FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1994, 1073 aa 1>>>pF1KSDA1994 1073 - 1073 aa - 1073 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.0545+/-0.000463; mu= -18.1790+/- 0.029 mean_var=503.6631+/-108.880, 0's: 0 Z-trim(123.2): 171 B-trim: 3353 in 2/56 Lambda= 0.057148 statistics sampled from 42426 (42659) to 42426 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.5), width: 16 Scan time: 17.390 The best scores are: opt bits E(85289) NP_904358 (OMIM: 607715) TSC22 domain family prote (1073) 6910 585.1 7.3e-166 XP_005266640 (OMIM: 607715) PREDICTED: TSC22 domai (1028) 6276 532.8 3.8e-150 XP_016876299 (OMIM: 607715) PREDICTED: TSC22 domai (1048) 6276 532.8 3.9e-150 XP_016876300 (OMIM: 607715) PREDICTED: TSC22 domai ( 985) 6270 532.3 5.2e-150 NP_001230728 (OMIM: 607715) TSC22 domain family pr ( 570) 3592 311.4 9.8e-84 NP_006013 (OMIM: 607715) TSC22 domain family prote ( 144) 653 68.6 2.8e-11 NP_001230727 (OMIM: 607715) TSC22 domain family pr ( 86) 548 59.8 7.6e-09 NP_001230726 (OMIM: 607715) TSC22 domain family pr ( 86) 548 59.8 7.6e-09 NP_001289972 (OMIM: 611914) TSC22 domain family pr ( 395) 442 51.5 1.1e-05 NP_112197 (OMIM: 611914) TSC22 domain family prote ( 395) 442 51.5 1.1e-05 NP_004080 (OMIM: 300506) TSC22 domain family prote ( 134) 412 48.8 2.6e-05 XP_005262157 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 XP_005262160 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 XP_005262156 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 XP_011529186 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 XP_005262159 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 NP_001305399 (OMIM: 300506) TSC22 domain family pr ( 200) 404 48.2 5.6e-05 NP_932174 (OMIM: 300506) TSC22 domain family prote ( 200) 404 48.2 5.6e-05 XP_016884824 (OMIM: 300506) PREDICTED: TSC22 domai ( 200) 404 48.2 5.6e-05 NP_001305397 (OMIM: 300506) TSC22 domain family pr ( 200) 404 48.2 5.6e-05 XP_006724326 (OMIM: 607372) PREDICTED: mediator of ( 717) 364 45.3 0.0015 XP_016884308 (OMIM: 607372) PREDICTED: mediator of ( 707) 363 45.2 0.0016 XP_006724327 (OMIM: 607372) PREDICTED: mediator of ( 707) 363 45.2 0.0016 XP_016884307 (OMIM: 607372) PREDICTED: mediator of ( 707) 363 45.2 0.0016 XP_011528517 (OMIM: 607372) PREDICTED: mediator of ( 741) 363 45.2 0.0017 XP_016884306 (OMIM: 607372) PREDICTED: mediator of ( 749) 363 45.2 0.0017 XP_011528516 (OMIM: 607372) PREDICTED: mediator of ( 762) 363 45.2 0.0017 NP_001003891 (OMIM: 607372) mediator of RNA polyme ( 788) 363 45.2 0.0018 XP_016883233 (OMIM: 605299) PREDICTED: nuclear rec (2051) 359 45.2 0.0048 XP_011527029 (OMIM: 605299) PREDICTED: nuclear rec (2056) 359 45.2 0.0048 XP_011527028 (OMIM: 605299) PREDICTED: nuclear rec (2057) 358 45.1 0.0051 NP_001015881 (OMIM: 300506) TSC22 domain family pr ( 77) 311 40.3 0.0053 >>NP_904358 (OMIM: 607715) TSC22 domain family protein 1 (1073 aa) initn: 6910 init1: 6910 opt: 6910 Z-score: 3098.8 bits: 585.1 E(85289): 7.3e-166 Smith-Waterman score: 6910; 99.9% identity (100.0% similar) in 1073 aa overlap (1-1073:1-1073) 10 20 30 40 50 60 pF1KSD MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIGINSVTGTSTVNNVNITAVGSFNPNVTSSILGNVNISTSNIPSAAGVSVGPGVTSGVN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_904 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KSD EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 1030 1040 1050 1060 1070 >>XP_005266640 (OMIM: 607715) PREDICTED: TSC22 domain fa (1028 aa) initn: 6439 init1: 6276 opt: 6276 Z-score: 2816.6 bits: 532.8 E(85289): 3.8e-150 Smith-Waterman score: 6276; 99.8% identity (100.0% similar) in 973 aa overlap (1-973:1-973) 10 20 30 40 50 60 pF1KSD MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIGINSVTGTSTVNNVNITAVGSFNPNVTSSILGNVNISTSNIPSAAGVSVGPGVTSGVN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_005 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL :::::::::::.: XP_005 TTPLVDGEDESASLLPEVQGVILEPQIQPRPRRAFDVRGPLSPLNPWRQNIQLLERVGKD 970 980 990 1000 1010 1020 >>XP_016876299 (OMIM: 607715) PREDICTED: TSC22 domain fa (1048 aa) initn: 6439 init1: 6276 opt: 6276 Z-score: 2816.4 bits: 532.8 E(85289): 3.9e-150 Smith-Waterman score: 6276; 99.8% identity (100.0% similar) in 973 aa overlap (1-973:1-973) 10 20 30 40 50 60 pF1KSD MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIGINSVTGTSTVNNVNITAVGSFNPNVTSSILGNVNISTSNIPSAAGVSVGPGVTSGVN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_016 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL :::::::::::.: XP_016 TTPLVDGEDESASLLPEVQGVILEPQIQPRPRRAFDVRGPLSPLNPWRQNIQLLERVGKD 970 980 990 1000 1010 1020 >>XP_016876300 (OMIM: 607715) PREDICTED: TSC22 domain fa (985 aa) initn: 6270 init1: 6270 opt: 6270 Z-score: 2814.2 bits: 532.3 E(85289): 5.2e-150 Smith-Waterman score: 6270; 99.9% identity (100.0% similar) in 971 aa overlap (1-971:1-971) 10 20 30 40 50 60 pF1KSD MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIGINSVTGTSTVNNVNITAVGSFNPNVTSSILGNVNISTSNIPSAAGVSVGPGVTSGVN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_016 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL ::::::::::: XP_016 TTPLVDGEDESFWYISKLAGRARRK 970 980 >>NP_001230728 (OMIM: 607715) TSC22 domain family protei (570 aa) initn: 3592 init1: 3592 opt: 3592 Z-score: 1624.3 bits: 311.4 E(85289): 9.8e-84 Smith-Waterman score: 3592; 99.8% identity (100.0% similar) in 556 aa overlap (1-556:1-556) 10 20 30 40 50 60 pF1KSD MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIGINSVTGTSTVNNVNITAVGSFNPNVTSSILGNVNISTSNIPSAAGVSVGPGVTSGVN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_001 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL :::::::::::::::: NP_001 QSQISQVQLQSQELSYLTMKVVLLIVYLCM 550 560 570 >>NP_006013 (OMIM: 607715) TSC22 domain family protein 1 (144 aa) initn: 653 init1: 653 opt: 653 Z-score: 323.3 bits: 68.6 E(85289): 2.8e-11 Smith-Waterman score: 653; 99.0% identity (100.0% similar) in 105 aa overlap (969-1073:40-144) 940 950 960 970 980 990 pF1KSD SDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYA :.:::::::::::::::::::::::::::: NP_006 AMDLGVYQLRHFSISFLSSLLGTENASVRLDNSSSGASVVAIDNKIEQAMDLVKSHLMYA 10 20 30 40 50 60 1000 1010 1020 1030 1040 1050 pF1KSD VREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTT 70 80 90 100 110 120 1060 1070 pF1KSD QPPAQPASQGSGPTA ::::::::::::::: NP_006 QPPAQPASQGSGPTA 130 140 >>NP_001230727 (OMIM: 607715) TSC22 domain family protei (86 aa) initn: 548 init1: 548 opt: 548 Z-score: 279.8 bits: 59.8 E(85289): 7.6e-09 Smith-Waterman score: 548; 100.0% identity (100.0% similar) in 86 aa overlap (988-1073:1-86) 960 970 980 990 1000 1010 pF1KSD LPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKN :::::::::::::::::::::::::::::: NP_001 MDLVKSHLMYAVREEVEVLKEQIKELIEKN 10 20 30 1020 1030 1040 1050 1060 1070 pF1KSD SQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 40 50 60 70 80 >>NP_001230726 (OMIM: 607715) TSC22 domain family protei (86 aa) initn: 548 init1: 548 opt: 548 Z-score: 279.8 bits: 59.8 E(85289): 7.6e-09 Smith-Waterman score: 548; 100.0% identity (100.0% similar) in 86 aa overlap (988-1073:1-86) 960 970 980 990 1000 1010 pF1KSD LPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKN :::::::::::::::::::::::::::::: NP_001 MDLVKSHLMYAVREEVEVLKEQIKELIEKN 10 20 30 1020 1030 1040 1050 1060 1070 pF1KSD SQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 40 50 60 70 80 >>NP_001289972 (OMIM: 611914) TSC22 domain family protei (395 aa) initn: 512 init1: 314 opt: 442 Z-score: 223.0 bits: 51.5 E(85289): 1.1e-05 Smith-Waterman score: 442; 30.7% identity (57.5% similar) in 391 aa overlap (676-1054:21-393) 650 660 670 680 690 700 pF1KSD KSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA-GTTVIPVAQPQGIQLPVQPTAVPAQ : :. :.. :. :: : :.. :. NP_001 MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSP 10 20 30 40 50 710 720 730 740 750 760 pF1KSD PAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQV :.. : . .: : :. . . . ...: .. .: . . .. . NP_001 DPGGKGTPRNGSP------PPGAPSSRF-RVVKLPHGLGEPYRRGRWTCVDV----YERD 60 70 80 90 770 780 790 800 810 pF1KSD VPPAQTGIIHQGVQTSAP-----SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQ-QL . : . : . .:.. .. :: ..: .:: . : .: :.:. .:: .: . NP_001 LEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLG--LGAPTPPSGL---SQGPTSWLRP 100 110 120 130 140 150 820 830 840 850 860 870 pF1KSD PAVSSLPSASSISV-TSQVSSTGPSGMPSAPTNLVPPQNIAQTPAT--QNGNLVQSVSQP : .: :.: :.. .:. . . . : . ::. : : . :. .. : NP_001 PPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLP 160 170 180 190 200 210 880 890 900 910 920 930 pF1KSD PL-IATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGG : . .... :. ::: . . : . .:. : .. : . : ... NP_001 SLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDAS 220 230 240 250 260 270 940 950 960 970 980 990 pF1KSD MSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSH . : ...::. . ..: .. : :..:.:.:: :.:.::::::::::::::: NP_001 LVHKSPDPFGAVAAQKFSLAHSMLAISGHL-DSDDDSGSG-SLVGIDNKIEQAMDLVKSH 280 290 300 310 320 330 1000 1010 1020 1030 1040 1050 pF1KSD LMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQ-LQTGSPPATTQ ::.:::::::::::::.:: :.:. :::::.::..:::::::::. .. . .::: . NP_001 LMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNG 340 350 360 370 380 390 1060 1070 pF1KSD PQGTTQPPAQPASQGSGPTA : NP_001 PSV >>NP_112197 (OMIM: 611914) TSC22 domain family protein 4 (395 aa) initn: 512 init1: 314 opt: 442 Z-score: 223.0 bits: 51.5 E(85289): 1.1e-05 Smith-Waterman score: 442; 30.7% identity (57.5% similar) in 391 aa overlap (676-1054:21-393) 650 660 670 680 690 700 pF1KSD KSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA-GTTVIPVAQPQGIQLPVQPTAVPAQ : :. :.. :. :: : :.. :. NP_112 MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSP 10 20 30 40 50 710 720 730 740 750 760 pF1KSD PAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQV :.. : . .: : :. . . . ...: .. .: . . .. . NP_112 DPGGKGTPRNGSP------PPGAPSSRF-RVVKLPHGLGEPYRRGRWTCVDV----YERD 60 70 80 90 770 780 790 800 810 pF1KSD VPPAQTGIIHQGVQTSAP-----SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQ-QL . : . : . .:.. .. :: ..: .:: . : .: :.:. .:: .: . NP_112 LEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLG--LGAPTPPSGL---SQGPTSWLRP 100 110 120 130 140 150 820 830 840 850 860 870 pF1KSD PAVSSLPSASSISV-TSQVSSTGPSGMPSAPTNLVPPQNIAQTPAT--QNGNLVQSVSQP : .: :.: :.. .:. . . . : . ::. : : . :. .. : NP_112 PPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLP 160 170 180 190 200 210 880 890 900 910 920 930 pF1KSD PL-IATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGG : . .... :. ::: . . : . .:. : .. : . : ... NP_112 SLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDAS 220 230 240 250 260 270 940 950 960 970 980 990 pF1KSD MSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSH . : ...::. . ..: .. : :..:.:.:: :.:.::::::::::::::: NP_112 LVHKSPDPFGAVAAQKFSLAHSMLAISGHL-DSDDDSGSG-SLVGIDNKIEQAMDLVKSH 280 290 300 310 320 330 1000 1010 1020 1030 1040 1050 pF1KSD LMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQ-LQTGSPPATTQ ::.:::::::::::::.:: :.:. :::::.::..:::::::::. .. . .::: . NP_112 LMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNG 340 350 360 370 380 390 1060 1070 pF1KSD PQGTTQPPAQPASQGSGPTA : NP_112 PSV 1073 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:57:14 2016 done: Thu Nov 3 07:57:17 2016 Total Scan time: 17.390 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]