Result of FASTA (omim) for
pF1KSDB1316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB1316, 862 aa
1>>>pF1KSDB1316 862 - 862 aa - 862 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4917+/-0.000407; mu= 9.8293+/- 0.025
mean_var=116.3981+/-24.074, 0's: 0 Z-trim(114.9): 180 B-trim: 0 in 0/53
Lambda= 0.118878
statistics sampled from 24761 (24960) to 24761 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.293), width: 16
Scan time: 13.500
The best scores are: opt bits E(85289)
XP_011516435 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_016869684 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516431 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516430 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
NP_006369 (OMIM: 601866) semaphorin-4D isoform 1 p ( 862) 5793 1005.3 0
XP_016869683 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516427 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_016869682 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516425 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516426 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516433 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516432 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_016869686 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_016869685 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516436 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_016869687 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_005251711 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
XP_011516429 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 5793 1005.3 0
NP_001135759 (OMIM: 601866) semaphorin-4D isoform ( 738) 3748 654.5 5.1e-187
XP_016869688 (OMIM: 601866) PREDICTED: semaphorin- ( 534) 3235 566.5 1.2e-160
XP_011509682 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
NP_060259 (OMIM: 604462) semaphorin-4C precursor [ ( 833) 1700 303.3 3.1e-81
XP_011509680 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
XP_011509684 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
XP_011509681 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
XP_011509685 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
XP_011509683 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 1700 303.3 3.1e-81
XP_016859882 (OMIM: 604462) PREDICTED: semaphorin- ( 875) 1700 303.3 3.2e-81
NP_064595 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1491 267.4 1.9e-70
NP_945119 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1491 267.4 1.9e-70
NP_001310960 (OMIM: 617029) semaphorin-4B isoform ( 890) 1491 267.5 2e-70
NP_001310961 (OMIM: 617029) semaphorin-4B isoform ( 602) 1431 257.1 1.8e-67
NP_001310963 (OMIM: 617029) semaphorin-4B isoform ( 847) 1433 257.5 1.9e-67
XP_006712669 (OMIM: 604462) PREDICTED: semaphorin- ( 495) 1414 254.2 1.1e-66
XP_011530777 (OMIM: 603706) PREDICTED: semaphorin- ( 624) 1374 247.3 1.6e-64
NP_004254 (OMIM: 603706) semaphorin-4F isoform 1 p ( 770) 1370 246.7 3.1e-64
XP_016859883 (OMIM: 604462) PREDICTED: semaphorin- ( 692) 1369 246.5 3.2e-64
XP_011530778 (OMIM: 603706) PREDICTED: semaphorin- ( 600) 1361 245.1 7.3e-64
XP_011530779 (OMIM: 603706) PREDICTED: semaphorin- ( 597) 1359 244.8 9.2e-64
NP_001310962 (OMIM: 617029) semaphorin-4B isoform ( 681) 1301 234.8 1e-60
NP_001310959 (OMIM: 617029) semaphorin-4B isoform ( 681) 1301 234.8 1e-60
NP_004627 (OMIM: 601281) semaphorin-3B isoform 1 p ( 749) 1251 226.3 4.2e-58
NP_001276989 (OMIM: 601281) semaphorin-3B isoform ( 749) 1251 226.3 4.2e-58
NP_001005914 (OMIM: 601281) semaphorin-3B isoform ( 748) 1246 225.4 7.7e-58
XP_016867162 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1228 222.3 6.7e-57
XP_011514036 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1228 222.3 6.7e-57
XP_005250168 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1228 222.3 6.7e-57
XP_005250167 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1228 222.3 6.7e-57
NP_006071 (OMIM: 603961,614897) semaphorin-3A prec ( 771) 1228 222.3 6.7e-57
XP_006715902 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1228 222.3 6.7e-57
>>XP_011516435 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_016869684 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_016 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_016 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_011516431 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_011516430 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
>>NP_006369 (OMIM: 601866) semaphorin-4D isoform 1 precu (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_006 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
NP_006 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_016869683 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_016 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_016 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_011516427 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_016869682 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_016 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_016 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_011516425 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
>>XP_011516426 (OMIM: 601866) PREDICTED: semaphorin-4D i (862 aa)
initn: 5793 init1: 5793 opt: 5793 Z-score: 5373.0 bits: 1005.3 E(85289): 0
Smith-Waterman score: 5793; 99.9% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KSD MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SPGLKVPVFYALFTPQLNNVGLSAVCTYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 SPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLIQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQDTITSKVPTDREDSQRIDDLS
790 800 810 820 830 840
850 860
pF1KSD ARDKPFDVKCELKFADSDADGD
::::::::::::::::::::::
XP_011 ARDKPFDVKCELKFADSDADGD
850 860
862 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:34:34 2016 done: Thu Nov 3 08:34:36 2016
Total Scan time: 13.500 Total Display time: 0.360
Function used was FASTA [36.3.4 Apr, 2011]