FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA2005, 1584 aa 1>>>pF1KSDA2005 1584 - 1584 aa - 1584 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2786+/-0.000594; mu= 19.0789+/- 0.037 mean_var=88.8228+/-18.146, 0's: 0 Z-trim(107.2): 33 B-trim: 272 in 2/49 Lambda= 0.136086 statistics sampled from 15213 (15226) to 15213 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.506), E-opt: 0.2 (0.179), width: 16 Scan time: 14.040 The best scores are: opt bits E(85289) XP_005250250 (OMIM: 159550,611170) PREDICTED: ster (1584) 10487 2070.7 0 XP_016867312 (OMIM: 159550,611170) PREDICTED: ster (1584) 10487 2070.7 0 NP_001290429 (OMIM: 159550,611170) sterile alpha m (1584) 10487 2070.7 0 XP_006715953 (OMIM: 159550,611170) PREDICTED: ster (1584) 10487 2070.7 0 NP_001290425 (OMIM: 159550,611170) sterile alpha m (1584) 10487 2070.7 0 NP_001290427 (OMIM: 159550,611170) sterile alpha m (1584) 10487 2070.7 0 XP_016867311 (OMIM: 159550,611170) PREDICTED: ster (1584) 10487 2070.7 0 XP_011514205 (OMIM: 159550,611170) PREDICTED: ster (1584) 10487 2070.7 0 NP_689916 (OMIM: 159550,611170) sterile alpha moti (1584) 10487 2070.7 0 NP_001290426 (OMIM: 159550,611170) sterile alpha m (1584) 10487 2070.7 0 NP_060124 (OMIM: 610455,610456,617053) sterile alp (1589) 5307 1053.7 0 NP_001180236 (OMIM: 610455,610456,617053) sterile (1589) 5307 1053.7 0 >>XP_005250250 (OMIM: 159550,611170) PREDICTED: sterile (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: XP_005 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>XP_016867312 (OMIM: 159550,611170) PREDICTED: sterile (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: XP_016 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>NP_001290429 (OMIM: 159550,611170) sterile alpha motif (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: NP_001 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>XP_006715953 (OMIM: 159550,611170) PREDICTED: sterile (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: XP_006 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>NP_001290425 (OMIM: 159550,611170) sterile alpha motif (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: NP_001 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>NP_001290427 (OMIM: 159550,611170) sterile alpha motif (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: NP_001 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>XP_016867311 (OMIM: 159550,611170) PREDICTED: sterile (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: XP_016 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>XP_011514205 (OMIM: 159550,611170) PREDICTED: sterile (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: XP_011 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>NP_689916 (OMIM: 159550,611170) sterile alpha motif do (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: NP_689 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 >>NP_001290426 (OMIM: 159550,611170) sterile alpha motif (1584 aa) initn: 10487 init1: 10487 opt: 10487 Z-score: 11121.4 bits: 2070.7 E(85289): 0 Smith-Waterman score: 10487; 100.0% identity (100.0% similar) in 1584 aa overlap (1-1584:1-1584) 10 20 30 40 50 60 pF1KSD MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKES 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KSD NIERVSFYLGFSIEGPLAYDIEVI :::::::::::::::::::::::: NP_001 NIERVSFYLGFSIEGPLAYDIEVI 1570 1580 1584 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 07:59:17 2016 done: Thu Nov 3 07:59:19 2016 Total Scan time: 14.040 Total Display time: 1.060 Function used was FASTA [36.3.4 Apr, 2011]