ..::::..:. : . :... . :::: . : . .:.
NP_001 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
160 170 180 190 200
pF1KSD KDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEE------GHSDRGSS
. ... . :....:..:. . : . : :: : ..: ..
NP_001 VAPATMGSARSHASSRASENQSPSSSN--YFSPRESTDFSSSSQEAFAASAVGSGERRGG
190 200 210 220 230
210 220 230 240 250
pF1KSD GSVSEYEIQIEGDHEQGDLLVRESQITE-------VKVKMEKSDRPSCSDSSSL------
: : . : .: ::.. ... . . : ::. . : .
NP_001 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV
240 250 260 270 280 290
260 270 280
pF1KSD -----GDDGYHTEMV----------DGEQVVA---------------VNVGSYGSVLQHA
:. : .: . :..: : ::. : .
NP_001 YVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG-GPEATLS
300 310 320 330 340 350
290 300 310 320 330
pF1KSD YSYSQAASQPTNVSEA----------FGSLSNSSPSRSMLSCFRGGRARQKRALSVH---
: .. :.: . .: :: ...: .. . :: . .. : : :
NP_001 ISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDS--GGPTPSSYAPS-HPPR
360 370 380 390 400 410
340 350 360 370
pF1KSD --LHSDLQG---LV-----QGSDSEAMMNNPGYESSPRERSARGH-----WYPY------
: :.:: :: ..:.:.: . :: .. .. : :
NP_001 PLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVP
420 430 440 450 460 470
380 390 400 410 420
pF1KSD --------NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIR
:. ..: .:::.:..:. :::. .:... :: : :.::. : .: :..
NP_001 GGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK
480 490 500 510 520 530
430 440 450 460 470 480
pF1KSD GHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDAS
:: ::..: .:.: : .. ..
NP_001 THTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESP
540 550 560 570 580 590
>>NP_005444 (OMIM: 611439) zinc finger and BTB domain-co (634 aa)
initn: 746 init1: 411 opt: 450 Z-score: 232.8 bits: 52.9 E(85289): 3.1e-06
Smith-Waterman score: 543; 27.0% identity (52.8% similar) in 538 aa overlap (5-447:26-556)
10 20 30
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDII
. ... .. . :: .:..: .::. ::::.:::.
NP_005 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD VHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQ
...::. ::::.::::::::::.:. :. :...:. . .:..:: .:. ::::.:.
NP_005 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LKDVVSFLTAASFLQMQCVIDKCTQILE----SIHSKISVGDVDSVTVGAEENPESRNGV
:.:.:::..: ::: ..::::..:. : . :... . :::: . : . .:.
NP_005 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
130 140 150 160 170 180
160 170 180 190 200
pF1KSD KDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEE------GHSDRGSS
. ... . :....:..:. . : . : :: : ..: ..
NP_005 VAPATMGSARSHASSRASENQSPSSSN--YFSPRESTDFSSSSQEAFAASAVGSGERRGG
190 200 210 220 230
210 220 230 240 250
pF1KSD GSVSEYEIQIEGDHEQGDLLVRESQITE-------VKVKMEKSDRPSCSDSSSL------
: : . : .: ::.. ... . . : ::. . : .
NP_005 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV
240 250 260 270 280 290
260 270 280
pF1KSD -----GDDGYHTEMV----------DGEQVVA---------------VNVGSYGSVLQHA
:. : .: . :..: : ::. : .
NP_005 YVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGG-GPEATLS
300 310 320 330 340 350
290 300 310 320 330
pF1KSD YSYSQAASQPTNVSEA----------FGSLSNSSPSRSMLSCFRGGRARQKRALSVH---
: .. :.: . .: :: ...: .. . :: . .. : : :
NP_005 ISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDS--GGPTPSSYAPS-HPPR
360 370 380 390 400 410
340 350 360 370
pF1KSD --LHSDLQG---LV-----QGSDSEAMMNNPGYESSPRERSARGH-----WYPY------
: :.:: :: ..:.:.: . :: .. .. : :
NP_005 PLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVP
420 430 440 450 460 470
380 390 400 410 420
pF1KSD --------NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIR
:. ..: .:::.:..:. :::. .:... :: : :.::. : .: :..
NP_005 GGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK
480 490 500 510 520 530
430 440 450 460 470 480
pF1KSD GHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDAS
:: ::..: .:.: : .. ..
NP_005 THTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESP
540 550 560 570 580 590
>>NP_862827 (OMIM: 608992) B-cell CLL/lymphoma 6 member (480 aa)
initn: 902 init1: 220 opt: 422 Z-score: 221.4 bits: 50.4 E(85289): 1.4e-05
Smith-Waterman score: 455; 27.3% identity (53.9% similar) in 466 aa overlap (18-457:20-437)
10 20 30 40 50
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASS
.:: ::..::::::.: : :. . . :::.::::::: : :
NP_862 MGSPAAPEGALGYVREFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD PYFRDHSALSTMSGLSISVIKNPNV-----FEQLLSFCYTGRMSLQLKDVVSFLTAASFL
.: .: . .:....:.. :. : ::.: ::.:. :. . . :.::..:
NP_862 GFF--YSIFRGRAGVGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYL
70 80 90 100 110
120 130 140 150 160 170
pF1KSD QMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCS
::. :.. : ..... . .... :.: :: .
NP_862 QMEHVVQACHRFIQASYEPLGIS-------------------------LRPLEAEPP--T
120 130 140 150
180 190 200 210 220
pF1KSD QGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSG----SVSEYE-IQIEGDHEQGDL
: .: : : :. .:: .: . .: . ..:. : .... :.
NP_862 PPTAPPPGSPRRSEGHPDPPTESRSCSQGPPSPASPDPKACNWKKYKYIVLNSQASQAGS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KSD LV--RESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHA
:: : : .... ..:. : :.::: .... . . : : .. ....:
NP_862 LVGERSSGQPCPQARLPSGDEASSSSSSSSSSSSEEGP-IPGPQS---RLSPTAATVQ--
220 230 240 250 260
290 300 310 320 330
pF1KSD YSYSQAASQP----TNVSEAFGSLSNSS---PSRSMLSCFRGGRARQKRALSVHLHSDLQ
.. . :: : ...... :: :. . :. ..:: :. . : :.
NP_862 FKCGAPASTPYLLTSQAQDTSGSPSERARPLPGSEFFSC-------QNCEAVAGCSSGLD
270 280 290 300 310
340 350 360 370 380 390
pF1KSD GLVQGSDSEAMMNNPGYESSPR-------ERSARGHWYPYNERLICIYCGKSFNQKGSLD
.:: : : . .. .:: : .:... ::. : :: ::. ..:
NP_862 SLVPG-DEDKPYKCQLCRSSFRYKGNLASHRTVHTGEKPYH----CSICGARFNRPANLK
320 330 340 350 360 370
400 410 420 430 440 450
pF1KSD RHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLR
: :.: : :. :. ::..... .:. :. :: .::. : :: : ::..:.:
NP_862 THSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVR
380 390 400 410 420 430
460 470 480 490 500
pF1KSD KNHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
: :
NP_862 I-HTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVHYHILGGP
440 450 460 470 480
>>XP_005259628 (OMIM: 605878) PREDICTED: zinc finger and (584 aa)
initn: 516 init1: 194 opt: 414 Z-score: 217.2 bits: 49.9 E(85289): 2.3e-05
Smith-Waterman score: 442; 26.1% identity (53.0% similar) in 536 aa overlap (11-504:9-509)
10 20 30 40 50 60
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
: . :..:: .:: ::: : :: :::... ..:. : .:..:::: : :
XP_005 MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQY
10 20 30 40 50
70 80 90 100 110
pF1KSD FRDHSALSTMSGLSISVIKNPNVFE----------QLLSFCYTGRMSLQLKDVVSFLTAA
:. : : :: .:. . ::.: :..: ::. .... .: ..:.::
XP_005 FKK---LFT-SG---AVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAA
60 70 80 90 100 110
120 130 140 150 160
pF1KSD SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSS---FF-ANPVE
.:.. : :...:. ..: .:. . .. ..:: .. . :: .::..
XP_005 RLLEIPAVSHVCADLLDRQILAADAG-ADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMN
120 130 140 150 160 170
170 180 190 200 210
pF1KSD ISPPYCSQGRQ--PTAS---SDLRMETTPSKALRSRLQEEGHSDRGS---SGSVSEYEIQ
:: . . : .. :: ...: ..:. . . . .: .. : :
XP_005 SLPPAAAAAAASFPWSAFGASDDDLDAT-KEAVAAAVAAVAAGDCNGLDFYGPGPPAERP
180 190 200 210 220
220 230 240 250 260 270
pF1KSD IEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGS
:: ..:: . . : .... : : : .:.. :
XP_005 PTGDGDEGD--------------SNPGLWPERDEDAPTG--GLFPPPV--APPAATQNGH
230 240 250 260 270
280 290 300 310 320 330
pF1KSD YG-SVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSD
:: . ..: : :.:: .: ... : ::... ... . : : . ..
XP_005 YGRGGEEEAASLSEAAPEP---GDSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVG
280 290 300 310 320
340 350 360 370 380
pF1KSD LQGLVQG-SDSEAMMNNPG-------YESSPRERSARGHWYPYNERLI-------CIYCG
: . : :: :. .. : : :. .. .. : :. : : :
XP_005 RAGAAAGDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICE
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD KSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFP
: .. :.: ::.: : : :. :..: ..::.:.:. :.: :: .::. :. :: :
XP_005 KVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFA
390 400 410 420 430 440
450 460 470 480 490
pF1KSD FQGTLNQHLRKNHPGVAEVR--SRIESPERTDVYVEQKLENDASASEMGLDSRM--EIHT
. :..:.: : :. . : .. :.: .....:..:. :. :: . ..
XP_005 HNYDLKNHMRV-HTGLRPYQCDSCCKTFVRSD-HLHRHLKKDGCN---GVPSRRGRKPRV
450 460 470 480 490 500
500
pF1KSD VSDAPD
. :::
XP_005 RGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVASPDGLGRLNVAGAGG
510 520 530 540 550 560
>>NP_056982 (OMIM: 605878) zinc finger and BTB domain-co (584 aa)
initn: 516 init1: 194 opt: 414 Z-score: 217.2 bits: 49.9 E(85289): 2.3e-05
Smith-Waterman score: 442; 26.1% identity (53.0% similar) in 536 aa overlap (11-504:9-509)
10 20 30 40 50 60
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
: . :..:: .:: ::: : :: :::... ..:. : .:..:::: : :
NP_056 MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQY
10 20 30 40 50
70 80 90 100 110
pF1KSD FRDHSALSTMSGLSISVIKNPNVFE----------QLLSFCYTGRMSLQLKDVVSFLTAA
:. : : :: .:. . ::.: :..: ::. .... .: ..:.::
NP_056 FKK---LFT-SG---AVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAA
60 70 80 90 100 110
120 130 140 150 160
pF1KSD SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSS---FF-ANPVE
.:.. : :...:. ..: .:. . .. ..:: .. . :: .::..
NP_056 RLLEIPAVSHVCADLLDRQILAADAG-ADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMN
120 130 140 150 160 170
170 180 190 200 210
pF1KSD ISPPYCSQGRQ--PTAS---SDLRMETTPSKALRSRLQEEGHSDRGS---SGSVSEYEIQ
:: . . : .. :: ...: ..:. . . . .: .. : :
NP_056 SLPPAAAAAAASFPWSAFGASDDDLDAT-KEAVAAAVAAVAAGDCNGLDFYGPGPPAERP
180 190 200 210 220
220 230 240 250 260 270
pF1KSD IEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGS
:: ..:: . . : .... : : : .:.. :
NP_056 PTGDGDEGD--------------SNPGLWPERDEDAPTG--GLFPPPV--APPAATQNGH
230 240 250 260 270
280 290 300 310 320 330
pF1KSD YG-SVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSD
:: . ..: : :.:: .: ... : ::... ... . : : . ..
NP_056 YGRGGEEEAASLSEAAPEP---GDSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVG
280 290 300 310 320
340 350 360 370 380
pF1KSD LQGLVQG-SDSEAMMNNPG-------YESSPRERSARGHWYPYNERLI-------CIYCG
: . : :: :. .. : : :. .. .. : :. : : :
NP_056 RAGAAAGDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICE
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD KSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFP
: .. :.: ::.: : : :. :..: ..::.:.:. :.: :: .::. :. :: :
NP_056 KVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFA
390 400 410 420 430 440
450 460 470 480 490
pF1KSD FQGTLNQHLRKNHPGVAEVR--SRIESPERTDVYVEQKLENDASASEMGLDSRM--EIHT
. :..:.: : :. . : .. :.: .....:..:. :. :: . ..
NP_056 HNYDLKNHMRV-HTGLRPYQCDSCCKTFVRSD-HLHRHLKKDGCN---GVPSRRGRKPRV
450 460 470 480 490 500
500
pF1KSD VSDAPD
. :::
NP_056 RGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVASPDGLGRLNVAGAGG
510 520 530 540 550 560
>>NP_001304919 (OMIM: 605878) zinc finger and BTB domain (584 aa)
initn: 516 init1: 194 opt: 414 Z-score: 217.2 bits: 49.9 E(85289): 2.3e-05
Smith-Waterman score: 442; 26.1% identity (53.0% similar) in 536 aa overlap (11-504:9-509)
10 20 30 40 50 60
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
: . :..:: .:: ::: : :: :::... ..:. : .:..:::: : :
NP_001 MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQY
10 20 30 40 50
70 80 90 100 110
pF1KSD FRDHSALSTMSGLSISVIKNPNVFE----------QLLSFCYTGRMSLQLKDVVSFLTAA
:. : : :: .:. . ::.: :..: ::. .... .: ..:.::
NP_001 FKK---LFT-SG---AVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAA
60 70 80 90 100 110
120 130 140 150 160
pF1KSD SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSS---FF-ANPVE
.:.. : :...:. ..: .:. . .. ..:: .. . :: .::..
NP_001 RLLEIPAVSHVCADLLDRQILAADAG-ADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMN
120 130 140 150 160 170
170 180 190 200 210
pF1KSD ISPPYCSQGRQ--PTAS---SDLRMETTPSKALRSRLQEEGHSDRGS---SGSVSEYEIQ
:: . . : .. :: ...: ..:. . . . .: .. : :
NP_001 SLPPAAAAAAASFPWSAFGASDDDLDAT-KEAVAAAVAAVAAGDCNGLDFYGPGPPAERP
180 190 200 210 220
220 230 240 250 260 270
pF1KSD IEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGS
:: ..:: . . : .... : : : .:.. :
NP_001 PTGDGDEGD--------------SNPGLWPERDEDAPTG--GLFPPPV--APPAATQNGH
230 240 250 260 270
280 290 300 310 320 330
pF1KSD YG-SVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSD
:: . ..: : :.:: .: ... : ::... ... . : : . ..
NP_001 YGRGGEEEAASLSEAAPEP---GDSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVG
280 290 300 310 320
340 350 360 370 380
pF1KSD LQGLVQG-SDSEAMMNNPG-------YESSPRERSARGHWYPYNERLI-------CIYCG
: . : :: :. .. : : :. .. .. : :. : : :
NP_001 RAGAAAGDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICE
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD KSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFP
: .. :.: ::.: : : :. :..: ..::.:.:. :.: :: .::. :. :: :
NP_001 KVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFA
390 400 410 420 430 440
450 460 470 480 490
pF1KSD FQGTLNQHLRKNHPGVAEVR--SRIESPERTDVYVEQKLENDASASEMGLDSRM--EIHT
. :..:.: : :. . : .. :.: .....:..:. :. :: . ..
NP_001 HNYDLKNHMRV-HTGLRPYQCDSCCKTFVRSD-HLHRHLKKDGCN---GVPSRRGRKPRV
450 460 470 480 490 500
500
pF1KSD VSDAPD
. :::
NP_001 RGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVASPDGLGRLNVAGAGG
510 520 530 540 550 560
>>XP_005259627 (OMIM: 605878) PREDICTED: zinc finger and (634 aa)
initn: 516 init1: 194 opt: 414 Z-score: 216.9 bits: 50.0 E(85289): 2.4e-05
Smith-Waterman score: 442; 26.1% identity (53.0% similar) in 536 aa overlap (11-504:59-559)
10 20 30 40
pF1KSD MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIV
: . :..:: .:: ::: : :: :::...
XP_005 WGSWGWKGATSDRLHVQVSARKMAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVI
30 40 50 60 70 80
50 60 70 80 90
pF1KSD HIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFE----------QLLSF
..:. : .:..:::: : ::. : : :: .:. . ::.: :..:
XP_005 LVEGREFPTHRSVLAACSQYFKK---LFT-SG---AVVDQQNVYEIDFVSAEALTALMDF
90 100 110 120 130 140
100 110 120 130 140 150
pF1KSD CYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPE
::. .... .: ..:.:: .:.. : :...:. ..: .:. . .. .
XP_005 AYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLDRQILAADAG-ADAGQLDLVDQID
150 160 170 180 190 200
160 170 180 190 200
pF1KSD SRNGVKDSS---FF-ANPVEISPPYCSQGRQ--PTAS---SDLRMETTPSKALRSRLQEE
.:: .. . :: .::.. :: . . : .. :: ...: ..:. . .
XP_005 QRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASFPWSAFGASDDDLDAT-KEAVAAAVAAV
210 220 230 240 250
210 220 230 240 250
pF1KSD GHSDRGS---SGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGD
. .: .. : : :: ..:: . . : .... :
XP_005 AAGDCNGLDFYGPGPPAERPPTGDGDEGD--------------SNPGLWPERDEDAPTG-
260 270 280 290 300
260 270 280 290 300 310
pF1KSD DGYHTEMVDGEQVVAVNVGSYG-SVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLS
: : .:.. : :: . ..: : :.:: .: ... : ::... ... .
XP_005 -GLFPPPV--APPAATQNGHYGRGGEEEAASLSEAAPEP---GDSPGFLSGAAEGEDGDG
310 320 330 340 350
320 330 340 350 360
pF1KSD CFRGGRARQKRALSVHLHSDLQGLVQG-SDSEAMMNNPG-------YESSPRERSARGHW
: : . .. : . : :: :. .. : : :. .. .. :
XP_005 PDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAW
360 370 380 390 400 410
370 380 390 400 410 420
pF1KSD YPYNERLI-------CIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYH
:. : : : : .. :.: ::.: : : :. :..: ..::.:.:. :
XP_005 SQKVEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVH
420 430 440 450 460 470
430 440 450 460 470 480
pF1KSD IRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVR--SRIESPERTDVYVEQKLE
.: :: .::. :. :: : . :..:.: : :. . : .. :.: .....:.
XP_005 MRKHTGEKPYLCQQCGAAFAHNYDLKNHMRV-HTGLRPYQCDSCCKTFVRSD-HLHRHLK
480 490 500 510 520 530
490 500
pF1KSD NDASASEMGLDSRM--EIHTVSDAPD
.:. :. :: . .. . :::
XP_005 KDGCN---GVPSRRGRKPRVRGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDE
540 550 560 570 580 590
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:56:29 2016 done: Thu Nov 3 07:56:30 2016
Total Scan time: 8.870 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]