FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDB2508, 238 aa 1>>>pF1KSDB2508 238 - 238 aa - 238 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8638+/-0.000271; mu= 18.0555+/- 0.017 mean_var=73.5544+/-14.824, 0's: 0 Z-trim(120.9): 6 B-trim: 1116 in 1/53 Lambda= 0.149544 statistics sampled from 36845 (36851) to 36845 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.432), width: 16 Scan time: 7.220 The best scores are: opt bits E(85289) NP_001180233 (OMIM: 171300,613403) transmembrane p ( 238) 1599 353.2 2.3e-97 NP_060319 (OMIM: 171300,613403) transmembrane prot ( 238) 1599 353.2 2.3e-97 XP_016859940 (OMIM: 171300,613403) PREDICTED: tran ( 154) 1013 226.6 1.9e-59 XP_016859941 (OMIM: 171300,613403) PREDICTED: tran ( 154) 1013 226.6 1.9e-59 >>NP_001180233 (OMIM: 171300,613403) transmembrane prote (238 aa) initn: 1599 init1: 1599 opt: 1599 Z-score: 1868.9 bits: 353.2 E(85289): 2.3e-97 Smith-Waterman score: 1599; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238) 10 20 30 40 50 60 pF1KSD MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLV 130 140 150 160 170 180 190 200 210 220 230 pF1KSD AGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP 190 200 210 220 230 >>NP_060319 (OMIM: 171300,613403) transmembrane protein (238 aa) initn: 1599 init1: 1599 opt: 1599 Z-score: 1868.9 bits: 353.2 E(85289): 2.3e-97 Smith-Waterman score: 1599; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238) 10 20 30 40 50 60 pF1KSD MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MYAPGGAGLPGGRRRRSPGGSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 CSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLV 130 140 150 160 170 180 190 200 210 220 230 pF1KSD AGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPPAYTP 190 200 210 220 230 >>XP_016859940 (OMIM: 171300,613403) PREDICTED: transmem (154 aa) initn: 1013 init1: 1013 opt: 1013 Z-score: 1188.1 bits: 226.6 E(85289): 1.9e-59 Smith-Waterman score: 1013; 100.0% identity (100.0% similar) in 154 aa overlap (85-238:1-154) 60 70 80 90 100 110 pF1KSD HIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLD :::::::::::::::::::::::::::::: XP_016 MNPQTVLLLRVIAAFCFLGILCSLSAFLLD 10 20 30 120 130 140 150 160 170 pF1KSD VFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFA 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD VSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPP 100 110 120 130 140 150 pF1KSD AYTP :::: XP_016 AYTP >>XP_016859941 (OMIM: 171300,613403) PREDICTED: transmem (154 aa) initn: 1013 init1: 1013 opt: 1013 Z-score: 1188.1 bits: 226.6 E(85289): 1.9e-59 Smith-Waterman score: 1013; 100.0% identity (100.0% similar) in 154 aa overlap (85-238:1-154) 60 70 80 90 100 110 pF1KSD HIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLD :::::::::::::::::::::::::::::: XP_016 MNPQTVLLLRVIAAFCFLGILCSLSAFLLD 10 20 30 120 130 140 150 160 170 pF1KSD VFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFGPKHPALKITRRYAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFA 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD VSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENEPYPAEYEVINQFQPPP 100 110 120 130 140 150 pF1KSD AYTP :::: XP_016 AYTP 238 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:43:36 2016 done: Thu Nov 3 08:43:37 2016 Total Scan time: 7.220 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]