FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB1483, 1198 aa 1>>>pF1KSDB1483 1198 - 1198 aa - 1198 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5119+/-0.00044; mu= 21.7897+/- 0.027 mean_var=92.9432+/-19.348, 0's: 0 Z-trim(112.0): 197 B-trim: 581 in 1/52 Lambda= 0.133035 statistics sampled from 20450 (20722) to 20450 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.243), width: 16 Scan time: 14.810 The best scores are: opt bits E(85289) NP_001674 (OMIM: 108733,601386) plasma membrane ca (1198) 7854 1519.1 0 XP_016861976 (OMIM: 108733,601386) PREDICTED: plas (1198) 7854 1519.1 0 NP_001317540 (OMIM: 108733,601386) plasma membrane (1154) 7235 1400.2 0 XP_016861979 (OMIM: 108733,601386) PREDICTED: plas (1160) 7235 1400.2 0 XP_005274748 (OMIM: 300014) PREDICTED: plasma memb (1206) 6680 1293.7 0 XP_011529479 (OMIM: 300014) PREDICTED: plasma memb (1248) 6239 1209.1 0 XP_016861973 (OMIM: 108733,601386) PREDICTED: plas (1212) 5906 1145.2 0 XP_016861972 (OMIM: 108733,601386) PREDICTED: plas (1212) 5906 1145.2 0 NP_001001331 (OMIM: 108733,601386) plasma membrane (1243) 5894 1142.9 0 XP_006713238 (OMIM: 108733,601386) PREDICTED: plas (1243) 5894 1142.9 0 XP_016861970 (OMIM: 108733,601386) PREDICTED: plas (1243) 5894 1142.9 0 XP_011532054 (OMIM: 108733,601386) PREDICTED: plas (1243) 5894 1142.9 0 XP_016861971 (OMIM: 108733,601386) PREDICTED: plas (1243) 5894 1142.9 0 XP_005265236 (OMIM: 108733,601386) PREDICTED: plas (1243) 5894 1142.9 0 XP_016861978 (OMIM: 108733,601386) PREDICTED: plas (1168) 5287 1026.4 0 XP_016861977 (OMIM: 108733,601386) PREDICTED: plas (1174) 5287 1026.4 0 XP_016861975 (OMIM: 108733,601386) PREDICTED: plas (1199) 5275 1024.1 0 XP_016861974 (OMIM: 108733,601386) PREDICTED: plas (1205) 5275 1024.1 0 XP_016861981 (OMIM: 108733,601386) PREDICTED: plas (1272) 5275 1024.1 0 NP_001001344 (OMIM: 300014) plasma membrane calciu (1220) 5087 988.0 0 XP_005274747 (OMIM: 300014) PREDICTED: plasma memb (1220) 5087 988.0 0 NP_001673 (OMIM: 108731) plasma membrane calcium-t (1220) 5066 984.0 0 XP_005274746 (OMIM: 300014) PREDICTED: plasma memb (1249) 4680 909.9 0 NP_068768 (OMIM: 300014) plasma membrane calcium-t (1173) 4673 908.5 0 XP_005274749 (OMIM: 300014) PREDICTED: plasma memb (1173) 4673 908.5 0 XP_011529476 (OMIM: 300014) PREDICTED: plasma memb (1262) 4646 903.4 0 XP_016885042 (OMIM: 300014) PREDICTED: plasma memb (1274) 4624 899.1 0 NP_001001323 (OMIM: 108731) plasma membrane calciu (1176) 4547 884.3 0 XP_011536709 (OMIM: 108731) PREDICTED: plasma memb (1249) 4547 884.4 0 NP_001675 (OMIM: 108732) plasma membrane calcium-t (1205) 4543 883.6 0 XP_016874846 (OMIM: 108731) PREDICTED: plasma memb (1213) 4424 860.7 0 NP_001001396 (OMIM: 108732) plasma membrane calciu (1170) 4362 848.8 0 XP_016874848 (OMIM: 108731) PREDICTED: plasma memb (1140) 3943 768.4 0 XP_016874847 (OMIM: 108731) PREDICTED: plasma memb (1184) 3943 768.4 0 XP_016874849 (OMIM: 108731) PREDICTED: plasma memb ( 705) 1905 377.1 2.2e-103 XP_011510988 (OMIM: 169600,604384) PREDICTED: calc ( 671) 452 98.2 1.9e-19 NP_001186114 (OMIM: 169600,604384) calcium-transpo ( 888) 452 98.3 2.4e-19 NP_001001485 (OMIM: 169600,604384) calcium-transpo ( 888) 452 98.3 2.4e-19 NP_001186113 (OMIM: 169600,604384) calcium-transpo ( 903) 452 98.3 2.4e-19 NP_001186108 (OMIM: 169600,604384) calcium-transpo ( 919) 452 98.3 2.4e-19 NP_055197 (OMIM: 169600,604384) calcium-transporti ( 919) 452 98.3 2.4e-19 NP_001186112 (OMIM: 169600,604384) calcium-transpo ( 923) 452 98.3 2.4e-19 XP_005247415 (OMIM: 169600,604384) PREDICTED: calc ( 933) 452 98.3 2.4e-19 NP_001001487 (OMIM: 169600,604384) calcium-transpo ( 939) 452 98.3 2.5e-19 XP_016861653 (OMIM: 169600,604384) PREDICTED: calc ( 939) 452 98.3 2.5e-19 NP_001186111 (OMIM: 169600,604384) calcium-transpo ( 944) 452 98.3 2.5e-19 XP_005247413 (OMIM: 169600,604384) PREDICTED: calc ( 949) 452 98.3 2.5e-19 NP_001001486 (OMIM: 169600,604384) calcium-transpo ( 949) 452 98.3 2.5e-19 XP_005247412 (OMIM: 169600,604384) PREDICTED: calc ( 949) 452 98.3 2.5e-19 NP_001186110 (OMIM: 169600,604384) calcium-transpo ( 953) 452 98.3 2.5e-19 >>NP_001674 (OMIM: 108733,601386) plasma membrane calciu (1198 aa) initn: 7854 init1: 7854 opt: 7854 Z-score: 8144.6 bits: 1519.1 E(85289): 0 Smith-Waterman score: 7854; 100.0% identity (100.0% similar) in 1198 aa overlap (1-1198:1-1198) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KSD DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1150 1160 1170 1180 1190 >>XP_016861976 (OMIM: 108733,601386) PREDICTED: plasma m (1198 aa) initn: 7854 init1: 7854 opt: 7854 Z-score: 8144.6 bits: 1519.1 E(85289): 0 Smith-Waterman score: 7854; 100.0% identity (100.0% similar) in 1198 aa overlap (1-1198:1-1198) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KSD DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1150 1160 1170 1180 1190 >>NP_001317540 (OMIM: 108733,601386) plasma membrane cal (1154 aa) initn: 7229 init1: 7229 opt: 7235 Z-score: 7502.8 bits: 1400.2 E(85289): 0 Smith-Waterman score: 7235; 98.7% identity (99.5% similar) in 1120 aa overlap (1-1118:1-1120) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KSD GQILWFRGLNRIQTQIRVVKAFRSSL-YEG-LEKPESRTSIHNFMAHPEFRIEDSQPHIP ::::::::::::::::.::..:.:. ..: :.. : :: NP_001 GQILWFRGLNRIQTQIEVVNTFKSGASFQGALRRQSSVTSQSQDVANLSSPSRVSLSNAL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD LIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL NP_001 SSPTSLPPAAAGQG 1150 >>XP_016861979 (OMIM: 108733,601386) PREDICTED: plasma m (1160 aa) initn: 7229 init1: 7229 opt: 7235 Z-score: 7502.7 bits: 1400.2 E(85289): 0 Smith-Waterman score: 7235; 98.7% identity (99.5% similar) in 1120 aa overlap (1-1118:1-1120) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KSD GQILWFRGLNRIQTQIRVVKAFRSSL-YEG-LEKPESRTSIHNFMAHPEFRIEDSQPHIP ::::::::::::::::.::..:.:. ..: :.. : :: XP_016 GQILWFRGLNRIQTQIEVVNTFKSGASFQGALRRQSSVTSQSQDVANLSSPSRVSLSNAL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD LIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL XP_016 SSPTSLPPAAAGHPRREGVP 1150 1160 >>XP_005274748 (OMIM: 300014) PREDICTED: plasma membrane (1206 aa) initn: 4807 init1: 4807 opt: 6680 Z-score: 6926.8 bits: 1293.7 E(85289): 0 Smith-Waterman score: 6680; 83.8% identity (94.1% similar) in 1207 aa overlap (1-1198:1-1206) 10 20 30 40 50 pF1KSD MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC ::::.:: .:. : .:. . ..: ::::. :::.::::::.::. ::.:.:::. ..: XP_005 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII :::::::.::: .. :::::.::.::::::::.:::::::::::::::::::::.:::. XP_005 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ::::::: :::: .:.:....::::::::::::::::::::::::::::::::::::::: XP_005 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID :::::::::::::::::.: ::..:.::: .::::::::::::::::::..::.:::::: XP_005 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE :::::::::.::::.:::::::::::::::::::.::::::::::::::::::::::::: XP_005 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD KKDKKAKQQDGAAAMEMQPLKSAEGGDADDR--KKASMHKKEKSVLQGKLTKLAVQIGKA :::::::.::::.:::::::::::::. ..: :::. ::::::::::::::::::::: XP_005 KKDKKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP ::::::::::::::::...::::. . :: :::::::::::::::::::::::::::::: XP_005 GLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::.:.::.: XP_005 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTH 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD YKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDL ::::: ::... : ..::..::.::::::::::::::::::::::::::::.:::::::: XP_005 YKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILN :.:..::: :.::.:::::::::::::::::::..:: .::..:::::::.:::: .::: XP_005 KRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD GAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCI . :: : :::::::.::.:.:::::::::::::.::::: .. ::::::::.....:::: XP_005 SNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGK ::::::::::::::::::::::::::::::::::::::::: :::::.::::::::::: XP_005 AVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD EFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD :::::::::::::::::.::.:::::::::::::::::::::::::: ::::::::::: XP_005 EFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGD 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQ ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: XP_005 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPY ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: XP_005 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPY 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD GRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFN ::.:::::::::::::::::::::.::::::::: .:.:::::::::::::::::::::: XP_005 GRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFN 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD TFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQ ::::::::::::::::::::::::::: ::::::::::::.::::::::::::::::::. XP_005 TFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLS 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD LDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAE .::.::.:.:.:::::::::::::::.:: :::::. :.:. .::: : ::::::: XP_005 TEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAE 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD RELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQP ::::::::::::::::::::::::::::::::::::::::.:::::::: ::: :.: XP_005 RELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTH 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD HIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSS----SPGSPI .::::::::..:. . . :: : :.::.:::::: ::: ..:::::: :::::. XP_005 NIPLIDDTDVDENEE-RLRAPPPPSPNQNNNAIDSGIYLTTHVTKSATSSVFSSSPGSPL 1150 1160 1170 1180 1190 pF1KSD HSLETSL ::.:::: XP_005 HSVETSL 1200 >>XP_011529479 (OMIM: 300014) PREDICTED: plasma membrane (1248 aa) initn: 4505 init1: 4505 opt: 6239 Z-score: 6469.2 bits: 1209.1 E(85289): 0 Smith-Waterman score: 6239; 85.3% identity (95.3% similar) in 1100 aa overlap (1-1095:1-1100) 10 20 30 40 50 pF1KSD MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC ::::.:: .:. : .:. . ..: ::::. :::.::::::.::. ::.:.:::. ..: XP_011 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII :::::::.::: .. :::::.::.::::::::.:::::::::::::::::::::.:::. XP_011 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ::::::: :::: .:.:....::::::::::::::::::::::::::::::::::::::: XP_011 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID :::::::::::::::::.: ::..:.::: .::::::::::::::::::..::.:::::: XP_011 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE :::::::::.::::.:::::::::::::::::::.::::::::::::::::::::::::: XP_011 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD KKDKKAKQQDGAAAMEMQPLKSAEGGDADDR--KKASMHKKEKSVLQGKLTKLAVQIGKA :::::::.::::.:::::::::::::. ..: :::. ::::::::::::::::::::: XP_011 KKDKKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP ::::::::::::::::...::::. . :: :::::::::::::::::::::::::::::: XP_011 GLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::.:.::.: XP_011 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTH 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD YKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDL ::::: ::... : ..::..::.::::::::::::::::::::::::::::.:::::::: XP_011 YKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILN :.:..::: :.::.:::::::::::::::::::..:: .::..:::::::.:::: .::: XP_011 KRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD GAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCI . :: : :::::::.::.:.:::::::::::::.::::: .. ::::::::.....:::: XP_011 SNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCI 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGK ::::::::::::::::::::::::::::::::::::::::: :::::.::::::::::: XP_011 AVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD EFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD :::::::::::::::::.::.:::::::::::::::::::::::::: ::::::::::: XP_011 EFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGD 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQ ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: XP_011 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPY ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: XP_011 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPY 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD GRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFN ::.:::::::::::::::::::::.::::::::: .:.:::::::::::::::::::::: XP_011 GRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFN 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD TFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQ ::::::::::::::::::::::::::: ::::::::::::.::::::::::::::::::. XP_011 TFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLS 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD LDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAE .::.::.:.:.:::::::::::::::.:: :::::. :.:. .::: : ::::::: XP_011 TEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAE 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD RELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQP :::::::::::::::::::: XP_011 RELRRGQILWFRGLNRIQTQPGLCPPLPRNGARLGLRGSLPARGVGLSLHRSCLLWALPG 1090 1100 1110 1120 1130 1140 >>XP_016861973 (OMIM: 108733,601386) PREDICTED: plasma m (1212 aa) initn: 5893 init1: 5893 opt: 5906 Z-score: 6123.9 bits: 1145.2 E(85289): 0 Smith-Waterman score: 7816; 98.8% identity (98.8% similar) in 1212 aa overlap (1-1198:1-1212) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 pF1KSD KK--------------AKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLT :: :::::::::::::::::::::::::::::::::::::::::::: XP_016 KKGKMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD KLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD VQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTEC 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD GLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNEN 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD DILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD EDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQ 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPT 850 860 870 880 890 900 890 900 910 920 930 940 pF1KSD ETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KSD SEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KSD KPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNE 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KSD DVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHP 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KSD EFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS 1150 1160 1170 1180 1190 1200 1190 pF1KSD PGSPIHSLETSL :::::::::::: XP_016 PGSPIHSLETSL 1210 >>XP_016861972 (OMIM: 108733,601386) PREDICTED: plasma m (1212 aa) initn: 5893 init1: 5893 opt: 5906 Z-score: 6123.9 bits: 1145.2 E(85289): 0 Smith-Waterman score: 7816; 98.8% identity (98.8% similar) in 1212 aa overlap (1-1198:1-1212) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 320 330 340 pF1KSD KK--------------AKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLT :: :::::::::::::::::::::::::::::::::::::::::::: XP_016 KKGKMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD KLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD VQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTEC 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD GLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNEN 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD DILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD EDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQ 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPT 850 860 870 880 890 900 890 900 910 920 930 940 pF1KSD ETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KSD SEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KSD KPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNE 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KSD DVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHP 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KSD EFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS 1150 1160 1170 1180 1190 1200 1190 pF1KSD PGSPIHSLETSL :::::::::::: XP_016 PGSPIHSLETSL 1210 >>NP_001001331 (OMIM: 108733,601386) plasma membrane cal (1243 aa) initn: 5893 init1: 5893 opt: 5894 Z-score: 6111.4 bits: 1142.9 E(85289): 0 Smith-Waterman score: 7665; 96.3% identity (96.3% similar) in 1230 aa overlap (14-1198:14-1243) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 pF1KSD KK---------------------------------------------AKQQDGAAAMEMQ :: ::::::::::::: NP_001 KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 310 320 330 340 350 360 320 330 340 350 360 370 pF1KSD PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 370 380 390 400 410 420 380 390 400 410 420 430 pF1KSD FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 430 440 450 460 470 480 440 450 460 470 480 490 pF1KSD VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 490 500 510 520 530 540 500 510 520 530 540 550 pF1KSD AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 550 560 570 580 590 600 560 570 580 590 600 610 pF1KSD TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 610 620 630 640 650 660 620 630 640 650 660 670 pF1KSD IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 670 680 690 700 710 720 680 690 700 710 720 730 pF1KSD QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 730 740 750 760 770 780 740 750 760 770 780 790 pF1KSD IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 790 800 810 820 830 840 800 810 820 830 840 850 pF1KSD GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 850 860 870 880 890 900 860 870 880 890 900 910 pF1KSD QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 910 920 930 940 950 960 920 930 940 950 960 970 pF1KSD YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KSD NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KSD IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KSD IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 pF1KSD SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL ::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1210 1220 1230 1240 >>XP_006713238 (OMIM: 108733,601386) PREDICTED: plasma m (1243 aa) initn: 5893 init1: 5893 opt: 5894 Z-score: 6111.4 bits: 1142.9 E(85289): 0 Smith-Waterman score: 7665; 96.3% identity (96.3% similar) in 1230 aa overlap (14-1198:14-1243) 10 20 30 40 50 60 pF1KSD MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 250 260 270 280 290 300 310 pF1KSD KK---------------------------------------------AKQQDGAAAMEMQ :: ::::::::::::: XP_006 KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 310 320 330 340 350 360 320 330 340 350 360 370 pF1KSD PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 370 380 390 400 410 420 380 390 400 410 420 430 pF1KSD FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 430 440 450 460 470 480 440 450 460 470 480 490 pF1KSD VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 490 500 510 520 530 540 500 510 520 530 540 550 pF1KSD AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 550 560 570 580 590 600 560 570 580 590 600 610 pF1KSD TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 610 620 630 640 650 660 620 630 640 650 660 670 pF1KSD IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 670 680 690 700 710 720 680 690 700 710 720 730 pF1KSD QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 730 740 750 760 770 780 740 750 760 770 780 790 pF1KSD IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 790 800 810 820 830 840 800 810 820 830 840 850 pF1KSD GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 850 860 870 880 890 900 860 870 880 890 900 910 pF1KSD QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 910 920 930 940 950 960 920 930 940 950 960 970 pF1KSD YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KSD NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KSD IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KSD IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 pF1KSD SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL ::::::::::::::::::::::::::::::::::::::::::: XP_006 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1210 1220 1230 1240 1198 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:40:43 2016 done: Thu Nov 3 08:40:46 2016 Total Scan time: 14.810 Total Display time: 0.630 Function used was FASTA [36.3.4 Apr, 2011]