FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0042, 671 aa 1>>>pF1KSDB0042 671 - 671 aa - 671 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6329+/-0.000436; mu= 14.4703+/- 0.027 mean_var=132.6130+/-27.389, 0's: 0 Z-trim(114.8): 344 B-trim: 919 in 1/53 Lambda= 0.111373 statistics sampled from 24441 (24828) to 24441 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.291), width: 16 Scan time: 11.540 The best scores are: opt bits E(85289) XP_005262286 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 4461 728.9 1.4e-209 NP_542775 (OMIM: 300723) synaptotagmin-like protei ( 671) 4461 728.9 1.4e-209 XP_016885460 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 4461 728.9 1.4e-209 XP_011529370 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 4461 728.9 1.4e-209 NP_001123368 (OMIM: 300723) synaptotagmin-like pro ( 671) 4461 728.9 1.4e-209 NP_001167539 (OMIM: 300723) synaptotagmin-like pro ( 671) 4461 728.9 1.4e-209 XP_016885457 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 4127 675.3 2.1e-193 XP_016885456 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 4127 675.3 2.1e-193 XP_016885458 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 4127 675.3 2.1e-193 XP_016885459 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 4127 675.3 2.1e-193 XP_016885455 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 4127 675.3 2.1e-193 NP_001156423 (OMIM: 612880) synaptotagmin-like pro ( 934) 1040 179.4 5.4e-44 NP_001156425 (OMIM: 612880) synaptotagmin-like pro ( 935) 1040 179.4 5.4e-44 XP_016873425 (OMIM: 612880) PREDICTED: synaptotagm (2096) 1038 179.3 1.2e-43 XP_011543411 (OMIM: 612880) PREDICTED: synaptotagm (2190) 1038 179.4 1.3e-43 XP_016873423 (OMIM: 612880) PREDICTED: synaptotagm (2211) 1038 179.4 1.3e-43 XP_011543409 (OMIM: 612880) PREDICTED: synaptotagm (2212) 1038 179.4 1.3e-43 XP_011543408 (OMIM: 612880) PREDICTED: synaptotagm (2238) 1038 179.4 1.3e-43 XP_011543407 (OMIM: 612880) PREDICTED: synaptotagm (2239) 1038 179.4 1.3e-43 XP_016873428 (OMIM: 612880) PREDICTED: synaptotagm ( 445) 1023 176.4 2.1e-43 XP_016873426 (OMIM: 612880) PREDICTED: synaptotagm ( 876) 1026 177.1 2.5e-43 NP_001276537 (OMIM: 612880) synaptotagmin-like pro ( 902) 1026 177.1 2.5e-43 XP_005274119 (OMIM: 612880) PREDICTED: synaptotagm ( 924) 1026 177.1 2.6e-43 XP_005274118 (OMIM: 612880) PREDICTED: synaptotagm ( 950) 1026 177.1 2.6e-43 XP_005274117 (OMIM: 612880) PREDICTED: synaptotagm ( 951) 1026 177.1 2.6e-43 XP_016873429 (OMIM: 612880) PREDICTED: synaptotagm ( 429) 1018 175.5 3.5e-43 XP_016873422 (OMIM: 612880) PREDICTED: synaptotagm (2222) 1027 177.6 4.4e-43 XP_005274114 (OMIM: 612880) PREDICTED: synaptotagm (2223) 1027 177.6 4.4e-43 XP_016873424 (OMIM: 612880) PREDICTED: synaptotagm (2171) 1026 177.4 4.8e-43 NP_996812 (OMIM: 612880) synaptotagmin-like protei ( 376) 1002 172.9 1.9e-42 XP_005274124 (OMIM: 612880) PREDICTED: synaptotagm ( 376) 1002 172.9 1.9e-42 XP_011543410 (OMIM: 612880) PREDICTED: synaptotagm (2199) 995 172.5 1.5e-41 XP_011543416 (OMIM: 612880) PREDICTED: synaptotagm ( 365) 981 169.5 1.9e-41 NP_996813 (OMIM: 612880) synaptotagmin-like protei ( 365) 981 169.5 1.9e-41 XP_005274123 (OMIM: 612880) PREDICTED: synaptotagm ( 894) 976 169.1 6.6e-41 XP_016873427 (OMIM: 612880) PREDICTED: synaptotagm ( 862) 972 168.4 1e-40 NP_116561 (OMIM: 612880) synaptotagmin-like protei ( 910) 972 168.4 1e-40 XP_005274120 (OMIM: 612880) PREDICTED: synaptotagm ( 911) 972 168.4 1e-40 XP_011543417 (OMIM: 612880) PREDICTED: synaptotagm ( 325) 959 165.9 2.1e-40 XP_011543418 (OMIM: 612880) PREDICTED: synaptotagm ( 325) 959 165.9 2.1e-40 NP_001276539 (OMIM: 612880) synaptotagmin-like pro ( 336) 959 166.0 2.1e-40 NP_001156424 (OMIM: 612880) synaptotagmin-like pro ( 336) 959 166.0 2.1e-40 NP_001276538 (OMIM: 612880) synaptotagmin-like pro ( 255) 671 119.6 1.5e-26 NP_116261 (OMIM: 608042) synaptotagmin-like protei ( 550) 501 92.6 4.3e-18 NP_001180237 (OMIM: 608042) synaptotagmin-like pro ( 562) 501 92.6 4.4e-18 XP_006711053 (OMIM: 608042) PREDICTED: synaptotagm ( 582) 501 92.6 4.5e-18 XP_005246079 (OMIM: 608042) PREDICTED: synaptotagm ( 594) 501 92.6 4.6e-18 XP_011543412 (OMIM: 612880) PREDICTED: synaptotagm (2182) 399 76.7 1e-12 XP_006711054 (OMIM: 608042) PREDICTED: synaptotagm ( 355) 365 70.5 1.2e-11 NP_001268402 (OMIM: 606526,609227) melanophilin is ( 480) 286 58.0 9.8e-08 >>XP_005262286 (OMIM: 300723) PREDICTED: synaptotagmin-l (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_005 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: XP_005 RSSMAKQKLGL 670 >>NP_542775 (OMIM: 300723) synaptotagmin-like protein 4 (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_542 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: NP_542 RSSMAKQKLGL 670 >>XP_016885460 (OMIM: 300723) PREDICTED: synaptotagmin-l (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: XP_016 RSSMAKQKLGL 670 >>XP_011529370 (OMIM: 300723) PREDICTED: synaptotagmin-l (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: XP_011 RSSMAKQKLGL 670 >>NP_001123368 (OMIM: 300723) synaptotagmin-like protein (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: NP_001 RSSMAKQKLGL 670 >>NP_001167539 (OMIM: 300723) synaptotagmin-like protein (671 aa) initn: 4461 init1: 4461 opt: 4461 Z-score: 3883.4 bits: 728.9 E(85289): 1.4e-209 Smith-Waterman score: 4461; 99.9% identity (100.0% similar) in 671 aa overlap (1-671:1-671) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 610 620 630 640 650 660 670 pF1KSD RSSMAKQKLGL ::::::::::: NP_001 RSSMAKQKLGL 670 >>XP_016885457 (OMIM: 300723) PREDICTED: synaptotagmin-l (676 aa) initn: 4127 init1: 4127 opt: 4127 Z-score: 3593.3 bits: 675.3 E(85289): 2.1e-193 Smith-Waterman score: 4127; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::: XP_016 VWDREPLASNDFLGGVRLGVGTVNIQPILIECLLCARTRGRLSSCTDMCTDKCDPDCQEL 610 620 630 640 650 660 >>XP_016885456 (OMIM: 300723) PREDICTED: synaptotagmin-l (676 aa) initn: 4127 init1: 4127 opt: 4127 Z-score: 3593.3 bits: 675.3 E(85289): 2.1e-193 Smith-Waterman score: 4127; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::: XP_016 VWDREPLASNDFLGGVRLGVGTVNIQPILIECLLCARTRGRLSSCTDMCTDKCDPDCQEL 610 620 630 640 650 660 >>XP_016885458 (OMIM: 300723) PREDICTED: synaptotagmin-l (676 aa) initn: 4127 init1: 4127 opt: 4127 Z-score: 3593.3 bits: 675.3 E(85289): 2.1e-193 Smith-Waterman score: 4127; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::: XP_016 VWDREPLASNDFLGGVRLGVGTVNIQPILIECLLCARTRGRLSSCTDMCTDKCDPDCQEL 610 620 630 640 650 660 >>XP_016885459 (OMIM: 300723) PREDICTED: synaptotagmin-l (676 aa) initn: 4127 init1: 4127 opt: 4127 Z-score: 3593.3 bits: 675.3 E(85289): 2.1e-193 Smith-Waterman score: 4127; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KSD MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL :::::::::::::::::::::: XP_016 VWDREPLASNDFLGGVRLGVGTVNIQPILIECLLCARTRGRLSSCTDMCTDKCDPDCQEL 610 620 630 640 650 660 671 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:19:01 2016 done: Thu Nov 3 08:19:03 2016 Total Scan time: 11.540 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]