FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0055, 1332 aa 1>>>pF1KSDB0055 1332 - 1332 aa - 1332 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3366+/-0.00111; mu= 16.7598+/- 0.067 mean_var=71.5987+/-14.239, 0's: 0 Z-trim(102.3): 38 B-trim: 0 in 0/50 Lambda= 0.151573 statistics sampled from 6869 (6887) to 6869 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.212), width: 16 Scan time: 5.180 The best scores are: opt bits E(32554) CCDS6773.1 IKBKAP gene_id:8518|Hs108|chr9 (1332) 8889 1954.0 0 CCDS83394.1 IKBKAP gene_id:8518|Hs108|chr9 ( 983) 6525 1437.0 0 >>CCDS6773.1 IKBKAP gene_id:8518|Hs108|chr9 (1332 aa) initn: 8889 init1: 8889 opt: 8889 Z-score: 10493.5 bits: 1954.0 E(32554): 0 Smith-Waterman score: 8889; 100.0% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD VRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 VRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKA 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 ERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD DTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 DTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKI 1270 1280 1290 1300 1310 1320 1330 pF1KSD NRRTQWKLSLLD :::::::::::: CCDS67 NRRTQWKLSLLD 1330 >>CCDS83394.1 IKBKAP gene_id:8518|Hs108|chr9 (983 aa) initn: 6525 init1: 6525 opt: 6525 Z-score: 7702.0 bits: 1437.0 E(32554): 0 Smith-Waterman score: 6525; 100.0% identity (100.0% similar) in 983 aa overlap (350-1332:1-983) 320 330 340 350 360 370 pF1KSD VQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDR :::::::::::::::::::::::::::::: CCDS83 MWDPVTPYRLHVLCQGWHYLAYDWHWTTDR 10 20 30 380 390 400 410 420 430 pF1KSD SVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 SVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDL 40 50 60 70 80 90 440 450 460 470 480 490 pF1KSD AVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 AVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVN 100 110 120 130 140 150 500 510 520 530 540 550 pF1KSD PLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 PLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIIS 160 170 180 190 200 210 560 570 580 590 600 610 pF1KSD LCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 LCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEE 220 230 240 250 260 270 620 630 640 650 660 670 pF1KSD CVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 CVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSS 280 290 300 310 320 330 680 690 700 710 720 730 pF1KSD NHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 NHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFK 340 350 360 370 380 390 740 750 760 770 780 790 pF1KSD EAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 EAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPA 400 410 420 430 440 450 800 810 820 830 840 850 pF1KSD PVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 PVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVH 460 470 480 490 500 510 860 870 880 890 900 910 pF1KSD ELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 ELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLP 520 530 540 550 560 570 920 930 940 950 960 970 pF1KSD FLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 FLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYS 580 590 600 610 620 630 980 990 1000 1010 1020 1030 pF1KSD PSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 PSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLN 640 650 660 670 680 690 1040 1050 1060 1070 1080 1090 pF1KSD FTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 FTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKY 700 710 720 730 740 750 1100 1110 1120 1130 1140 1150 pF1KSD NRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 NRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPH 760 770 780 790 800 810 1160 1170 1180 1190 1200 1210 pF1KSD GQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 GQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALL 820 830 840 850 860 870 1220 1230 1240 1250 1260 1270 pF1KSD EALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 EALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQ 880 890 900 910 920 930 1280 1290 1300 1310 1320 1330 pF1KSD QNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 QNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD 940 950 960 970 980 1332 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:22:36 2016 done: Thu Nov 3 08:22:37 2016 Total Scan time: 5.180 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]