FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0187, 563 aa 1>>>pF1KSDF0187 563 - 563 aa - 563 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9910+/-0.000452; mu= 13.2869+/- 0.028 mean_var=249.5813+/-50.575, 0's: 0 Z-trim(118.8): 2047 B-trim: 163 in 1/55 Lambda= 0.081184 statistics sampled from 29915 (32224) to 29915 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.378), width: 16 Scan time: 11.840 The best scores are: opt bits E(85289) NP_001333510 (OMIM: 601260) zinc finger protein wi ( 563) 3835 462.9 1.2e-129 NP_003430 (OMIM: 601260) zinc finger protein with ( 563) 3835 462.9 1.2e-129 XP_011514861 (OMIM: 601260) PREDICTED: zinc finger ( 563) 3835 462.9 1.2e-129 NP_001333509 (OMIM: 601260) zinc finger protein wi ( 527) 3610 436.5 9.8e-122 NP_001273983 (OMIM: 601260) zinc finger protein wi ( 527) 3610 436.5 9.8e-122 NP_001273984 (OMIM: 601260) zinc finger protein wi ( 350) 2381 292.3 1.7e-78 NP_001333508 (OMIM: 601260) zinc finger protein wi ( 321) 1801 224.4 4.5e-58 XP_006720895 (OMIM: 604191) PREDICTED: zinc finger ( 644) 1288 164.7 8.1e-40 NP_001265213 (OMIM: 194510) zinc finger protein 3 ( 446) 1231 157.8 6.7e-38 NP_001305064 (OMIM: 194510) zinc finger protein 3 ( 446) 1231 157.8 6.7e-38 NP_001265219 (OMIM: 194510) zinc finger protein 3 ( 446) 1231 157.8 6.7e-38 NP_116313 (OMIM: 194510) zinc finger protein 3 iso ( 446) 1231 157.8 6.7e-38 NP_001265216 (OMIM: 194510) zinc finger protein 3 ( 446) 1231 157.8 6.7e-38 XP_006720894 (OMIM: 604191) PREDICTED: zinc finger ( 670) 1205 155.0 7e-37 NP_001265221 (OMIM: 194510) zinc finger protein 3 ( 410) 1184 152.2 2.9e-36 XP_016868071 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1184 152.2 2.9e-36 NP_001265220 (OMIM: 194510) zinc finger protein 3 ( 410) 1184 152.2 2.9e-36 XP_006716174 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1184 152.2 2.9e-36 XP_016868072 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1184 152.2 2.9e-36 NP_001305065 (OMIM: 194510) zinc finger protein 3 ( 453) 1156 149.0 3e-35 XP_011529614 (OMIM: 300627) PREDICTED: zinc finger ( 518) 1040 135.5 4e-31 NP_689908 (OMIM: 300627) zinc finger protein 449 [ ( 518) 1040 135.5 4e-31 NP_001276331 (OMIM: 604077) zinc finger protein 13 ( 616) 940 123.9 1.5e-27 XP_016882731 (OMIM: 604077) PREDICTED: zinc finger ( 621) 940 123.9 1.5e-27 XP_016882730 (OMIM: 604077) PREDICTED: zinc finger ( 628) 940 123.9 1.5e-27 XP_016882729 (OMIM: 604077) PREDICTED: zinc finger ( 658) 940 124.0 1.5e-27 NP_001276330 (OMIM: 604077) zinc finger protein 13 ( 658) 940 124.0 1.5e-27 XP_005259268 (OMIM: 604077) PREDICTED: zinc finger ( 670) 940 124.0 1.5e-27 XP_006723426 (OMIM: 604077) PREDICTED: zinc finger ( 670) 940 124.0 1.5e-27 NP_003427 (OMIM: 604077) zinc finger protein 135 i ( 670) 940 124.0 1.5e-27 XP_006723425 (OMIM: 604077) PREDICTED: zinc finger ( 670) 940 124.0 1.5e-27 NP_009065 (OMIM: 604077) zinc finger protein 135 i ( 682) 940 124.0 1.6e-27 XP_016866755 (OMIM: 602240) PREDICTED: zinc finger ( 578) 928 122.5 3.8e-27 NP_006289 (OMIM: 602240) zinc finger protein with ( 578) 928 122.5 3.8e-27 XP_011513172 (OMIM: 602240) PREDICTED: zinc finger ( 578) 928 122.5 3.8e-27 NP_001265048 (OMIM: 602240) zinc finger protein wi ( 578) 928 122.5 3.8e-27 XP_011524533 (OMIM: 609601) PREDICTED: zinc finger ( 534) 927 122.3 3.9e-27 XP_016881531 (OMIM: 609601) PREDICTED: zinc finger ( 534) 927 122.3 3.9e-27 NP_001128650 (OMIM: 609601) zinc finger protein 39 ( 534) 927 122.3 3.9e-27 XP_006722621 (OMIM: 609601) PREDICTED: zinc finger ( 553) 927 122.3 4e-27 XP_011524531 (OMIM: 609601) PREDICTED: zinc finger ( 553) 927 122.3 4e-27 XP_011524532 (OMIM: 609601) PREDICTED: zinc finger ( 553) 927 122.3 4e-27 NP_003424 (OMIM: 604074) zinc finger protein 132 [ ( 706) 918 121.4 9.5e-27 XP_016881831 (OMIM: 614275) PREDICTED: zinc finger ( 434) 913 120.5 1.1e-26 XP_016881832 (OMIM: 614275) PREDICTED: zinc finger ( 434) 913 120.5 1.1e-26 XP_011524816 (OMIM: 614275) PREDICTED: zinc finger ( 499) 913 120.6 1.2e-26 XP_016881830 (OMIM: 614275) PREDICTED: zinc finger ( 499) 913 120.6 1.2e-26 NP_689690 (OMIM: 614275) zinc finger protein 565 [ ( 499) 913 120.6 1.2e-26 NP_001035939 (OMIM: 614275) zinc finger protein 56 ( 499) 913 120.6 1.2e-26 XP_011524814 (OMIM: 614275) PREDICTED: zinc finger ( 499) 913 120.6 1.2e-26 >>NP_001333510 (OMIM: 601260) zinc finger protein with K (563 aa) initn: 3835 init1: 3835 opt: 3835 Z-score: 2448.7 bits: 462.9 E(85289): 1.2e-129 Smith-Waterman score: 3835; 100.0% identity (100.0% similar) in 563 aa overlap (1-563:1-563) 10 20 30 40 50 60 pF1KSD MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA 490 500 510 520 530 540 550 560 pF1KSD RERASEYSPASLDAFGAFLKSCV ::::::::::::::::::::::: NP_001 RERASEYSPASLDAFGAFLKSCV 550 560 >>NP_003430 (OMIM: 601260) zinc finger protein with KRAB (563 aa) initn: 3835 init1: 3835 opt: 3835 Z-score: 2448.7 bits: 462.9 E(85289): 1.2e-129 Smith-Waterman score: 3835; 100.0% identity (100.0% similar) in 563 aa overlap (1-563:1-563) 10 20 30 40 50 60 pF1KSD MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA 490 500 510 520 530 540 550 560 pF1KSD RERASEYSPASLDAFGAFLKSCV ::::::::::::::::::::::: NP_003 RERASEYSPASLDAFGAFLKSCV 550 560 >>XP_011514861 (OMIM: 601260) PREDICTED: zinc finger pro (563 aa) initn: 3835 init1: 3835 opt: 3835 Z-score: 2448.7 bits: 462.9 E(85289): 1.2e-129 Smith-Waterman score: 3835; 100.0% identity (100.0% similar) in 563 aa overlap (1-563:1-563) 10 20 30 40 50 60 pF1KSD MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA 490 500 510 520 530 540 550 560 pF1KSD RERASEYSPASLDAFGAFLKSCV ::::::::::::::::::::::: XP_011 RERASEYSPASLDAFGAFLKSCV 550 560 >>NP_001333509 (OMIM: 601260) zinc finger protein with K (527 aa) initn: 3610 init1: 3610 opt: 3610 Z-score: 2306.5 bits: 436.5 E(85289): 9.8e-122 Smith-Waterman score: 3610; 100.0% identity (100.0% similar) in 527 aa overlap (37-563:1-527) 10 20 30 40 50 60 pF1KSD REATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFRRFCYQN :::::::::::::::::::::::::::::: NP_001 MWGQDSTLQDTPPPDPEIFRQRFRRFCYQN 10 20 30 70 80 90 100 110 120 pF1KSD TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD AVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRK 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD PRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD ARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGEKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGEKRD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD QEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD PEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRI 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD HTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGE 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD KPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASE 460 470 480 490 500 510 550 560 pF1KSD YSPASLDAFGAFLKSCV ::::::::::::::::: NP_001 YSPASLDAFGAFLKSCV 520 >>NP_001273983 (OMIM: 601260) zinc finger protein with K (527 aa) initn: 3610 init1: 3610 opt: 3610 Z-score: 2306.5 bits: 436.5 E(85289): 9.8e-122 Smith-Waterman score: 3610; 100.0% identity (100.0% similar) in 527 aa overlap (37-563:1-527) 10 20 30 40 50 60 pF1KSD REATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFRRFCYQN :::::::::::::::::::::::::::::: NP_001 MWGQDSTLQDTPPPDPEIFRQRFRRFCYQN 10 20 30 70 80 90 100 110 120 pF1KSD TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD AVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRK 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD PRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD ARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGEKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGEKRD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD QEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD PEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRI 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD HTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGE 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD KPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASE 460 470 480 490 500 510 550 560 pF1KSD YSPASLDAFGAFLKSCV ::::::::::::::::: NP_001 YSPASLDAFGAFLKSCV 520 >>NP_001273984 (OMIM: 601260) zinc finger protein with K (350 aa) initn: 2381 init1: 2381 opt: 2381 Z-score: 1530.4 bits: 292.3 E(85289): 1.7e-78 Smith-Waterman score: 2381; 100.0% identity (100.0% similar) in 350 aa overlap (214-563:1-350) 190 200 210 220 230 240 pF1KSD SRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGC :::::::::::::::::::::::::::::: NP_001 MASALFTADSQAMVKIEDMAVSLILEEWGC 10 20 30 250 260 270 280 290 300 pF1KSD QNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGE 40 50 60 70 80 90 310 320 330 340 350 360 pF1KSD KRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSN 100 110 120 130 140 150 370 380 390 400 410 420 pF1KSD FTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLH 160 170 180 190 200 210 430 440 450 460 470 480 pF1KSD QRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIH 220 230 240 250 260 270 490 500 510 520 530 540 pF1KSD TGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARER 280 290 300 310 320 330 550 560 pF1KSD ASEYSPASLDAFGAFLKSCV :::::::::::::::::::: NP_001 ASEYSPASLDAFGAFLKSCV 340 350 >>NP_001333508 (OMIM: 601260) zinc finger protein with K (321 aa) initn: 1801 init1: 1801 opt: 1801 Z-score: 1163.6 bits: 224.4 E(85289): 4.5e-58 Smith-Waterman score: 1801; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266) 10 20 30 40 50 60 pF1KSD MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE :::::::::::::::::::::::::: NP_001 WGCQNLARRNLSRDNRQENYGSAFPQANVFAAFQHAAHVFCFLEEKGHVRSCHAPEACPA 250 260 270 280 290 300 >>XP_006720895 (OMIM: 604191) PREDICTED: zinc finger pro (644 aa) initn: 1558 init1: 700 opt: 1288 Z-score: 835.8 bits: 164.7 E(85289): 8.1e-40 Smith-Waterman score: 1312; 41.3% identity (64.5% similar) in 574 aa overlap (13-543:3-562) 10 20 30 40 50 60 pF1KSD MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR : ..::..:..:::. ::: :.:. : : :.:: . ::: XP_006 MASGPGSQEREGLLIVKL----EEDCAWSQELPPPD-PGPSPEASHLRFR 10 20 30 40 70 80 90 100 110 120 pF1KSD RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR :: .:.. :::::::::.:::: :::::. :::::::::::::::.:::.:.: .:: . XP_006 RFRFQEAAGPREALSRLQELCHGWLRPEMRTKEQILELLVLEQFLTILPQEIQSRVQELH 50 60 70 80 90 100 130 140 150 160 170 pF1KSD PDSGEEAVTLLEDLELDLSG--QQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEAT-- :.::::::::.::.. .:. ::: .. .: :.: . .::. ..:: :: :. : XP_006 PESGEEAVTLVEDMQRELGRLRQQVTNHGRGTEVLLEEPLPLETARESPSFKLEPMETER 110 120 130 140 150 160 180 190 200 210 220 pF1KSD ------QSHFKHS-SRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKI : . : .: :. .. ::: : . : ::. .:. :.. : .. XP_006 SPGPRLQELLGPSPQRDPQAVKERALSAPWLSLFPPEGNMEDKEMTGP------QLPESL 170 180 190 200 210 230 240 250 260 270 280 pF1KSD EDMAVSLILEEWGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSED--- ::.:. . :::: :. ..: ::::. ::.: .. . ::.. :: :.. .. ::. XP_006 EDVAMYISQEEWGHQDPSKRALSRDTVQESYENV-DSLGEEKFENLEGVPSV-CSENIHP 220 230 240 250 260 270 290 300 310 320 pF1KSD -----SASRGETT---------GRSQKEF------GEKRDQEGKTGERQQKNPEEKTRKE . .:::. ::: .. : .. : .. :. :.: . . XP_006 QVLLPDQARGEVPWSPELGRPHDRSQGDWAPPPEGGMEQALAGASSGRELGRPKE-LQPK 280 290 300 310 320 330 330 340 350 360 370 pF1KSD KRDSGPAIGKD----KKTITGERGPREKGKGLGRS----FSLSSNFTTPEEVPTGTKSHR : : ::. .. : .: . .: . :. . : . ... : ..:. XP_006 KLHLCPLCGKNFSNNSNLIRHQRIHAAERLCMGVDCTEIFGGNPRFLSLHRAHLGEEAHK 340 350 360 370 380 390 380 390 400 410 420 430 pF1KSD CDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNEC : ::::::.... : ::. :::::::.:. ::: :: :::: ::: ::::::..: :: XP_006 CLECGKCFSQNTHLTRHQRTHTGEKPYQCNICGKCFSCNSNLHRHQRTHTGEKPYKCPEC 400 410 420 430 440 450 440 450 460 470 480 490 pF1KSD GKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAF :. :.:::::. :::::.::.::.: ::::.::.:: :. :.: : :. : ::::.: XP_006 GEIFAHSSNLLRHQRIHTGERPYKCPECGKSFSRSSHLVIHERTHERERLYPFSECGEAV 460 470 480 490 500 510 500 510 520 530 540 550 pF1KSD NRNSYLILHRRIHTREKP-YKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGA . .. .. .. : :: ..: :::.: .. :: :.: :. :. XP_006 SDSTPFLTNHGAHKAEKKLFECLTCGKSFRQGMHLTRHQRTHTGEKPYKCTLCGENFSHR 520 530 540 550 560 570 560 pF1KSD FLKSCV XP_006 SNLIRHQRIHTGEKPYTCHECGDSFSHSSNRIRHLRTHTGERPYKCSECGESFSRSSRLM 580 590 600 610 620 630 >-- initn: 411 init1: 411 opt: 411 Z-score: 280.7 bits: 62.0 E(85289): 6.7e-09 Smith-Waterman score: 411; 64.6% identity (82.9% similar) in 82 aa overlap (404-485:563-644) 380 390 400 410 420 430 pF1KSD TKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPH ::.:. ::. :: :::. ::::::::::. XP_006 KKLFECLTCGKSFRQGMHLTRHQRTHTGEKPYKCTLCGENFSHRSNLIRHQRIHTGEKPY 540 550 560 570 580 590 440 450 460 470 480 490 pF1KSD ECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSE :.::: .:::::: : : : :.::.::.:.:::..::.:: : .::: ::: XP_006 TCHECGDSFSHSSNRIRHLRTHTGERPYKCSECGESFSRSSRLMSHQRTHTG 600 610 620 630 640 500 510 520 530 540 550 pF1KSD CGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLD >>NP_001265213 (OMIM: 194510) zinc finger protein 3 isof (446 aa) initn: 2726 init1: 963 opt: 1231 Z-score: 801.4 bits: 157.8 E(85289): 6.7e-38 Smith-Waterman score: 1231; 51.5% identity (74.5% similar) in 369 aa overlap (184-546:9-369) 160 170 180 190 200 210 pF1KSD ARGMVPLDPVQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQA :..:. : . :::. ..:: . : :. NP_001 METQADLVSQEPQALLDSALPS-KVPAFSDKDSLGDEM 10 20 30 220 230 240 250 260 270 pF1KSD MASALFTADSQAMVKIEDMAVSLILEEWGCQNLARRNLSRDNRQENYGSAFPQGGENRNE .:.::. : :: .: .::.:: .: .:: . :.:.: :: ::::..: :.:.: NP_001 LAAALLKAKSQELVTFEDVAVYFIRKEWKRLEPAQRDLYRDVMLENYGNVFSLDRETRTE 40 50 60 70 80 90 280 290 300 310 320 pF1KSD NEESTSKAETSEDSASRGETTGRSQKE------FGEKRDQEGKTGERQQKNPEEKTRKEK :.. : :::. :.: :: ::. : : ..: . . ..: :. .. NP_001 NDQ-----EISEDTRSHGVLLGRFQKDISQGLKFKEAYEREVSLKRPLGNSPGERLNRKM 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD RDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFT : : . ..: : :::. :: . .: ::...::. . ...:.: . :.::::.: :. NP_001 PDFGQVTVEEKLTPRGERS--EKYNDFGNSFTVNSNLISHQRLPVGDRPHKCDECSKSFN 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD RSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSN :.:.::.:. ::::::::::.::::::: .:.:. ::::::::::.::..:::.:: :: NP_001 RTSDLIQHQRIHTGEKPYECNECGKAFSQSSHLIQHQRIHTGEKPYECSDCGKTFSCSSA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KSD LILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILH ::::.:::.::::::::::::.:: :: ::.::::::::::: :.::::::.:.: :: : NP_001 LILHRRIHTGEKPYECNECGKTFSWSSTLTHHQRIHTGEKPYACNECGKAFSRSSTLIHH 280 290 300 310 320 330 510 520 530 540 550 560 pF1KSD RRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGAFLKSCV .:::: ::::.:..:::::..:: : :.:::. :. : NP_001 QRIHTGEKPYECNECGKAFSQSSHLYQHQRIHTGEKPYECMECGGKFTYSSGLIQHQRIH 340 350 360 370 380 390 NP_001 TGENPYECSECGKAFRYSSALVRHQRIHTGEKPLNGIGMSKSSLRVTTELNIREST 400 410 420 430 440 >-- initn: 292 init1: 292 opt: 292 Z-score: 207.0 bits: 47.8 E(85289): 8.6e-05 Smith-Waterman score: 292; 72.2% identity (87.0% similar) in 54 aa overlap (435-488:370-423) 410 420 430 440 450 460 pF1KSD YECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECN : ::: :..::.:: :::::.::.::::. NP_001 YECNECGKAFSQSSHLYQHQRIHTGEKPYECMECGGKFTYSSGLIQHQRIHTGENPYECS 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD ECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGK :::::: :: :..:::::::::: NP_001 ECGKAFRYSSALVRHQRIHTGEKPLNGIGMSKSSLRVTTELNIREST 400 410 420 430 440 >>NP_001305064 (OMIM: 194510) zinc finger protein 3 isof (446 aa) initn: 2726 init1: 963 opt: 1231 Z-score: 801.4 bits: 157.8 E(85289): 6.7e-38 Smith-Waterman score: 1231; 51.5% identity (74.5% similar) in 369 aa overlap (184-546:9-369) 160 170 180 190 200 210 pF1KSD ARGMVPLDPVQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQA :..:. : . :::. ..:: . : :. NP_001 METQADLVSQEPQALLDSALPS-KVPAFSDKDSLGDEM 10 20 30 220 230 240 250 260 270 pF1KSD MASALFTADSQAMVKIEDMAVSLILEEWGCQNLARRNLSRDNRQENYGSAFPQGGENRNE .:.::. : :: .: .::.:: .: .:: . :.:.: :: ::::..: :.:.: NP_001 LAAALLKAKSQELVTFEDVAVYFIRKEWKRLEPAQRDLYRDVMLENYGNVFSLDRETRTE 40 50 60 70 80 90 280 290 300 310 320 pF1KSD NEESTSKAETSEDSASRGETTGRSQKE------FGEKRDQEGKTGERQQKNPEEKTRKEK :.. : :::. :.: :: ::. : : ..: . . ..: :. .. NP_001 NDQ-----EISEDTRSHGVLLGRFQKDISQGLKFKEAYEREVSLKRPLGNSPGERLNRKM 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD RDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFT : : . ..: : :::. :: . .: ::...::. . ...:.: . :.::::.: :. NP_001 PDFGQVTVEEKLTPRGERS--EKYNDFGNSFTVNSNLISHQRLPVGDRPHKCDECSKSFN 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD RSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSN :.:.::.:. ::::::::::.::::::: .:.:. ::::::::::.::..:::.:: :: NP_001 RTSDLIQHQRIHTGEKPYECNECGKAFSQSSHLIQHQRIHTGEKPYECSDCGKTFSCSSA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KSD LILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILH ::::.:::.::::::::::::.:: :: ::.::::::::::: :.::::::.:.: :: : NP_001 LILHRRIHTGEKPYECNECGKTFSWSSTLTHHQRIHTGEKPYACNECGKAFSRSSTLIHH 280 290 300 310 320 330 510 520 530 540 550 560 pF1KSD RRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGAFLKSCV .:::: ::::.:..:::::..:: : :.:::. :. : NP_001 QRIHTGEKPYECNECGKAFSQSSHLYQHQRIHTGEKPYECMECGGKFTYSSGLIQHQRIH 340 350 360 370 380 390 NP_001 TGENPYECSECGKAFRYSSALVRHQRIHTGEKPLNGIGMSKSSLRVTTELNIREST 400 410 420 430 440 >-- initn: 292 init1: 292 opt: 292 Z-score: 207.0 bits: 47.8 E(85289): 8.6e-05 Smith-Waterman score: 292; 72.2% identity (87.0% similar) in 54 aa overlap (435-488:370-423) 410 420 430 440 450 460 pF1KSD YECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECN : ::: :..::.:: :::::.::.::::. NP_001 YECNECGKAFSQSSHLYQHQRIHTGEKPYECMECGGKFTYSSGLIQHQRIHTGENPYECS 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD ECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGK :::::: :: :..:::::::::: NP_001 ECGKAFRYSSALVRHQRIHTGEKPLNGIGMSKSSLRVTTELNIREST 400 410 420 430 440 563 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:55:48 2016 done: Thu Nov 3 08:55:49 2016 Total Scan time: 11.840 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]