FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0058, 1101 aa 1>>>pF1KSDB0058 1101 - 1101 aa - 1101 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7330+/-0.000478; mu= 14.3284+/- 0.030 mean_var=91.8485+/-19.148, 0's: 0 Z-trim(110.8): 16 B-trim: 753 in 1/53 Lambda= 0.133825 statistics sampled from 19240 (19249) to 19240 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.226), width: 16 Scan time: 11.890 The best scores are: opt bits E(85289) NP_001087 (OMIM: 108728) ATP-citrate synthase isof (1101) 7328 1426.1 0 XP_005257452 (OMIM: 108728) PREDICTED: ATP-citrate (1101) 7328 1426.1 0 NP_001290203 (OMIM: 108728) ATP-citrate synthase i (1155) 7328 1426.1 0 NP_942127 (OMIM: 108728) ATP-citrate synthase isof (1091) 4132 809.1 0 XP_016880177 (OMIM: 108728) PREDICTED: ATP-citrate (1091) 4132 809.1 0 NP_001290204 (OMIM: 108728) ATP-citrate synthase i (1145) 4132 809.1 0 NP_003840 (OMIM: 245400,611224) succinate--CoA lig ( 346) 302 69.5 4e-11 >>NP_001087 (OMIM: 108728) ATP-citrate synthase isoform (1101 aa) initn: 7328 init1: 7328 opt: 7328 Z-score: 7643.7 bits: 1426.1 E(85289): 0 Smith-Waterman score: 7328; 100.0% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: NP_001 QGLYRHPWDDISYVLPEHMSM 1090 1100 >>XP_005257452 (OMIM: 108728) PREDICTED: ATP-citrate syn (1101 aa) initn: 7328 init1: 7328 opt: 7328 Z-score: 7643.7 bits: 1426.1 E(85289): 0 Smith-Waterman score: 7328; 100.0% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: XP_005 QGLYRHPWDDISYVLPEHMSM 1090 1100 >>NP_001290203 (OMIM: 108728) ATP-citrate synthase isofo (1155 aa) initn: 7328 init1: 7328 opt: 7328 Z-score: 7643.4 bits: 1426.1 E(85289): 0 Smith-Waterman score: 7328; 100.0% identity (100.0% similar) in 1101 aa overlap (1-1101:55-1155) 10 20 30 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFK :::::::::::::::::::::::::::::: NP_001 LRILRGSSGLWKKRRARTSAETGRAGLSAAMSAKAISEQTGKELLYKFICTTSAIQNRFK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD YARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD QEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQ 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD KLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKD 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD GVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD PKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTRE 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD KHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRV 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD MGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAP 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD SRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWGMQTRAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWGMQTRAVQ 510 520 530 540 550 560 520 530 540 550 560 570 pF1KSD GMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLI 570 580 590 600 610 620 580 590 600 610 620 630 pF1KSD NFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIK 630 640 650 660 670 680 640 650 660 670 680 690 pF1KSD PGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGD 690 700 710 720 730 740 700 710 720 730 740 750 pF1KSD RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCAT 750 760 770 780 790 800 760 770 780 790 800 810 pF1KSD MFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVI 810 820 830 840 850 860 820 830 840 850 860 870 pF1KSD VPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIG 870 880 890 900 910 920 880 890 900 910 920 930 pF1KSD GVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLT 930 940 950 960 970 980 940 950 960 970 980 990 pF1KSD IGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQIL 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KSD KDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADE 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 pF1KSD YIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM 1110 1120 1130 1140 1150 >>NP_942127 (OMIM: 108728) ATP-citrate synthase isoform (1091 aa) initn: 4118 init1: 4118 opt: 4132 Z-score: 4309.0 bits: 809.1 E(85289): 0 Smith-Waterman score: 7231; 99.1% identity (99.1% similar) in 1101 aa overlap (1-1101:1-1091) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQ---- 430 440 450 460 470 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 ------GKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_942 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1020 1030 1040 1050 1060 1070 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: NP_942 QGLYRHPWDDISYVLPEHMSM 1080 1090 >>XP_016880177 (OMIM: 108728) PREDICTED: ATP-citrate syn (1091 aa) initn: 4118 init1: 4118 opt: 4132 Z-score: 4309.0 bits: 809.1 E(85289): 0 Smith-Waterman score: 7231; 99.1% identity (99.1% similar) in 1101 aa overlap (1-1101:1-1091) 10 20 30 40 50 60 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQ---- 430 440 450 460 470 490 500 510 520 530 540 pF1KSD SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ------GKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK 1020 1030 1040 1050 1060 1070 1090 1100 pF1KSD QGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::: XP_016 QGLYRHPWDDISYVLPEHMSM 1080 1090 >>NP_001290204 (OMIM: 108728) ATP-citrate synthase isofo (1145 aa) initn: 4118 init1: 4118 opt: 4132 Z-score: 4308.6 bits: 809.1 E(85289): 0 Smith-Waterman score: 7231; 99.1% identity (99.1% similar) in 1101 aa overlap (1-1101:55-1145) 10 20 30 pF1KSD MSAKAISEQTGKELLYKFICTTSAIQNRFK :::::::::::::::::::::::::::::: NP_001 LRILRGSSGLWKKRRARTSAETGRAGLSAAMSAKAISEQTGKELLYKFICTTSAIQNRFK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD YARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD QEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQ 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD KLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKD 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD GVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD PKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTRE 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD KHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRV 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD MGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAP 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD SRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWGMQTRAVQ :::::::::::::::::::::::::: :::::::::::::::::::::::: NP_001 SRTASFSESRADEVAPAKKAKPAMPQ----------GKSTTLFSRHTKAIVWGMQTRAVQ 510 520 530 540 550 520 530 540 550 560 570 pF1KSD GMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLI 560 570 580 590 600 610 580 590 600 610 620 630 pF1KSD NFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIK 620 630 640 650 660 670 640 650 660 670 680 690 pF1KSD PGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGD 680 690 700 710 720 730 700 710 720 730 740 750 pF1KSD RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCAT 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD MFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVI 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD VPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIG 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD GVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLT 920 930 940 950 960 970 940 950 960 970 980 990 pF1KSD IGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQIL 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KSD KDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADE 1040 1050 1060 1070 1080 1090 1060 1070 1080 1090 1100 pF1KSD YIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM 1100 1110 1120 1130 1140 >>NP_003840 (OMIM: 245400,611224) succinate--CoA ligase (346 aa) initn: 245 init1: 164 opt: 302 Z-score: 320.7 bits: 69.5 E(85289): 4e-11 Smith-Waterman score: 315; 26.1% identity (54.1% similar) in 333 aa overlap (474-802:33-341) 450 460 470 480 490 500 pF1KSD STSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWG .::... ... ...:: : : NP_003 ATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIICQG 10 20 30 40 50 60 510 520 530 540 550 560 pF1KSD MQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKH . . :: . . . :.. . : : :. .. .:::... .: ... NP_003 FTGK--QGTFHSQQALEYGTKLVGGTT-PGKG--------GQTHLGLPVFNTVKEA-KEQ 70 80 90 100 110 570 580 590 600 610 620 pF1KSD PEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEA-LTRKLIKKADQKGVTIIG . . . .. : . :... :.: .. :.::::. ..: : :. . .:: NP_003 TGATASVIYVPPPFAAAAINEAIE-AEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIG 120 130 140 150 160 630 640 650 660 670 680 pF1KSD PATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVY : : :.:: ::: :. ..... : .. ::::: .. : . ... : NP_003 PNCPGVINPGECKIG--------IMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQS 170 180 190 200 210 220 690 700 710 720 730 pF1KSD EGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKE---GRLTKP :.:::: . :. :.: . . . ... :...:::::. : . . .:. : .:: NP_003 LCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKP 230 240 250 260 270 280 740 750 760 770 780 790 pF1KSD IVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQS .: . : : ..::::: .. : : .::. ::: : : .:: : . NP_003 VVSFIAGLTAP---PGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYK 290 300 310 320 330 800 810 820 830 840 850 pF1KSD VYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPI .: NP_003 EFEKRKML 340 1101 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:24:02 2016 done: Thu Nov 3 08:24:03 2016 Total Scan time: 11.890 Total Display time: 0.350 Function used was FASTA [36.3.4 Apr, 2011]