FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0059, 1137 aa 1>>>pF1KSDB0059 1137 - 1137 aa - 1137 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1554+/-0.000361; mu= 23.7425+/- 0.023 mean_var=80.4756+/-16.008, 0's: 0 Z-trim(114.4): 97 B-trim: 0 in 0/50 Lambda= 0.142969 statistics sampled from 24135 (24233) to 24135 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.284), width: 16 Scan time: 11.850 The best scores are: opt bits E(85289) NP_002197 (OMIM: 600536,613204) integrin alpha-7 i (1137) 7704 1599.6 0 XP_005268899 (OMIM: 600536,613204) PREDICTED: inte (1131) 7646 1587.6 0 NP_001138468 (OMIM: 600536,613204) integrin alpha- (1141) 7444 1546.0 0 XP_005268903 (OMIM: 600536,613204) PREDICTED: inte (1024) 6930 1439.9 0 XP_005268907 (OMIM: 600536,613204) PREDICTED: inte ( 979) 6625 1377.0 0 NP_001138469 (OMIM: 600536,613204) integrin alpha- (1044) 6509 1353.1 0 XP_005268905 (OMIM: 600536,613204) PREDICTED: inte (1023) 6142 1277.4 0 XP_005268906 (OMIM: 600536,613204) PREDICTED: inte (1023) 6142 1277.4 0 XP_016874754 (OMIM: 600536,613204) PREDICTED: inte (1051) 6142 1277.4 0 XP_005268901 (OMIM: 600536,613204) PREDICTED: inte (1068) 6142 1277.4 0 XP_005268896 (OMIM: 600536,613204) PREDICTED: inte (1181) 6142 1277.4 0 XP_005268897 (OMIM: 600536,613204) PREDICTED: inte (1175) 6091 1266.9 0 XP_005268898 (OMIM: 600536,613204) PREDICTED: inte (1162) 5633 1172.4 0 NP_000201 (OMIM: 147556,226730) integrin alpha-6 i (1073) 3020 633.5 2.1e-180 NP_001073286 (OMIM: 147556,226730) integrin alpha- (1091) 3020 633.5 2.2e-180 XP_006712574 (OMIM: 147556,226730) PREDICTED: inte (1058) 2987 626.6 2.4e-178 XP_006712573 (OMIM: 147556,226730) PREDICTED: inte (1076) 2987 626.7 2.4e-178 NP_001303235 (OMIM: 147556,226730) integrin alpha- ( 954) 2582 543.1 3.1e-153 XP_016859496 (OMIM: 147556,226730) PREDICTED: inte ( 959) 2471 520.2 2.4e-146 XP_016859494 (OMIM: 147556,226730) PREDICTED: inte ( 977) 2471 520.2 2.4e-146 XP_016859497 (OMIM: 147556,226730) PREDICTED: inte ( 944) 2465 518.9 5.6e-146 XP_016859495 (OMIM: 147556,226730) PREDICTED: inte ( 962) 2465 518.9 5.7e-146 NP_002198 (OMIM: 603963) integrin alpha-9 precurso (1035) 811 177.8 3e-43 XP_011518054 (OMIM: 191830,604063) PREDICTED: inte ( 799) 633 141.0 2.8e-32 NP_000876 (OMIM: 192975) integrin alpha-4 isoform (1032) 634 141.3 2.9e-32 XP_016858112 (OMIM: 604042) PREDICTED: integrin al (1180) 594 133.1 9.8e-30 XP_016858116 (OMIM: 604042) PREDICTED: integrin al ( 835) 592 132.6 1e-29 XP_011544151 (OMIM: 153370) PREDICTED: integrin al (1074) 559 125.8 1.4e-27 XP_006721107 (OMIM: 153370) PREDICTED: integrin al (1087) 559 125.9 1.4e-27 NP_002200 (OMIM: 153370) integrin alpha-L isoform (1170) 559 125.9 1.4e-27 XP_005254285 (OMIM: 604789) PREDICTED: integrin al (1086) 553 124.6 3.2e-27 XP_011519665 (OMIM: 604789) PREDICTED: integrin al (1119) 553 124.6 3.3e-27 NP_001004439 (OMIM: 604789) integrin alpha-11 prec (1188) 553 124.7 3.5e-27 NP_001107852 (OMIM: 153370) integrin alpha-L isofo (1086) 552 124.4 3.7e-27 XP_005255370 (OMIM: 153370) PREDICTED: integrin al (1169) 552 124.4 3.9e-27 XP_005257365 (OMIM: 605025,614748) PREDICTED: inte ( 916) 549 123.7 5e-27 NP_002195 (OMIM: 605025,614748) integrin alpha-3 p (1051) 549 123.8 5.6e-27 NP_000623 (OMIM: 120980,609939) integrin alpha-M i (1152) 468 107.1 6.4e-22 XP_016878705 (OMIM: 120980,609939) PREDICTED: inte ( 917) 466 106.6 7.2e-22 XP_011544152 (OMIM: 120980,609939) PREDICTED: inte (1091) 466 106.7 8.2e-22 NP_001139280 (OMIM: 120980,609939) integrin alpha- (1153) 466 106.7 8.5e-22 XP_011544154 (OMIM: 151510) PREDICTED: integrin al ( 798) 446 102.4 1.1e-20 NP_000878 (OMIM: 151510) integrin alpha-X isoform (1163) 446 102.6 1.5e-20 NP_001273304 (OMIM: 151510) integrin alpha-X isofo (1169) 446 102.6 1.5e-20 XP_016880076 (OMIM: 604682) PREDICTED: integrin al ( 848) 442 101.6 2.1e-20 XP_011522130 (OMIM: 604682) PREDICTED: integrin al (1137) 442 101.7 2.6e-20 XP_011522129 (OMIM: 604682) PREDICTED: integrin al (1163) 442 101.7 2.7e-20 NP_002199 (OMIM: 604682) integrin alpha-E precurso (1179) 442 101.8 2.7e-20 XP_011522127 (OMIM: 604682) PREDICTED: integrin al (1185) 442 101.8 2.7e-20 XP_016880075 (OMIM: 604682) PREDICTED: integrin al (1191) 442 101.8 2.7e-20 >>NP_002197 (OMIM: 600536,613204) integrin alpha-7 isofo (1137 aa) initn: 7704 init1: 7704 opt: 7704 Z-score: 8580.8 bits: 1599.6 E(85289): 0 Smith-Waterman score: 7704; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:1-1137) 10 20 30 40 50 60 pF1KSD MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KSD VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1090 1100 1110 1120 1130 >>XP_005268899 (OMIM: 600536,613204) PREDICTED: integrin (1131 aa) initn: 4112 init1: 4112 opt: 7646 Z-score: 8516.1 bits: 1587.6 E(85289): 0 Smith-Waterman score: 7646; 99.5% identity (99.5% similar) in 1137 aa overlap (1-1137:1-1131) 10 20 30 40 50 60 pF1KSD MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV :::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_005 VSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTV------DADTDRRLRGQV 490 500 510 520 530 550 560 570 580 590 600 pF1KSD PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSD 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKV 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVI 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHA 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 pF1KSD VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1080 1090 1100 1110 1120 1130 >>NP_001138468 (OMIM: 600536,613204) integrin alpha-7 is (1141 aa) initn: 7454 init1: 5898 opt: 7444 Z-score: 8290.9 bits: 1546.0 E(85289): 0 Smith-Waterman score: 7444; 97.0% identity (97.3% similar) in 1148 aa overlap (1-1137:1-1141) 10 20 30 40 50 60 pF1KSD MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 130 140 150 160 170 180 190 200 210 220 230 pF1KSD WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVT-----NIDSSD :::::::::::::::::::::::::::::::::::::::::::: : . : . NP_001 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH 190 200 210 220 230 240 240 250 260 270 280 pF1KSD PDQLVY-----KTLDPADRL-PGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRAN :. : : :: :: : :: :::.:::::::::::::::::::::::::: NP_001 LDDGPYEAGGEKEQDP--RLIPVPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRAN 250 260 270 280 290 290 300 310 320 330 340 pF1KSD HKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KSD ELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDG 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD KVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF 420 430 440 450 460 470 470 480 490 500 510 520 pF1KSD RARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLD 480 490 500 510 520 530 530 540 550 560 570 580 pF1KSD ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAI 540 550 560 570 580 590 590 600 610 620 630 640 pF1KSD VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 600 610 620 630 640 650 650 660 670 680 690 700 pF1KSD VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 660 670 680 690 700 710 710 720 730 740 750 760 pF1KSD EAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTS 720 730 740 750 760 770 770 780 790 800 810 820 pF1KSD GISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERA 780 790 800 810 820 830 830 840 850 860 870 880 pF1KSD MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP 840 850 860 870 880 890 890 900 910 920 930 940 pF1KSD GQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLD 900 910 920 930 940 950 950 960 970 980 990 1000 pF1KSD CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK 960 970 980 990 1000 1010 1010 1020 1030 1040 1050 1060 pF1KSD NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 1110 1120 pF1KSD HPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPD 1080 1090 1100 1110 1120 1130 1130 pF1KSD GHPGPGTA :::::::: NP_001 GHPGPGTA 1140 >>XP_005268903 (OMIM: 600536,613204) PREDICTED: integrin (1024 aa) initn: 6930 init1: 6930 opt: 6930 Z-score: 7718.6 bits: 1439.9 E(85289): 0 Smith-Waterman score: 6930; 100.0% identity (100.0% similar) in 1024 aa overlap (114-1137:1-1024) 90 100 110 120 130 140 pF1KSD QANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHR :::::::::::::::::::::::::::::: XP_005 MQKESKENQWLGVSVRSQGPGGKIVTCAHR 10 20 30 150 160 170 180 190 200 pF1KSD YEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KSD AFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYL 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD GFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYS 160 170 180 190 200 210 330 340 350 360 370 380 pF1KSD LAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGI 220 230 240 250 260 270 390 400 410 420 430 440 pF1KSD SLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSL 280 290 300 310 320 330 450 460 470 480 490 500 pF1KSD SGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCV 340 350 360 370 380 390 510 520 530 540 550 560 pF1KSD DLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWL 400 410 420 430 440 450 570 580 590 600 610 620 pF1KSD KHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQP 460 470 480 490 500 510 630 640 650 660 670 680 pF1KSD STQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQP 520 530 540 550 560 570 690 700 710 720 730 740 pF1KSD VIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENA 580 590 600 610 620 630 750 760 770 780 790 800 pF1KSD SHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 640 650 660 670 680 690 810 820 830 840 850 860 pF1KSD ELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNI 700 710 720 730 740 750 870 880 890 900 910 920 pF1KSD MWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE 760 770 780 790 800 810 930 940 950 960 970 980 pF1KSD PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNST 820 830 840 850 860 870 990 1000 1010 1020 1030 1040 pF1KSD FLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILL 880 890 900 910 920 930 1050 1060 1070 1080 1090 1100 pF1KSD AVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNN 940 950 960 970 980 990 1110 1120 1130 pF1KSD WGSPRREGPDAHPILAADGHPELGPDGHPGPGTA :::::::::::::::::::::::::::::::::: XP_005 WGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1000 1010 1020 >>XP_005268907 (OMIM: 600536,613204) PREDICTED: integrin (979 aa) initn: 6625 init1: 6625 opt: 6625 Z-score: 7378.8 bits: 1377.0 E(85289): 0 Smith-Waterman score: 6625; 100.0% identity (100.0% similar) in 979 aa overlap (159-1137:1-979) 130 140 150 160 170 180 pF1KSD RSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRP :::::::::::::::::::::::::::::: XP_005 MIGRCFVLSQDLAIRDELDGGEWKFCEGRP 10 20 30 190 200 210 220 230 240 pF1KSD QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPAD 40 50 60 70 80 90 250 260 270 280 290 300 pF1KSD RLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 100 110 120 130 140 150 310 320 330 340 350 360 pF1KSD VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 160 170 180 190 200 210 370 380 390 400 410 420 pF1KSD SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV 220 230 240 250 260 270 430 440 450 460 470 480 pF1KSD LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 280 290 300 310 320 330 490 500 510 520 530 540 pF1KSD DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR 340 350 360 370 380 390 550 560 570 580 590 600 pF1KSD NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG 400 410 420 430 440 450 610 620 630 640 650 660 pF1KSD QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM 460 470 480 490 500 510 670 680 690 700 710 720 pF1KSD DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA 520 530 540 550 560 570 730 740 750 760 770 780 pF1KSD LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 580 590 600 610 620 630 790 800 810 820 830 840 pF1KSD EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 640 650 660 670 680 690 850 860 870 880 890 900 pF1KSD QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 700 710 720 730 740 750 910 920 930 940 950 960 pF1KSD RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 760 770 780 790 800 810 970 980 990 1000 1010 1020 pF1KSD RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 820 830 840 850 860 870 1030 1040 1050 1060 1070 1080 pF1KSD MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 880 890 900 910 920 930 1090 1100 1110 1120 1130 pF1KSD QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 940 950 960 970 >>NP_001138469 (OMIM: 600536,613204) integrin alpha-7 is (1044 aa) initn: 6511 init1: 5898 opt: 6509 Z-score: 7249.1 bits: 1353.1 E(85289): 0 Smith-Waterman score: 6509; 94.7% identity (95.8% similar) in 1036 aa overlap (114-1137:17-1044) 90 100 110 120 130 140 pF1KSD QANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQ-WLGVSVRSQGPGGKIVTCAH .:.... : : ..: . :: :::: NP_001 MAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGK-ETCAH 10 20 30 40 150 160 170 180 190 200 pF1KSD RYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTA 50 60 70 80 90 100 210 220 230 240 250 pF1KSD AAFSPDSHYLLFGAPGTYNWKGLLFVT-----NIDSSDPDQLVY-----KTLDPADRL-P :::::::::::::::::::::: : . : . :. : : :: :: : NP_001 AAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDP--RLIP 110 120 130 140 150 160 260 270 280 290 300 310 pF1KSD GPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML :: :::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 170 180 190 200 210 320 330 340 350 360 370 pF1KSD SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KSD RLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEG 280 290 300 310 320 330 440 450 460 470 480 490 pF1KSD EAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLE 340 350 360 370 380 390 500 510 520 530 540 550 pF1KSD QPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLE 400 410 420 430 440 450 560 570 580 590 600 610 pF1KSD EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGL 460 470 480 490 500 510 620 630 640 650 660 670 pF1KSD PPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVD 520 530 540 550 560 570 680 690 700 710 720 730 pF1KSD GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDP 580 590 600 610 620 630 740 750 760 770 780 790 pF1KSD AEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE 640 650 660 670 680 690 800 810 820 830 840 850 pF1KSD LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQ 700 710 720 730 740 750 860 870 880 890 900 910 pF1KSD SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDR 760 770 780 790 800 810 920 930 940 950 960 970 pF1KSD RRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAA 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KSD VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAV 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KSD VAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQF 940 950 960 970 980 990 1100 1110 1120 1130 pF1KSD KEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1000 1010 1020 1030 1040 >>XP_005268905 (OMIM: 600536,613204) PREDICTED: integrin (1023 aa) initn: 6142 init1: 6142 opt: 6142 Z-score: 6840.2 bits: 1277.4 E(85289): 0 Smith-Waterman score: 6527; 95.7% identity (95.7% similar) in 1023 aa overlap (159-1137:1-1023) 130 140 150 160 170 180 pF1KSD RSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRP :::::::::::::::::::::::::::::: XP_005 MIGRCFVLSQDLAIRDELDGGEWKFCEGRP 10 20 30 190 200 210 220 pF1KSD QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG------------------------ :::::::::::::::::::::::::::::::::::: XP_005 QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEA 40 50 60 70 80 90 230 240 250 260 pF1KSD --------------------LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLG :::::::::::::::::::::::::::::::::::::::: XP_005 GGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLG 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD FSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSL 160 170 180 190 200 210 330 340 350 360 370 380 pF1KSD AVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGIS 220 230 240 250 260 270 390 400 410 420 430 440 pF1KSD LAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLS 280 290 300 310 320 330 450 460 470 480 490 500 pF1KSD GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVD 340 350 360 370 380 390 510 520 530 540 550 560 pF1KSD LRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLK 400 410 420 430 440 450 570 580 590 600 610 620 pF1KSD HQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPS 460 470 480 490 500 510 630 640 650 660 670 680 pF1KSD TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPV 520 530 540 550 560 570 690 700 710 720 730 740 pF1KSD IGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENAS 580 590 600 610 620 630 750 760 770 780 790 800 pF1KSD HVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIE 640 650 660 670 680 690 810 820 830 840 850 860 pF1KSD LPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIM 700 710 720 730 740 750 870 880 890 900 910 920 pF1KSD WPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP 760 770 780 790 800 810 930 940 950 960 970 980 pF1KSD GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTF 820 830 840 850 860 870 990 1000 1010 1020 1030 1040 pF1KSD LEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLA 880 890 900 910 920 930 1050 1060 1070 1080 1090 1100 pF1KSD VLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNW 940 950 960 970 980 990 1110 1120 1130 pF1KSD GSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::: XP_005 GSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1000 1010 1020 >>XP_005268906 (OMIM: 600536,613204) PREDICTED: integrin (1023 aa) initn: 6142 init1: 6142 opt: 6142 Z-score: 6840.2 bits: 1277.4 E(85289): 0 Smith-Waterman score: 6527; 95.7% identity (95.7% similar) in 1023 aa overlap (159-1137:1-1023) 130 140 150 160 170 180 pF1KSD RSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRP :::::::::::::::::::::::::::::: XP_005 MIGRCFVLSQDLAIRDELDGGEWKFCEGRP 10 20 30 190 200 210 220 pF1KSD QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG------------------------ :::::::::::::::::::::::::::::::::::: XP_005 QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEA 40 50 60 70 80 90 230 240 250 260 pF1KSD --------------------LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLG :::::::::::::::::::::::::::::::::::::::: XP_005 GGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLG 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD FSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSL 160 170 180 190 200 210 330 340 350 360 370 380 pF1KSD AVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGIS 220 230 240 250 260 270 390 400 410 420 430 440 pF1KSD LAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLS 280 290 300 310 320 330 450 460 470 480 490 500 pF1KSD GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVD 340 350 360 370 380 390 510 520 530 540 550 560 pF1KSD LRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLK 400 410 420 430 440 450 570 580 590 600 610 620 pF1KSD HQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPS 460 470 480 490 500 510 630 640 650 660 670 680 pF1KSD TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPV 520 530 540 550 560 570 690 700 710 720 730 740 pF1KSD IGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENAS 580 590 600 610 620 630 750 760 770 780 790 800 pF1KSD HVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIE 640 650 660 670 680 690 810 820 830 840 850 860 pF1KSD LPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIM 700 710 720 730 740 750 870 880 890 900 910 920 pF1KSD WPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP 760 770 780 790 800 810 930 940 950 960 970 980 pF1KSD GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTF 820 830 840 850 860 870 990 1000 1010 1020 1030 1040 pF1KSD LEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLA 880 890 900 910 920 930 1050 1060 1070 1080 1090 1100 pF1KSD VLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNW 940 950 960 970 980 990 1110 1120 1130 pF1KSD GSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::: XP_005 GSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1000 1010 1020 >>XP_016874754 (OMIM: 600536,613204) PREDICTED: integrin (1051 aa) initn: 6142 init1: 6142 opt: 6142 Z-score: 6840.0 bits: 1277.4 E(85289): 0 Smith-Waterman score: 6663; 95.8% identity (95.8% similar) in 1043 aa overlap (139-1137:9-1051) 110 120 130 140 150 160 pF1KSD DQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQ :::::::::::::::::::::::::::::: XP_016 MDLCNTGRTCAHRYEARQRVDQILETRDMIGRCFVLSQ 10 20 30 170 180 190 200 210 220 pF1KSD DLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARV 40 50 60 70 80 90 230 240 pF1KSD ----------------------------------------LLFVTNIDSSDPDQLVYKTL :::::::::::::::::::: XP_016 ELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KSD DPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASR 160 170 180 190 200 210 310 320 330 340 350 360 pF1KSD LVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGH 220 230 240 250 260 270 370 380 390 400 410 420 pF1KSD WAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAK 280 290 300 310 320 330 430 440 450 460 470 480 pF1KSD PSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 340 350 360 370 380 390 490 500 510 520 530 540 pF1KSD PRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVT 400 410 420 430 440 450 550 560 570 580 590 600 pF1KSD FLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRR 460 470 480 490 500 510 610 620 630 640 650 660 pF1KSD QAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQ 520 530 540 550 560 570 670 680 690 700 710 720 pF1KSD PLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYS 580 590 600 610 620 630 730 740 750 760 770 780 pF1KSD GVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL 640 650 660 670 680 690 790 800 810 820 830 840 pF1KSD ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEV 700 710 720 730 740 750 850 860 870 880 890 900 pF1KSD TVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHL 760 770 780 790 800 810 910 920 930 940 950 960 pF1KSD DVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPL 820 830 840 850 860 870 970 980 990 1000 1010 1020 pF1KSD YSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMV 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KSD YLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIP 940 950 960 970 980 990 1090 1100 1110 1120 1130 pF1KSD REDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1000 1010 1020 1030 1040 1050 >>XP_005268901 (OMIM: 600536,613204) PREDICTED: integrin (1068 aa) initn: 6142 init1: 6142 opt: 6142 Z-score: 6839.9 bits: 1277.4 E(85289): 0 Smith-Waterman score: 6832; 95.9% identity (95.9% similar) in 1068 aa overlap (114-1137:1-1068) 90 100 110 120 130 140 pF1KSD QANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHR :::::::::::::::::::::::::::::: XP_005 MQKESKENQWLGVSVRSQGPGGKIVTCAHR 10 20 30 150 160 170 180 190 200 pF1KSD YEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAA 40 50 60 70 80 90 210 220 pF1KSD AFSPDSHYLLFGAPGTYNWKG--------------------------------------- ::::::::::::::::::::: XP_005 AFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPA 100 110 120 130 140 150 230 240 250 260 270 pF1KSD -----LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEEL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEEL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD SFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD GAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDI 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD AVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD GSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYS 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD PTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQ 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD ENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGE 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD DKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPA 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD QPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQ 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD VTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLF 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD FSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPM 760 770 780 790 800 810 880 890 900 910 920 930 pF1KSD QVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSS 820 830 840 850 860 870 940 950 960 970 980 990 pF1KSD AEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVR 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KSD ANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KSD WKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILA 1000 1010 1020 1030 1040 1050 1120 1130 pF1KSD ADGHPELGPDGHPGPGTA :::::::::::::::::: XP_005 ADGHPELGPDGHPGPGTA 1060 1137 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:25:19 2016 done: Thu Nov 3 08:25:21 2016 Total Scan time: 11.850 Total Display time: 0.480 Function used was FASTA [36.3.4 Apr, 2011]