FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0058, 1101 aa 1>>>pF1KSDB0058 1101 - 1101 aa - 1101 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3745+/-0.00111; mu= 16.4280+/- 0.066 mean_var=82.1846+/-16.374, 0's: 0 Z-trim(103.6): 25 B-trim: 3 in 1/49 Lambda= 0.141475 statistics sampled from 7464 (7467) to 7464 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.229), width: 16 Scan time: 4.690 The best scores are: opt bits E(32554) CCDS11412.1 ACLY gene_id:47|Hs108|chr17 (1101) 7328 1506.4 0 CCDS11413.1 ACLY gene_id:47|Hs108|chr17 (1091) 4132 854.1 0 CCDS1967.2 SUCLG1 gene_id:8802|Hs108|chr2 ( 346) 302 72.2 2.3e-12 >>CCDS11412.1 ACLY gene_id:47|Hs108|chr17 (1101 aa) initn: 7328 init1: 7328 opt: 7328 Z-score: 8077.4 bits: 1506.4 E(32554): 0 Smith-Waterman score: 7328; 100.0% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: CCDS11 QGLYRHPWDDISYVLPEHMSM 1090 1100 >>CCDS11413.1 ACLY gene_id:47|Hs108|chr17 (1091 aa) initn: 4118 init1: 4118 opt: 4132 Z-score: 4552.1 bits: 854.1 E(32554): 0 Smith-Waterman score: 7231; 99.1% identity (99.1% similar) in 1101 aa overlap (1-1101:1-1091) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQ---- 430 440 450 460 470 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ------GKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1020 1030 1040 1050 1060 1070 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: CCDS11 QGLYRHPWDDISYVLPEHMSM 1080 1090 >>CCDS1967.2 SUCLG1 gene_id:8802|Hs108|chr2 (346 aa) initn: 245 init1: 164 opt: 302 Z-score: 335.4 bits: 72.2 E(32554): 2.3e-12 Smith-Waterman score: 315; 26.1% identity (54.1% similar) in 333 aa overlap (474-802:33-341) 450 460 470 480 490 500 pF1KSD STSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWG .::... ... ...:: : : CCDS19 ATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIICQG 10 20 30 40 50 60 510 520 530 540 550 560 pF1KSD MQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKH . . :: . . . :.. . : : :. .. .:::... .: ... CCDS19 FTGK--QGTFHSQQALEYGTKLVGGTT-PGKG--------GQTHLGLPVFNTVKEA-KEQ 70 80 90 100 110 570 580 590 600 610 620 pF1KSD PEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEA-LTRKLIKKADQKGVTIIG . . . .. : . :... :.: .. :.::::. ..: : :. . .:: CCDS19 TGATASVIYVPPPFAAAAINEAIE-AEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIG 120 130 140 150 160 630 640 650 660 670 680 pF1KSD PATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVY : : :.:: ::: :. ..... : .. ::::: .. : . ... : CCDS19 PNCPGVINPGECKIG--------IMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQS 170 180 190 200 210 220 690 700 710 720 730 pF1KSD EGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKE---GRLTKP :.:::: . :. :.: . . . ... :...:::::. : . . .:. : .:: CCDS19 LCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKP 230 240 250 260 270 280 740 750 760 770 780 790 pF1KSD IVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQS .: . : : ..::::: .. : : .::. ::: : : .:: : . CCDS19 VVSFIAGLTAP---PGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYK 290 300 310 320 330 800 810 820 830 840 850 pF1KSD VYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPI .: CCDS19 EFEKRKML 340 1101 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:24:00 2016 done: Thu Nov 3 08:24:01 2016 Total Scan time: 4.690 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]