FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB1496, 277 aa 1>>>pF1KSDB1496 277 - 277 aa - 277 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2883+/-0.000835; mu= 14.9573+/- 0.050 mean_var=60.8086+/-12.023, 0's: 0 Z-trim(106.4): 19 B-trim: 43 in 1/48 Lambda= 0.164472 statistics sampled from 8926 (8939) to 8926 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.275), width: 16 Scan time: 2.060 The best scores are: opt bits E(32554) CCDS14513.1 PLP1 gene_id:5354|Hs108|chrX ( 277) 1884 455.4 2.1e-128 CCDS14514.1 PLP1 gene_id:5354|Hs108|chrX ( 242) 835 206.4 1.6e-53 CCDS48084.1 GPM6B gene_id:2824|Hs108|chrX ( 246) 503 127.6 8.3e-30 CCDS14158.1 GPM6B gene_id:2824|Hs108|chrX ( 265) 496 126.0 2.8e-29 CCDS35207.1 GPM6B gene_id:2824|Hs108|chrX ( 305) 496 126.0 3.2e-29 CCDS35206.1 GPM6B gene_id:2824|Hs108|chrX ( 328) 496 126.0 3.4e-29 CCDS54822.1 GPM6A gene_id:2823|Hs108|chr4 ( 267) 455 116.3 2.4e-26 CCDS58936.1 GPM6A gene_id:2823|Hs108|chr4 ( 271) 448 114.6 7.7e-26 CCDS3824.1 GPM6A gene_id:2823|Hs108|chr4 ( 278) 448 114.6 7.8e-26 >>CCDS14513.1 PLP1 gene_id:5354|Hs108|chrX (277 aa) initn: 1884 init1: 1884 opt: 1884 Z-score: 2418.8 bits: 455.4 E(32554): 2.1e-128 Smith-Waterman score: 1884; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD WTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 WTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLF 190 200 210 220 230 240 250 260 270 pF1KSD IAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF ::::::::::::::::::::::::::::::::::::: CCDS14 IAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF 250 260 270 >>CCDS14514.1 PLP1 gene_id:5354|Hs108|chrX (242 aa) initn: 833 init1: 833 opt: 835 Z-score: 1074.5 bits: 206.4 E(32554): 1.6e-53 Smith-Waterman score: 1538; 87.4% identity (87.4% similar) in 277 aa overlap (1-277:1-242) 10 20 30 40 50 60 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSAT---- 70 80 90 100 110 130 140 150 160 170 180 pF1KSD QKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNT ::::::::::::::::::::::::::::: CCDS14 -------------------------------FVGITYALTVVWLLVFACSAVPVYIYFNT 120 130 140 190 200 210 220 230 240 pF1KSD WTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 WTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLF 150 160 170 180 190 200 250 260 270 pF1KSD IAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF ::::::::::::::::::::::::::::::::::::: CCDS14 IAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF 210 220 230 240 >>CCDS48084.1 GPM6B gene_id:2824|Hs108|chrX (246 aa) initn: 940 init1: 503 opt: 503 Z-score: 648.6 bits: 127.6 E(32554): 8.3e-30 Smith-Waterman score: 906; 50.5% identity (72.4% similar) in 275 aa overlap (1-273:1-239) 10 20 30 40 50 60 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEY :: .::: .:: :.:.:::::: ::: :::::::::: ::.:: ..: .:: : .:. CCDS48 MGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNASDHAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGG : .::. .:::::: :::::::: .:::::::::.::... :..::: ::. .:. CCDS48 LSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGM---- 70 80 90 100 110 130 140 150 160 170 180 pF1KSD QKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNT :: .::.: :.:: ::. :::::....: CCDS48 -------------------------------FVFLTYVLGVAWLGVFGFSAVPVFMFYNI 120 130 140 190 200 210 220 230 pF1KSD WTTCQSIAFPSKTSASIG--SLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFH :.::. : : .:... : ..:.: :.::..::::::::.::: : .::.: :: :..: CCDS48 WSTCEVIKSP-QTNGTTGVEQICVDIRQYGIIPWNAFPGKICGSALENICNTNEFYMSYH 150 160 170 180 190 200 240 250 260 270 pF1KSD LFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF :::.: .::.::...:: .:.:.:::.::::. .: CCDS48 LFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF 210 220 230 240 >>CCDS14158.1 GPM6B gene_id:2824|Hs108|chrX (265 aa) initn: 926 init1: 489 opt: 496 Z-score: 639.1 bits: 126.0 E(32554): 2.8e-29 Smith-Waterman score: 899; 50.4% identity (72.3% similar) in 274 aa overlap (2-273:21-258) 10 20 30 40 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALT : .::: .:: :.:.:::::: ::: :::::::::: ::. CCDS14 MKPAMETAAEENTEQSQERKGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD GTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIF :: ..: .:: : .:. : .::. .:::::: :::::::: .:::::::::.::... CCDS14 GTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELH 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD GDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTV :..::: ::. .:. :: .::.: : CCDS14 GEFKTTACGRCISGM-----------------------------------FVFLTYVLGV 130 140 170 180 190 200 210 pF1KSD VWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIG--SLCADARMYGVLPWNAFPGKV .:: ::. :::::....: :.::. : : .:... : ..:.: :.::..::::::::. CCDS14 AWLGVFGFSAVPVFMFYNIWSTCEVIKSP-QTNGTTGVEQICVDIRQYGIIPWNAFPGKI 150 160 170 180 190 200 220 230 240 250 260 270 pF1KSD CGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF ::: : .::.: :: :..::::.: .::.::...:: .:.:.:::.::::. .: CCDS14 CGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTK 210 220 230 240 250 260 CCDS14 F >>CCDS35207.1 GPM6B gene_id:2824|Hs108|chrX (305 aa) initn: 926 init1: 489 opt: 496 Z-score: 638.2 bits: 126.0 E(32554): 3.2e-29 Smith-Waterman score: 899; 50.4% identity (72.3% similar) in 274 aa overlap (2-273:61-298) 10 20 30 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVAL : .::: .:: :.:.:::::: ::: :::: CCDS35 RYHWMYPGSKNHQYHPVPTLGDRASPLSSPGCFECCIKCLGGVPYASLVATILCFSGVAL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD FCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGF :::::: ::.:: ..: .:: : .:. : .::. .:::::: :::::::: .:::::: CCDS35 FCGCGHVALAGTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGF 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD YTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDK :::.::... :..::: ::. .:. CCDS35 YTTSAVKELHGEFKTTACGRCISGM----------------------------------- 160 170 160 170 180 190 200 pF1KSD FVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIG--SLCADARMYGV :: .::.: :.:: ::. :::::....: :.::. : : .:... : ..:.: :.::. CCDS35 FVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSP-QTNGTTGVEQICVDIRQYGI 180 190 200 210 220 230 210 220 230 240 250 260 pF1KSD LPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLK .::::::::.::: : .::.: :: :..::::.: .::.::...:: .:.:.:::.:::: CCDS35 IPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLK 240 250 260 270 280 290 270 pF1KSD LMGRGTKF . .: CCDS35 FKSREDCCTKF 300 >>CCDS35206.1 GPM6B gene_id:2824|Hs108|chrX (328 aa) initn: 776 init1: 489 opt: 496 Z-score: 637.7 bits: 126.0 E(32554): 3.4e-29 Smith-Waterman score: 859; 48.9% identity (70.7% similar) in 270 aa overlap (2-269:61-294) 10 20 30 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVAL : .::: .:: :.:.:::::: ::: :::: CCDS35 RYHWMYPGSKNHQYHPVPTLGDRASPLSSPGCFECCIKCLGGVPYASLVATILCFSGVAL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD FCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGF :::::: ::.:: ..: .:: : .:. : .::. .:::::: :::::::: .:::::: CCDS35 FCGCGHVALAGTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGF 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD YTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDK :::.::... :..::: ::. .:. CCDS35 YTTSAVKELHGEFKTTACGRCISGM----------------------------------- 160 170 160 170 180 190 200 pF1KSD FVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIG--SLCADARMYGV :: .::.: :.:: ::. :::::....: :.::. : : .:... : ..:.: :.::. CCDS35 FVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSP-QTNGTTGVEQICVDIRQYGI 180 190 200 210 220 230 210 220 230 240 250 260 pF1KSD LPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLK .::::::::.::: : .::.: :: :..::::.: .::.::...:. :.. . :.: :: CCDS35 IPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLK 240 250 260 270 280 290 270 pF1KSD LMGRGTKF CCDS35 DASKMQAYQDIKAKEEQELQDIQSRSKEQLNSYT 300 310 320 >>CCDS54822.1 GPM6A gene_id:2823|Hs108|chr4 (267 aa) initn: 447 init1: 250 opt: 455 Z-score: 586.5 bits: 116.3 E(32554): 2.4e-26 Smith-Waterman score: 674; 38.1% identity (65.8% similar) in 281 aa overlap (1-277:1-240) 10 20 30 40 50 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYF--SKNYQDY :: .::: .:: : :.:::.:: : . :::::::::::::.:: ....::: ... : CCDS54 MGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMARTAGDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD EYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVT ....: :.::::: :. ::.:: ::..:::.::::.....::.: : ::. CCDS54 LDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGR------- 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYF :.. : :. .:: . ..:: : : ...:::.:: CCDS54 ----------------------CVSAW------FIMLTYLFMLAWLGVTAFTSLPVYMYF 120 130 140 180 190 200 210 220 230 pF1KSD NTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVC--GSNLLSICKTAEFQMT : :: :. . : . ..:: : :..:.. . :.: . :.: .:...:..:: CCDS54 NLWTICR-----NTTLVEGANLCLDLRQFGIVTIGE-EKKICTVSENFLRMCESTELNMT 150 160 170 180 190 240 250 260 270 pF1KSD FHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF :::::.:..::.:...... .... . :.: .: : :. CCDS54 FHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRS 200 210 220 230 240 250 CCDS54 KERLNAYT 260 >>CCDS58936.1 GPM6A gene_id:2823|Hs108|chr4 (271 aa) initn: 440 init1: 243 opt: 448 Z-score: 577.4 bits: 114.6 E(32554): 7.7e-26 Smith-Waterman score: 667; 37.9% identity (65.7% similar) in 280 aa overlap (2-277:6-244) 10 20 30 40 50 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYF--SKN : .::: .:: : :.:::.:: : . :::::::::::::.:: ....::: ... CCDS58 MTDLEGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMART 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD YQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLS : ....: :.::::: :. ::.:: ::..:::.::::.....::.: : ::. CCDS58 AGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGR--- 70 80 90 100 110 120 130 140 150 160 170 pF1KSD ATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPV :.. : :. .:: . ..:: : : ...:: CCDS58 --------------------------CVSAW------FIMLTYLFMLAWLGVTAFTSLPV 120 130 140 180 190 200 210 220 230 pF1KSD YIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVC--GSNLLSICKTAE :.::: :: :.. : . ..:: : :..:.. . :.: . :.: .:...: CCDS58 YMYFNLWTICRN-----TTLVEGANLCLDLRQFGIVTIGE-EKKICTVSENFLRMCESTE 150 160 170 180 190 240 250 260 270 pF1KSD FQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF ..:::::::.:..::.:...... .... . :.: .: : :. CCDS58 LNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIH 200 210 220 230 240 250 CCDS58 STRSKERLNAYT 260 270 >>CCDS3824.1 GPM6A gene_id:2823|Hs108|chr4 (278 aa) initn: 440 init1: 243 opt: 448 Z-score: 577.2 bits: 114.6 E(32554): 7.8e-26 Smith-Waterman score: 667; 37.9% identity (65.7% similar) in 280 aa overlap (2-277:13-251) 10 20 30 40 pF1KSD MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIET : .::: .:: : :.:::.:: : . :::::::::::::.:: ....: CCDS38 MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD YF--SKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTT :: ... : ....: :.::::: :. ::.:: ::..:::.::::.....::.: : CCDS38 YFEMARTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKIT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD ICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVF ::. :.. : :. .:: . ..:: : CCDS38 TCGR-----------------------------CVSAW------FIMLTYLFMLAWLGVT 130 140 170 180 190 200 210 220 pF1KSD ACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVC--GSNLL : ...:::.::: :: :.. : . ..:: : :..:.. . :.: . :.: CCDS38 AFTSLPVYMYFNLWTICRN-----TTLVEGANLCLDLRQFGIVTIGE-EKKICTVSENFL 150 160 170 180 190 230 240 250 260 270 pF1KSD SICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF .:...:..:::::::.:..::.:...... .... . :.: .: : :. CCDS38 RMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEE 200 210 220 230 240 250 CCDS38 QELHDIHSTRSKERLNAYT 260 270 277 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:41:23 2016 done: Thu Nov 3 08:41:23 2016 Total Scan time: 2.060 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]