FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0168, 567 aa 1>>>pF1KSDF0168 567 - 567 aa - 567 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6646+/-0.000837; mu= 17.3022+/- 0.050 mean_var=76.4387+/-15.755, 0's: 0 Z-trim(107.7): 23 B-trim: 0 in 0/50 Lambda= 0.146696 statistics sampled from 9735 (9754) to 9735 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.3), width: 16 Scan time: 3.670 The best scores are: opt bits E(32554) CCDS12787.1 IL4I1 gene_id:259307|Hs108|chr19 ( 567) 3817 817.4 0 CCDS12786.1 IL4I1 gene_id:259307|Hs108|chr19 ( 589) 3793 812.4 0 CCDS14261.1 MAOB gene_id:4129|Hs108|chrX ( 520) 400 94.2 4.1e-19 CCDS14260.1 MAOA gene_id:4128|Hs108|chrX ( 527) 356 84.9 2.6e-16 >>CCDS12787.1 IL4I1 gene_id:259307|Hs108|chr19 (567 aa) initn: 3817 init1: 3817 opt: 3817 Z-score: 4364.3 bits: 817.4 E(32554): 0 Smith-Waterman score: 3817; 100.0% identity (100.0% similar) in 567 aa overlap (1-567:1-567) 10 20 30 40 50 60 pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD EHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHD 490 500 510 520 530 540 550 560 pF1KSD LAKEEGSHPPVQGQLSLQNTTHTRTSH ::::::::::::::::::::::::::: CCDS12 LAKEEGSHPPVQGQLSLQNTTHTRTSH 550 560 >>CCDS12786.1 IL4I1 gene_id:259307|Hs108|chr19 (589 aa) initn: 3793 init1: 3793 opt: 3793 Z-score: 4336.6 bits: 812.4 E(32554): 0 Smith-Waterman score: 3793; 99.6% identity (99.8% similar) in 565 aa overlap (3-567:25-589) 10 20 30 pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ : .::::::::::::::::::::::::::::::::: CCDS12 MPNDDFCPGLTIKAMGAERAPQRQPCTLHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE 490 500 510 520 530 540 520 530 540 550 560 pF1KSD GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH 550 560 570 580 >>CCDS14261.1 MAOB gene_id:4129|Hs108|chrX (520 aa) initn: 350 init1: 197 opt: 400 Z-score: 456.6 bits: 94.2 E(32554): 4.1e-19 Smith-Waterman score: 415; 24.6% identity (55.3% similar) in 488 aa overlap (62-527:7-475) 40 50 60 70 80 90 pF1KSD PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD :.:::.:..:..:::.: :.: .:..::: CCDS14 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 10 20 30 100 110 120 130 140 150 pF1KSD NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE .:.::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:. CCDS14 DRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH 40 50 60 70 80 90 160 170 180 190 200 pF1KSD VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH :: ..: : . . . . .. . .... ... . . :: .... CCDS14 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNM 100 110 120 130 140 210 220 230 240 250 pF1KSD TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL :. : :: . .. : :: ... .....: ... . . . .. CCDS14 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG 150 160 170 180 190 200 260 270 280 290 300 310 pF1KSD QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV : ..::: . . ... :. : :. ::. . : ..: :. . : .. .: CCDS14 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY 210 220 230 240 250 320 330 340 350 360 370 pF1KSD VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S :. .: :.. .: :.:::: .. . :. . : .. ...::::.. : . CCDS14 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID 260 270 280 290 300 310 380 390 400 410 420 430 pF1KSD NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ . . : . . :: . .. . : .: :..:: :. . : . : . . CCDS14 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA 320 330 340 350 360 370 440 450 460 470 480 490 pF1KSD LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE : : : :.:.: : ... ::.. : :::::: .:: . :..: CCDS14 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME 380 390 400 410 420 430 500 510 520 530 540 pF1KSD TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP ::... ::: .: : : .. . : .. :. .: CCDS14 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG 440 450 460 470 480 490 550 560 pF1KSD PVQGQLSLQNTTHTRTSH CCDS14 LTTIFSATALGFLAHKRGLLVRV 500 510 520 >>CCDS14260.1 MAOA gene_id:4128|Hs108|chrX (527 aa) initn: 331 init1: 189 opt: 356 Z-score: 406.2 bits: 84.9 E(32554): 2.6e-16 Smith-Waterman score: 365; 25.3% identity (52.2% similar) in 490 aa overlap (62-513:16-468) 40 50 60 70 80 90 pF1KSD PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD :.:.:.:..:: :::.:.. : .: .::: CCDS14 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR 10 20 30 40 100 110 120 130 140 pF1KSD NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTK------FTQYDKN- .:.::: .: :.... .. ::. :...::: .: . ::.. : ..:: :. CCDS14 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK 50 60 70 80 90 100 150 160 170 180 190 pF1KSD ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL .:. . . : . .. ...: . : : :. : .. .... CCDS14 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM 110 120 130 140 150 200 210 220 230 240 pF1KSD KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE :.: : :. ..: ::. . :. :.: :. .: : . : CCDS14 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG-------- 160 170 180 190 200 250 260 270 280 290 300 pF1KSD ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP . : : ... : ..::: . . ... :. : :: ::. . :. .. .. . CCDS14 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KSD PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR . :..: ::: .: : : :: . .. ..:: . . : .. ... ::. CCDS14 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK 270 280 290 300 310 370 380 390 400 410 pF1KSD EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA .. : . : : . . .:.: . .. . : .: : .: : CCDS14 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL 320 330 340 350 360 370 420 430 440 450 460 470 pF1KSD LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG .: . ::: :: . : : :.:.: : ... ::.. : : CCDS14 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG 380 390 400 410 420 480 490 500 510 520 530 pF1KSD RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV ::.::: .:: :..: ::... ::: .. . : ... CCDS14 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH 430 440 450 460 470 480 540 550 560 pF1KSD ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH CCDS14 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS 490 500 510 520 567 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:53:59 2016 done: Thu Nov 3 08:53:59 2016 Total Scan time: 3.670 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]