FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0106, 366 aa 1>>>pF1KSDF0106 366 - 366 aa - 366 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5436+/-0.000338; mu= -7.0717+/- 0.021 mean_var=258.2186+/-53.309, 0's: 0 Z-trim(123.7): 96 B-trim: 1125 in 1/53 Lambda= 0.079814 statistics sampled from 44013 (44130) to 44013 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.517), width: 16 Scan time: 10.790 The best scores are: opt bits E(85289) NP_789847 (OMIM: 609722) PDZ and LIM domain protei ( 366) 2442 293.7 4.6e-79 NP_067643 (OMIM: 609722) PDZ and LIM domain protei ( 602) 2175 263.0 1.2e-69 NP_932159 (OMIM: 609722) PDZ and LIM domain protei ( 278) 1660 203.5 4.6e-52 NP_055291 (OMIM: 605889) PDZ and LIM domain protei ( 364) 423 61.2 4.4e-09 XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM ( 226) 358 53.6 5.3e-07 NP_001124499 (OMIM: 166710,603422) PDZ and LIM dom ( 246) 351 52.8 9.9e-07 NP_003678 (OMIM: 166710,603422) PDZ and LIM domain ( 330) 350 52.7 1.4e-06 NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330) 306 47.7 4.6e-05 XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 306 47.7 4.6e-05 XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 306 47.7 4.6e-05 NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 309 48.1 4.7e-05 NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398) 306 47.7 5.4e-05 XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM ( 398) 306 47.7 5.4e-05 XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 310 48.3 5.5e-05 NP_001244891 (OMIM: 605889) PDZ and LIM domain pro ( 276) 301 47.1 5.9e-05 XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 310 48.3 6.5e-05 NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 307 47.9 7e-05 XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 307 47.9 7.1e-05 XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 307 48.0 8.2e-05 XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 306 47.8 8.3e-05 XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 307 48.0 8.3e-05 XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM ( 727) 306 47.9 8.9e-05 NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727) 306 47.9 8.9e-05 NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732) 306 47.9 9e-05 XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 306 47.9 9.1e-05 XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 306 47.9 9.1e-05 XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 306 47.9 9.1e-05 XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM ( 795) 306 47.9 9.6e-05 XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 306 47.9 9.8e-05 XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 306 47.9 9.8e-05 XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 297 46.8 0.00017 XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM ( 696) 297 46.8 0.00018 XP_006714133 (OMIM: 605904) PREDICTED: PDZ and LIM ( 605) 295 46.5 0.00018 XP_011529845 (OMIM: 605904) PREDICTED: PDZ and LIM ( 600) 294 46.4 0.0002 NP_001011516 (OMIM: 605904) PDZ and LIM domain pro ( 214) 280 44.6 0.00025 NP_001011515 (OMIM: 605904) PDZ and LIM domain pro ( 234) 280 44.6 0.00027 NP_001107579 (OMIM: 605889) PDZ and LIM domain pro ( 316) 283 45.0 0.00028 XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM ( 283) 279 44.5 0.00035 NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283) 279 44.5 0.00035 NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 280 44.8 0.0005 NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 280 44.8 0.00051 XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 280 44.8 0.00051 XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 280 44.8 0.00052 XP_005262753 (OMIM: 605904) PREDICTED: PDZ and LIM ( 619) 280 44.8 0.00062 NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625) 280 44.8 0.00063 XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630) 280 44.8 0.00063 NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 279 44.7 0.00067 NP_001244892 (OMIM: 605889) PDZ and LIM domain pro ( 197) 266 43.0 0.00072 NP_066272 (OMIM: 605900) PDZ and LIM domain protei ( 329) 265 43.0 0.0012 NP_998801 (OMIM: 605903) PDZ and LIM domain protei ( 222) 260 42.3 0.0013 >>NP_789847 (OMIM: 609722) PDZ and LIM domain protein 2 (366 aa) initn: 2442 init1: 2442 opt: 2442 Z-score: 1540.5 bits: 293.7 E(85289): 4.6e-79 Smith-Waterman score: 2442; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 SFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAVRI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEALEGMVEGAKRRDRRKTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 QEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEALEGMVEGAKRRDRRKTRR 310 320 330 340 350 360 pF1KSD PIQPSW :::::: NP_789 PIQPSW >>NP_067643 (OMIM: 609722) PDZ and LIM domain protein 2 (602 aa) initn: 2175 init1: 2175 opt: 2175 Z-score: 1371.1 bits: 263.0 E(85289): 1.2e-69 Smith-Waterman score: 2175; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:251-577) 10 20 30 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVT :::::::::::::::::::::::::::::: NP_067 GGSRTGRAGPSGWAPPRGARSAESTDRLKGMALTVDVAGPAPWGFRITGGRDFHTPIMVT 230 240 250 260 270 280 40 50 60 70 80 90 pF1KSD KVAERGKAKDADLRPGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 KVAERGKAKDADLRPGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQ 290 300 310 320 330 340 100 110 120 130 140 150 pF1KSD TNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 TNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAA 350 360 370 380 390 400 160 170 180 190 200 210 pF1KSD ISRSFQSLACSPGLPAADRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 ISRSFQSLACSPGLPAADRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSE 410 420 430 440 450 460 220 230 240 250 260 270 pF1KSD GGSLLLDEDSEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 GGSLLLDEDSEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSS 470 480 490 500 510 520 280 290 300 310 320 330 pF1KSD LPASRALATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWEDA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 LPASRALATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGD 530 540 550 560 570 580 340 350 360 pF1KSD CAMEGMRLSLEALEGMVEGAKRRDRRKTRRPIQPSW NP_067 ELYCEKHARQRYSAPATLSSRA 590 600 >>NP_932159 (OMIM: 609722) PDZ and LIM domain protein 2 (278 aa) initn: 1658 init1: 1658 opt: 1660 Z-score: 1055.6 bits: 203.5 E(85289): 4.6e-52 Smith-Waterman score: 1660; 93.2% identity (95.0% similar) in 279 aa overlap (1-279:1-276) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_932 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAVRI ::::::::::::::: : .: .. ::. . : NP_932 SFRLLQEALEAEERGTR---LCASRRAGTATPAATPVPTVG 250 260 270 310 320 330 340 350 360 pF1KSD QEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEALEGMVEGAKRRDRRKTRR >>NP_055291 (OMIM: 605889) PDZ and LIM domain protein 3 (364 aa) initn: 498 init1: 283 opt: 423 Z-score: 284.1 bits: 61.2 E(85289): 4.4e-09 Smith-Waterman score: 519; 31.3% identity (61.2% similar) in 345 aa overlap (1-327:1-334) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM : :: . ::::::::..:: ::. :...:... .:: :.: :::.:.::.: ..:.: NP_055 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 10 20 30 40 50 60 70 80 90 100 110 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQAT--SPGQTNGDSSLEVLATRFQGSVR--TYTESQS ::.::..:. . : :..::... :: :.. :.. . . ... . .: : . NP_055 THADAQDRIKAAAHQLCLKIDRGETHLWSP-QVSEDGKAHPFKINLESEPQDGNYFEHKH 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR-SFQSLACSPGLPAADRLSYS-- ..: .: . :. : : : . . .:... : : : : : .: .:. . NP_055 NIR---PKPFVIPGRS-SGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIP 120 130 140 150 160 170 180 190 200 210 220 pF1KSD ---GRPGSR----QAGLGRAGDSAVLVLPPSPGPRSS----RPSMDSEGGSLLLDEDSEV :: . : . : .. : :. : :. .:. .:.: NP_055 LEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASV--PPESDV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD FKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPK ..::..::. . ::::.:::.:: .. . :: : .: ... .. . : . NP_055 YRMLHDNRNEPTQPRQSGSFRVLQGMVD-DGSDDRPAGTRSVRAPVTKVHGGSGGA--QR 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD LHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEA . :.::...:.. .:. .. .:::: :..::::.::::..:.:. NP_055 MPLCDKCGSGIVGAVVKARD-KYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARART 300 310 320 330 340 350 360 pF1KSD LEGMVEGAKRRDRRKTRRPIQPSW NP_055 KPPEGYDTVTLYPKA 350 360 >>XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM dom (226 aa) initn: 341 init1: 194 opt: 358 Z-score: 246.8 bits: 53.6 E(85289): 5.3e-07 Smith-Waterman score: 375; 36.9% identity (67.0% similar) in 203 aa overlap (131-329:19-200) 110 120 130 140 150 160 pF1KSD ATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLAC :.. ::. :.:: : .:. .... : XP_011 MNLASEPQEVLHIGSAHNRSAMPFTASPASS--TTARVITNQYNNPA- 10 20 30 40 170 180 190 200 210 pF1KSD SPGLPAADRLS-YSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED :: ... .: ... :. :. : ..: : ... :: ::..:.. XP_011 --GLYSSENISNFNNALESKTAASGVEANS-------RPLDHAQPPS------SLVIDKE 50 60 70 80 90 220 230 240 250 260 270 pF1KSD SEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERG--GTPAFLPSSLSPQSSLPASRAL :::.:::::..: :.::.:: .::: ::.::.: . :. . : .: ... :: . XP_011 SEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAAS--I 100 110 120 130 140 280 290 300 310 320 330 pF1KSD ATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFW-EDACAMEGM .. :: :.::.:.:.. :.... :.::: ::.:.::: :::..:::. :: XP_011 GNAQKLPMCDKCGTGIVGVFVKLRD-RHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKH 150 160 170 180 190 200 340 350 360 pF1KSD RLSLEALEGMVEGAKRRDRRKTRRPIQPSW XP_011 ARERVTPPEGYEVVTVFPK 210 220 >>NP_001124499 (OMIM: 166710,603422) PDZ and LIM domain (246 aa) initn: 451 init1: 275 opt: 351 Z-score: 241.8 bits: 52.8 E(85289): 9.9e-07 Smith-Waterman score: 405; 33.5% identity (56.7% similar) in 284 aa overlap (1-279:1-244) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM : .: . ::.:::::..::::: .:. ...: .:: : : :::.: ::::::.: : NP_001 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS : :::..:. . : :...: .. : .. ::. .. ... .. . . : : NP_001 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 70 80 90 100 110 120 130 140 150 160 170 pF1KSD -SYSSPTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP . ..: . : :::.. :: . ..::.. ....: :: :.:: : NP_001 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPP-PSAD-------P 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAA- . :: :. : : : :::..::.: : :: NP_001 AR---GLPRSRDCRV-------------------------DLGSEVYRMLREPAEPVAAE 180 190 200 240 250 260 270 280 290 pF1KSD PRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIAN :.::.::: :: ::: : ::.:. : . .:..:.. .: NP_001 PKQSGSFRYLQGMLEAGE-GGAPS---SRHGTSSTIPSASCAVTAA 210 220 230 240 300 310 320 330 340 350 pF1KSD QAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEALEGMVEGAKRRDR >>NP_003678 (OMIM: 166710,603422) PDZ and LIM domain pro (330 aa) initn: 517 init1: 275 opt: 350 Z-score: 239.3 bits: 52.7 E(85289): 1.4e-06 Smith-Waterman score: 548; 34.3% identity (57.7% similar) in 338 aa overlap (1-329:1-297) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM : .: . ::.:::::..::::: .:. ...: .:: : : :::.: ::::::.: : NP_003 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS : :::..:. . : :...: .. : .. ::. .. ... .. . . : : NP_003 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 70 80 90 100 110 120 130 140 150 160 170 pF1KSD -SYSSPTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP . ..: . : :::.. :: . ..::.. ....: :: :.:: : NP_003 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPP-PSAD-------P 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAA- . :: :. : : : :::..::.: : :: NP_003 AR---GLPRSRDCRV-------------------------DLGSEVYRMLREPAEPVAAE 180 190 200 240 250 260 270 280 290 pF1KSD PRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATP----PKLHTCEKCST :.::.::: :: ::: : : :. :.. :.. :.. :..: : : .:. NP_003 PKQSGSFRYLQGMLEAGEGGDWPG--PGG--PRNLKPTASKLGAPLSGLQGLPECTRCGH 210 220 230 240 250 260 300 310 320 330 340 350 pF1KSD SIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWEDACAMEGMRLSLEALEGMVEGAK .:.. :. .. : :: :. :.:::::::.::.:. : NP_003 GIVGTIVKARDKLY-HPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVV 270 280 290 300 310 360 pF1KSD RRDRRKTRRPIQPSW NP_003 AVYPNAKVELV 320 330 >>NP_001073584 (OMIM: 605906,609452) LIM domain-binding (330 aa) initn: 291 init1: 266 opt: 306 Z-score: 211.9 bits: 47.7 E(85289): 4.6e-05 Smith-Waterman score: 317; 30.5% identity (59.7% similar) in 243 aa overlap (1-235:1-223) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM :. .: ..::.:::::. ::.::. :. ..... .:: ...: ::..:::.: ... : NP_001 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 10 20 30 40 50 60 70 80 90 100 110 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS : :::.::... : : :..:. : .:.. .. : :. . . .. ....: NP_001 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPAL----DTNGS 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSLA--CSPGLPAADRLSYS : . :: . :: :: .: : :.:: .:.::: .:: : :. . . NP_001 LVAPSPSPEA---RA-SPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG . :.:. .: :. : ::.: . .. .: : :. .: : . .: NP_001 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 180 190 200 210 220 240 250 260 270 280 290 pF1KSD RAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTS .:. NP_001 KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQ 230 240 250 260 270 280 >>XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM doma (330 aa) initn: 291 init1: 266 opt: 306 Z-score: 211.9 bits: 47.7 E(85289): 4.6e-05 Smith-Waterman score: 317; 30.5% identity (59.7% similar) in 243 aa overlap (1-235:1-223) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM :. .: ..::.:::::. ::.::. :. ..... .:: ...: ::..:::.: ... : XP_016 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 10 20 30 40 50 60 70 80 90 100 110 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS : :::.::... : : :..:. : .:.. .. : :. . . .. ....: XP_016 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPAL----DTNGS 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSLA--CSPGLPAADRLSYS : . :: . :: :: .: : :.:: .:.::: .:: : :. . . XP_016 LVAPSPSPEA---RA-SPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG . :.:. .: :. : ::.: . .. .: : :. .: : . .: XP_016 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 180 190 200 210 220 240 250 260 270 280 290 pF1KSD RAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTS .:. XP_016 KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQ 230 240 250 260 270 280 >>XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM doma (330 aa) initn: 291 init1: 266 opt: 306 Z-score: 211.9 bits: 47.7 E(85289): 4.6e-05 Smith-Waterman score: 317; 30.5% identity (59.7% similar) in 243 aa overlap (1-235:1-223) 10 20 30 40 50 60 pF1KSD MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM :. .: ..::.:::::. ::.::. :. ..... .:: ...: ::..:::.: ... : XP_005 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 10 20 30 40 50 60 70 80 90 100 110 pF1KSD LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS : :::.::... : : :..:. : .:.. .. : :. . . .. ....: XP_005 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPAL----DTNGS 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSLA--CSPGLPAADRLSYS : . :: . :: :: .: : :.:: .:.::: .:: : :. . . XP_005 LVAPSPSPEA---RA-SPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG . :.:. .: :. : ::.: . .. .: : :. .: : . .: XP_005 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 180 190 200 210 220 240 250 260 270 280 290 pF1KSD RAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTS .:. XP_005 KASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQ 230 240 250 260 270 280 366 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:51:44 2016 done: Thu Nov 3 08:51:45 2016 Total Scan time: 10.790 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]