Result of FASTA (omim) for
pF1KSDB0055
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0055, 1332 aa
1>>>pF1KSDB0055 1332 - 1332 aa - 1332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0939+/-0.000474; mu= 18.4312+/- 0.029
mean_var=76.2152+/-15.748, 0's: 0 Z-trim(109.0): 54 B-trim: 764 in 2/49
Lambda= 0.146911
statistics sampled from 17136 (17165) to 17136 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.201), width: 16
Scan time: 13.180
The best scores are: opt bits E(85289)
NP_003631 (OMIM: 223900,603722) elongator complex (1332) 8889 1894.7 0
NP_001305289 (OMIM: 223900,603722) elongator compl (1218) 8150 1738.1 0
XP_011517438 (OMIM: 223900,603722) PREDICTED: elon (1346) 7514 1603.3 0
XP_011517439 (OMIM: 223900,603722) PREDICTED: elon (1232) 6775 1446.6 0
NP_001317678 (OMIM: 223900,603722) elongator compl ( 983) 6525 1393.6 0
>>NP_003631 (OMIM: 223900,603722) elongator complex prot (1332 aa)
initn: 8889 init1: 8889 opt: 8889 Z-score: 10173.1 bits: 1894.7 E(85289): 0
Smith-Waterman score: 8889; 100.0% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332)
10 20 30 40 50 60
pF1KSD MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD VRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD ERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKI
1270 1280 1290 1300 1310 1320
1330
pF1KSD NRRTQWKLSLLD
::::::::::::
NP_003 NRRTQWKLSLLD
1330
>>NP_001305289 (OMIM: 223900,603722) elongator complex p (1218 aa)
initn: 8150 init1: 8150 opt: 8150 Z-score: 9327.3 bits: 1738.1 E(85289): 0
Smith-Waterman score: 8150; 100.0% identity (100.0% similar) in 1218 aa overlap (115-1332:1-1218)
90 100 110 120 130 140
pF1KSD VATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPIL
::::::::::::::::::::::::::::::
NP_001 MSWSPDQELVLLATGQQTLIMMTKDFEPIL
10 20 30
150 160 170 180 190 200
pF1KSD EQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KSD QFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQD
100 110 120 130 140 150
270 280 290 300 310 320
pF1KSD IVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWT
160 170 180 190 200 210
330 340 350 360 370 380
pF1KSD VGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDN
220 230 240 250 260 270
390 400 410 420 430 440
pF1KSD SSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLAVLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLAVLDA
280 290 300 310 320 330
450 460 470 480 490 500
pF1KSD SNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPLKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPLKLG
340 350 360 370 380 390
510 520 530 540 550 560
pF1KSD LLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNS
400 410 420 430 440 450
570 580 590 600 610 620
pF1KSD KTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECVLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECVLGL
460 470 480 490 500 510
630 640 650 660 670 680
pF1KSD TDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNHVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNHVSH
520 530 540 550 560 570
690 700 710 720 730 740
pF1KSD GEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFEC
580 590 600 610 620 630
750 760 770 780 790 800
pF1KSD MRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPAPVTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPAPVTSS
640 650 660 670 680 690
810 820 830 840 850 860
pF1KSD VYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVHELQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVHELQGN
700 710 720 730 740 750
870 880 890 900 910 920
pF1KSD APSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLPFLNTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLPFLNTL
760 770 780 790 800 810
930 940 950 960 970 980
pF1KSD KKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYSPSSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYSPSSQQ
820 830 840 850 860 870
990 1000 1010 1020 1030 1040
pF1KSD YQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLNFTKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLNFTKDQ
880 890 900 910 920 930
1050 1060 1070 1080 1090 1100
pF1KSD LVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKYNRLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKYNRLDI
940 950 960 970 980 990
1110 1120 1130 1140 1150 1160
pF1KSD IETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESD
1000 1010 1020 1030 1040 1050
1170 1180 1190 1200 1210 1220
pF1KSD LFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSE
1060 1070 1080 1090 1100 1110
1230 1240 1250 1260 1270 1280
pF1KSD VVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSAT
1120 1130 1140 1150 1160 1170
1290 1300 1310 1320 1330
pF1KSD PVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD
1180 1190 1200 1210
>>XP_011517438 (OMIM: 223900,603722) PREDICTED: elongato (1346 aa)
initn: 7514 init1: 7514 opt: 7514 Z-score: 8598.1 bits: 1603.3 E(85289): 0
Smith-Waterman score: 8851; 99.0% identity (99.0% similar) in 1346 aa overlap (1-1332:1-1346)
10 20 30 40 50 60
pF1KSD MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHPVNQVTFLAHPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEKRYKIQFENNEDQDVNPLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCFCLRDASFKTLQAGLSSNHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLFFTELKEEDVTKTMYPAPVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KSD LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILE--------------AQKNYMAFLDS
::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 LLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEGEGSILDRIPHLEEAQKNYMAFLDS
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KSD QTATFSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTATFSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSN
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KSD SRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLF
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KSD EFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTS
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KSD VPVLDAELFIPPKINRRTQWKLSLLD
::::::::::::::::::::::::::
XP_011 VPVLDAELFIPPKINRRTQWKLSLLD
1330 1340
>>XP_011517439 (OMIM: 223900,603722) PREDICTED: elongato (1232 aa)
initn: 6775 init1: 6775 opt: 6775 Z-score: 7752.2 bits: 1446.6 E(85289): 0
Smith-Waterman score: 8112; 98.9% identity (98.9% similar) in 1232 aa overlap (115-1332:1-1232)
90 100 110 120 130 140
pF1KSD VATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPIL
::::::::::::::::::::::::::::::
XP_011 MSWSPDQELVLLATGQQTLIMMTKDFEPIL
10 20 30
150 160 170 180 190 200
pF1KSD EQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KSD QFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQD
100 110 120 130 140 150
270 280 290 300 310 320
pF1KSD IVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWT
160 170 180 190 200 210
330 340 350 360 370 380
pF1KSD VGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDN
220 230 240 250 260 270
390 400 410 420 430 440
pF1KSD SSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLAVLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLAVLDA
280 290 300 310 320 330
450 460 470 480 490 500
pF1KSD SNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPLKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPLKLG
340 350 360 370 380 390
510 520 530 540 550 560
pF1KSD LLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNS
400 410 420 430 440 450
570 580 590 600 610 620
pF1KSD KTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECVLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECVLGL
460 470 480 490 500 510
630 640 650 660 670 680
pF1KSD TDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNHVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNHVSH
520 530 540 550 560 570
690 700 710 720 730 740
pF1KSD GEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFEC
580 590 600 610 620 630
750 760 770 780 790 800
pF1KSD MRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPAPVTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPAPVTSS
640 650 660 670 680 690
810 820 830 840 850 860
pF1KSD VYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVHELQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVHELQGN
700 710 720 730 740 750
870 880 890 900 910 920
pF1KSD APSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLPFLNTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLPFLNTL
760 770 780 790 800 810
930 940 950 960 970 980
pF1KSD KKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYSPSSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYSPSSQQ
820 830 840 850 860 870
990 1000 1010 1020 1030 1040
pF1KSD YQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLNFTKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLNFTKDQ
880 890 900 910 920 930
1050 1060 1070 1080 1090 1100
pF1KSD LVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKYNRLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKYNRLDI
940 950 960 970 980 990
1110 1120 1130 1140 1150
pF1KSD IETNVKPSILE--------------AQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQ
::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 IETNVKPSILEGEGSILDRIPHLEEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQ
1000 1010 1020 1030 1040 1050
1160 1170 1180 1190 1200 1210
pF1KSD AGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEG
1060 1070 1080 1090 1100 1110
1220 1230 1240 1250 1260 1270
pF1KSD SPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSL
1120 1130 1140 1150 1160 1170
1280 1290 1300 1310 1320 1330
pF1KSD PEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSL
1180 1190 1200 1210 1220 1230
pF1KSD LD
::
XP_011 LD
>>NP_001317678 (OMIM: 223900,603722) elongator complex p (983 aa)
initn: 6525 init1: 6525 opt: 6525 Z-score: 7467.4 bits: 1393.6 E(85289): 0
Smith-Waterman score: 6525; 100.0% identity (100.0% similar) in 983 aa overlap (350-1332:1-983)
320 330 340 350 360 370
pF1KSD VQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDR
::::::::::::::::::::::::::::::
NP_001 MWDPVTPYRLHVLCQGWHYLAYDWHWTTDR
10 20 30
380 390 400 410 420 430
pF1KSD SVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDL
40 50 60 70 80 90
440 450 460 470 480 490
pF1KSD AVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVN
100 110 120 130 140 150
500 510 520 530 540 550
pF1KSD PLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLKLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIIS
160 170 180 190 200 210
560 570 580 590 600 610
pF1KSD LCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEE
220 230 240 250 260 270
620 630 640 650 660 670
pF1KSD CVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSS
280 290 300 310 320 330
680 690 700 710 720 730
pF1KSD NHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFK
340 350 360 370 380 390
740 750 760 770 780 790
pF1KSD EAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPA
400 410 420 430 440 450
800 810 820 830 840 850
pF1KSD PVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQKVH
460 470 480 490 500 510
860 870 880 890 900 910
pF1KSD ELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLP
520 530 540 550 560 570
920 930 940 950 960 970
pF1KSD FLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYS
580 590 600 610 620 630
980 990 1000 1010 1020 1030
pF1KSD PSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQALCVAAQLN
640 650 660 670 680 690
1040 1050 1060 1070 1080 1090
pF1KSD FTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRLVYKY
700 710 720 730 740 750
1100 1110 1120 1130 1140 1150
pF1KSD NRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKEQAQQAGLDDEVPH
760 770 780 790 800 810
1160 1170 1180 1190 1200 1210
pF1KSD GQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALL
820 830 840 850 860 870
1220 1230 1240 1250 1260 1270
pF1KSD EALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQ
880 890 900 910 920 930
1280 1290 1300 1310 1320 1330
pF1KSD QNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD
940 950 960 970 980
1332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:22:37 2016 done: Thu Nov 3 08:22:39 2016
Total Scan time: 13.180 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]