FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0035, 469 aa 1>>>pF1KSDB0035 469 - 469 aa - 469 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7499+/-0.000396; mu= -16.4385+/- 0.025 mean_var=385.0934+/-77.032, 0's: 0 Z-trim(123.5): 4 B-trim: 0 in 0/58 Lambda= 0.065357 statistics sampled from 43439 (43443) to 43439 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.509), width: 16 Scan time: 12.190 The best scores are: opt bits E(85289) XP_011536857 (OMIM: 616381) PREDICTED: zinc finger ( 608) 3170 312.7 1.8e-84 XP_016875095 (OMIM: 616381) PREDICTED: zinc finger ( 616) 3170 312.7 1.9e-84 NP_060082 (OMIM: 616381) zinc finger CCHC domain-c ( 707) 3170 312.7 2.1e-84 XP_006719554 (OMIM: 616381) PREDICTED: zinc finger ( 630) 3120 308.0 5e-83 >>XP_011536857 (OMIM: 616381) PREDICTED: zinc finger CCH (608 aa) initn: 3170 init1: 3170 opt: 3170 Z-score: 1637.4 bits: 312.7 E(85289): 1.8e-84 Smith-Waterman score: 3170; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:140-608) 10 20 30 pF1KSD MKDCPMPRNAARISEKRKEYMDACGEANNQ :::::::::::::::::::::::::::::: XP_011 HIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMKDCPMPRNAARISEKRKEYMDACGEANNQ 110 120 130 140 150 160 40 50 60 70 80 90 pF1KSD NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL 170 180 190 200 210 220 100 110 120 130 140 150 pF1KSD ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI 230 240 250 260 270 280 160 170 180 190 200 210 pF1KSD PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS 290 300 310 320 330 340 220 230 240 250 260 270 pF1KSD DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG 350 360 370 380 390 400 280 290 300 310 320 330 pF1KSD AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP 410 420 430 440 450 460 340 350 360 370 380 390 pF1KSD EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS 470 480 490 500 510 520 400 410 420 430 440 450 pF1KSD VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI 530 540 550 560 570 580 460 pF1KSD RSLLKNSPRNQQKNKKASE ::::::::::::::::::: XP_011 RSLLKNSPRNQQKNKKASE 590 600 >>XP_016875095 (OMIM: 616381) PREDICTED: zinc finger CCH (616 aa) initn: 3170 init1: 3170 opt: 3170 Z-score: 1637.3 bits: 312.7 E(85289): 1.9e-84 Smith-Waterman score: 3170; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:148-616) 10 20 30 pF1KSD MKDCPMPRNAARISEKRKEYMDACGEANNQ :::::::::::::::::::::::::::::: XP_016 HIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMKDCPMPRNAARISEKRKEYMDACGEANNQ 120 130 140 150 160 170 40 50 60 70 80 90 pF1KSD NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL 180 190 200 210 220 230 100 110 120 130 140 150 pF1KSD ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI 240 250 260 270 280 290 160 170 180 190 200 210 pF1KSD PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS 300 310 320 330 340 350 220 230 240 250 260 270 pF1KSD DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG 360 370 380 390 400 410 280 290 300 310 320 330 pF1KSD AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP 420 430 440 450 460 470 340 350 360 370 380 390 pF1KSD EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS 480 490 500 510 520 530 400 410 420 430 440 450 pF1KSD VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI 540 550 560 570 580 590 460 pF1KSD RSLLKNSPRNQQKNKKASE ::::::::::::::::::: XP_016 RSLLKNSPRNQQKNKKASE 600 610 >>NP_060082 (OMIM: 616381) zinc finger CCHC domain-conta (707 aa) initn: 3170 init1: 3170 opt: 3170 Z-score: 1636.4 bits: 312.7 E(85289): 2.1e-84 Smith-Waterman score: 3170; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:239-707) 10 20 30 pF1KSD MKDCPMPRNAARISEKRKEYMDACGEANNQ :::::::::::::::::::::::::::::: NP_060 HIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMKDCPMPRNAARISEKRKEYMDACGEANNQ 210 220 230 240 250 260 40 50 60 70 80 90 pF1KSD NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL 270 280 290 300 310 320 100 110 120 130 140 150 pF1KSD ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSI 330 340 350 360 370 380 160 170 180 190 200 210 pF1KSD PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PMQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDS 390 400 410 420 430 440 220 230 240 250 260 270 pF1KSD DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DMEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASG 450 460 470 480 490 500 280 290 300 310 320 330 pF1KSD AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AVDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVP 510 520 530 540 550 560 340 350 360 370 380 390 pF1KSD EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EGKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGS 570 580 590 600 610 620 400 410 420 430 440 450 pF1KSD VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VVPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRI 630 640 650 660 670 680 460 pF1KSD RSLLKNSPRNQQKNKKASE ::::::::::::::::::: NP_060 RSLLKNSPRNQQKNKKASE 690 700 >>XP_006719554 (OMIM: 616381) PREDICTED: zinc finger CCH (630 aa) initn: 3119 init1: 3119 opt: 3120 Z-score: 1611.7 bits: 308.0 E(85289): 5e-83 Smith-Waterman score: 3120; 99.1% identity (99.4% similar) in 468 aa overlap (2-469:163-630) 10 20 30 pF1KSD MKDCPMPRNAARISEKRKEYMDACGEANNQN :. ::::::::::::::::::::::::: XP_006 KTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEAFSPRNAARISEKRKEYMDACGEANNQN 140 150 160 170 180 190 40 50 60 70 80 90 pF1KSD FQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAELE 200 210 220 230 240 250 100 110 120 130 140 150 pF1KSD NSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSIP 260 270 280 290 300 310 160 170 180 190 200 210 pF1KSD MQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQACQQKDVFANYLTSNFQAPGVKSGNKRSSSHSSPGSPKKQKNESNSAGSPADMELDSD 320 330 340 350 360 370 220 230 240 250 260 270 pF1KSD MEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEVPHGSQSSESFQFQPPLPPDTPPLPRGTPPPVFTPPLPKGTPPLTPSDSPQTRTASGA 380 390 400 410 420 430 280 290 300 310 320 330 pF1KSD VDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDEDALTLEELEEQQRRIWAALEQAESVNSDSDVPVDTPLTGNSVASSPCPNELDLPVPE 440 450 460 470 480 490 340 350 360 370 380 390 pF1KSD GKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKTSEKQTLDEPEVPEIFTKKSEAGHASSPDSEVTSLCQKEKAELAPVNTEGALLDNGSV 500 510 520 530 540 550 400 410 420 430 440 450 pF1KSD VPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPNCDISNGGSQKLFPADTSPSTATKIHSPIPDMSKFATGITPFEFENMAESTGMYLRIR 560 570 580 590 600 610 460 pF1KSD SLLKNSPRNQQKNKKASE :::::::::::::::::: XP_006 SLLKNSPRNQQKNKKASE 620 630 469 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:14:50 2016 done: Thu Nov 3 08:14:52 2016 Total Scan time: 12.190 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]