FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0030, 1606 aa 1>>>pF1KSDB0030 1606 - 1606 aa - 1606 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.9714+/-0.000472; mu= -20.8820+/- 0.029 mean_var=592.4953+/-121.803, 0's: 0 Z-trim(123.2): 139 B-trim: 0 in 0/62 Lambda= 0.052690 statistics sampled from 42439 (42588) to 42439 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.499), width: 16 Scan time: 18.900 The best scores are: opt bits E(85289) NP_001181876 (OMIM: 600495,614251) eukaryotic tran (1606) 10682 828.3 0 NP_001181875 (OMIM: 600495,614251) eukaryotic tran (1606) 10682 828.3 0 NP_937884 (OMIM: 600495,614251) eukaryotic transla (1599) 10610 822.9 0 NP_886553 (OMIM: 600495,614251) eukaryotic transla (1600) 10598 821.9 0 NP_001278086 (OMIM: 600495,614251) eukaryotic tran (1559) 10320 800.8 0 NP_937887 (OMIM: 600495,614251) eukaryotic transla (1512) 10017 777.8 0 NP_937885 (OMIM: 600495,614251) eukaryotic transla (1435) 9476 736.6 3.5e-211 NP_004944 (OMIM: 600495,614251) eukaryotic transla (1404) 9246 719.1 6.4e-206 XP_016858183 (OMIM: 603929) PREDICTED: eukaryotic (1603) 2340 194.2 7.6e-48 XP_016858184 (OMIM: 603929) PREDICTED: eukaryotic (1602) 2331 193.5 1.2e-47 XP_016858185 (OMIM: 603929) PREDICTED: eukaryotic (1596) 2329 193.4 1.4e-47 XP_016858187 (OMIM: 603929) PREDICTED: eukaryotic (1592) 2320 192.7 2.2e-47 XP_016858186 (OMIM: 603929) PREDICTED: eukaryotic (1595) 2320 192.7 2.2e-47 XP_016858167 (OMIM: 603929) PREDICTED: eukaryotic (1641) 2317 192.5 2.6e-47 XP_016858189 (OMIM: 603929) PREDICTED: eukaryotic (1585) 2312 192.1 3.3e-47 NP_003751 (OMIM: 603929) eukaryotic translation in (1585) 2312 192.1 3.3e-47 XP_011540663 (OMIM: 603929) PREDICTED: eukaryotic (1640) 2308 191.8 4.2e-47 NP_001185731 (OMIM: 603929) eukaryotic translation (1591) 2307 191.7 4.3e-47 XP_016858190 (OMIM: 603929) PREDICTED: eukaryotic (1584) 2299 191.1 6.6e-47 XP_016858174 (OMIM: 603929) PREDICTED: eukaryotic (1630) 2299 191.1 6.7e-47 XP_016858171 (OMIM: 603929) PREDICTED: eukaryotic (1633) 2299 191.1 6.7e-47 XP_016858180 (OMIM: 603929) PREDICTED: eukaryotic (1623) 2297 190.9 7.4e-47 XP_016858175 (OMIM: 603929) PREDICTED: eukaryotic (1629) 2290 190.4 1.1e-46 XP_016858192 (OMIM: 603929) PREDICTED: eukaryotic (1537) 2288 190.2 1.1e-46 XP_016858193 (OMIM: 603929) PREDICTED: eukaryotic (1536) 2279 189.5 1.8e-46 NP_001185730 (OMIM: 603929) eukaryotic translation (1621) 2215 184.7 5.6e-45 XP_016858179 (OMIM: 603929) PREDICTED: eukaryotic (1628) 2215 184.7 5.6e-45 XP_016858170 (OMIM: 603929) PREDICTED: eukaryotic (1639) 2215 184.7 5.6e-45 XP_016858163 (OMIM: 603929) PREDICTED: eukaryotic (1670) 2215 184.7 5.7e-45 XP_011540658 (OMIM: 603929) PREDICTED: eukaryotic (1677) 2215 184.7 5.7e-45 XP_016858181 (OMIM: 603929) PREDICTED: eukaryotic (1622) 2207 184.1 8.5e-45 XP_016858182 (OMIM: 603929) PREDICTED: eukaryotic (1622) 2207 184.1 8.5e-45 XP_011540676 (OMIM: 603929) PREDICTED: eukaryotic (1622) 2207 184.1 8.5e-45 XP_011540677 (OMIM: 603929) PREDICTED: eukaryotic (1622) 2207 184.1 8.5e-45 XP_016858176 (OMIM: 603929) PREDICTED: eukaryotic (1629) 2207 184.1 8.5e-45 XP_016858177 (OMIM: 603929) PREDICTED: eukaryotic (1629) 2207 184.1 8.5e-45 XP_016858173 (OMIM: 603929) PREDICTED: eukaryotic (1633) 2207 184.1 8.6e-45 XP_016858172 (OMIM: 603929) PREDICTED: eukaryotic (1633) 2207 184.1 8.6e-45 XP_011540673 (OMIM: 603929) PREDICTED: eukaryotic (1633) 2207 184.1 8.6e-45 XP_016858168 (OMIM: 603929) PREDICTED: eukaryotic (1640) 2207 184.1 8.6e-45 XP_016858169 (OMIM: 603929) PREDICTED: eukaryotic (1640) 2207 184.1 8.6e-45 XP_016858165 (OMIM: 603929) PREDICTED: eukaryotic (1660) 2207 184.1 8.7e-45 XP_016858166 (OMIM: 603929) PREDICTED: eukaryotic (1660) 2207 184.1 8.7e-45 XP_016858164 (OMIM: 603929) PREDICTED: eukaryotic (1667) 2207 184.1 8.7e-45 XP_016858162 (OMIM: 603929) PREDICTED: eukaryotic (1671) 2207 184.1 8.7e-45 XP_011540672 (OMIM: 603929) PREDICTED: eukaryotic (1678) 2207 184.1 8.7e-45 XP_016858161 (OMIM: 603929) PREDICTED: eukaryotic (1678) 2207 184.1 8.7e-45 XP_016858191 (OMIM: 603929) PREDICTED: eukaryotic (1562) 2189 182.7 2.1e-44 XP_016858196 (OMIM: 603929) PREDICTED: eukaryotic (1342) 2163 180.7 7.4e-44 XP_016858194 (OMIM: 603929) PREDICTED: eukaryotic (1398) 2159 180.4 9.5e-44 >>NP_001181876 (OMIM: 600495,614251) eukaryotic translat (1606 aa) initn: 10682 init1: 10682 opt: 10682 Z-score: 4407.0 bits: 828.3 E(85289): 0 Smith-Waterman score: 10682; 99.9% identity (100.0% similar) in 1606 aa overlap (1-1606:1-1606) 10 20 30 40 50 60 pF1KSD MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_001 DLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 pF1KSD VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1570 1580 1590 1600 >>NP_001181875 (OMIM: 600495,614251) eukaryotic translat (1606 aa) initn: 10682 init1: 10682 opt: 10682 Z-score: 4407.0 bits: 828.3 E(85289): 0 Smith-Waterman score: 10682; 99.9% identity (100.0% similar) in 1606 aa overlap (1-1606:1-1606) 10 20 30 40 50 60 pF1KSD MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_001 DLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 pF1KSD VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1570 1580 1590 1600 >>NP_937884 (OMIM: 600495,614251) eukaryotic translation (1599 aa) initn: 10286 init1: 10286 opt: 10610 Z-score: 4377.5 bits: 822.9 E(85289): 0 Smith-Waterman score: 10610; 99.5% identity (99.6% similar) in 1606 aa overlap (1-1606:1-1599) 10 20 30 40 50 60 pF1KSD MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP ::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_937 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ-------HFYP 10 20 30 40 50 70 80 90 100 110 120 pF1KSD SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD DLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_937 DLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARR 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKP 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEE 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 HREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKIT 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KSD KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTE 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KSD STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 STDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEER 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KSD SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEY 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTA 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAA 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KSD SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAP 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KSD GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIF 1440 1450 1460 1470 1480 1490 1510 1520 1530 1540 1550 1560 pF1KSD ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDED 1500 1510 1520 1530 1540 1550 1570 1580 1590 1600 pF1KSD VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::::::::::::: NP_937 VVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1560 1570 1580 1590 >>NP_886553 (OMIM: 600495,614251) eukaryotic translation (1600 aa) initn: 10272 init1: 5898 opt: 10598 Z-score: 4372.5 bits: 821.9 E(85289): 0 Smith-Waterman score: 10598; 99.4% identity (99.5% similar) in 1607 aa overlap (1-1606:1-1600) 10 20 30 40 50 60 pF1KSD MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYP ::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_886 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ-------HFYP 10 20 30 40 50 70 80 90 100 110 120 pF1KSD SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 SRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD DLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_886 DLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 AESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQK 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 YEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLD 600 610 620 630 640 650 670 680 690 700 710 pF1KSD PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGP-AGLGPRRSQQGPRKEP ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: NP_886 PTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPQAGLGPRRSQQGPRKEP 660 670 680 690 700 710 720 730 740 750 760 770 pF1KSD RKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 RKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT 720 730 740 750 760 770 780 790 800 810 820 830 pF1KSD PQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 PQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEK 780 790 800 810 820 830 840 850 860 870 880 890 pF1KSD PTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 PTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIAR 840 850 860 870 880 890 900 910 920 930 940 950 pF1KSD RRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 RRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAK 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD PRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 PRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEME 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KSD EHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 EHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKI 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KSD TKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 TKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KSD ESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 ESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEE 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KSD RSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 RSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEE 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KSD YLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 YLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLST 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD AQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 AQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKA 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KSD ASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 ASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEA 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KSD PGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 PGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 pF1KSD FETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_886 FETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDE 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 pF1KSD DVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN ::::::::::::::::::::::::::::::::::::::::::::::: NP_886 DVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1560 1570 1580 1590 1600 >>NP_001278086 (OMIM: 600495,614251) eukaryotic translat (1559 aa) initn: 10286 init1: 10286 opt: 10320 Z-score: 4258.5 bits: 800.8 E(85289): 0 Smith-Waterman score: 10320; 99.5% identity (99.6% similar) in 1566 aa overlap (41-1606:1-1559) 20 30 40 50 60 70 pF1KSD PPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAA ::::::::: :::::::::::::: NP_001 MNTPSQPRQ-------HFYPSRAQPPSSAA 10 20 80 90 100 110 120 130 pF1KSD SRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ 30 40 50 60 70 80 140 150 160 170 180 190 pF1KSD PGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIR 90 100 110 120 130 140 200 210 220 230 240 250 pF1KSD DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 150 160 170 180 190 200 260 270 280 290 300 310 pF1KSD RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPI 210 220 230 240 250 260 320 330 340 350 360 370 pF1KSD SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNG 270 280 290 300 310 320 380 390 400 410 420 430 pF1KSD MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEE 330 340 350 360 370 380 440 450 460 470 480 490 pF1KSD QAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL 390 400 410 420 430 440 500 510 520 530 540 550 pF1KSD LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPE 450 460 470 480 490 500 560 570 580 590 600 610 pF1KSD VENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKP 510 520 530 540 550 560 620 630 640 650 660 670 pF1KSD LNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCG 570 580 590 600 610 620 680 690 700 710 720 730 pF1KSD PDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTE 630 640 650 660 670 680 740 750 760 770 780 790 pF1KSD DIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQV 690 700 710 720 730 740 800 810 820 830 840 850 pF1KSD TQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLL 750 760 770 780 790 800 860 870 880 890 900 910 pF1KSD LNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIG 810 820 830 840 850 860 920 930 940 950 960 970 pF1KSD ELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQME 870 880 890 900 910 920 980 990 1000 1010 1020 1030 pF1KSD KIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQL 930 940 950 960 970 980 1040 1050 1060 1070 1080 1090 pF1KSD MAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQ 990 1000 1010 1020 1030 1040 1100 1110 1120 1130 1140 1150 pF1KSD LFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQR 1050 1060 1070 1080 1090 1100 1160 1170 1180 1190 1200 1210 pF1KSD SSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEG 1110 1120 1130 1140 1150 1160 1220 1230 1240 1250 1260 1270 pF1KSD LRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAV 1170 1180 1190 1200 1210 1220 1280 1290 1300 1310 1320 1330 pF1KSD QCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEIL 1230 1240 1250 1260 1270 1280 1340 1350 1360 1370 1380 1390 pF1KSD ELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLL 1290 1300 1310 1320 1330 1340 1400 1410 1420 1430 1440 1450 pF1KSD CKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEEL 1350 1360 1370 1380 1390 1400 1460 1470 1480 1490 1500 1510 pF1KSD NRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAV 1410 1420 1430 1440 1450 1460 1520 1530 1540 1550 1560 1570 pF1KSD LKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSW 1470 1480 1490 1500 1510 1520 1580 1590 1600 pF1KSD ESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::: NP_001 ESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1530 1540 1550 >>NP_937887 (OMIM: 600495,614251) eukaryotic translation (1512 aa) initn: 10017 init1: 10017 opt: 10017 Z-score: 4134.2 bits: 777.8 E(85289): 0 Smith-Waterman score: 10017; 99.9% identity (100.0% similar) in 1512 aa overlap (95-1606:1-1512) 70 80 90 100 110 120 pF1KSD PPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPT :::::::::::::::::::::::::::::: NP_937 MMIPSQISYPASQGAYYIPGQGRSTYVVPT 10 20 30 130 140 150 160 170 180 pF1KSD QQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 40 50 60 70 80 90 190 200 210 220 230 240 pF1KSD KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ 100 110 120 130 140 150 250 260 270 280 290 300 pF1KSD GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 160 170 180 190 200 210 310 320 330 340 350 360 pF1KSD EESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVE 220 230 240 250 260 270 370 380 390 400 410 420 pF1KSD IHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 IHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSP 280 290 300 310 320 330 430 440 450 460 470 480 pF1KSD VSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_937 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE 340 350 360 370 380 390 490 500 510 520 530 540 pF1KSD KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEA 400 410 420 430 440 450 550 560 570 580 590 600 pF1KSD NPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 NPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYK 460 470 480 490 500 510 610 620 630 640 650 660 pF1KSD SDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRL 520 530 540 550 560 570 670 680 690 700 710 720 pF1KSD QGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIA 580 590 600 610 620 630 730 740 750 760 770 780 pF1KSD TVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQ 640 650 660 670 680 690 790 800 810 820 830 840 pF1KSD QLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTV 700 710 720 730 740 750 850 860 870 880 890 900 pF1KSD NFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 NFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLG 760 770 780 790 800 810 910 920 930 940 950 960 pF1KSD NIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 NIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQ 820 830 840 850 860 870 970 980 990 1000 1010 1020 pF1KSD YFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 YFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREH 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KSD IKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 IKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGS 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KSD IDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 IDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDN 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KSD RRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRER 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KSD PSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLN 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KSD DMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 DMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQ 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KSD GLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLL 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KSD EILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRA 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KSD LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPL 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KSD RVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKE 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 pF1KSD DAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::::::::: NP_937 DAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1480 1490 1500 1510 >>NP_937885 (OMIM: 600495,614251) eukaryotic translation (1435 aa) initn: 9476 init1: 9476 opt: 9476 Z-score: 3912.3 bits: 736.6 E(85289): 3.5e-211 Smith-Waterman score: 9476; 99.9% identity (100.0% similar) in 1435 aa overlap (172-1606:1-1435) 150 160 170 180 190 200 pF1KSD PTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITE :::::::::::::::::::::::::::::: NP_937 MNQPPQIAPKRERKTIRIRDPNQGGKDITE 10 20 30 210 220 230 240 250 260 pF1KSD EIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 40 50 60 70 80 90 270 280 290 300 310 320 pF1KSD SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASVAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_937 ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 220 230 240 250 260 270 450 460 470 480 490 500 pF1KSD PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPAN 280 290 300 310 320 330 510 520 530 540 550 560 pF1KSD LSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNP 340 350 360 370 380 390 570 580 590 600 610 620 pF1KSD GPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDR 400 410 420 430 440 450 630 640 650 660 670 680 pF1KSD EFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLG 460 470 480 490 500 510 690 700 710 720 730 740 pF1KSD RTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAW 520 530 540 550 560 570 750 760 770 780 790 800 pF1KSD KPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERL 580 590 600 610 620 630 810 820 830 840 850 860 pF1KSD KGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKD 640 650 660 670 680 690 870 880 890 900 910 920 pF1KSD KDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEA 700 710 720 730 740 750 930 940 950 960 970 980 pF1KSD IMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 IMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSR 760 770 780 790 800 810 990 1000 1010 1020 1030 1040 pF1KSD IRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 IRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGG 820 830 840 850 860 870 1050 1060 1070 1080 1090 1100 pF1KSD PPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWG 880 890 900 910 920 930 1110 1120 1130 1140 1150 1160 pF1KSD KGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKA 940 950 960 970 980 990 1170 1180 1190 1200 1210 1220 pF1KSD GDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDR 1000 1010 1020 1030 1040 1050 1230 1240 1250 1260 1270 1280 pF1KSD DRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 DRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSL 1060 1070 1080 1090 1100 1110 1290 1300 1310 1320 1330 1340 pF1KSD LFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIP 1120 1130 1140 1150 1160 1170 1350 1360 1370 1380 1390 1400 pF1KSD HVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 HVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGT 1180 1190 1200 1210 1220 1230 1410 1420 1430 1440 1450 1460 pF1KSD LWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEG 1240 1250 1260 1270 1280 1290 1470 1480 1490 1500 1510 1520 pF1KSD SSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKY 1300 1310 1320 1330 1340 1350 1530 1540 1550 1560 1570 1580 pF1KSD LCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQG 1360 1370 1380 1390 1400 1410 1590 1600 pF1KSD KGVALKSVTAFFKWLREAEEESDHN ::::::::::::::::::::::::: NP_937 KGVALKSVTAFFKWLREAEEESDHN 1420 1430 >>NP_004944 (OMIM: 600495,614251) eukaryotic translation (1404 aa) initn: 9244 init1: 5898 opt: 9246 Z-score: 3817.9 bits: 719.1 E(85289): 6.4e-206 Smith-Waterman score: 9246; 99.9% identity (99.9% similar) in 1404 aa overlap (204-1606:1-1404) 180 190 200 210 220 230 pF1KSD QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV :::::::::::::::::::::::::::::: NP_004 MSGARTASTPTPPQTGGGLEPQANGETPQV 10 20 30 240 250 260 270 280 290 pF1KSD AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KSD GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQ 100 110 120 130 140 150 360 370 380 390 400 410 pF1KSD APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNG 160 170 180 190 200 210 420 430 440 450 460 470 pF1KSD APSPPAVDLSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: NP_004 APSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG 220 230 240 250 260 270 480 490 500 510 520 530 pF1KSD EAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEA 280 290 300 310 320 330 540 550 560 570 580 590 pF1KSD VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAEN 340 350 360 370 380 390 600 610 620 630 640 650 pF1KSD IQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANK 400 410 420 430 440 450 660 670 680 690 700 710 pF1KSD TPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGP-AGLGPRRSQ :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_004 TPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPQAGLGPRRSQ 460 470 480 490 500 510 720 730 740 750 760 770 pF1KSD QGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVR 520 530 540 550 560 570 780 790 800 810 820 830 pF1KSD SILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 580 590 600 610 620 630 840 850 860 870 880 890 pF1KSD KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 640 650 660 670 680 690 900 910 920 930 940 950 pF1KSD EARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKD 700 710 720 730 740 750 960 970 980 990 1000 1010 pF1KSD LDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQI 760 770 780 790 800 810 1020 1030 1040 1050 1060 1070 pF1KSD HKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPID 820 830 840 850 860 870 1080 1090 1100 1110 1120 1130 pF1KSD TSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSA 880 890 900 910 920 930 1140 1150 1160 1170 1180 1190 pF1KSD LQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRS 940 950 960 970 980 990 1200 1210 1220 1230 1240 1250 pF1KSD FSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKK 1000 1010 1020 1030 1040 1050 1260 1270 1280 1290 1300 1310 pF1KSD SKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLL 1060 1070 1080 1090 1100 1110 1320 1330 1340 1350 1360 1370 pF1KSD CAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKP 1120 1130 1140 1150 1160 1170 1380 1390 1400 1410 1420 1430 pF1KSD LRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYT 1180 1190 1200 1210 1220 1230 1440 1450 1460 1470 1480 1490 pF1KSD LGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTA 1240 1250 1260 1270 1280 1290 1500 1510 1520 1530 1540 1550 pF1KSD VCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMF 1300 1310 1320 1330 1340 1350 1560 1570 1580 1590 1600 pF1KSD FDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1360 1370 1380 1390 1400 >>XP_016858183 (OMIM: 603929) PREDICTED: eukaryotic tran (1603 aa) initn: 3575 init1: 1516 opt: 2340 Z-score: 979.9 bits: 194.2 E(85289): 7.6e-48 Smith-Waterman score: 4435; 49.1% identity (68.2% similar) in 1693 aa overlap (34-1606:3-1603) 10 20 30 40 50 60 pF1KSD APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQ--MNTPSQPR-QGGFRSLQHFYP : ::. . : :. ::::: .: : XP_016 MNSQPQTRSPFAAGPRPPHHQGGFRPIQFFQR 10 20 30 70 80 90 100 110 pF1KSD SRAQPPSSAASRVQSAAPA-RPG---PAAHVYPAGSQVMMIPS-QISYPASQGAYYIPGQ . ::: .. . ...:. ::: :.: :: :....::. . ::. :: : : XP_016 PQIQPPRAT---IPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMPYPVPQGPQYCIPQ 40 50 60 70 80 120 130 140 150 160 170 pF1KSD GRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQGVQQFPTGVAPAPV : . :: : ::::::: .:: :::: .: .: ..:. .::.: : : ..:. XP_016 YRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPT-- 90 100 110 120 130 140 180 190 200 210 220 pF1KSD LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA----------RTASTPTPPQTGG ..::: :::.::::::::::::::::::::::. : .::::::: XP_016 -QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQ--- 150 160 170 180 190 200 230 240 250 260 270 pF1KSD GLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP---SPSP : ...:. . .: .: . . :. : . . ..: .:.: : :::: XP_016 ----QLPSQVPEHSPVVYGTVES-AHLAASTPVTAASD----QKQEEKPKPDPVLKSPSP 210 220 230 240 250 280 290 300 310 pF1KSD VL-----------EPGSEPNLAVLSI---PGDTMTTIQMSVEEST---PISRE-TGEPYR :: : . . :..:: : : :: .:: : : ...: XP_016 VLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIF 260 270 280 290 300 310 320 330 340 350 360 pF1KSD L----------SPEPTPLAEPILEVEVTLSKPVPESE----FSSSPLQ-APT--PLASHT ::. . : : . : :.: .: . ..: . ::. ::.: : XP_016 TTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSST 320 330 340 350 360 370 370 380 390 400 410 420 pF1KSD VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL-LNGAPSPPAVD :.: ::. :: : .:: :.. . : . : . :::. :. :.: XP_016 NLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENP-PEEMKLECIPAP---- 380 390 400 410 420 430 440 450 460 470 pF1KSD LSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQ----EEEMEEEEE------EE ..: . : : ..:: : .::.: ...::. .. .::.: :. XP_016 ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSED 430 440 450 460 470 480 480 490 500 510 520 pF1KSD EGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVSVPKRRRKIK : . :.:.. ::.: .. .:.:: :.:..::: .: : XP_016 AKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAITVPKTWKKPK 490 500 510 520 530 530 540 550 560 570 580 pF1KSD ELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPRPEEADETWD . .. .: . :. : . .. .: .. . : :: . : . . . ..:. . XP_016 DRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-KVKAVEENGE 540 550 560 570 580 590 590 600 610 620 pF1KSD SKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKRYDREFLLGF : ..::... :: . .: ..::: . : ::.::::::: : XP_016 EAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDF 600 610 620 630 640 650 630 640 650 660 670 680 pF1KSD QFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPSFANLGRTTL ::. : .::::::: :::::::: : : :.: ::: : ::::::.::..:: : XP_016 QFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPAFADFGRQT- 660 670 680 690 700 690 700 710 720 730 740 pF1KSD STRGPPRGGPGGELPRG-PA-GLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP ::: :: : ..: :::: : :.:::::: :: . ::..:.:::.:::: XP_016 ---------PGG---RGVPLLNVGSRRSQPGQRREPRKII-TVSVKEDVHLKKAENAWKP 710 720 730 740 750 750 760 770 780 790 800 pF1KSD SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG :.:: : .: .. :::.:::.:::::::::::::.::::::. :..:::::::: XP_016 SQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKG 760 770 780 790 800 810 820 830 840 850 860 pF1KSD VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD ::::.:::::.::.::::::::::::..:::: ..:: :::::::::::::::::::: XP_016 VIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKA 810 820 830 840 850 860 870 880 890 900 910 920 pF1KSD DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM ::.::::::::.. :.. ::: ::..:::::.: :::::.:::::::::::::::::::: XP_016 DDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIM 870 880 890 900 910 920 930 940 950 960 970 980 pF1KSD HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR :::::::::::::::::::::::::::::::::::::::::::::::::.::.::::::: XP_016 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIR 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 pF1KSD FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP ::::::.::: ::: ::.:::::::.::::::..::..:. ::::::.: .::: : XP_016 FMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--EKRR---P 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRL-SWGK : ..: ::.:::::: .:.:: .: :.. ::::: .:: . :: .: ..: :::: XP_016 G--VQR----VDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQL-VPKAQLGSWGK 1050 1060 1070 1080 1090 1110 1120 1130 1140 1150 pF1KSD GSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRRVV-QRSSLS :::::. :. .:: : ..:.:::::::: .:. :: :.::.. .:.:.. XP_016 GSSGGAKASETDA----LRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMG 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 pF1KSD RERGEKAGDRGD-RLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRK ::...: . : . :::. : :: .. ::. :: . : XP_016 REKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLETVKQLTG 1160 1170 1180 1190 1200 1220 1230 1240 1250 1260 pF1KSD AASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHLNDMKEA .... .. ... ::.: : .: . ::::::::::.:::.::.:.::.::.::: XP_016 GVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEA 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD VQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEI .:::.:: . .:: .::: ::::::::: :.:.::::::.::. . .:: ....:. : XP_016 MQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSET 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGL ::::.:: :::::.::::::::::.:.:::. : :: :..::: :.:.:. :: ::: : XP_016 LELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEE---SEAPGQRALP :::.:. ::::.::::: ::::.:::::.:. :. :::... .. ::: ... : XP_016 LCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETP-L .::: ..::::. : ..: ...:::.::::.: :. : :..:::::::: .::: .. . XP_016 AEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD RVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVK :::.::.: :. .: ::: : .::::::::::: .: :.:: :::::::: ::::.:.. XP_016 RVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVIS 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 pF1KSD EDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::.::::::::::.::::::::::::: :::::::::. : XP_016 EDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1570 1580 1590 1600 >>XP_016858184 (OMIM: 603929) PREDICTED: eukaryotic tran (1602 aa) initn: 3575 init1: 1516 opt: 2331 Z-score: 976.2 bits: 193.5 E(85289): 1.2e-47 Smith-Waterman score: 4444; 49.2% identity (68.5% similar) in 1686 aa overlap (34-1606:3-1602) 10 20 30 40 50 60 pF1KSD APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQ--MNTPSQPR-QGGFRSLQHFYP : ::. . : :. ::::: .: : XP_016 MNSQPQTRSPFAAGPRPPHHQGGFRPIQFFQR 10 20 30 70 80 90 100 110 pF1KSD SRAQPPSSAASRVQSAAPA-RPG---PAAHVYPAGSQVMMIPS-QISYPASQGAYYIPGQ . ::: .. . ...:. ::: :.: :: :....::. . ::. :: : : XP_016 PQIQPPRAT---IPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMPYPVPQGPQYCIPQ 40 50 60 70 80 120 130 140 150 160 170 pF1KSD GRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQGVQQFPTGVAPAPV : . :: : ::::::: .:: :::: .: .: ..:. .::.: : : ..:. XP_016 YRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPT-- 90 100 110 120 130 140 180 190 200 210 220 pF1KSD LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPP---QTGGGLEPQAN ..::: :::.::::::::::::::::::::::. . .:::: :. :: XP_016 -QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGG-GSRNPTPPIGRPTSTPTPPQLP 150 160 170 180 190 200 230 240 250 260 270 pF1KSD GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP---SPSPVL----- ...:. . .: .: . . :. : . . ..: .:.: : :::::: XP_016 SQVPEHSPVVYGTVES-AHLAASTPVTAASD----QKQEEKPKPDPVLKSPSPVLRLVLS 210 220 230 240 250 280 290 300 310 320 pF1KSD ------EPGSEPNLAVLSI---PGDTMTTIQMSVEEST---PISRE-TGEPYRL------ : . . :..:: : : :: .:: : : ...: XP_016 GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR 260 270 280 290 300 310 330 340 350 360 pF1KSD ----SPEPTPLAEPILEVEVTLSKPVPESE----FSSSPLQ-APT--PLASHTVEIHEPN ::. . : : . : :.: .: . ..: . ::. ::.: : :.: : XP_016 CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN 320 330 340 350 360 370 370 380 390 400 410 420 pF1KSD GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL-LNGAPSPPAVDLSPVSEP :. :: : .:: :.. . : . : . :::. :. :.: ..: . : XP_016 GV--SEKLSA-TESIVEIVKQEVLPLTLELEILENP-PEEMKLECIPAP----ITPSTVP 380 390 400 410 420 430 440 450 460 470 pF1KSD EEQAKEVTASVAPPTIPSATPATAPSATSPAQ----EEEMEEEEE------EEEGEAGEA : ..:: : .::.: ...::. .. .::.: :. : . XP_016 SFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD GEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNK--K :.:.. ::.: .. .:.:: :.:..::: .: :. .. . XP_016 IEVEADGQTEEILDSQNLNSRRSPVPA------------QIAITVPKTWKKPKDRTRTTE 490 500 510 520 530 540 550 560 570 580 pF1KSD EAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPRPEEADETWDSKEDKIH : . :. : . .. .: .. . : :: . : . . . ..:. . : . XP_016 EMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-KVKAVEENGEEAEPVRN 540 550 560 570 580 590 590 600 610 620 630 pF1KSD NAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM .::... :: . .: ..::: . : ::.::::::: :::. : . XP_016 GAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACI 600 610 620 630 640 650 640 650 660 670 680 690 pF1KSD QKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPR ::::::: :::::::: : : :.: ::: : ::::::.::..:: : XP_016 QKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPAFADFGRQT-------- 660 670 680 690 700 700 710 720 730 740 750 pF1KSD GGPGGELPRG-PA-GLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAA ::: :: : ..: :::: : :.:::::: :: . ::..:.:::.:::::.:: XP_016 --PGG---RGVPLLNVGSRRSQPGQRREPRKII-TVSVKEDVHLKKAENAWKPSQKR--- 710 720 730 740 750 760 770 780 790 800 810 pF1KSD DKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFE : .: .. :::.:::.:::::::::::::.::::::. :..::::::::::::.:: XP_016 --DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFE 760 770 780 790 800 810 820 830 840 850 860 870 pF1KSD KAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEK :::.::.::::::::::::..:::: ..:: :::::::::::::::::::: ::.:::: XP_016 KAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEK 820 830 840 850 860 870 880 890 900 910 920 930 pF1KSD KQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKL ::::.. :.. ::: ::..:::::.: :::::.::::::::::::::::::::::::::: XP_016 KQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKL 880 890 900 910 920 930 940 950 960 970 980 990 pF1KSD LKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVL ::::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::. XP_016 LKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVI 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD DLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRG ::: ::: ::.:::::::.::::::..::..:. ::::::.: .::: :: ..: XP_016 DLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--EKRR---PG--VQR- 1000 1010 1020 1030 1040 1060 1070 1080 1090 1100 pF1KSD LPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRL-SWGKGSSGGSG ::.:::::: .:.:: .: :.. ::::: .:: . :: .: ..: :::::::::. XP_016 ---VDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQL-VPKAQLGSWGKGSSGGAK 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 pF1KSD AKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRRVV-QRSSLSRERGEKA :. .:: : ..:.:::::::: .:. :: :.::.. .:.:..::...: XP_016 ASETDA----LRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKP 1110 1120 1130 1140 1150 1170 1180 1190 1200 1210 1220 pF1KSD GDRGD-RLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTED . : . :::. : :: .. ::. :: . : .... .. XP_016 LPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLETVKQLTGGVDVERN 1160 1170 1180 1190 1200 1230 1240 1250 1260 1270 pF1KSD RDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQEL ... ::.: : .: . ::::::::::.:::.::.:.::.::.:::.:::.:: XP_016 STEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEEL 1210 1220 1230 1240 1250 1260 1280 1290 1300 1310 1320 1330 pF1KSD ASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDM . .:: .::: ::::::::: :.:.::::::.::. . .:: ....:. : ::::.:: XP_016 NAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDM 1270 1280 1290 1300 1310 1320 1340 1350 1360 1370 1380 1390 pF1KSD EIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGP :::::.::::::::::.:.:::. : :: :..::: :.:.:. :: ::: ::::.:. XP_016 AIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSH 1330 1340 1350 1360 1370 1380 1400 1410 1420 1430 1440 1450 pF1KSD KKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEE---SEAPGQRALPSEELNRQ ::::.::::: ::::.:::::.:. :. :::... .. ::: ... : .::: .. XP_016 KKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKR 1390 1400 1410 1420 1430 1440 1460 1470 1480 1490 1500 1510 pF1KSD LEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETP-LRVDVAVL ::::. : ..: ...:::.::::.: :. : :..:::::::: .::: .. .:::.::. XP_016 LEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVI 1450 1460 1470 1480 1490 1500 1520 1530 1540 1550 1560 1570 pF1KSD KARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSW : :. .: ::: : .::::::::::: .: :.:: :::::::: ::::.:..:::::.: XP_016 KQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKW 1510 1520 1530 1540 1550 1560 1580 1590 1600 pF1KSD ESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN :::::::::.::::::::::::: :::::::::. : XP_016 ESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1570 1580 1590 1600 1606 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:12:02 2016 done: Thu Nov 3 08:12:05 2016 Total Scan time: 18.900 Total Display time: 1.030 Function used was FASTA [36.3.4 Apr, 2011]