FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0032, 479 aa 1>>>pF1KSDB0032 479 - 479 aa - 479 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8222+/-0.000324; mu= 11.4081+/- 0.020 mean_var=109.3659+/-22.760, 0's: 0 Z-trim(118.6): 76 B-trim: 1668 in 1/52 Lambda= 0.122640 statistics sampled from 31595 (31692) to 31595 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.372), width: 16 Scan time: 10.710 The best scores are: opt bits E(85289) NP_055208 (OMIM: 605920) double-stranded RNA-bindi ( 479) 3155 568.8 1.1e-161 NP_001157856 (OMIM: 605920) double-stranded RNA-bi ( 479) 3155 568.8 1.1e-161 NP_001157853 (OMIM: 605920) double-stranded RNA-bi ( 538) 3150 568.0 2.3e-161 NP_001157857 (OMIM: 605920) double-stranded RNA-bi ( 473) 3117 562.1 1.2e-159 NP_001157852 (OMIM: 605920) double-stranded RNA-bi ( 570) 3115 561.8 1.8e-159 NP_001157854 (OMIM: 605920) double-stranded RNA-bi ( 504) 2697 487.8 3e-137 NP_001157855 (OMIM: 605920) double-stranded RNA-bi ( 398) 2203 400.3 5e-111 NP_059347 (OMIM: 601716) double-stranded RNA-bindi ( 577) 1203 223.5 1.2e-57 NP_001309858 (OMIM: 601716) double-stranded RNA-bi ( 577) 1203 223.5 1.2e-57 NP_001309859 (OMIM: 601716) double-stranded RNA-bi ( 577) 1203 223.5 1.2e-57 NP_001306064 (OMIM: 601716) double-stranded RNA-bi ( 577) 1203 223.5 1.2e-57 XP_016883517 (OMIM: 601716) PREDICTED: double-stra ( 536) 1187 220.6 8.3e-57 NP_001309860 (OMIM: 601716) double-stranded RNA-bi ( 536) 1187 220.6 8.3e-57 NP_001309861 (OMIM: 601716) double-stranded RNA-bi ( 583) 1181 219.6 1.9e-56 NP_001309862 (OMIM: 601716) double-stranded RNA-bi ( 583) 1181 219.6 1.9e-56 XP_006723928 (OMIM: 601716) PREDICTED: double-stra ( 583) 1181 219.6 1.9e-56 NP_001309857 (OMIM: 601716) double-stranded RNA-bi ( 542) 1165 216.8 1.2e-55 XP_011527317 (OMIM: 601716) PREDICTED: double-stra ( 542) 1165 216.8 1.2e-55 NP_004593 (OMIM: 601716) double-stranded RNA-bindi ( 496) 1130 210.5 8.5e-54 NP_059346 (OMIM: 601716) double-stranded RNA-bindi ( 496) 1130 210.5 8.5e-54 NP_059348 (OMIM: 601716) double-stranded RNA-bindi ( 496) 1130 210.5 8.5e-54 NP_001032405 (OMIM: 601716) double-stranded RNA-bi ( 502) 1108 206.7 1.3e-52 NP_001306063 (OMIM: 601716) double-stranded RNA-bi ( 502) 1108 206.7 1.3e-52 XP_005260584 (OMIM: 601716) PREDICTED: double-stra ( 502) 1108 206.7 1.3e-52 NP_001309856 (OMIM: 601716) double-stranded RNA-bi ( 502) 1108 206.7 1.3e-52 NP_001132990 (OMIM: 603424,612067) interferon-indu ( 288) 254 55.4 2.4e-07 NP_001132989 (OMIM: 603424,612067) interferon-indu ( 302) 254 55.4 2.5e-07 NP_003681 (OMIM: 603424,612067) interferon-inducib ( 313) 254 55.4 2.6e-07 >>NP_055208 (OMIM: 605920) double-stranded RNA-binding p (479 aa) initn: 3155 init1: 3155 opt: 3155 Z-score: 3023.4 bits: 568.8 E(85289): 1.1e-161 Smith-Waterman score: 3155; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 370 380 390 400 410 420 430 440 450 460 470 pF1KSD SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV 430 440 450 460 470 >>NP_001157856 (OMIM: 605920) double-stranded RNA-bindin (479 aa) initn: 3155 init1: 3155 opt: 3155 Z-score: 3023.4 bits: 568.8 E(85289): 1.1e-161 Smith-Waterman score: 3155; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 370 380 390 400 410 420 430 440 450 460 470 pF1KSD SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV 430 440 450 460 470 >>NP_001157853 (OMIM: 605920) double-stranded RNA-bindin (538 aa) initn: 3150 init1: 3150 opt: 3150 Z-score: 3017.9 bits: 568.0 E(85289): 2.3e-161 Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 370 380 390 400 410 420 430 440 450 460 470 pF1KSD SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQAA 430 440 450 460 470 480 NP_001 LSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCKKSNSAV 490 500 510 520 530 >>NP_001157857 (OMIM: 605920) double-stranded RNA-bindin (473 aa) initn: 3117 init1: 3117 opt: 3117 Z-score: 2987.2 bits: 562.1 E(85289): 1.2e-159 Smith-Waterman score: 3117; 100.0% identity (100.0% similar) in 473 aa overlap (7-479:1-473) 10 20 30 40 50 60 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG 10 20 30 40 50 70 80 90 100 110 120 pF1KSD SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSER 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFF 360 370 380 390 400 410 430 440 450 460 470 pF1KSD SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV 420 430 440 450 460 470 >>NP_001157852 (OMIM: 605920) double-stranded RNA-bindin (570 aa) initn: 3115 init1: 3115 opt: 3115 Z-score: 2984.0 bits: 561.8 E(85289): 1.8e-159 Smith-Waterman score: 3115; 99.6% identity (100.0% similar) in 474 aa overlap (5-478:37-510) 10 20 30 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVA ..:::::::::::::::::::::::::::: NP_001 KTAMCLVNELARFNRVQPQYKLLNERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD NKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRA 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD NYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD RSPQNGESGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSPQNGESGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD EFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGM 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD NPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD EAMLLQLGYKASTNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAMLLQLGYKASTNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEAS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD RHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSS 430 440 450 460 470 480 460 470 pF1KSD PTPPCSPVQPSKQLEYLARIQGFQV :::::::::::::::::::::::: NP_001 PTPPCSPVQPSKQLEYLARIQGFQAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLR 490 500 510 520 530 540 >>NP_001157854 (OMIM: 605920) double-stranded RNA-bindin (504 aa) initn: 2697 init1: 2697 opt: 2697 Z-score: 2585.1 bits: 487.8 E(85289): 3e-137 Smith-Waterman score: 2697; 100.0% identity (100.0% similar) in 407 aa overlap (73-479:1-407) 50 60 70 80 90 100 pF1KSD LPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMY :::::::::::::::::::::::::::::: NP_001 MKRGEPAIYRPLDPKPFPNYRANYNFRGMY 10 20 30 110 120 130 140 150 160 pF1KSD NQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGES 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD GKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD NSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQ 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLG 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD YKASTNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKASTNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGT 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD TLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPV 340 350 360 370 380 390 470 pF1KSD QPSKQLEYLARIQGFQV ::::::::::::::::: NP_001 QPSKQLEYLARIQGFQVHYCDRQSGKECVTCLTLAPVQMTFHAIGSSIEASHDQAALSAL 400 410 420 430 440 450 >>NP_001157855 (OMIM: 605920) double-stranded RNA-bindin (398 aa) initn: 2203 init1: 2203 opt: 2203 Z-score: 2114.3 bits: 400.3 E(85289): 5e-111 Smith-Waterman score: 2203; 100.0% identity (100.0% similar) in 338 aa overlap (141-478:1-338) 120 130 140 150 160 170 pF1KSD PKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDK :::::::::::::::::::::::::::::: NP_001 MKALQALQNEPIPERSPQNGESGKDVDDDK 10 20 30 180 190 200 210 220 230 pF1KSD DANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKK 40 50 60 70 80 90 240 250 260 270 280 290 pF1KSD RAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEK 100 110 120 130 140 150 300 310 320 330 340 350 pF1KSD EPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQ 160 170 180 190 200 210 360 370 380 390 400 410 pF1KSD DQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPK 220 230 240 250 260 270 420 430 440 450 460 470 pF1KSD DMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMNQPSSSFFSISPTSNSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEY 280 290 300 310 320 330 pF1KSD LARIQGFQV :::::::: NP_001 LARIQGFQAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQD 340 350 360 370 380 390 >>NP_059347 (OMIM: 601716) double-stranded RNA-binding p (577 aa) initn: 664 init1: 530 opt: 1203 Z-score: 1155.7 bits: 223.5 E(85289): 1.2e-57 Smith-Waterman score: 1349; 49.3% identity (72.9% similar) in 513 aa overlap (7-479:1-504) 10 20 30 40 50 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKAL-----TESTLP-----KPVQKP : .::... . . ::.: . .:.. .. : : :.:: .:.:. NP_059 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNS 10 20 30 40 50 60 70 80 90 100 pF1KSD --PKSNVNNNPG---SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQ :....... . :::::::::.: :: :. .:.:.:: . :::.:: : NP_059 ALPSASITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD RYH--CPVPKIFY-VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGE :: ::: ..: :.:.::...: :.:::::::.:.:: :::. :::::.::: ::. NP_059 RYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD SGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGE . .... :::::: :::::::::.::.::: .::::::::.:::.:::::: .::: NP_059 ES----EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGE 180 190 200 210 220 230 230 240 250 260 270 pF1KSD GNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISR :.:::.::: :: .::.:::::::::.::. : .::. : ::: ..::::::.::::: NP_059 GKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISR 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD LAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLL :::::::::::::.:.::.:::.::::::::::::::..: ::: :::.::.:::: :: NP_059 LAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE 300 310 320 330 340 350 340 350 360 370 380 390 pF1KSD QLGYKA------STNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEA ::.:. . :... ::: .: .: : : :: .. .: . . : .. NP_059 ILGFKVPQAQPTKPALKSE-EKTPIKKPGDGRKVTFFEPGSGDENGTSN-KEDEFRMPYL 360 370 380 390 400 400 410 420 430 440 pF1KSD SRHKVISGTTLGYLSPK-------DMNQPSSSFFSISPT---SNSSATIARELLMNGTSS :.... .: . . :. .... ...: .:. .. .: ::::::..::: NP_059 SHQQLPAG--ILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSP 410 420 430 440 450 460 450 460 470 pF1KSD TAEAIGLKG--SSPTPPCSPV-QPSKQLEYLARIQGFQV :::.: ::. :: : .:. .::.::.::.:.::::: NP_059 TAETI-LKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSS 470 480 490 500 510 520 NP_059 QPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC 530 540 550 560 570 >>NP_001309858 (OMIM: 601716) double-stranded RNA-bindin (577 aa) initn: 664 init1: 530 opt: 1203 Z-score: 1155.7 bits: 223.5 E(85289): 1.2e-57 Smith-Waterman score: 1349; 49.3% identity (72.9% similar) in 513 aa overlap (7-479:1-504) 10 20 30 40 50 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKAL-----TESTLP-----KPVQKP : .::... . . ::.: . .:.. .. : : :.:: .:.:. NP_001 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNS 10 20 30 40 50 60 70 80 90 100 pF1KSD --PKSNVNNNPG---SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQ :....... . :::::::::.: :: :. .:.:.:: . :::.:: : NP_001 ALPSASITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD RYH--CPVPKIFY-VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGE :: ::: ..: :.:.::...: :.:::::::.:.:: :::. :::::.::: ::. NP_001 RYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD SGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGE . .... :::::: :::::::::.::.::: .::::::::.:::.:::::: .::: NP_001 ES----EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGE 180 190 200 210 220 230 230 240 250 260 270 pF1KSD GNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISR :.:::.::: :: .::.:::::::::.::. : .::. : ::: ..::::::.::::: NP_001 GKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISR 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD LAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLL :::::::::::::.:.::.:::.::::::::::::::..: ::: :::.::.:::: :: NP_001 LAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE 300 310 320 330 340 350 340 350 360 370 380 390 pF1KSD QLGYKA------STNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEA ::.:. . :... ::: .: .: : : :: .. .: . . : .. NP_001 ILGFKVPQAQPTKPALKSE-EKTPIKKPGDGRKVTFFEPGSGDENGTSN-KEDEFRMPYL 360 370 380 390 400 400 410 420 430 440 pF1KSD SRHKVISGTTLGYLSPK-------DMNQPSSSFFSISPT---SNSSATIARELLMNGTSS :.... .: . . :. .... ...: .:. .. .: ::::::..::: NP_001 SHQQLPAG--ILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSP 410 420 430 440 450 460 450 460 470 pF1KSD TAEAIGLKG--SSPTPPCSPV-QPSKQLEYLARIQGFQV :::.: ::. :: : .:. .::.::.::.:.::::: NP_001 TAETI-LKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSS 470 480 490 500 510 520 NP_001 QPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC 530 540 550 560 570 >>NP_001309859 (OMIM: 601716) double-stranded RNA-bindin (577 aa) initn: 664 init1: 530 opt: 1203 Z-score: 1155.7 bits: 223.5 E(85289): 1.2e-57 Smith-Waterman score: 1349; 49.3% identity (72.9% similar) in 513 aa overlap (7-479:1-504) 10 20 30 40 50 pF1KSD MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKAL-----TESTLP-----KPVQKP : .::... . . ::.: . .:.. .. : : :.:: .:.:. NP_001 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNS 10 20 30 40 50 60 70 80 90 100 pF1KSD --PKSNVNNNPG---SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQ :....... . :::::::::.: :: :. .:.:.:: . :::.:: : NP_001 ALPSASITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD RYH--CPVPKIFY-VQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGE :: ::: ..: :.:.::...: :.:::::::.:.:: :::. :::::.::: ::. NP_001 RYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD SGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGE . .... :::::: :::::::::.::.::: .::::::::.:::.:::::: .::: NP_001 ES----EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGE 180 190 200 210 220 230 230 240 250 260 270 pF1KSD GNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISR :.:::.::: :: .::.:::::::::.::. : .::. : ::: ..::::::.::::: NP_001 GKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISR 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD LAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLL :::::::::::::.:.::.:::.::::::::::::::..: ::: :::.::.:::: :: NP_001 LAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE 300 310 320 330 340 350 340 350 360 370 380 390 pF1KSD QLGYKA------STNLQDQLEKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEA ::.:. . :... ::: .: .: : : :: .. .: . . : .. NP_001 ILGFKVPQAQPTKPALKSE-EKTPIKKPGDGRKVTFFEPGSGDENGTSN-KEDEFRMPYL 360 370 380 390 400 400 410 420 430 440 pF1KSD SRHKVISGTTLGYLSPK-------DMNQPSSSFFSISPT---SNSSATIARELLMNGTSS :.... .: . . :. .... ...: .:. .. .: ::::::..::: NP_001 SHQQLPAG--ILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSP 410 420 430 440 450 460 450 460 470 pF1KSD TAEAIGLKG--SSPTPPCSPV-QPSKQLEYLARIQGFQV :::.: ::. :: : .:. .::.::.::.:.::::: NP_001 TAETI-LKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSS 470 480 490 500 510 520 NP_001 QPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC 530 540 550 560 570 479 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:12:44 2016 done: Thu Nov 3 08:12:45 2016 Total Scan time: 10.710 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]