FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0061, 1098 aa
1>>>pF1KSDB0061 1098 - 1098 aa - 1098 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3617+/-0.000597; mu= -5.9591+/- 0.037
mean_var=411.2754+/-88.740, 0's: 0 Z-trim(116.7): 252 B-trim: 38 in 1/54
Lambda= 0.063242
statistics sampled from 27868 (28134) to 27868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.33), width: 16
Scan time: 14.960
The best scores are: opt bits E(85289)
NP_036467 (OMIM: 601480) unconventional myosin-If (1098) 7388 690.0 2e-197
XP_016882310 (OMIM: 601480) PREDICTED: unconventio (1094) 7346 686.2 2.8e-196
XP_011526328 (OMIM: 601480) PREDICTED: unconventio (1090) 5836 548.4 8.5e-155
NP_004989 (OMIM: 601479,614131) unconventional myo (1108) 5358 504.8 1.2e-141
XP_011526326 (OMIM: 601480) PREDICTED: unconventio (1119) 3997 380.6 2.8e-104
XP_011526330 (OMIM: 601480) PREDICTED: unconventio ( 573) 3369 323.0 3.1e-87
XP_011526329 (OMIM: 601480) PREDICTED: unconventio (1074) 3369 323.3 4.8e-87
XP_011526327 (OMIM: 601480) PREDICTED: unconventio (1115) 3182 306.3 6.7e-82
NP_001094891 (OMIM: 614636) unconventional myosin- (1022) 2004 198.7 1.4e-49
XP_016874696 (OMIM: 614636) PREDICTED: unconventio (1027) 2004 198.7 1.4e-49
XP_011536525 (OMIM: 614636) PREDICTED: unconventio (1044) 1790 179.2 1.1e-43
NP_001120651 (OMIM: 276900,276903,600060,601317) u (1178) 1639 165.5 1.7e-39
XP_016873276 (OMIM: 276900,276903,600060,601317) P (1451) 1639 165.6 2e-39
XP_016873275 (OMIM: 276900,276903,600060,601317) P (2154) 1639 165.7 2.6e-39
NP_001120652 (OMIM: 276900,276903,600060,601317) u (2175) 1639 165.7 2.6e-39
XP_016873273 (OMIM: 276900,276903,600060,601317) P (2206) 1639 165.7 2.6e-39
XP_016873277 (OMIM: 276900,276903,600060,601317) P (2207) 1639 165.7 2.6e-39
NP_000251 (OMIM: 276900,276903,600060,601317) unco (2215) 1639 165.7 2.6e-39
XP_016873272 (OMIM: 276900,276903,600060,601317) P (2219) 1639 165.7 2.6e-39
XP_016873271 (OMIM: 276900,276903,600060,601317) P (2220) 1639 165.7 2.6e-39
XP_016873270 (OMIM: 276900,276903,600060,601317) P (2226) 1639 165.7 2.7e-39
XP_011543346 (OMIM: 276900,276903,600060,601317) P (2228) 1639 165.7 2.7e-39
XP_016873269 (OMIM: 276900,276903,600060,601317) P (2245) 1639 165.8 2.7e-39
XP_016873268 (OMIM: 276900,276903,600060,601317) P (2255) 1639 165.8 2.7e-39
XP_016873267 (OMIM: 276900,276903,600060,601317) P (2256) 1639 165.8 2.7e-39
XP_011543348 (OMIM: 276900,276903,600060,601317) P (2258) 1639 165.8 2.7e-39
XP_011543352 (OMIM: 276900,276903,600060,601317) P (2140) 1576 160.0 1.4e-37
NP_036355 (OMIM: 606537) unconventional myosin-Ib (1078) 1461 149.2 1.2e-34
NP_001317166 (OMIM: 606537) unconventional myosin- (1107) 1461 149.2 1.2e-34
NP_001317167 (OMIM: 606537) unconventional myosin- (1107) 1461 149.2 1.2e-34
NP_001123630 (OMIM: 606537) unconventional myosin- (1136) 1461 149.2 1.3e-34
NP_001155291 (OMIM: 606537) unconventional myosin- (1136) 1461 149.2 1.3e-34
XP_005246629 (OMIM: 606537) PREDICTED: unconventio (1136) 1461 149.2 1.3e-34
NP_203693 (OMIM: 606538) unconventional myosin-Ic (1028) 1438 147.1 5.1e-34
NP_001074419 (OMIM: 606538) unconventional myosin- (1044) 1438 147.1 5.1e-34
NP_001074248 (OMIM: 606538) unconventional myosin- (1063) 1438 147.1 5.2e-34
NP_036466 (OMIM: 601481) unconventional myosin-X [ (2058) 1393 143.3 1.4e-32
XP_016877897 (OMIM: 610022) PREDICTED: unconventio (1697) 1356 139.8 1.3e-31
XP_011520083 (OMIM: 610022) PREDICTED: unconventio (1714) 1353 139.5 1.6e-31
NP_061198 (OMIM: 610022) unconventional myosin-Vc (1742) 1353 139.6 1.6e-31
NP_001073996 (OMIM: 606541) unconventional myosin- (2116) 1343 138.7 3.5e-31
XP_006712602 (OMIM: 606541) PREDICTED: unconventio (2142) 1343 138.7 3.5e-31
XP_011509520 (OMIM: 606541) PREDICTED: unconventio (2145) 1343 138.7 3.5e-31
XP_016859658 (OMIM: 606541) PREDICTED: unconventio (2164) 1343 138.7 3.5e-31
XP_011536675 (OMIM: 601478,607841) PREDICTED: unco ( 866) 1331 137.3 3.9e-31
NP_005370 (OMIM: 601478,607841) unconventional myo (1043) 1331 137.3 4.4e-31
NP_001242970 (OMIM: 601478,607841) unconventional (1043) 1331 137.3 4.4e-31
NP_057323 (OMIM: 600316,602666) unconventional myo (3530) 1342 138.8 5.3e-31
XP_016880204 (OMIM: 600316,602666) PREDICTED: unco (3531) 1336 138.3 7.8e-31
XP_011522220 (OMIM: 600316,602666) PREDICTED: unco (2117) 1328 137.4 8.9e-31
>>NP_036467 (OMIM: 601480) unconventional myosin-If [Hom (1098 aa)
initn: 7388 init1: 7388 opt: 7388 Z-score: 3665.4 bits: 690.0 E(85289): 2e-197
Smith-Waterman score: 7388; 99.9% identity (99.9% similar) in 1098 aa overlap (1-1098:1-1098)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK
1030 1040 1050 1060 1070 1080
1090
pF1KSD GRLHGQEGLFPGNYVEKI
::::::::::::::::::
NP_036 GRLHGQEGLFPGNYVEKI
1090
>>XP_016882310 (OMIM: 601480) PREDICTED: unconventional (1094 aa)
initn: 5646 init1: 5646 opt: 7346 Z-score: 3644.7 bits: 686.2 E(85289): 2.8e-196
Smith-Waterman score: 7346; 99.5% identity (99.5% similar) in 1098 aa overlap (1-1098:1-1094)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 TYQVDGTDDRSDFGETL----VIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK
1020 1030 1040 1050 1060 1070
1090
pF1KSD GRLHGQEGLFPGNYVEKI
::::::::::::::::::
XP_016 GRLHGQEGLFPGNYVEKI
1080 1090
>>XP_011526328 (OMIM: 601480) PREDICTED: unconventional (1090 aa)
initn: 5956 init1: 3182 opt: 5836 Z-score: 2900.1 bits: 548.4 E(85289): 8.5e-155
Smith-Waterman score: 6861; 93.1% identity (94.0% similar) in 1119 aa overlap (1-1098:1-1090)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
::: ::::::::::::::::::::::::::::
XP_011 AEQ-----------------------------SPPGIMSVLDDVCATMHATGGGADQTLL
430 440 450
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
520 530 540 550 560 570
610 620 630
pF1KSD V------------KHQVEYLGLKENIRVRRAGFAYRRQFAKFLQ---------RYAILTP
. :: . : . . .. : : .. .. :::::::
XP_011 TGDSPPRGDSAYPPHQSQAPGGIPGPEGEHQGAQSRLRLPPPVRQIPAEPSALRYAILTP
580 590 600 610 620 630
640 650 660 670 680 690
pF1KSD ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
640 650 660 670 680 690
700 710 720 730 740 750
pF1KSD IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
700 710 720 730 740 750
760 770 780 790 800 810
pF1KSD ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
760 770 780 790 800 810
820 830 840 850 860 870
pF1KSD RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
820 830 840 850 860 870
880 890 900 910 920 930
pF1KSD KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
880 890 900 910 920 930
940 950 960 970 980 990
pF1KSD QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
940 950 960 970 980 990
1000 1010 1020 1030 1040 1050
pF1KSD PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
1000 1010 1020 1030 1040 1050
1060 1070 1080 1090
pF1KSD LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
:::::::::::::::::::::::::::::::::::::::
XP_011 LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
1060 1070 1080 1090
>>NP_004989 (OMIM: 601479,614131) unconventional myosin- (1108 aa)
initn: 5332 init1: 4731 opt: 5358 Z-score: 2664.3 bits: 504.8 E(85289): 1.2e-141
Smith-Waterman score: 5362; 71.6% identity (87.6% similar) in 1116 aa overlap (1-1098:1-1108)
10 20 30 40 50
pF1KSD MGSK--ERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVN
:::: ..::::::::.::::::::: .:::..:. ::.::.:::::::::::::::::
NP_004 MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD PFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTV
:::::::: ..::..::::::::::::::::.:::::::.:: :::::::::::::::::
NP_004 PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD AAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSR
::::::.:::.::::: ::::::::::::::::::::::::::::::::::::::::::
NP_004 AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD GGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQ
:::::::::::::::::::::.: .::.:::.:::.:::: ::...::. . ::::::.
NP_004 GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVE
: .:.:: ::: .: ::: ::.:::: : ::::.:::::::::::: : :::: ::
NP_004 SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD SVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLY
: ..::::::::::.. ::.::::::.:::.:::.::::.:::::::: ::::::::.:.
NP_004 SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD ARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT
::.:::::..::.::.: .:::.:::::::::::::::::::::::::::::::::::::
NP_004 ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD LKAEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT
:::::::::: :::::::.:::::.::::::::..::::::.::::::::::.: :::::
NP_004 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD LLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA
:::::: .:.:::::::. ::.:::::::::::..::::::::::: :::::::.::
NP_004 LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD FLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEE
:.. ::::.:..::::::.::::::::::::::.:::.:::::::::::::::.::::::
NP_004 FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD NRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLR
.:::::::::::::::::::::.:::: : :::::::::: ::: :.:.:.::: :::.
NP_004 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD AVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMRE
.:::. ::.:.: .:::.: :::::::::.::::.::.::.:::.::. :: .:: .:::
NP_004 SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD EASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPI
:::..::::::::::::::::.:::.:.::.:::.::.::::..::::.::::::::: .
NP_004 EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD KRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDA
::::.:::::.:.:::::::.::.:: : ::::.:..:. . .::::: :::.:::.:.
NP_004 KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD ADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWG---GGGTRSVTFS
::.:::::::::.::: ::.:: :.. ::: ::.::....:::.:: .::.:.: :
NP_004 YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD RGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRS----SQAPTRAAPAPPR
.::::::::: ....: ::.: ::::.:.:::.. ... : .. :.:::: ::
NP_004 QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPP-
910 920 930 940 950
960 970 980 990 1000
pF1KSD GMDRNGV------P-PSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHN
:. .::: : : : :. . . ::: : . .: : : :
NP_004 GYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPL--PRQQSTSSDRVSQTPES---
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KSD TEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHG--PRCRALYQYVGQDVDELSF
.::.::::: ::..:. . .:: :. :::::::. . :.:.::: : .::.:::::
NP_004 LDFLKVPDQGAAGVRRQTT--SRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSF
1020 1030 1040 1050 1060 1070
1070 1080 1090
pF1KSD NVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
:.:..:.:. ::::::: :::.:..::::.::: ::
NP_004 NANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI
1080 1090 1100
>>XP_011526326 (OMIM: 601480) PREDICTED: unconventional (1119 aa)
initn: 7165 init1: 3997 opt: 3997 Z-score: 1993.2 bits: 380.6 E(85289): 2.8e-104
Smith-Waterman score: 7123; 95.6% identity (96.5% similar) in 1119 aa overlap (1-1098:1-1119)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
550 560 570 580 590 600
610 620 630
pF1KSD V------------KHQVEYLGLKENIRVRRAGFAYRRQFAKFLQ---------RYAILTP
. :: . : . . .. : : .. .. :::::::
XP_011 TGDSPPRGDSAYPPHQSQAPGGIPGPEGEHQGAQSRLRLPPPVRQIPAEPSALRYAILTP
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090
pF1KSD LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
:::::::::::::::::::::::::::::::::::::::
XP_011 LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
1090 1100 1110
>>XP_011526330 (OMIM: 601480) PREDICTED: unconventional (573 aa)
initn: 3369 init1: 3369 opt: 3369 Z-score: 1687.3 bits: 323.0 E(85289): 3.1e-87
Smith-Waterman score: 3369; 99.8% identity (99.8% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::
XP_011 QKLQAAVGTHEHFNSWSAGFVIHHYAGKGLPPDALPREAGWRQEGAPQHRRLQDQETSQR
490 500 510 520 530 540
>>XP_011526329 (OMIM: 601480) PREDICTED: unconventional (1074 aa)
initn: 6537 init1: 3369 opt: 3369 Z-score: 1683.7 bits: 323.3 E(85289): 4.8e-87
Smith-Waterman score: 6468; 90.2% identity (92.7% similar) in 1099 aa overlap (1-1098:1-1074)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
:::::::::::::::::::::::::::: :. :.: . .. . :
XP_011 QKLQAAVGTHEHFNSWSAGFVIHHYAGK------GLPP---DALPREAGWRQEGAPQH--
490 500 510 520
550 560 570 580 590
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLM-RCTPHYIRCIKPNETKRPRDWEEN
: : : . . ::. .... . : : . .:. . .... :
XP_011 RRL----QDQETSQRPGGHTDEVHTPLHPLHQTQRDQEAPR----LGGEQSQAPGGIPGP
530 540 550 560 570 580
600 610 620 630 640 650
pF1KSD RVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRA
. .:: : . :.: . . :::::::::::::::::::::::::::
XP_011 EGEHQ----GAQS--RLRLPPPVRQIPAEPSALRYAILTPETWPRWRGDERQGVQHLLRA
590 600 610 620 630
660 670 680 690 700 710
pF1KSD VNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREE
640 650 660 670 680 690
720 730 740 750 760 770
pF1KSD ASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIK
700 710 720 730 740 750
780 790 800 810 820 830
pF1KSD RDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAA
760 770 780 790 800 810
840 850 860 870 880 890
pF1KSD DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFG
820 830 840 850 860 870
900 910 920 930 940 950
pF1KSD DLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVP
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KSD PSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQ
940 950 960 970 980 990
1020 1030 1040 1050 1060 1070
pF1KSD RKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWW
1000 1010 1020 1030 1040 1050
1080 1090
pF1KSD KGRLHGQEGLFPGNYVEKI
:::::::::::::::::::
XP_011 KGRLHGQEGLFPGNYVEKI
1060 1070
>>XP_011526327 (OMIM: 601480) PREDICTED: unconventional (1115 aa)
initn: 5423 init1: 3182 opt: 3182 Z-score: 1591.3 bits: 306.3 E(85289): 6.7e-82
Smith-Waterman score: 7081; 95.3% identity (96.2% similar) in 1119 aa overlap (1-1098:1-1115)
10 20 30 40 50 60
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 TYQVDGTDDRSDFGETL----VIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
250 260 270 280 290
310 320 330 340 350 360
pF1KSD DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD AEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
540 550 560 570 580 590
610 620 630
pF1KSD V------------KHQVEYLGLKENIRVRRAGFAYRRQFAKFLQ---------RYAILTP
. :: . : . . .. : : .. .. :::::::
XP_011 TGDSPPRGDSAYPPHQSQAPGGIPGPEGEHQGAQSRLRLPPPVRQIPAEPSALRYAILTP
600 610 620 630 640 650
640 650 660 670 680 690
pF1KSD ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFART
660 670 680 690 700 710
700 710 720 730 740 750
pF1KSD IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKR
720 730 740 750 760 770
760 770 780 790 800 810
pF1KSD ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQAL
780 790 800 810 820 830
820 830 840 850 860 870
pF1KSD RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRV
840 850 860 870 880 890
880 890 900 910 920 930
pF1KSD KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKEGWGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSS
900 910 920 930 940 950
940 950 960 970 980 990
pF1KSD QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARP
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KSD PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEHNTEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDE
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090
pF1KSD LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
:::::::::::::::::::::::::::::::::::::::
XP_011 LSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI
1080 1090 1100 1110
>>NP_001094891 (OMIM: 614636) unconventional myosin-Ih [ (1022 aa)
initn: 1618 init1: 919 opt: 2004 Z-score: 1010.9 bits: 198.7 E(85289): 1.4e-49
Smith-Waterman score: 2006; 42.6% identity (73.0% similar) in 760 aa overlap (18-750:12-760)
10 20 30 40 50
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNP
::.:.::: : :.:.. :::::: .. :.::::..:.::::
NP_001 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNP
10 20 30 40 50
60 70 80 90 100 110
pF1KSD FKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVA
.... .: ...::::. .: :::.::..:: :: : . .:. ..:::::::::: :
NP_001 YQELGIYTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD AKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRG
.: :. :.. . ...: ..: .: :::.:::::::.:.::.::::::::..:::.
NP_001 SKKILEYFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD GEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMT-PDYYYYLNQ
: : ::.: ..:.::::::.:::.::::::.:::: :. .:. . ::: :. : ::.:
NP_001 GIPVGGHIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNY-ARV
. . .. .:..:. . .:..:: . . . .. ..:..::::::.: :: . : .
NP_001 GHCAKESSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD ESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGL
.. . . : :::. . : : :: ::.... .: . :..: ..:.:::.::..
NP_001 PDTHEIKWIAKLLGVHPSVLLEALTHRKIEAK----TEEVICPLTLELSVYARDAMAKAV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD YARLFDFLVEAINRAMQKPQ--EEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFI
:.: : .::. :: .. . . .. ::.:::::::.:.::::::::::. ::::::..:
NP_001 YGRTFTWLVNKINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD ELTLKAEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGA
: :::::: :: . ::.: ::.:::::..:::.:.. . ::.:.::. : : ..
NP_001 ERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHK--GIISILDEECIR---PGPAT
420 430 440 450 460
480 490 500 510 520
pF1KSD DQTLLQKLQAAVGTHEHFNSWS-AG-----------FVIHHYAGKVSYDVSGFCERNRDV
: ..:.::. :: : ::.. . :: : . ::::.:.: ..:: :.: :.
NP_001 DLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KSD LFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIR
:. : :.. :.. .:: : . ... :: :.:...:.. ..:. ::. : :::
NP_001 LYRHLKEVLCKSKNIILRECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIR
530 540 550 560 570 580
590 600 610 620 630 640
pF1KSD CIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWP
:::::. :.: ... ..::..:::: :..:::::::::::.. .::::: : :.:::
NP_001 CIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWP
590 600 610 620 630 640
650 660 670 680 690 700
pF1KSD RWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKA
.:.: .::..:.. ....:..:..:.::.:.. :..:: :.. : . .. :: .
NP_001 HWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQAT
650 660 670 680 690 700
710 720 730 740 750
pF1KSD WRRHVAVRKYEEMREEASNI------LLNKK--ERRRNSIN--RNFVGDYLGLEERPELR
..: .. :.: . :. : .. : .: .::. .. :.:. ... ...:
NP_001 YKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFIS-RNKPLCP
710 720 730 740 750 760
760 770 780 790 800 810
pF1KSD QFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK
NP_001 DNEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGI
770 780 790 800 810 820
>>XP_016874696 (OMIM: 614636) PREDICTED: unconventional (1027 aa)
initn: 1618 init1: 919 opt: 2004 Z-score: 1010.9 bits: 198.7 E(85289): 1.4e-49
Smith-Waterman score: 2006; 42.6% identity (73.0% similar) in 760 aa overlap (18-750:12-760)
10 20 30 40 50
pF1KSD MGSKERFHWQSHNVKQSGVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNP
::.:.::: : :.:.. :::::: .. :.::::..:.::::
XP_016 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNP
10 20 30 40 50
60 70 80 90 100 110
pF1KSD FKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVA
.... .: ...::::. .: :::.::..:: :: : . .:. ..:::::::::: :
XP_016 YQELGIYTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD AKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRG
.: :. :.. . ...: ..: .: :::.:::::::.:.::.::::::::..:::.
XP_016 SKKILEYFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD GEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMT-PDYYYYLNQ
: : ::.: ..:.::::::.:::.::::::.:::: :. .:. . ::: :. : ::.:
XP_016 GIPVGGHIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNY-ARV
. . .. .:..:. . .:..:: . . . .. ..:..::::::.: :: . : .
XP_016 GHCAKESSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD ESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGL
.. . . : :::. . : : :: ::.... .: . :..: ..:.:::.::..
XP_016 PDTHEIKWIAKLLGVHPSVLLEALTHRKIEAK----TEEVICPLTLELSVYARDAMAKAV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD YARLFDFLVEAINRAMQKPQ--EEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFI
:.: : .::. :: .. . . .. ::.:::::::.:.::::::::::. ::::::..:
XP_016 YGRTFTWLVNKINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD ELTLKAEQEEYVQAGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGA
: :::::: :: . ::.: ::.:::::..:::.:.. . ::.:.::. : : ..
XP_016 ERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHK--GIISILDEECIR---PGPAT
420 430 440 450 460
480 490 500 510 520
pF1KSD DQTLLQKLQAAVGTHEHFNSWS-AG-----------FVIHHYAGKVSYDVSGFCERNRDV
: ..:.::. :: : ::.. . :: : . ::::.:.: ..:: :.: :.
XP_016 DLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KSD LFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIR
:. : :.. :.. .:: : . ... :: :.:...:.. ..:. ::. : :::
XP_016 LYRHLKEVLCKSKNIILRECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIR
530 540 550 560 570 580
590 600 610 620 630 640
pF1KSD CIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWP
:::::. :.: ... ..::..:::: :..:::::::::::.. .::::: : :.:::
XP_016 CIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWP
590 600 610 620 630 640
650 660 670 680 690 700
pF1KSD RWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKA
.:.: .::..:.. ....:..:..:.::.:.. :..:: :.. : . .. :: .
XP_016 HWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQAT
650 660 670 680 690 700
710 720 730 740 750
pF1KSD WRRHVAVRKYEEMREEASNI------LLNKK--ERRRNSIN--RNFVGDYLGLEERPELR
..: .. :.: . :. : .. : .: .::. .. :.:. ... ...:
XP_016 YKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFIS-RNKPLCP
710 720 730 740 750 760
760 770 780 790 800 810
pF1KSD QFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK
XP_016 DNEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGI
770 780 790 800 810 820
1098 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:26:59 2016 done: Thu Nov 3 08:27:01 2016
Total Scan time: 14.960 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]