FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0004, 1086 aa 1>>>pF1KSDB0004 1086 - 1086 aa - 1086 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2761+/-0.000996; mu= -3.5509+/- 0.060 mean_var=353.4685+/-70.044, 0's: 0 Z-trim(115.7): 27 B-trim: 0 in 0/53 Lambda= 0.068218 statistics sampled from 16228 (16252) to 16228 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.499), width: 16 Scan time: 5.780 The best scores are: opt bits E(32554) CCDS10410.1 CAPN15 gene_id:6650|Hs108|chr16 (1086) 7635 766.0 0 CCDS47436.1 CAPN11 gene_id:11131|Hs108|chr6 ( 739) 560 69.6 3e-11 >>CCDS10410.1 CAPN15 gene_id:6650|Hs108|chr16 (1086 aa) initn: 7635 init1: 7635 opt: 7635 Z-score: 4076.4 bits: 766.0 E(32554): 0 Smith-Waterman score: 7635; 100.0% identity (100.0% similar) in 1086 aa overlap (1-1086:1-1086) 10 20 30 40 50 60 pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD DSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGL 1030 1040 1050 1060 1070 1080 pF1KSD HGPRPL :::::: CCDS10 HGPRPL >>CCDS47436.1 CAPN11 gene_id:11131|Hs108|chr6 (739 aa) initn: 549 init1: 206 opt: 560 Z-score: 315.5 bits: 69.6 E(32554): 3e-11 Smith-Waterman score: 586; 35.1% identity (59.6% similar) in 342 aa overlap (474-795:66-380) 450 460 470 480 490 500 pF1KSD QRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGF- .:.. : : ... : : :: : :.:: CCDS47 TGMVAHINNSRLKAKGVGQHDNAQNFGNQSFEELRAACLRKGELFEDPLFPAEPSSLGFK 40 50 60 70 80 90 510 520 530 540 550 pF1KSD ---PAGDSVQQRVRQWLRPQEI-NCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSAL : . .::. .: ::..: : .: .. . :.:: ::.::.::.:.:. CCDS47 DLGPNSKNVQNI--SWQRPKDIINNPLF--------IMDGISPTDICQGILGDCWLLAAI 100 110 120 130 140 560 570 580 590 600 610 pF1KSD AVLAERPDLVERVMVTRSLCAE----GAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQ . :. : :. :: : :. . : .. .. . : :..:.::: :: . .. . CCDS47 GSLTTCPKLLYRV-VPRGQSFKKNYAGIFHFQIWQFGQWVNVVVDDRLPTKNDKLVFVHS 150 160 170 180 190 200 620 630 640 650 660 670 pF1KSD AQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVD ..:...: ::.::: ::: ::: ::..: ..::: .::. .:. :: . : . CCDS47 TERSEFWSALLEKAYAKLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQ-------RPPQN 210 220 230 240 250 680 690 700 710 720 pF1KSD TDLIWAKMLSSKEAGFLMGASCGGGNMKV-DDSAYESLG---LRPRHAYSILDVRDVQ-- . : . : . ::: : ..: .:: ::. : ::::. ..::. CCDS47 LLRLLRKAV---ERSSLMGCS-----IEVTSDSELESMTDKMLVRGHAYSVTGLQDVHYR 260 270 280 290 300 730 740 750 760 770 780 pF1KSD GT--RLLRLRNPWGRFSWNGSWSD---EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRY : :.:.::::::. :::.::: :: . . .. .:. : . .: ::: : ::. CCDS47 GKMETLIRVRNPWGRIEWNGAWSDSAREWEEVASDIQMQLL-HKTEDGEFWMSYQDFLNN 310 320 330 340 350 360 790 800 810 820 830 840 pF1KSD FDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDAVDS : ..::.. : CCDS47 FTLLEICNLTPDTLSGDYKSYWHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEG 370 380 390 400 410 420 1086 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:02:45 2016 done: Thu Nov 3 08:02:46 2016 Total Scan time: 5.780 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]