FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB0234, 1203 aa 1>>>pF1KSDB0234 1203 - 1203 aa - 1203 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7867+/-0.000474; mu= 10.0890+/- 0.030 mean_var=119.5162+/-23.960, 0's: 0 Z-trim(112.7): 409 B-trim: 122 in 1/51 Lambda= 0.117317 statistics sampled from 21265 (21686) to 21265 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.254), width: 16 Scan time: 14.710 The best scores are: opt bits E(85289) NP_065136 (OMIM: 603581) protocadherin-9 isoform 2 (1203) 7902 1349.7 0 NP_001305301 (OMIM: 603581) protocadherin-9 isofor (1195) 7589 1296.7 0 XP_011533401 (OMIM: 603581) PREDICTED: protocadher (1054) 6564 1123.2 0 NP_001305302 (OMIM: 603581) protocadherin-9 isofor (1161) 6560 1122.5 0 XP_016876109 (OMIM: 603581) PREDICTED: protocadher (1066) 6551 1121.0 0 NP_982354 (OMIM: 603581) protocadherin-9 isoform 1 (1237) 6551 1121.0 0 XP_016876108 (OMIM: 603581) PREDICTED: protocadher (1237) 6551 1121.0 0 XP_005266465 (OMIM: 603581) PREDICTED: protocadher (1019) 6543 1119.6 0 XP_016876110 (OMIM: 603581) PREDICTED: protocadher (1019) 6543 1119.6 0 NP_001305303 (OMIM: 603581) protocadherin-9 isofor (1032) 6543 1119.6 0 XP_016884908 (OMIM: 300246) PREDICTED: protocadher (1308) 4379 753.4 2.2e-216 XP_016885570 (OMIM: 400022) PREDICTED: protocadher (1329) 4356 749.5 3.3e-215 XP_016885569 (OMIM: 400022) PREDICTED: protocadher (1329) 4356 749.5 3.3e-215 XP_016885568 (OMIM: 400022) PREDICTED: protocadher (1329) 4356 749.5 3.3e-215 NP_116755 (OMIM: 400022) protocadherin-11 Y-linked (1340) 4356 749.5 3.3e-215 NP_001161834 (OMIM: 300246) protocadherin-11 X-lin (1310) 4294 739.0 4.6e-212 XP_016884909 (OMIM: 300246) PREDICTED: protocadher (1339) 4294 739.0 4.7e-212 XP_016884911 (OMIM: 300246) PREDICTED: protocadher (1025) 3967 683.6 1.7e-195 XP_011529217 (OMIM: 300246) PREDICTED: protocadher (1054) 3967 683.6 1.7e-195 XP_011529218 (OMIM: 300246) PREDICTED: protocadher (1054) 3967 683.6 1.7e-195 NP_001161833 (OMIM: 300246) protocadherin-11 X-lin (1065) 3964 683.1 2.5e-195 XP_016884910 (OMIM: 300246) PREDICTED: protocadher (1076) 3964 683.1 2.5e-195 NP_001161835 (OMIM: 300246) protocadherin-11 X-lin (1329) 3964 683.1 3.1e-195 NP_116751 (OMIM: 300246) protocadherin-11 X-linked (1337) 3964 683.1 3.1e-195 NP_001161832 (OMIM: 300246) protocadherin-11 X-lin (1339) 3964 683.1 3.1e-195 XP_016884905 (OMIM: 300246) PREDICTED: protocadher (1345) 3964 683.1 3.1e-195 XP_011529216 (OMIM: 300246) PREDICTED: protocadher (1347) 3964 683.1 3.1e-195 NP_116750 (OMIM: 300246) protocadherin-11 X-linked (1347) 3964 683.1 3.1e-195 XP_011529215 (OMIM: 300246) PREDICTED: protocadher (1358) 3964 683.2 3.1e-195 XP_016884907 (OMIM: 300246) PREDICTED: protocadher (1366) 3964 683.2 3.1e-195 XP_011529214 (OMIM: 300246) PREDICTED: protocadher (1368) 3964 683.2 3.1e-195 XP_011529212 (OMIM: 300246) PREDICTED: protocadher (1376) 3964 683.2 3.2e-195 XP_011529213 (OMIM: 300246) PREDICTED: protocadher (1376) 3964 683.2 3.2e-195 XP_016884906 (OMIM: 300246) PREDICTED: protocadher (1376) 3964 683.2 3.2e-195 NP_001265548 (OMIM: 400022) protocadherin-11 Y-lin (1037) 3942 679.4 3.2e-194 XP_016885571 (OMIM: 400022) PREDICTED: protocadher (1037) 3942 679.4 3.2e-194 NP_116753 (OMIM: 400022) protocadherin-11 Y-linked (1037) 3942 679.4 3.2e-194 NP_116754 (OMIM: 400022) protocadherin-11 Y-linked (1048) 3942 679.4 3.3e-194 XP_016885572 (OMIM: 400022) PREDICTED: protocadher ( 956) 3795 654.5 9.3e-187 XP_016876197 (OMIM: 614449) PREDICTED: protocadher ( 951) 2086 365.2 1.1e-99 NP_073754 (OMIM: 614449) protocadherin-20 precurso ( 951) 2086 365.2 1.1e-99 XP_005248220 (OMIM: 602988) PREDICTED: protocadher (1275) 1687 297.8 3e-79 XP_016863751 (OMIM: 602988) PREDICTED: protocadher (1277) 1681 296.7 6.2e-79 XP_005248221 (OMIM: 602988) PREDICTED: protocadher (1267) 1678 296.2 8.7e-79 XP_011512145 (OMIM: 602988) PREDICTED: protocadher (1276) 1594 282.0 1.7e-74 XP_011512144 (OMIM: 602988) PREDICTED: protocadher (1296) 1510 267.8 3.2e-70 XP_016863757 (OMIM: 602988) PREDICTED: protocadher (1182) 1509 267.6 3.3e-70 XP_016863758 (OMIM: 602988) PREDICTED: protocadher (1182) 1509 267.6 3.3e-70 XP_016863752 (OMIM: 602988) PREDICTED: protocadher (1200) 1508 267.5 3.8e-70 XP_016863753 (OMIM: 602988) PREDICTED: protocadher (1200) 1508 267.5 3.8e-70 >>NP_065136 (OMIM: 603581) protocadherin-9 isoform 2 pre (1203 aa) initn: 7902 init1: 7902 opt: 7902 Z-score: 7229.0 bits: 1349.7 E(85289): 0 Smith-Waterman score: 7902; 100.0% identity (100.0% similar) in 1203 aa overlap (1-1203:1-1203) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1150 1160 1170 1180 1190 1200 pF1KSD HQL ::: NP_065 HQL >>NP_001305301 (OMIM: 603581) protocadherin-9 isoform 3 (1195 aa) initn: 7598 init1: 6543 opt: 7589 Z-score: 6942.8 bits: 1296.7 E(85289): 0 Smith-Waterman score: 7589; 97.0% identity (98.1% similar) in 1204 aa overlap (1-1203:1-1195) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-SQRRVTF :::::::::::::::::::::::::::::::::::::::::::::::::::: ... . NP_001 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD HLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS ..: :. :..:. .: . :: .::::::::::::::::::::::::: NP_001 NIPVTPQKCPSSTGFHIQE-----NEESH----YEPQDEFYDQASPDKRTEADGNSDPNS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KSD DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKL 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KSD VNGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPK 1140 1150 1160 1170 1180 1190 1200 pF1KSD EHQL :::: NP_001 EHQL >>XP_011533401 (OMIM: 603581) PREDICTED: protocadherin-9 (1054 aa) initn: 7060 init1: 6553 opt: 6564 Z-score: 6006.1 bits: 1123.2 E(85289): 0 Smith-Waterman score: 6564; 98.4% identity (99.4% similar) in 1032 aa overlap (1-1031:1-1030) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH ::::::::::::::::::::::::::::::::::::::::::::::::::::... . : XP_011 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQGKQTLIF- 970 980 990 1000 1010 1030 1040 1050 1060 1070 pF1KSD LPDGSQE-SCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS :.:... .: . XP_011 -PSGAEDFQCHNVRIIFPNFPILFVMSHEYVSEKST 1020 1030 1040 1050 >>NP_001305302 (OMIM: 603581) protocadherin-9 isoform 4 (1161 aa) initn: 7014 init1: 6549 opt: 6560 Z-score: 6001.7 bits: 1122.5 E(85289): 0 Smith-Waterman score: 7516; 96.5% identity (96.5% similar) in 1203 aa overlap (1-1203:1-1161) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-------- 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD :::::::::::::::::::::::::: NP_001 ----------------------------------PQDEFYDQASPDKRTEADGNSDPNSD 1020 1030 1090 1100 1110 1120 1130 1140 pF1KSD GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KSD NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1100 1110 1120 1130 1140 1150 pF1KSD HQL ::: NP_001 HQL 1160 >>XP_016876109 (OMIM: 603581) PREDICTED: protocadherin-9 (1066 aa) initn: 6543 init1: 6543 opt: 6551 Z-score: 5994.1 bits: 1121.0 E(85289): 0 Smith-Waterman score: 6551; 97.9% identity (98.9% similar) in 1039 aa overlap (1-1038:1-1039) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-SQRRVTF :::::::::::::::::::::::::::::::::::::::::::::::::::: ... . XP_016 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD HLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS ..: :. :..:. .: XP_016 NIPVTPQKCPSSTGFHIQENEESHYEILQSKGVYSYQHVTIKCKQC 1030 1040 1050 1060 >>NP_982354 (OMIM: 603581) protocadherin-9 isoform 1 pre (1237 aa) initn: 6543 init1: 6543 opt: 6551 Z-score: 5993.0 bits: 1121.0 E(85289): 0 Smith-Waterman score: 7812; 97.2% identity (97.2% similar) in 1235 aa overlap (1-1201:1-1235) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 970 980 990 1000 1010 1020 1020 1030 1040 pF1KSD --------------------------SQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI :::::::::::::::::::::::::::::::::: NP_982 NIPVTPQKCPSSTGFHIQENEESHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 pF1KSD NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL ::::::::::::::::::::::::::::::::::: NP_982 NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL 1210 1220 1230 >>XP_016876108 (OMIM: 603581) PREDICTED: protocadherin-9 (1237 aa) initn: 6543 init1: 6543 opt: 6551 Z-score: 5993.0 bits: 1121.0 E(85289): 0 Smith-Waterman score: 7812; 97.2% identity (97.2% similar) in 1235 aa overlap (1-1201:1-1235) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-------- :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 970 980 990 1000 1010 1020 1020 1030 1040 pF1KSD --------------------------SQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI :::::::::::::::::::::::::::::::::: XP_016 NIPVTPQKCPSSTGFHIQENEESHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 pF1KSD NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL ::::::::::::::::::::::::::::::::::: XP_016 NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL 1210 1220 1230 >>XP_005266465 (OMIM: 603581) PREDICTED: protocadherin-9 (1019 aa) initn: 6543 init1: 6543 opt: 6543 Z-score: 5987.1 bits: 1119.6 E(85289): 0 Smith-Waterman score: 6543; 100.0% identity (100.0% similar) in 1012 aa overlap (1-1012:1-1012) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQFPSNGKR 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD >>XP_016876110 (OMIM: 603581) PREDICTED: protocadherin-9 (1019 aa) initn: 6543 init1: 6543 opt: 6543 Z-score: 5987.1 bits: 1119.6 E(85289): 0 Smith-Waterman score: 6543; 100.0% identity (100.0% similar) in 1012 aa overlap (1-1012:1-1012) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQFPSNGKR 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD >>NP_001305303 (OMIM: 603581) protocadherin-9 isoform 5 (1032 aa) initn: 6543 init1: 6543 opt: 6543 Z-score: 5987.0 bits: 1119.6 E(85289): 0 Smith-Waterman score: 6543; 100.0% identity (100.0% similar) in 1012 aa overlap (1-1012:1-1012) 10 20 30 40 50 60 pF1KSD MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQVNEHFYWS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD NP_001 ISTAYKCPVNQY 1030 1203 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:31:33 2016 done: Thu Nov 3 08:31:35 2016 Total Scan time: 14.710 Total Display time: 0.510 Function used was FASTA [36.3.4 Apr, 2011]